Clinical trials: Oocyte Retrieval
Infertility
Ovarian Stimulation: Inositol and Melatonin
An efficient protocol of ovarian stimulation is a key part of assisted reproductive technology. In order to obtain the highest oocyte retrieval with no adverse effects, numerous studies have evaluated the efficiency of the…
- Trial name
- NCT01267604
- Testing
- Recombinant FSH (rFSH), rFSH + Inositol + Melatonin
- Where
- 2 sites in Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- AGUNCO Obstetrics and Gynecology Centre
Infertility
Follicular Flushing Outcomes in Singles Versus Double Lumen Oocyte Retrieval Needles in Poor Responding Patients
In this study, the investigators aimed to evaluate to the efficacy of the needle type used in follicular flushing in oocyte retrieval in the poorest responders undergoing IVF.
- Trial name
- needles(opu) (NCT02391155)
- Testing
- single lumen needle in oocyte retrieval, double lumen needle in oocyte retrieval
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Baskent University
ANXIETY
Music Therapy and Sedation for Pain and Anxiety During Oocyte Retrieval
This study is a prospective observational investigation aimed at examining the effect of music intervention on anxiety and pain levels in patients undergoing the ovum pick-up (OPU) procedure under sedation at an IVF center.
- Trial name
- NCT07898358
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Samsun University
Infertility
Comparison of 2 Different Flow Rates During Oocyte Retrieval
The purpose of this study is to evaluate the effect of different flow rates during oocyte retrieval, on the number of cumulus oocyte complexes (COCs) retrieved.
- Trial name
- NCT06019494
- Testing
- Oocyte retrieval with low aspiration flow rate, Oocyte retrieval with high aspiration flow rate
- Where
- Greece
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Eugonia
Infertility
Follicular Flushing Versus Direct Aspiration
The purpose of this study is to investigate the impact of follicular flushing on the oocyte recovery rate, oocyte maturity, fertilization rate, and embryo development and utilization as compared to direct aspiration (no flushing)…
- Trial name
- NCT03354858
- Testing
- Follicular flushing
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Eugonia
Pain
A Randomized Controlled Trial of Oral Acetaminophen for Analgesic Control After Transvaginal Oocyte Retrieval
Current standard of care is no pretreatment medications before the egg retrieval, and the investigators would like to evaluate if preoperative Tylenol improves procedure and post procedure pain control over the current practice…
- Trial name
- NCT02418182
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Infertility, Female
Can Virtual Reality Technology Improve the Patient Experience in Oocyte Retrieval?
A non-pharmacological, non-blinded, randomized cohort study that will investigate the effect of Virtual Reality technology on the patient experience during oocyte retrieval.
- Trial name
- NCT05826938
- Testing
- Virtual reality technology
- Where
- Denmark
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Peter Humaidan
Infertility, Female, Anesthesia Awareness
Preoperative Anxiety at Oocyte Retrieval
This study evaluated the effects of preoperative anxiety and dosage of anesthesia on IVF success. Half of participants according to the recorded Beck's Anxiety Inventory (BAI) score: a low-anxiety group, while the other half…
- Conditions
- Infertility, Female, Anesthesia Awareness, Anxiety State
- Trial name
- NCT03134651
- Testing
- Monitoring brain function, propofol
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Trakya University
Oocyte Retrieval
Comparison of Two Different Anesthesia Methods in IVF Procedure
In this study; during the oocyte retrieval procedure, it was aimed to compare two different general anesthesia methods, in which propofol was administered as infusion according to the patient's Bispectral index system (BIS) value…
- Trial name
- NCT05631925
- Testing
- propofol bolus, propofol infusion
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Stress Reaction, Opioid Use
Effect of Fentanyl on Main Opioid Receptor (OPRM1) on Human Granulosa Cells.
