Clinical trials: Ophthalmic Disorders
Age Related Macular Degeneration, Macular Degeneration
Treatment of Age-related Macular Degeneration by Fetal Retinal Pigment Epithelial Cells Transplantation
Early Phase I Study of the Safety and Preliminary Efficacy of Human Fetal Retinal Pigment Epithelial(fRPE) Cells Subretinal Transplantation in Age-Related Macular Degeneration(AMD) Patients
- Conditions
- Age Related Macular Degeneration, Macular Degeneration, AMD
- Trial name
- NCT02868424
- Testing
- fRPE cells
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Myopia
Wearability of and Myopia Progression With ZEISS MyoCare Spectacle Lenses
This is a clinical trial evaluating the wearability and effectiveness of three types of ZEISS spectacle lenses in controlling myopia progression.
- Trial name
- NCT07021560
- Testing
- ZEISS MyoCare spectacle lenses, ZEISS SV RX SPH 1.5, ZEISS Clearview
- Where
- Vietnam
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- ZEISS Vision Care
Single-nucleotide Polymorphism (SNP) for Glaucoma
Investigation of Genetic Disease Marker Associated With Korean Glaucoma Patients
A single-nucleotide polymorphism (SNP) analysis of DNA obtained from peripheral blood of the glaucoma patients and the normal control will be performed to find genetic marker for primary open angle glaucoma.
- Trial name
- NCT01025024
- Testing
- SNP analysis of the DNA
- Where
- South Korea
- Volunteers
- 1,224 people, healthy volunteers welcome
- Sponsor
- Chungnam National University
Myopia, Amblyopia
Myopia Control With Three Lever Irradiance of PBM Therapy in Children and Adults
Photobiomodulation therapy, that is, Low-level red-light technology provides a new and innovative myopia control approach. This strategy enables relatively high energies of light to be delivered at much shorter durations of…
- Conditions
- Myopia, Amblyopia, Refractive Error - Myopia Axial, Ametropia
- Trial name
- MCPT (NCT05957458)
- Testing
- Airdoc device of red light for Myopia
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Beijing Airdoc Technology Co., Ltd.
Safety, Tolerability and Pharmacokinetic Profile in Healthy Volunteers, Choroidal Neovascularization
Safety, Tolerability and Pharmacokinetic Profile of SYL1801 Eye Drops
Study of the safety, tolerability and pharmacokinetic profile of different doses of SYL1801 eye drops in healthy volunteers.
- Trial name
- NCT04782271
- Testing
- SYL18001 sodium Low dose q.d, SYL18001 sodium Middle dose q.d, SYL18001 sodium High dose q.d
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Sylentis, S.A.
Retinal Hemorrhage, Bilateral, Retinal Hemorrhage, Left Eye
Retinal Imaging Study of Children That Might be at Risk of Having Retinal Hemorrhages
This is a clinical trial in which we will learn about the retinal findings in three clinical groups of children, who might be at risk of having retinal hemorrhages (RH).
- Conditions
- Retinal Hemorrhage, Bilateral, Retinal Hemorrhage, Left Eye, Retinal Hemorrhage, Right Eye
- Trial name
- RISC (NCT05576285)
- Testing
- ophthalmoscopy and fundus photography through dilated pupills
- Where
- Sweden
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Mixed Astigmatism
Study of the MEL 80 Excimer Laser Using LASIK in the Treatment of Mixed Astigmatism
The purpose of this study is to determine whether the MEL 80 Excimer Laser is effective in the treatment of mixed astigmatism up to 6.0 D, when used as part of the Laser In Situ Keratomileusis (LASIK) procedure.
- Trial name
- NCT00761826
- Testing
- MEL 80 Mixed Astigmatism Treatment
- Where
- 5 sites in United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Glaucoma
Spaeth/Richman Contrast Sensitivity Test
The Spaeth-Richman Contrast Sensitivity (SPARCS) test is a new method of assessing contrast sensitivity. The test, another way to measure vision, is performed on any standard computer with internet access.
- Trial name
- SPARCS (NCT01300949)
- Testing
- Spaeth/Richman Contrast Sensitivity Test, Pelli-Robson Contrast Sensitivity Chart
- Where
- United States
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- Wills Eye
Keratoconus
Customized Contact Lenses
The overall goal of this project is to improve the visual quality of individuals who have abnormal corneal conditions that alter the shape of their cornea (eg. keratoconus).
