Clinical trials: Ophthalmic Surgery
Glaucoma, Open-Angle
A Post-market Study Of Use Of The OMNI® Surgical System In Open Angle Glaucoma
To prospectively compare the clinical effect of the OMNI surgical system in eyes with Open Angle Glaucoma.
- Trial name
- NCT04616573
- Testing
- OMNI® Surgical System, iStent inject
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- Sight Sciences, Inc.
Cataract
Evaluation of Performance of New IFIS Sleeve
A silicone sleeve will be used on the hydrodissection needle to avoid that the iris can prolaps through the gap between needle and incision wound.
- Trial name
- NCT06067360
- Testing
- IFIS sleeve
- Volunteers
- 20 people
- Sponsor
- Medicel AG
Cataract
Evaluation of the BunnyLens TR Intraocular Lens
With age, a human crystalline lens opacifies (cataract) disabling the eye in generating a clear, well contrasted image. The only therapeutic solution to this problem is surgical replacement of the crystalline lens with an…
- Trial name
- NCT01659801
- Testing
- BunnyLens TR
- Volunteers
- 25 people
- Sponsor
- Hanita Lenses
Endophthalmitis
OTX-14-002: Device Exposure Registry
The objective of the study is to collect post-approval data relative to the incidence of endophthalmitis for cataract surgery patients treated with the FDA-approved ReSure Sealant when used by a broad group of physicians under…
- Trial name
- NCT02309736
- Testing
- ReSure Sealant
- Sponsor
- Ocular Therapeutix, Inc.
Ocular Inflammation
Loteprednol Etabonate Ophthalmic Ointment vs. Vehicle in the Treatment of Inflammation Following Cataract Surgery
To evaluate the clinical safety and efficacy of Loteprednol Etabonate Ophthalmic Ointment, 0.5% vs. vehicle for the treatment of inflammation following cataract surgery
- Trial name
- NCT00645671
- Testing
- 0.5% Loteprednol Etabonate Ophthalmic Ointment, Vehicle of Loteprednol Etabonate Ophthalmic Ointment
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Astigmatism
LASIK Surgery With a New Laser for the Treatment of Myopia Without Astigmatism
The AQUARIUZ ablation laser is a solid-state laser and has been CE approved for corneal surgery since March 2020 for the treatment of short- and longsightedness with and without astigmatism.
- Trial name
- AQUARIUZ2020 (NCT04794023)
- Testing
- Corneal Ablation
- Where
- Switzerland
- Volunteers
- 27 people
- Sponsor
- Ziemer Ophthalmic Systems AG
Open-angle Glaucoma
Safety and Efficacy of the GTS400 Stent in Conjunction With Cataract
To evaluate the safety and efficacy of the Glaukos Trabecular Micro-Bypass Stent Model GTS400 in conjunction with cataract surgery, compared to cataract surgery only, in subjects with mild to moderate open angle glaucoma.
- Trial name
- NCT00721968
- Testing
- Glaucoma Stent Surgery (GTS400 Stent), cataract surgery alone
- Volunteers
- 62 people
- Sponsor
- Glaukos Corporation
Post Surgical Ocular Inflammation
A Study of TRS01 in Participants With Post-surgical Ocular Inflammation
The objective of this study is to evaluate the safety and preliminary efficacy of TRS01 eye drops as compared to placebo on participants with ocular inflammation after cataract surgery.
- Trial name
- NCT04222725
- Testing
- TRS01 eye drops
- Where
- 5 sites in United States
- Volunteers
- 37 people
- Sponsor
- Tarsier Pharma
Open-angle Glaucoma (OAG)
5-Year Postoperative Outcomes of Patients Who Completed the CREST Study
This study is designed to collect clinical data at 3, 4, and 5 years postoperatively for participants who completed the CREST Study without having secondary IOP-lowering surgery in the study eye(s).
- Trial name
- CREST-XT (NCT07480343)
- Testing
- CycloPen Micro-Interventional Cyclodialysis System, CycloPen Micro-Interventional Cyclodialysis System Post Cataract
- Where
- 10 sites in United States
- Volunteers
- 250 people
- Sponsor
- Iantrek, Inc.
Cataract
Long-term (3 Months) Safety of Femtosecond-laser Assisted Cataract Surgery
This clinical study is a prospective, post-market-clinical-follow-up study to investigate the long-term (3 months) safety of femtosecond laser assisted cataract surgery as a study follow-up extension to the Study #1304 titled as…
- Trial name
- NCT02023437
- Testing
- Femtosecond laser cataract surgery, Manual cataract surgery
- Where
- 2 sites in Czechia, India
- Volunteers
- 132 people
- Sponsor
- Technolas Perfect Vision GmbH
Glaucoma
Cataract Surgery vs Cataract Surgery With ECPL for Treatment of Plateau Iris Configuration or Syndrome
The purpose of this study is to assess and compare the mechanical angle opening in patients with angle closure due to a plateau iris configuration (elevated iris) using phacoemulsification combined with endoscopic cycloplasty…
- Trial name
- NCT02049333
- Testing
- Phacoemulsification, Endoscopic Cycloplasty (ECPL)
- Where
- 2 sites in Canada
- Volunteers
- 26 people
- Sponsor
- Credit Valley EyeCare
Primary Open Angle Glaucoma (POAG), Cataract
Study of an Implantable Device for Lowering Intraocular Pressure in Glaucoma Patients Undergoing Cataract Surgery
The purpose of this study is to evaluate the safety and efficacy of the CyPass Implant for lowering intraocular pressure (IOP) in patients with glaucoma who undergo cataract surgery.
