Clinical trials: Open Access
Hemodialysis Access Failure
Role of Regular Surveillance on Maintenance of Patency of an Arteriovenous Access
Chronic Kidney disease (CKD) is a worldwide public health problem that classified into five stages (1). End stage renal disease (CDK stage 5) patients require a well-functioning vascular access (VA) for successful hemodialysis…
- Trial name
- NCT04098159
- Testing
- duplex ultrasound
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assiut University
The Aim of This Study is to Follow up Short Term "3-6 Months"& Mid Term" 6-12months "Outcomes of Vascular Access" Native and Synthetic "in ESRD Pediatrics
Primary Patency in Pediatric Patients With Hemodialysis Access
Vascular access in the pediatric hemodialysis patients is a challenging,but necessary. It requires proper advance planning to assure that the best permanent access is placeds long life span.
- Trial name
- NCT06034717
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alaa Gameil Abd El-salam Hussien
Type 2 Diabetes
The Metabolite Identification and Material Balance Study of SP2086
The purpose of the study is to investigate the Metabolite identification and material balance of SP2086 in healthy adult volunteers.
- Trial name
- NCT02815748
- Testing
- SP2086
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Type 2 Diabetes
The Drug-drug Interaction of SP2086 and Simvastatin
The purpose of the study is to investigate the potential interaction between SP2086 and Simvastatin after the multiple oral doses treatment in healthy adult volunteers.
- Trial name
- NCT02815722
- Testing
- SP2086, Simvastatin
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Open Access, Medical Devices
Validation of a High-Quality Low-Cost Open-Source Electrocardiograph
The high price of electrocardiograph (ECG) devices - with most hospital-grade devices costing thousands of dollars - is one of the barriers to access of this vital technology.
- Conditions
- Open Access, Medical Devices, Low Cost, Electrocardiograph
- Trial name
- NCT04209062
- Testing
- Medical device validation
- Where
- Canada
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Intrauterine Adhesion
Assessment of Uterine Access, Uterine Patency and Intrauterine Adhesions Following Endometrial Ablation
The objective of this study is to gain information concerning the acute and longer-term morphological changes within the uterus following endometrial ablation.
- Trial name
- NCT04824430
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Rejoni Inc.
Cystic Fibrosis
(Study: Vertex IIS) Does Ivacaftor Alter Wild Type CFTR-Open Probability In The Sweat Gland Secretory Coil?
Clinical studies of lumacaftor + ivacaftor (combo therapy) produced better FEV1 (forced expiratory volume in 1 second) improvements than ivacaftor alone, without further improvement in sweat chloride results.
- Trial name
- NCT02310789
- Testing
- Ivacaftor, β-Adrenergic cocktail, Pilocarpine Nitrate 5%
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Richard Barry Moss
Colon Disease, Gastric Disease
Feasibility Trial to Evaluate the Ability of the SuMO Tissue Access and Resection System
This feasibility trial will evaluate the ability of the SuMO Tissue Access and Resection System (Apollo Endosurgery, Austin, Texas).
- Trial name
- SUMO (NCT01322737)
- Testing
- Tissue Access and Resection System
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Renal Insufficiency
SP2086 Pharmacokinetic Study in Renal Insufficiency Patients
The purpose of the study is to investigate the SP2086 pharmacokinetic in Renal Insufficiency Patients.
- Trial name
- NCT02815774
- Testing
- SP2086
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Type 2 Diabetes
The Drug-drug Interaction of SP2086 and Valsartan
The purpose of the study is to investigate the potential interaction between SP2086 and Valsartan after multiple oral doses treatment in healthy adult volunteers.
- Trial name
- NCT02815657
- Testing
- SP2086, Valsartan
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Healthy
AZD Single Ascending Dose Study In Healthy Japanese Subjects
This is a single centre, open label, non-randomised study to access the safety, tolerability, pharmacokinetics and pharmacodynamics of AZD3043 following a single dose administration to Japanese subjects.
- Trial name
- JSAD (NCT01028040)
- Testing
- AZD3043
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Mental Health
Psychotherapy Interventions to Support Transgender, Two-Spirit, and Nonbinary People of Color
The proposed research will use a community-based participatory research (CBPR) approach to engage with community organizations to design and implement a project that trains therapists to provide effective, supportive, and engaged…
- Trial name
- NCT05140174
- Testing
- Radical Healing and Internalized Stigma (RHIS) Training
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Healthy Volunteers
Study to Access the Relative Bioavailability of Subcutaneous Dose of Nemolizumab When Administered Via Auto-Injector Versus Dual-Chamber Syringe
This study was to compare the rate and extent of absorption of a single dose of nemolizumab administered with auto-injectors [AI] (test) versus dual-chamber syringes [DCS] (reference) under controlled conditions in healthy adult…
- Trial name
- NCT05405985
- Testing
- Nemolizumab
- Where
- 2 sites in United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Intervertebral Disc Degeneration, Osteoarthritis, Spine
Open Access Database of Standing Full Body Radiographs in Asymptomatic Volunteers
A study of the skeletal structure and how the structure changes over time. The aim of the study is to evaluate the skeleton in 10 year increments to determine an understanding of the normal skeleton as a person ages.
- Trial name
- NCT03076658
- Testing
- EOS imaging
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Alzheimer Disease
A Clinical Trial to Access Pharmacokinetic Profiles and Safety of IVL3003.
A Clinical Trial to Assess Pharmacokinetic Profiles and Safety of IVL3003
- Trial name
- NCT05345509
- Testing
- Aricept Tablet, IVL3003
- Where
- Australia
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Inventage Lab., Inc.
Type 2 Diabetes
The Drug -Drug Interaction of SP2086 and Glyburide
The purpose of the study is to investigate the potential interaction between SP2086 and Glyburide after the singe and multiple oral doses treatment in healthy adult volunteers respectively.
- Trial name
- NCT02815787
- Testing
- SP2086, Glyburide
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Venipuncture
Clinical Evaluation of an AI- and Ultrasound-Assisted Venipuncture Device
Purpose : This study aims to confirm the safety and efficacy of AIIV L2, an artificial intelligence- and ultrasound-based medical device that assists venipuncture, by comparing venipuncture performed using AIIV L2 with manual…
- Trial name
- NCT07383870
- Testing
- AIIV L2, Manual venipuncture
- Where
- South Korea
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Coronary Artery Disease
Acquiring Consensus for Contrast Echocardiography System Settings - ACCESS Study
This study evaluated and optimized settings for, and evaluated the performance of, AI-700-enhanced echocardiographic imaging on several ultrasound imaging platforms, as well as collected additional safety data for AI-700 in…
- Trial name
- NCT00669851
- Testing
- AI-700
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Acusphere
Type 2 Diabetes Mellitus
A Clinical Study to Access the Pharmacokinetics of HMS5552 in Hepatic Impaired Subjects and Healthy Volunteers
The objectives of this study is to access the pharmacokinetics and safety of HMS5552 in single dose in mild and moderate hepatic impaired subjects and matched healthy adult subjects.
- Trial name
- NCT04426708
- Testing
- HMS5552
- Where
- China
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Hua Medicine Limited
Hypertension, Diabetes
Assessing Open Access Audio
The medical encounter can be overwhelming in term of the amount of information discussed, its technical nature, and the anxiety it can generate.
- Trial name
- OAA (NCT04452331)
- Testing
- Open Access Audio, No Access, Patient and Provider Aware of Recording, No Access, Provider Unaware of Recording
- Where
- 2 sites in United States
- Volunteers
- 1,553 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development