Clinical trials: Operation Time
Surgical Wounds
Evaluation of a 'Hand-Held' Fluorescence Digital Imaging Device for Real-Time Advanced Wound Care Monitoring (SMH/UHN)
Currently, standard wound care practice is suboptimal at assessing wound remodeling and bacterial infection in real-time. An alternative and complimentary means of providing real-time imaging of connective tissue re-modeling and…
- Trial name
- SMH/UHN (NCT01650571)
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- University Health Network, Toronto
Congenital Heart Disease
Application of a Clinical Decision Support System to Reduce Mechanical Ventilation Duration After Cardiac Surgery in Children
The goal of this study is to evaluate the impact of a clinical decision support system (CDSS) in children receiving mechanical ventilation (MV) after surgery for congenital heart disease (CHD).
- Trial name
- NCT05687292
- Testing
- Clinical decision support system (CDSS) for ventilator weaning
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- Boston Children's Hospital
Achilles Tendon Rupture
Comparison of Therapeutic Effect of Different Brace Fixed Time After Novel Achilles Tendon Rupture Surgery
This study is a prospective randomized controlled clinical study. After the novel Achilles tendon rupture repaired , patients were randomly divided into 4 groups according to immobilisation duration of 0, 2, 4, and 6 weeks…
- Trial name
- NCT04956614
- Testing
- immobilisation duration
- Where
- China
- Volunteers
- 266 people
- Sponsor
- Peking University Third Hospital
Lower Extremity, Nerve Block
Bupivacaine-Lidocaine vs Bupivacaine for Ultrasound-Guided Popliteal Sciatic Nerve Block
This prospective, randomized, double-blind clinical trial aims to compare the efficacy of two local anesthetic regimens for ultrasound-guided popliteal sciatic nerve block in adult patients undergoing elective distal lower…
- Conditions
- Lower Extremity, Nerve Block, Pain, Postoperative, Pain, Nerve
- Trial name
- PSSNB-BL (NCT07550348)
- Testing
- Bupivacaine-Lidocaine Combination, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Morbid Obesity
Effect of Positive End Expiratory Pressure at the Time of Induction in Morbidly Obese Patients
Background: Positive end expiratory pressure (PEEP) at the time of induction increases oxygenation by preventing lung atelectasis. However, PEEP may not prove beneficial in all cases.
- Trial name
- NCT03024658
- Testing
- positive end expiratory pressure (PEEP)
- Volunteers
- 70 people
- Sponsor
- Sri Aurobindo Institute of Medical Sciences
RCC, Renal Cell Cancer
Comparison of Outcomes and Surgical Time Between Cortical and Medullary Suture vs. Medullary-Only Suture: Cortex Clinical Trial
Renal function preservation is a growing concern in the surgical management of kidney tumors, particularly with the rise in chronic kidney disease worldwide.
- Trial name
- CORTEX (NCT07190638)
- Testing
- Medullary-only suturing (single-layer), Suture, Medullary and cortical suturing (two-layer)
- Where
- 2 sites in Brazil
- Volunteers
- 80 people
- Sponsor
- Brazilian Institute of Robotic Surgery
Prostatic Neoplasm, Urinary Bladder Neoplasm
The Effect of Prolonged Inspiratory Time on Gas Exchange During Robot-assisted Laparoscopic Surgery With Steep Trendelenburg Position : A Crossover Randomized Clinical Trial
Gas exchange disturbance frequently occurs in steep Trendelenburg position during robot-assisted laparoscopic prostatectomy or cystectomy.
- Trial name
- NCT02966535
- Testing
- Adjustment of Mechanical Ventilator Inspiratory to expiratory time ratio (1:2 to 1:1), Adjustment of Mechanical Ventilator Inspiratory to expiratory time ratio (1:1 to 1:2)
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Fluorescence Guided Surgery
Feasibility Trial for Real-time Identification of the Ureters With a Methylene-blue
This is a non-randomized prospective, open label, single site study to evaluate the feasibility of recruitment for the use of an Investigational Endoscopic Fluorescence Imaging System, PINPOINT, in intraoperative bilateral…
- Trial name
- TRIUMPh (NCT05111808)
- Testing
- Methylene blue fluorescence
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University College, London
Glioma, Coagulopathy
Hemostasis Alterations in Neurosurgical Patients
Prospective, observational study aimed to investigate the specific hemostatic alterations in patients undergoing glial tumor resection.
- Conditions
- Glioma, Coagulopathy, Acquired Platelet Function Disorder, Thromboelastometry
- Trial name
- ABCD (NCT02652897)
- Testing
- Exposure to glioma resection surgery, Exposure to colon resection surgery
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Santiago R. Leal-Noval
Coronary Disease, Cardiovascular Diseases
Effects of Improved Environment on Sleep, Anxiety-Depression
The aim of this randomized controlled trial was to examine the effect of an improved environment on sleep, anxiety, and depression in patients undergoing open heart surgery.
- Trial name
- NCT06744023
- Testing
- To examine the effect of the improved environment according to Watsons Human Care Theory on sleep quality, anxiety, and depression in patients undergoing open heart surgery.