- Trial name
- COMPASS (NCT01085357)
- Testing
- Cataract Surgery, CyPass Micro-Stent
- Volunteers
- 897 people
- Sponsor
- Transcend Medical, Inc.
Aphakia, Cataract
Clinical Study to Evaluate the Safety and Effectiveness of the RxSight Light Adjustable Lens (LAL) in Subjects With Prior Corneal Refractive Surgery
The primary objective of this study is to evaluate, for the visual correction of aphakia, the safety and effectiveness of the RxSight Light Adjustable Lens (LAL) and Light Delivery Device (LDD) to reduce postoperative refractive…
- Trial name
- NCT03660865
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD), Control IOL
- Where
- 6 sites in United States
- Volunteers
- 105 people
- Sponsor
- RxSight, Inc.
Postoperative Ocular Inflammation, Postoperative Ocular Pain
A Phase 3 Study Evaluating the Safety and Efficacy of TRIESENCE® (Injectable Suspension) for the Treatment of Ocular Inflammation and Pain After Ophthalmic Surgery
This study is designed to evaluate the safety and efficacy of TRIESENCE® (triamcinolone acetonide injectable suspension) in patients undergoing ophthalmic procedures.
- Trial name
- NCT07832552
- Testing
- TRIESENCE (triamcinolone acetonide injectable suspension)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Harrow Inc
Ocular Inflammation and Pain
Efficacy and Safety of APP13007 for Treatment of Inflammation and Pain After Cataract Surgery
This Phase 3 study will evaluate APP13007 in comparison to the matching vehicle placebo in a randomized, parallel-group, double-masked fashion.
- Trial name
- NCT04739709
- Testing
- APP13007, 0.05%
- Where
- 35 sites in United States, Puerto Rico
- Volunteers
- 378 people
- Sponsor
- Formosa Pharmaceuticals, Inc.
Glaucoma, Primary Open Angle
Excimer Laser Trabeculostomy Glaucoma Treatment Study
Evaluation of the safety and effectiveness of the ELIOS System procedure to reduce intraocular pressure (IOP) in adult subjects with mild to moderate primary open-angle glaucoma (POAG) undergoing cataract surgery
- Trial name
- ELTGTS (NCT04899063)
- Testing
- ELIOS Procedure
- Where
- 20 sites in United States
- Volunteers
- 318 people
- Sponsor
- Elios Vision, Inc.
Cataracts Infantile
Clobetasol Propionate Ophthalmic Nanoemulsion, 0.05% in the Treatment of Inflammation After Cataract Surgery in Pediatric Population
Multicenter, randomized, evaluator-blinded clinical trial compared to Prednisolone acetate, 1% in the treatment of inflammation and pain after cataract surgery in pediatric population.
- Trial name
- CLOSE-3 (NCT05724446)
- Testing
- Clobetasol Propionate, Prednisolone acetate ophthalmic suspension, 1%
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Salvat
Cataracts
Comparison of Centurion® Vision System With Balanced Tip and the Infiniti® Vision System With the Mini Flared Kelman (MFK) Tip During Cataract Extraction Surgery of Hard Lenses
The purpose of this study is to demonstrate that the Centurion® Vision System (CVS) used with the 45° Balanced Tip will result in less Cumulative Dissipated Energy (CDE) than the lnfiniti® Vision System (IVS) used with the 45°…
- Trial name
- NCT02502526
- Testing
- Centurion® Vision System, 45° Balanced Tip, Centurion® Vision System, 45° MFK Tip, lnfiniti® Vision System, 45° MFK Tip
- Volunteers
- 231 people
- Sponsor
- Alcon Research
Dry Eye Disease
Study of Application of Pulse Electrical Stimulation Around Eye in Dry Eye Disease Patients Who Are Scheduled for Laser Epithelial Keratomileusis (LASEK) Surgery
This study aims to evaluate the efficacy and safety of applying pulse Electrical Stimulation around eye after laser keratoplasty (LASEK) in patients with dry eye syndrome.
- Trial name
- NCT06120348
- Testing
- Charge-Balanced, Symmetric Nerve Stimulation
- Where
- 6 sites in South Korea
- Volunteers
- 178 people
- Sponsor
- Nu Eyne Co., Ltd.
Blepharitis, Dry Eye Syndrome
Treatment of Meibomian Gland Dysfunction Prior to Cataract Surgery
The purpose of this pilot feasibility study is to assess whether treating meibomian gland dysfunction (MGD) prior to cataract surgery helps promote meibomian gland function, visual quality and ocular comfort after cataract…
- Trial name
- NCT01808560
- Testing
- LipiFlow Pre-Treatment, LipiFlow Post-treatment
- Where
- 7 sites in United States
- Volunteers
- 34 people
- Sponsor
- TearScience, Inc.