Clinical trials: Operative Bleeding
Blood Loss, Surgical, Uterine Myoma
Effect of Rectal Misoprostol in Reducing Intra-operative Blood Loss During Myomectomy
A total of 200 women for elective abdominal myomectomy were randomly allocated into two groups. 100 women in experimental group were administered 400ug Misoprostol (2 tablets of Prosotec®) through the rectal route prior to…
- Trial name
- NCT05108597
- Testing
- Misoprostol
- Where
- Pakistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Pak Emirates Military Hospital
Blood Loss, Surgical, Blood Loss, Postoperative
Comparison Study of Oxytocin Versus Tranexamic Acid and Etamsylaye Versus Placebo(Saline)
Comparison Study Between Oxytocin Versus Tranexamic Acid and Ethamsylate Versus Normal Saline as Pre-operative Administration.
- Trial name
- NCT05273632
- Testing
- Oxytocin
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Egymedicalpedia
Post-operative Pain
Open Thyroid Surgery With Pillow Versus no Pillow for Better Post-operative Outcomes
Primary: To compare the post-operative pain in patients with neck extension and without neck extension. Secondary: To determine the benefit of neck exposure and peri-operative complications, which include duration of operation…
- Trial name
- NCT01620151
- Testing
- Extended neck with standard support or pillow
- Where
- 2 sites in Hong Kong
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Anticoagulant-induced Bleeding, Periodontal Diseases
Evaluation of the Intra- and Post- Operative Bleeding After Periodontal Debridement in Direct Anticoagulant Patients
Direct Oral Anticoagulants were recently approved for medical treatment of several condition such as, non valvular atrial fibrillation, deep venous thrombosis, and others, substituting sometimes the conventional oral…
- Trial name
- NOADB_db (NCT03124004)
- Testing
- periodontal debridement
- Where
- Italy
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Trieste
Misoprostol Allergy
Pre Versus Post-operative Misoprostol in Reducing Blood Loss After Cesarean Section
Cesarean section is the most common performed major surgical interventions among women all over the world.Cesarean section has many serious complications, including primary postpartum hemorrhage (PPH).
- Trial name
- NCT05928871
- Testing
- Misoprostol 200mcg Tab, Misoprostol Pill
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cairo University
Shoulder Arthroscopy, Operative Bleeding
The Effect of Tranexamic Acid (TXA) on Visualization During Shoulder Arthroscopy
Tranexamic acid has seen an increase in use over the past decade in hip and knee arthroplasty as well as spine surgery with more recent use seen in total shoulder arthroplasty (TSA).
- Conditions
- Shoulder Arthroscopy, Operative Bleeding, Postoperative Pain
- Trial name
- NCT04610164
- Testing
- Tranexamic acid
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Abdomen Hernia
The Effects of Post-Operative Interventions on Surgical Site Occurrences in AWR
Randomized controlled trial to compare SSO's in abdominal wall reconstruction patients using Prevena, Prineo, and traditional incisional dressings.
- Trial name
- NCT04906408
- Testing
- Prevena, Prineo, Traditional
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ohio State University
the Influence of Intra- vs Extra-abdominal Removal of Placenta, Duration of Operation
Extra-abdominal Removal of Placenta During CS
During cesarean section, it is important to provide hemostasis as well as to decrease the amount of hemorrhagic fluid and fibrin in the abdominal cavity.
- Conditions
- the Influence of Intra- vs Extra-abdominal Removal of Placenta, Duration of Operation, the Amount of Aspirated Fluid During the Operation, Difference Between Pre- and Post-operative CBC
- Trial name
- NCT02101450
- Testing
- Extra-abdominal removal of the placenta
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Near East University, Turkey
Acute Blood Loss Anemia, Postoperative Pain
Effect of Non-Dissection of the Inferior Rectus Sheath on Intraoperative Blood Loss
The purpose of this study is to evaluate the effect of non-dissecting the inferior rectus sheath during primary cesarean delivery on post-operative hemoglobin and post-operative pain control as measured by VAS score and opioid…
- Conditions
- Acute Blood Loss Anemia, Postoperative Pain, Pregnancy
- Trial name
- NCT02762773
- Testing
- non-dissection of inferior rectus sheath, control
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Coronary Artery Disease
Heparin Dose and Post Operative Bleeding in Cardiopulmonary Bypass Patients
Blood is anticoagulated using a drug named heparin during open-heart surgery to allow it to safely pass through the heart-lung machine which pumps the blood throughout the body during the surgery.
