Clinical trials: Open Surgery
Colostomy Stoma
NM-IL-12 (rHuIL-12) in Subjects With Open Surgical Wounds
The purpose of this study is to determine the safety and tolerability of NM-IL-12 relative to standard of care (SOC; control) in subjects with open surgical wounds.
- Trial name
- NCT02544061
- Testing
- NM-IL-12
- Where
- 3 sites in United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Neumedicines Inc.
Post-operative Infections
Reduction in IV Associated Contamination
The purpose of this study is to investigate whether implementing a novel syringe and IV stopcock cap system impregnated with alcohol will reduce IV catheter bacterial contamination and infections in patients.
- Trial name
- NCT01426217
- Testing
- Passive Bundle PSI (Problem Solving Innovations) Medical HubScrub, PSI Medical DocIt
- Where
- United States
- Volunteers
- 594 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Renal Function Test, Urine Output, Lactate Level
Dopamine and Norepinephrine Infusion With Restricted Hydration
This study was designed to assess the effect of adding dopamine infusion in addition to restrictive hydration combined with noradrenaline infusion on intraoperative serum lactate levels as an indicator for tissue hypo perfusion…
- Trial name
- NCT03780686
- Testing
- Norepinephrine, dopamine
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Safety, Availability
The Parietal Peritoneum as a Substitute Graft for Venous Reconstruction in HPB Surgery
To evaluate the safety and outcome of the parietal peritoneum for venous reconstruction HPB surgery. Although the parietal peritoneum had already been used and published for the reconstruction of the vena cava, however this one…
- Conditions
- Safety, Availability, Venous Patency, Oncological Benefits
- Trial name
- NCT02121886
- Testing
- venous reconstruction with the parietal peritoneum
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Beaujon Hospital
Nursing Care, Massage
Effect of Massage After CABG on Pain, Sleep Quality and Serum Cortisol Level
The patient in the surgical treatment and care process has difficulty in meeting the need for sleep in the hospital, and accordingly, their habits, attitudes and behaviors regarding sleep and rest change.
- Conditions
- Nursing Care, Massage, Pain, Cortisol
- Trial name
- NCT06529471
- Testing
- Massage group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Open Heart Surgery, Anxiety
Mindfulness-Based Nursing Care and Anxiety in Open Heart Surgery Patients
This randomized controlled trial aims to evaluate the effect of a mindfulness-based nursing intervention on anxiety levels and vital signs in patients undergoing open-heart surgery during the preoperative and early postoperative…
- Trial name
- OH-MIND (NCT07397052)
- Testing
- Mindfulness-Based Nursing Intervention Group, Standard Care Control Group
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mersin University
Ureteric Injury, Surgery
Fluorescent Imaging & Methylene Blue: Ureter Study
The main aim of this project is to assess whether intravenous methylene blue can help identify the ureters during open and laparoscopic (keyhole) surgery.
- Conditions
- Ureteric Injury, Surgery, Surgery--Complications
- Trial name
- NCT03177070
- Testing
- Methylene Blue
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Primary Open Angle Glaucoma (POAG)
One, Two, or Three iStents for the Reduction of Intraocular Pressure in Open-angle Glaucoma Subjects
The purpose of this study is to evaluate the safety and efficacy of the intraocular pressure (IOP) lowering effect of one, two, or three iStent devices in eyes of subjects previously on two anti-glaucoma medications.
- Trial name
- NCT01517477
- Testing
- iStent
- Where
- Armenia
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Glaukos Corporation
Hemorrhoids
Laser Hemorrhoidoplasty Versus Open Surgical Hemorrhoidectomy in Second and Third Degree Piles
The study aims to compare the pain , duration of intervention and long term outcomes of laser hemorrhoidoplasty versus open surgical hemorrhoidectomy
- Trial name
- NCT05770141
- Testing
- laser hemorrhoidoplasty, open surgical hemorrhoidectomy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Sternotomy Closure,Open Heart Surgery
Comparison Between Interlocking Multi-twisted Wires and Eight Figure of Sternum Closure
Comparison between interlocking multi-twisted wires and Eight figure of sternum closure post open heart surgery in egptian patients
- Trial name
- NCT03343990
- Testing
- Interlocking multi-twisted wires in sternal closure, Eight Figure techniqe in sternal closure
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Radiculopathy, Herniated Disk
Percutaneous Diskectomy SpineJet x Open Microdiskectomy in Treatment of Lumbar Radiculopathy
Approximately 300,000 patients undergo open surgical procedures to treat symptoms caused by disc herniation. Among the various surgical techniques practiced the percutaneous discectomy occupies its space since the first…
- Trial name
- PDOP_TLR (NCT01367860)
- Testing
- Open microdiscectomy, Percutaneous Diskectomy SpineJet
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Colorectal Surgery
Efficacy Comparison of Two Preoperative Skin Antisepsis Preparations in Colorectal Surgery
Surgical site infections (SSI) are one of the most common complications in the post-operative patient, and the second most common health care associated infection overall.