- Trial name
- NCT05134909
- Testing
- Customized contact lens
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Houston
Dry Eye Disease (DED)
A Study Evaluating the Efficacy and Safety of RCI001 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye
The objective of this study is to evaluate the safety and efficacy of 0.25% RCI001 Ophthalmic Solution twice a day (BID) and four times a day (QID) compared to placebo (vehicle) in the treatment of the signs and symptoms of dry…
- Trial name
- NCT07068958
- Testing
- 0.25% RCI001 Ophthalmic Solution
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- ORA, Inc.
Dry Eye
Comparison of Tolerability and Clinical Performance of Two Emulsion-type Artificial Tears
The purpose of this study is to evaluate the performance between two emulsion-type artificial tears.
- Trial name
- NCT01335126
- Testing
- Emulsion type artificial tear
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hom, Milton M., OD, FAAO
Blood Coagulation Disorders
The Effect of Voltaren-ophtha 0.1% Eye Drops on INR Levels (International Normalized Ratio) in Patients Taking Warfarin
A prospective study intended to examine the effect of topical Voltaren-Ophtha 0.1% eye drops after cataract surgery on INR levels (international normalized ratio) in patients taking warfarin.
- Trial name
- NCT02782338
- Testing
- Voltaren ophtha 0.1%
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Dry Eyes
Validating the Diagnostic Accuracy of Mediview 2.0 Software as an Image Analysis Tool of Meibomian Glands
Non-contact meibography is a useful tool in assessing the health of meibomian glands in patients. Instead of using normal light in contact meibography, non-contact meibography utilises infra-red (IR) light.
- Trial name
- NCT01991132
- Testing
- MediView 2.0 software
- Where
- Singapore
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Asthenopia, Contact Lenses
Connecting Contact Lenses and Digital Technology
This study seeks to address whether or not different types of daily disposable soft contact lenses may be a beneficial option for patients complaining of eye strain and visual discomfort while using digital devices.
- Conditions
- Asthenopia, Contact Lenses, Ocular Accommodation, Convergence, Excess
- Trial name
- NCT02921087
- Testing
- Test Daily Disposable Soft Contact Lenses, Control Daily Disposable Soft Contact Lenses
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry
Obtaining OCT (Optical Coherence Tomography) Images
Self-Monitoring OCT
The purpose of this research study is to test participants ability to obtain OCT images of the eyes using an OCT device that is comparable to FDA-approved OCT devices on the market, without the help of an eye technician.
- Trial name
- NCT07584798
- Testing
- Self-administered OCT imaging system, Technician-acquired OCT imaging
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Eye Movement Disorder, Cognitive Dysfunction
Eye Movement and Cognitive Dysfunction
There is association between eye movement disorder and cognitive dysfunction. Therefore, utilizing eye movement and screening for cognitive dysfunction is feasible.
- Trial name
- EMCD (NCT04236375)
- Where
- China
- Volunteers
- 1,539 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Visual Disorder
A Clinical Trial to Evaluate Investigational Silicone Hydrogel Contact Lenses Worn Continuously for One Week
This study is a prospective, randomized, double-masked, bilateral, dispensing, parallel-group clinical trial design. All subjects will participate in a 2-week daily disposable contact lens adaptation period prior to being…
- Trial name
- NCT02543528
- Testing
- Investigational Lens 1, Investigational Lens 2, Investigational Lens 3
- Where
- India
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Zhaoqing Myopia Study
Myopia is a common cause of vision loss, being particularly prevalent in children in East and Southeast Asia. The investigators will assess prevalence and incidence of myopia, identify digital biomarkers associated with myopia…
- Trial name
- NCT04219228
- Testing
- Ophthalmic examinations, Wearable devices
- Where
- 2 sites in China
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Glaucoma, Rubeosis Iridis
Intraocular Bevacizumab (Avastin) for Rubeosis Iridis
Bevacizumab (Avastin®, Roche, Rio de Janeiro, Brazil) is an anti-VEGF recombinant humanized monoclonal IgG1 antibody used to treat colorectal cancers.
- Trial name
- NCT00557232
- Testing
- bevacizumab
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Instituto de Olhos de Goiania
Subject With Primary Open-angle Glaucoma (POAG)
A Prospective Evaluation of Open-Angle Glaucoma Subjects on Two Topical Hypotensive Medications Treated With One Suprachoroidal Stent
The purpose of this study is to assess the efficacy and safety of one iStent supra stent in the reduction of intraocular pressure associated with primary open-angle glaucoma.
- Trial name
- NCT01252914
- Testing
- iStent Supra Stent
- Where
- Armenia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Glaukos Corporation
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