- Trial name
- NCT01574105
- Where
- 2 sites in Canada
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Surgical Blood Loss
Assessment of Hematologic Parameters Before and After Bimaxillary Orthognathic Surgery
The purpose of the present study was to compare some hematologic parameters and operation time in patients who underwent esthetic bimaxillary surgery under hypotensive anesthesia.
- Trial name
- NCT02364765
- Testing
- Remifentanil
- Where
- Brazil
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Edema, Ecchymosis; Eyelid
The Effect of Local Tranexamic Acid on Post-operative Edema and Ecchymosis in Eyelid Surgery
Tranexamic acid (TXA) is a synthetic inhibitor of plasminogen lysine receptor that has used to reduce intra-operative bleeding in a number of clinical scenarios.
- Trial name
- NCT04951128
- Testing
- Tranexamic acid injection, Local anesthetic control
- Where
- 4 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Consultants in Ophthalmic and Facial Plastics Surgery
Intraoperative Bleeding, Post-operative Bleeding
Study to Compare the Addition of Floseal to Our Standard of Care to Control Post Operative Bleeding in TKR
The purpose of this study is to compare Floseal to our standard of care (SOC) to decrease intraoperative and immediate post-operative bleeding.
- Trial name
- NCT01891461
- Testing
- Floseal
- Where
- Canada
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Abnormal Uterine Bleeding
Comparison Efficiency of Oral Etoricoxib Versus Intravenous Fentanyl on Post Operative Pain in Curettage Under TIVA
Comparison of the efficiency of oral Etoricoxib versus intravenous Fentanyl on post operative Pain in curettage under TIVA: A randomized controlled trial
- Trial name
- NCT03697733
- Testing
- fractional curettage
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Hysterotomy Closure
Study to Compare Suture Material in Closure of Uterine Incision in Cesarian Section
Prospective single blinded trial comparing standard synthetic suture material to a synthetic barbed suture in closure of uterine incision, during Cesarean section procedures.
- Trial name
- Stratafix (NCT02517710)
- Testing
- Stratafix synthetic barbed suture
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Evangelical Community Hospital, Lewisburg, PA
Postpartum Hemorrhage, Pain
Do Elastic Abdominal Binders Reduce Post Operative Pain and Blood Loss?
This is a pilot study investigating the use of abdominal binders after cesarean sections. The researchers are testing whether elastic abdominal binders improve postoperative pain control and reduce postoperative blood loss.
- Trial name
- NCT01786330
- Testing
- Procare abdominal binder, Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zachary Kuhlmann, DO
Anticoagulant-induced Bleeding, Dental Diseases
Intra- and Post- Operative Bleeding After Simple Dental Extraction in Direct Oral Anticoagulant Therapy
Direct Oral Anticoagulants were recently approved for medical treatment of several condition such as, non valvular atrial fibrillation, deep venous thrombosis, and others, substituting sometimes the conventional oral…
- Trial name
- NOADB (NCT03124030)
- Testing
- simple dental extraction
- Where
- Italy
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Trieste
Prostate Hyperplasia
The Effect of Pre-operative Use of Finasteride Versus Cyproterone Acetate on Blood Loss With Transurethral Resection of Prostate
Perioperative bleeding is the most common complication related to transurethral resection of prostate, the aim of the study is to compare the effect of pre-operative use of finasteride versus Cyproterone acetate on blood loss…
- Trial name
- NCT04848181
- Testing
- cyproterone acetate, finasteride, no treatment received
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Benha University
Blood Loss, Surgical
Arista Hemostatic Powder for Total Knee Post Operative Outcomes Study
To examine in Arista hemostatic powder results in less post-total knee arthroplasty blood loss, hematoma formation, and improved range of motion when compared to patients who did not receive the product.
- Trial name
- NCT05522153
- Testing
- Arista
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Virtua Health, Inc.
Operative Hemorrhage
Intrauterine Use of FloSeal: Is it Safe and Useful?
When having certain types of outpatient surgery inside the uterine cavity some women experience heavy bleeding. The only method presently available for controlling such bleeding, short of removing the uterus, involves the…
- Trial name
- NCT01746628
- Testing
- Hysterectomy with FloSeal
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- David L Zisow MD LLC