Clinical trials: Open Fracture
Surgery Complications, Surgery
SurgWeek-2: Identifying the Global Burden of Post Operative Complications: an International Prospective Cohort Study Protocol
This study aims to assess and improve the global outcomes following surgery. Every year approximately 313 million operations are performed, with 50 million people experiencing a complication and unfortunately 3.5 million people…
- Conditions
- Surgery Complications, Surgery, Global Surgery, Robotic
- Trial name
- SurgWeek-2 (NCT07785076)
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Mandibular Body Fracture
3D Titanium Plates for Mandibular Body Fracture Fixation
Mandibular body fracture pose significant challenges in maxillofacial surgery due to their frequency, potential for functional impairment, and aesthetic concerns.
- Trial name
- NCT07651059
- Testing
- 3D Titanium Plates
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Cairo University
Disc Degenerative Disease, Spondylolisthesis
A Clinical Study of a Spine Fusion System in Vertebral Body Fusion Surgery
The primary objective of this study is to demonstrate that the efficacy and safety of Spine fusion system manufactured in China is no inferior than imported product.
- Conditions
- Disc Degenerative Disease, Spondylolisthesis, Spinal Fracture, Spinal Deformity
- Trial name
- NCT02252185
- Testing
- Johnson&Johnson Medical Suzhou made Spine Fusion System, Imported EXPEDIUM screws and OPAL cage
- Where
- 8 sites in China
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Medical (Suzhou) Ltd.
Hand Fractures
The Efficacy and Safety of Magnesium Alloy Screw as a Novel Bioabsorbable Material in Patients Due to Hand Fractures
This study evaluates the safety and efficacy of biodegradable magnesium alloy screw, in patients with hand fractures who require internal fixation (to obtain a product license from the Ministry of Food and Drug Safety in Korea…
- Trial name
- NCT02456415
- Testing
- K-MET™ Bioresorbable Bone screw
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- U&I Corporation
Femoral Neck Fractures
Open Reduction in Femoral Neck Fractures
Outcomes of open reduction and internal fixation of femoral neck fractures using dynamic hip screw versus cannulated screws combined with medial buttress plate.
- Trial name
- OR FNFS (NCT06872970)
- Testing
- Open reduction of femoral neck fractures and internal fixation by dynamic hip screws, Open reduction of femoral neck fractures using watson jones or smith peterson approachand internal fixation by cannulated screws and medial buttress plate
- Where
- Egypt
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Samer youssef mansour meglaa
Condylar Process of Mandible Open Fracture
Condylar Head Operative or Conservative 1
The condylar head is the part of the lower jaw which forms the joint. Displaced fractures of this area are uncommon but can cause problems with function, such as chewing, if not treated effectively.
- Trial name
- CHOC1 (NCT03264196)
- Testing
- Open Reduction and Internal Fixation
- Where
- 2 sites in United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Hypoparathyroidism, Osteoporosis
Assess Safety and Compare PK of New Oral hPTH(1-34) Tablet Formulations vs. EBP05 Tablets and Subcutaneous Forteo
The purpose of this study is to characterize and compare the pharmacokinetics of hPTH(1 34) after treatment with modified oral formulations (EBP11, EBP11-F1, EBP11-F2, EBP11-F4, EBP11-F5 and EBP22) versus three dose levels of…
- Conditions
- Hypoparathyroidism, Osteoporosis, Fractures, Bone, Other Disease
- Trial name
- NCT05965167
- Testing
- EBP05, Forteo 0.02 mg, EBP11
- Where
- Israel
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Entera Bio Ltd.
Proximal Humeral Fracture
Proximal Humerus Fractures: A Retrospective Analysis
The purpose of this study is to evaluate preoperative objective measurements of patients with a proximal humerus fracture and operative objective measurements to determine if there is any effect to postoperative outcomes.
- Trial name
- PHFx (NCT03637608)
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- The Orthopaedic Research & Innovation Foundation
Open Fracture of Tibia
Role of Vacuum in Open Fracture Tibia Grade III Type B
Evaluate the role of VAC in decreasing the time needed for soft tissue coverage and definitive fixation in open IIIB tibial fractures
- Trial name
- NCT04063111
- Testing
- vacuum assistant closure, CONVENTIONAL DRESSING
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Open Fracture of Foot
In Vivo Clinical Trial of Porous Starch - Hydroxyapatite Composite Biomaterials for Bone Regeneration
Biodegradable scaffold is an accepted and commercialized medical alternative choice for bone regeneration. In this project we will used our new invention, porous starch- hydroxyapatite composite, for in vivo clinical trial.