Opioids is known that produce not only analgesia but also hyperalgesia through activation of central glutaminergic system-GABA. At the same time, recently it was found that the main opioid receptor (OPRM1) is present on human…
- Trial name
- NCT03248076
- Testing
- Fentanyl Citrate
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- George Papanicolaou Hospital
All Patients Undergoing Infertility Treatment
Retrospective Database Studies
Data collection and comparison of relationships between patient demographics, stimulation protocols and outcomes, retrieval and transfer outcomes, number and quality of oocytes and embryos retrieved and transferred, pregnancy…
- Trial name
- NCT01219296
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Opioid Use
Rectal Acetaminophen Use During Oocyte Retrievals to Reduce Post-Operative Opioid Utilization
The primary aim of this study is to evaluate the administration of rectal acetaminophen to current and standard anesthesia and analgesia protocol in oocyte retrievals would reduce postoperative utilization of opioids (Tylenol…
- Trial name
- NCT03732469
- Testing
- Acetaminophen, Fentanyl, Propofol
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Infertility Assisted Reproductive Technology, Oocyte Retrieval
ART Cycle Outcomes When Only 1 to 3 Oocytes Are Retrieved
This is a monocentric retrospective observational study. The study focuses on the women who underwent Assisted Reproductive Technology (ART) cycles with poor ovarian response (POR), defined as <4 oocytes retrieved.
- Trial name
- POR (NCT06950476)
- Testing
- Oocyte Retrieval
- Volunteers
- 3,761 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Infertility, In Vitro Fertilization
Virtual Reality for Acute Pain and Anxiety During Egg Retrieval for in Vitro Fertility Treatment
This study is a comparison between the current standard practice of performing a transvaginal oocyte retrieval (TVOR) with paracervical block (PCB) and a relatively recently developed technology of virtual reality that is added…
- Conditions
- Infertility, In Vitro Fertilization, IVF, ART
- Trial name
- NCT05438238
- Testing
- Oncomfort
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Pain Intensity Assessment
Pain Relief in Women Undergoing Oocyte Retrieval (OR) With Electro-acupuncture (EA) or Conscious Sedation (CS) in a Single Assisted Reproduction Centre.
This study aims to determine whether one can replace pain relief in women undergoing oocyte retrieval (OR) using electro-acupuncture (EA) instead of conscious sedation (CS).
- Trial name
- EA (NCT07041632)
- Testing
- electro-acupuncture, Conscious sedation
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Infertility, Assisted Reproductive Technology
Prognostic Value of Progesterone on Oocyte Retrieval Day for In Vitro Fertilization Outcome
This observational study aims the potential role of serum progesterone levels on the day of oocyte pick-up on the probability of pregnancy, in patients undergoing antagonist IVF cycles.
- Trial name
- NCT02109900
- Testing
- Serum Progesterone Levels
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Infertility, Female, Pain, Postoperative
Assessing Efficacy of Intravenous Acetaminophen for Perioperative Pain Control for Oocyte Retrieval
In this research study we want to learn more about how effective certain medications are at reducing pain after oocyte (egg) retrieval surgery and how effective they are at reducing the time between the retrieval and discharge…
- Trial name
- NCT03073980
- Testing
- IV Acetaminophen, PO Acetaminophen
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Ovulation, Ovulation Inhibition
Can Ibuprofen Delay Ovulation in Natural Cycle-IVF?
During natural cycle in vitro fertilisation, no gonadotropin stimulation is used to stimulate oocyte production. Ovulation is induced with HCG (human chorionic gonadotropin) and the follicle is retrieved 36 hours later.
- Conditions
- Ovulation, Ovulation Inhibition, Ovulation Inhibition/Drug Effects, Pregnancy
- Trial name
- Ibudelay (NCT02571543)
- Testing
- Ibuprofen
- Where
- Switzerland
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Infertility
The Effect of Follicular Flushing on Oocyte Retrieval Rate and Embryo Quality
Researchers will investigate the effect of flushing according to follicle size on the success of obtaining oocytes from a single follicle.
- Trial name
- NCT05584436
- Where
- Turkey (Türkiye)
- Volunteers
- 852 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Infertility (IVF Patients), Oocyte Retrieval
Impact of the Operator Performing Oocyte Retrieval on the Cumulative Live Birth Rate
This is a monocentric retrospective observational study. The study investigates the impact of the operator performing the oocyte retrieval on the cumulative live birth rate (CLBR).
- Trial name
- OPU-CLBR (NCT06933901)
- Testing
- Oocyte retrieval
- Volunteers
- 19,500 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas