Clinical trials: Opacification of Intraocular Lens
Posterior Capsule Opacification, Cataract
Posterior Capsule Opacification Development With Two Different Intraocular Lenses
Age-related cataract is the main cause of impaired vision in the elderly population worldwide. The only treatment that can restore functional visual ability is cataract surgery where the opacified crystalline lens is removed by…
- Trial name
- MIPHY (NCT01734343)
- Testing
- HOYA iMics Y-60H, PhysIOL microAY
- Where
- Austria
- Volunteers
- 65 people
- Sponsor
- Medical University of Vienna
Posterior Capsule Opacification, Postoperative Complications
Clinical Trial : Complications of in the Bag IOL Versus Optic Capture of IOL in Pediatric Cataract Surgery
This prospective, randomized, clinical trial looks to compare children undergoing congenital cataract surgery with intraocular lens (IOL) implantation in terms of visual axis obscuration as well as postoperative complications…
- Trial name
- NCT02491918
- Testing
- cataract surgery, Intraocular lens implantation
- Volunteers
- 61 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Posterior Capsule Opacification After Phacoemulsification and IOL Implantation
Long-term Evaluation of Single-piece ACrysof IOL Implantation on Development of Posterior Capsule Opacification
Although contemporary cataract surgery has made tremendous strides in technological advancement, posterior capsular opacification (PCO) is still the most frequent long-term complication leading to decreased visual functions and…
- Trial name
- NCT01820065
- Testing
- Cataract surgery with IOL implantation
- Where
- India
- Volunteers
- 390 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Cataract, Pseudophakia
Effect of Optic Edge Design in a Silicone Intraocular Lens on Posterior Capsule Opacification
Purpose: To compare the posterior capsule opacification (PCO) inhibiting effect of the sharp posterior optic edge design of the Clariflex silicone intraocular lens (IOL) with that of the double-round edge design of the SI40…
- Trial name
- NCT00428363
- Testing
- Cataract surgery with implantation of an intraocular lens
- Where
- Austria
- Volunteers
- 52 people
- Sponsor
- Medical University of Vienna
Cataract
Influence of Two Different Preloaded Intraocular Lens (IOLs) on Posterior Capsule Opacification
Studies showed that a sharp posterior optic edge of an intraocular lens (IOL) inhibits migration of lens epithelial cells in between posterior capsule and optic of the IOL and therefore reduces the rate of posterior capsule…
- Trial name
- NCT00673803
- Testing
- cataract surgery
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Hospital Hietzing
Cataract
A Prospective Observational Case Series of a Four-ring-haptic Acrylic One-piece IOL
To describe biocompatibility, postoperative results and complications after implantation of the Corneal Quatrix Evolutive (Corneal, Croma, Austria) intraocular lens, a hydrophilic acrylic intraocular lens (IOL) with 4-haptic…
- Trial name
- Qu01 (NCT01244373)
- Where
- Austria
- Volunteers
- 9 people
- Sponsor
- General Hospital Linz
Dysphotopsia, Posterior Capsule Opacification
Clinical Evaluation of Low Contrast Visual Performance and Low Light Phenomena in Patients With Various Intraocular Lens Implants
The goal of this clinical investigation is to evaluate visual acuity and contrast sensitivity in low lighting conditions using several different testing devices, and measure nighttime side effects of intraocular lens (IOL)…
- Conditions
- Dysphotopsia, Posterior Capsule Opacification, Visual Acuity, Visual Function
- Trial name
- NCT07213167
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Dr. Daniel H. Chang, MD
Cataract
Posterior Capsule Opacification Study
First object is to compare square edge PMMA with round edge PMMA IOL where the materials are same. Next objective is to compare square edge PMMA IOL with Acrysof IOL where the materials are different
- Trial name
- NCT00312299
- Testing
- Square edge PMMA IOL, Round edge PMMA IOL, Acrysof IOL
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Aurolab
Posterior Capsule Opacification
Posterior Capsule Opacification Following Cataract Surgery With Implantation of the MICS IOL L313
This study collects intra- and postoperative data from the patients´charts retrospectively and evaluates retro- and prospectively the rate of posterior capsule opacification (PCO) following implantation of the intraocular lens L…
- Trial name
- NCT03184428
- Testing
- Postoperative observation and survey
- Where
- Germany
- Volunteers
- 3,785 people
- Sponsor
- Dietrich-Bonhoeffer-Klinikum
Posterior Capsule Opacification
Quantification of Posterior Capsule Opacification in Pediatric Cataract
The purpose of this study is to quantify the opacity of posterior capsule in pediatric cataract comparing two intraocular lens materials.
- Trial name
- Cataract (NCT02968290)
- Testing
- Cataract Surgery, Alcon AcrySof SA60AT, Bausch Lomb AkreosA
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo
Macular Holes, Intraocular Lens Opacification
Oral Sedation in Vitreoretinal Surgery
The purpose of this study is to compare the efficacy of oral sedation to intravenous sedation with anesthesiology support and monitoring.