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hatice AZİZOĞLU
Coronary Artery Bypass Graft (CABG), Postoperative Pain
Multimodal Fascial Plane Block for Postoperative Analgesia in Isolated CABG Surgery
Postoperative pain following coronary artery bypass grafting (CABG) via median sternotomy remains a significant clinical problem and is associated with increased opioid consumption and postoperative complications.
- Conditions
- Coronary Artery Bypass Graft (CABG), Postoperative Pain, Sternotomy
- Trial name
- BLOCKCABG (NCT07587320)
- Testing
- Multimodal Fascial Plane Block Package, Standard Postoperative Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Saglik Bilimleri Universitesi
Anesthesia; Reaction
Endotracheal Intubation With Sevoflurane in Surgical Pediatric Patients
Aim of the study is to compare the optimal time needed for successful tracheal intubation with immediate 8% sevoflurane and incremental sevoflurane induction in surgical pediatric patients undergoing adenotonsillectomy without…
- Trial name
- NCT02429323
- Testing
- Sevoflurane
- Volunteers
- 100 people
- Sponsor
- University of Sulaimani
Residual Paralysis, Post Anesthesia, Postoperative Complications
Predicting Neuromuscular Recovery in Surgical Patients Using Machine Learning
Despite emerging efforts to decrease residual paralysis and postoperative complications with the use of quantitative neuromuscular monitoring and reversal agents their incidences remain high.
- Conditions
- Residual Paralysis, Post Anesthesia, Postoperative Complications, Neuromuscular Blockade, Quantitative Neuromuscular Monitoring
- Trial name
- PINES (NCT05471882)
- Where
- 2 sites in Germany
- Volunteers
- 240,000 people
- Sponsor
- University Hospital Ulm
Duration of Hospitalization in Intensive Care Unit
Evaluation of the Effectiveness of the Administration of Local Anesthetics Via Two Catheters Placed During Surgery, and Study of the Benefits on Respiratory Function and Therefore on Recovery Time
Currently intravenous analgesics are used for postoperative analgesia. But the analgesia of these products is tempered by their adverse effects (sedation, confusion, nausea or vomiting, delayed transit, urinary retention and…
- Trial name
- PARALSTER (NCT06463899)
- Testing
- multi-perforated catheter, Classic procedure
- Where
- France
- Volunteers
- 114 people
- Sponsor
- CHU de Reims
Non-surgical Retreatment
Effects of Different NiTi Systems on Postoperative Pain and Operation Time in Nonsurgical Endodontic Retreatment
This prospective, randomized, single-center, single-blind clinical trial evaluated the effects of different nickel-titanium retreatment and final shaping systems on postoperative pain and operation time during single-visit…
- Trial name
- NiTi-RETREAT (NCT07783945)
- Testing
- ProTaper Universal Retreatment System, MicroMega REMOVER, ProTaper Next
- Where
- Turkey (Türkiye)
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma
Real-time Margin Assessment in Head and Neck Cancer
To investigate if the combination of fresh frozen sectioning based on cetuximab-800CW can enhance tumor-positive margin detection intra-operatively.
- Trial name
- LIGHTNING (NCT05499065)
- Testing
- Fluorescence guided detection of tumor positive margins, Cetuximab-IRDye800
- Where
- Netherlands
- Volunteers
- 23 people
- Sponsor
- University Medical Center Groningen
Detection of Surgical Smoke Gas Using AI
AI-Based Real-Time Detection of Surgical Smoke Using Endoscopic Data
The goal of this observational, prospective monocentric pilot study is to generate a pilot dataset to train a computer-assisted model for automatic, intraoperative detection of surgical smoke gas.
- Trial name
- NCT07397000
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital Tuebingen
Diabetes, Bariatric Surgery
Extending Time Without Diabetes After Bariatric Surgery: a Trial Comparing the Metformin Addition or Not to Standard Care
This study is a randomized trial that evaluates the effect of metformin addition or not to standard care on the duration of diabetes remission after bariatric surgery.
- Conditions
- Diabetes, Bariatric Surgery, Metformin
- Trial name
- DiabOUT (NCT04581447)
- Testing
- Metformin, Standard Care, Standardized meal
- Where
- 16 sites in France
- Volunteers
- 126 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Osteoarthritis
Effect of Exercise as Non-surgical Treatments on Time to Total Hip Replacement Surgery
The aim of this trial is to test the hypothesis that patients with severe hip osteoarthritis postpone time to hip replacement surgery following participation in a patient education and supervised exercise program when compared to…
- Trial name
- HipSPORT (NCT01697241)
- Testing
- Supervised exercise, Patient education
- Where
- 2 sites in Denmark
- Volunteers
- 110 people
- Sponsor
- University of Southern Denmark
Nerve Block, Anesthesia, Local
Combining Lidocaine and Ropivacaine for an Infraclavicular Brachial Plexus Nerve Block
The aim of the study is to investigate how the combination of ropivacaine (a slow onset, long duration local anesthetic) with lidocaine (a rapid onset, shorter duration local anesthetic) affects the onset and duration of a…
- Conditions
- Nerve Block, Anesthesia, Local, Forearm Fracture, Surgery
- Trial name
- NCT06381622
- Testing
- Ropivacaine 0.5% Injectable Solution, Lidocaine epinephrine, Ropivacaine 0.75% Injectable Solution
- Where
- Denmark
- Volunteers
- 78 people
- Sponsor
- Nordsjaellands Hospital