- Trial name
- NCT01233050
- Testing
- 2% Chlorhexidine Gluconate/70% Isopropyl Alcohol, Iodine Povacrylex/74% Isopropyl Alcohol
- Where
- 3 sites in United States
- Volunteers
- 802 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Open Heart Surgery Patients
Patient Education by Mobile Application
Cardiovascular diseases are among the important health problems that cause mortality and morbidity both in our country and in the World (Sidar vd 2013).
- Trial name
- NCT05094063
- Testing
- patient education by mobile application
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Betul Zeynep Yildiz
Distal Cholangiocarcinoma
Minimally Invasive Pancreatoduodenectomy for Distal Cholangiocarcinoma
Outcomes for minimally invasive and open pancreatoduodenectomy for distal cholangiocarcinoma have not been compared. This is an international multicenter propensity score matched cohort study including patients after MIPD or OPD…
- Trial name
- NCT05478889
- Testing
- Minimally invasive pancreatoduodenectomy
- Where
- Italy
- Volunteers
- 478 people, healthy volunteers welcome
- Sponsor
- Fondazione Poliambulanza Istituto Ospedaliero
Surgical Blood Loss, Spinal Surgery
Efficacy of Suction Enabled Retraction Device
This is a prospective randomized controlled trial of the Suction-Integrated Surgical Tissue Elevator \& Retractor [SISTER] device to assess: Effects on operative time and efficiency of exposure in open lumbar spine cases.
- Trial name
- NCT03160170
- Testing
- SISTER device
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Miami
Colorectal Cancer, Liver Metastasis
Surgical Recovery After Left Lateral Hepatic Sectionectomy: Laparoscopic Versus Open Surgery.
The ORANGE II trial is a double blinded randomised controlled trial that will provide evidence on the merits of laparoscopic surgery in patients undergoing a left lateral hepatic sectionectomy in terms of time to functional…
- Conditions
- Colorectal Cancer, Liver Metastasis, Liver Disease
- Trial name
- ORANGE II (NCT00874224)
- Testing
- laparoscopic left lateral hepatic sectionectomy, open left lateral hepatic sectionectomy
- Where
- Netherlands
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Glaucoma
Reduction of Intraocular Pressure After I-stent By-pass Implantation in Eyes With Open Angle Glaucoma
Purpose of this study is to exam the hypotensive effectiveness of I-stent implantation depended on number of antiglaucoma eye drops at baseline.
- Trial name
- NCT03807869
- Testing
- combined glaucoma surgery
- Where
- Poland
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Wound of Skin, Wound Heal
Efficacy and Safety of 0.25% Timolol Gel in Healing Surgical Open Wounds
The use of topical beta-blockers, such as 0.25% timolol, in promoting wound healing is currently emerging in the academic literature.
- Conditions
- Wound of Skin, Wound Heal, Wound Open, Surgical Wound
- Trial name
- NCT03452072
- Testing
- 0.25% Timolol gel with paraffin gauze dressings, Vaseline dressing
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Hypoactive Sexual Desire Disorder
A Pharmacokinetic (PK) Study to Compare the Absorption of Two Formulations of Transdermal Testosterone Spray and Intrinsa®
The purpose of this study is to determine if the absorption of the testosterone spray is the same as the Intrinsa® Patch.
- Trial name
- NCT01096329
- Testing
- Testosterone Spray 5% and 1%, Intrinsa® Patch and Testosterone Spray 5%, Intrinsa® Patch and Testosterone Spray 1%
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- VIVUS LLC
Lateral Malleolus Fracture, Minimally Invasive Surgical Procedure
Comparison of Patients Who Underwent Open and Minimally Invasive Fixation in Lateral Malleolar Fractures
The aim of this study was to compare the postoperative clinical, functional and radiological results of two different surgical methods, minimally invasive percutaneous plate osteosynthesis method and open reduction-internal…
- Conditions
- Lateral Malleolus Fracture, Minimally Invasive Surgical Procedure, Postoperative Pain, Patient Discharge
- Trial name
- NCT06753656
- Testing
- Open Surgery, Minimally Invasive Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Giresun University