- Conditions
- Macular Holes, Intraocular Lens Opacification, Vitrectomy, Vitreous Hemorrhage
- Trial name
- NCT04346095
- Testing
- Oral Sedatives with or Without Analgesia, Intravenous Sedatives with or Without Analgesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rocky Vista University, LLC
Capsule Opacification, Tissue Adhesions
Evaluate Capsular Apposition to Intraocular Lens
In this study, the investigators examined the capsule-IOL interaction including anterior and posterior capsule adhesion, contact between posterior capsule and the posterior edge of intraocular lense (IOL), configuration of…
- Conditions
- Capsule Opacification, Tissue Adhesions, Aphakia - Lens Capsule Present, Opacification of Intraocular Lens
- Trial name
- NCT01605812
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Wenzhou Medical University
Cataract
Randomized Contralateral Clinical Trial With Single-piece (SN60WF) vs. Three Piece (MA60AC) AcrySof Intraocular Lenses (IOLs) on Development of Posterior Chamber Opacification (PCO).
Randomized contralateral clinical trial with single piece (Model SN60WF) vs. three piece (Model MA60AC) AcrySof Intraocular Lenses (IOLs) on development of Posterior Chamber Opacifiation (PCO).
- Trial name
- NCT00758745
- Testing
- Model SN60WF, Model MA60AC
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Alcon Research
Cataract, Pseudophakia
Retrospective, Non-interventional, Comparative Clinical Investigation of the Safety and Performance of 690AD and 690ADY Monofocal Intraocular Lens Implantation With Extended Patient Enrolment
Medicontur hydrophilic posterior chamber monofocal intraocular lens (IOLs) are indicated to improve vision at far distance in adults with cataract and/or ametropia (hyperopia, myopia), secondarily to removal of the crystalline…
- Conditions
- Cataract, Pseudophakia, Intraocular Lens Complication, Intraocular Lens Opacification
- Trial name
- NCT06578923
- Testing
- Standard of care, Patient satisfaction questionnare
- Where
- 2 sites in Hungary
- Volunteers
- 51 people
- Sponsor
- Medicontur Medical Engineering Ltd
Cataract, Intraocular Lens Opacification
Posterior Capsular Opacification and Glistenings in Hydrophobic and Hydrophilic Intraocular Lenses
A prospective randomized controlled clinical study to measure posterior capsular opacification, objective measurement of glistenings and intraocular lens tilt and decentration as well as visual outcomes following insertion of a…
- Trial name
- NCT04122664
- Testing
- RayOne® Hydrophobic lens 800C, RayOne® Hydrophilic lens 600C
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Cataract Complicated, Cataract Complications Operations
Performance of Two Sclera Fixated Intraocular Lens Concepts
To evaluate and compare the post-operative outcome of two different sceral fixated IOL concepts, the Yamane method (ZA9003, J\&J, USA) and the Carlevale IOL (FIL-SSF, Soleko, Italy).
- Trial name
- Carlevale (NCT05779306)
- Testing
- IOL Master 700, Casia-2, MS-39
- Where
- Austria
- Volunteers
- 26 people
- Sponsor
- Johannes Kepler University of Linz
Cataract
Glistenings and PCO Evaluation for the Envista MX60
Posterior capsule opacification (PCO) and glistenings development is among the primary reasons for sub-optimal visual capacity following cataract extraction surgery.
- Trial name
- NCT02698943
- Testing
- Phacoemulsification
- Volunteers
- 60 people
- Sponsor
- Democritus University of Thrace
Cataract, Pseudophakia
Clinical Investigation of the Safety and Performance of Model 690AD and Model 690ADY Monofocal Intraocular Lens Implantation
Medicontur hydrophilic posterior chamber monofocal intraocular lens (IOLs) are indicated to improve vision at far distance in adults with cataract and/or ametropia (hyperopia, myopia), secondarily to removal of the crystalline…
- Conditions
- Cataract, Pseudophakia, Intraocular Lens Complication, Intraocular Lens Opacification
- Trial name
- NCT05750225
- Testing
- Standard of care, Patient satisfaction questionnare
- Where
- 2 sites in Hungary
- Volunteers
- 52 people
- Sponsor
- Medicontur Medical Engineering Ltd
Posterior Capsule Opacification
Posterior Capsule Opacification and Optical Quality of Different Hydrophobic Acrylic Intraocular Lenses
The most frequent long-term complication of cataract surgery remains to be posterior capsule opacification (PCO). During the past decades many new intraocular lenses (IOL) with optimized lens material and design were introduced.
- Trial name
- NCT03831074
- Testing
- Implantation of an intraocular lenses: iMics 1 NY-60 & NY-60G
- Sponsor
- Medical University of Vienna
Cataract After, Astigmatism
Influence of Residual Astigmatism on Visual Acuity in Patients Undergoing Cataract Surgery With Trifocal Intraocular Lens Implantation
MAIN OBJECTIVE: To assess the influence of residual astigmatism on visual acuity in the different lens foci in patients operated on for cataracts with a trifocal intraocular lens implant.
- Conditions
- Cataract After, Astigmatism, IOL, Visual Acuity
- Trial name
- NCT04387721
- Testing
- Kind of trifocal IOL
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Enrique Ordiñaga-Monreal, OD, MSc