- Trial name
- NCT02910232
- Testing
- bone void filler
- Where
- Thailand
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Mandibular Fractures, Symphysis Fractures
Evaluation of Pin Buckle Bone Plates for Management of Anterior Mandibular Fractures
This randomized clinical study aims to evaluate the clinical and radiographic outcomes of a novel Pin Buckle bone plate compared with conventional two-miniplate fixation for the management of anterior mandibular (symphysis and…
- Conditions
- Mandibular Fractures, Symphysis Fractures, Parasymphysis Fractures
- Trial name
- NCT07736430
- Testing
- Pin Buckle Bone Plate, Conventional Titanium Miniplates
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Lateral Malleolus Fracture, Minimally Invasive Surgical Procedure
Comparison of Patients Who Underwent Open and Minimally Invasive Fixation in Lateral Malleolar Fractures
The aim of this study was to compare the postoperative clinical, functional and radiological results of two different surgical methods, minimally invasive percutaneous plate osteosynthesis method and open reduction-internal…
- Conditions
- Lateral Malleolus Fracture, Minimally Invasive Surgical Procedure, Postoperative Pain, Patient Discharge
- Trial name
- NCT06753656
- Testing
- Open Surgery, Minimally Invasive Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Giresun University
Tibia Fracture
Ilizarov Frame or Uni Planar External Fixator in the Cost-conscious Era
Tibial shaft fracture is a common injury worldwide. Their treatment, prognosis, and outcome are determined by the mechanism of injury, presence of communition, soft tissue injury and displacement.
- Trial name
- NCT03936972
- Testing
- ilizarov circular frame and uni-planarexternal fixator
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Distal Radius Fractures, Wrist Fracture
Unstable Distal Radius Fractures With Dorsal Dislocation in Patients Aged 18-64 Years. Volar Locking Plate (VLP) vs Closed Reduction and Percutaenous Pinning (CRPP).
120 patients age 18-64 years with dorsally displaced distal radius fractures AO-type A2, A3 and C1 are recruited from Oslo Casualty Medical Centre (Oslo Skadelegevakt).
- Conditions
- Distal Radius Fractures, Wrist Fracture, Colles' Fracture
- Trial name
- NCT04716309
- Testing
- Open reduction and volar locking plate and closed reduction and K-wires.
- Where
- Norway
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Scoliosis, Scoliosis; Adolescence
Study Comparing the PathKeeper System for Pedicle Screw Positioning in Spine Surgery With Traditional Care
The goal of this is to evaluate performance of the Pathkeeper Surgical System. The main question[s]it aims to answer are: 1) evaluate pedicle screw position Participants will in compare Experimental arm: PathKeeper System (PKS)…
- Conditions
- Scoliosis, Scoliosis; Adolescence, Scoliosis Kyphosis, Scoliosis Lumbar Region
- Trial name
- PKSforPSP (NCT06554093)
- Testing
- Medical Device - PKS
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Deep Health Ltd.
Fragility Ankle Fractures and Complex Distal Tibial Fractures
Tibio-talo-calcaneal Fusion by Hindfoot Nail Versus Open Reduction and Internal Fixation in Treatment of Complex Fractures Distal Tibial and Fragility Ankle Fractures in Elderly
Tibiotalar calcaneal fusion by hindfoot nail Vs open reduction and internal fixation in treatment of complex distal tibial fractures and ankle fragility ankle fractures in elderly
- Trial name
- NCT06709365
- Testing
- Tibiotalar calcaneal fusion by hindfoot
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sohag University
Educational Problems, Simulation of Physical Illness
Learning Management of Open Fractures on Virtual Patient
A novel virtual world programme with over 240 multiple choice questions was developed to assess the competencies in managing an open fracture of the lower limb according to the British Orthopaedic Association Standards for Trauma…
- Conditions
- Educational Problems, Simulation of Physical Illness, Fractures, Bone, Emergencies
- Trial name
- NCT04605380
- Testing
- Virtual reality online world
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Open Fractures
Antibiotic Prophylaxis in Open Fractures
Prospective look at antibiotic prophylaxis with Ceftaroline in patients with type II and III open fractures
- Trial name
- NCT02937181
- Testing
- Ceftaroline
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Olayemi Osiyemi MD
Femoral Neck Fractures
Open vs Closed Reduction in Femoral Neck Fractures Using Anterolateral vs Direct Lateral Approach
Outcomes of open vs closed reduction if emoral neck fractures
- Trial name
- FNFs (NCT07299370)
- Testing
- Closed reduction of femoral neck fractures, Open reduction of femoral neck fractures
- Where
- Egypt
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Samer youssef mansour meglaa
Deep Venous Thrombosis
Low-Molecular-Weight Heparin (LMWH) for Deep Venous Thrombosis (DVT) Prophylaxis
1. The use of LMWH following open reduction and internal fixation of ankle fractures will reduce the number of thrombi formed. 2. The rates of clinically significant DVT will be equivalent between two groups.
- Trial name
- NCT01029821
- Testing
- Low-Molecular-Weight Heparin
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Tennessee