Clinical trials: Ophthalmic Surgery
Dry Eye
Role of Postoperative Lubrication in Cataract Surgery
Cataract and dry eye are two conditions occurring frequently in the elderly. Several reports suggested a deterioration of dry eye after cataract surgery, causing a significant impact on patients' postoperative satisfaction as…
- Trial name
- NCT06555224
- Testing
- Systane Hydration MDPF eye drops
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Cataracts
Comparing Optical Coherence Tomography (OCT) and Visual Acuity Outcomes in Subjects Undergoing Cataract Surgery, Who Receive Xibrom Ophthalmic Solution and Standard Presurgical Care vs. Xibrom Ophthalmic Solution Plus Prednisolone Acetate 1% and Standard Presurgical Care
To compare the efficacy of twice-daily topical bromfenac (Xibrom) ophthalmic solution alone versus twice-daily topical Xibrom with prednisolone acetate 1% three-times daily on visual acuity and OCT measurements.
- Trial name
- NCT00698724
- Testing
- Xibrom, and Optive, Xibrom and Pred Forte
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bp Consulting, Inc
Dry Eye Disease, Cataract
Hyaluronic Acid-containing Artificial Tears in Post-cataract Surgery Dry Eye Disease
To compare the effects of hydroxypropyl guar (HPG)/hyaluronic acid (HA)- and carboxymethylcellulose (CMC)/HA-based lubricant eye drops on subjective and objective outcomes in dry eye disease (DED) patients after cataract surgery.
- Trial name
- NCT06221345
- Testing
- Systane HYDRATION® Preservative-Free Lubricant Eye Drops, Optive Fusion® Lubricant Eye Drops (Unit Dose)
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- Chang Gung Memorial Hospital
Pterygium
Comparison Between Sutureless and Glue Free Versus Sutured Limbal Conjunctival Autograft in Primary Pterygium Surgery
Pterygium is a common ocular pathology facing ophthalmologists that has varied surgical management techniques and high rate of post-operative recurrence.
- Trial name
- NCT02009072
- Testing
- Sutureless and glue free limbal conjunctival autograft, Sutured limbal conjunctival autograft
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Shaaban Elwan
Cataracts, Inflammation
Difluprednate Pediatric Study for the Treatment of Inflammation Post-Cataract Surgery
The primary objective of this study was to compare the safety and efficacy of Durezol™ compared to Pred Forte™ for the treatment of inflammation following cataract surgery in a pediatric population 0 to 3 years of age.
- Trial name
- NCT01124045
- Testing
- Difluprednate ophthalmic emulsion, 0.05%, Prednisolone acetate ophthalmic suspension, 1.0%
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Alcon Research
Eye Cyclorotation Degree, Pupil Shift
Evaluation of Position-induced Cyclorotation Between Wavefront Measurement and Refractive Surgery by the Iris Registration Method
Cyclorotation of eyes may be affected by motion and orientation of the head and body. An automated alignment method with the technique of iris recognition was used to assess the amount and orientation of position-induced…
- Trial name
- NCT00943163
- Where
- Taiwan
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cataract, Inflammation
Indomethacin Eyedrops Compared With Ketorolac Eyedrops for Ocular Inflammation Following Cataract Surgery
This study is being conducted to show that indomethacin is at least as effective as ketorolac for the prevention of ocular inflammation following cataract surgery.
- Trial name
- NCT00904904
- Testing
- Indomethacin ophthalmic solution, Ketorolac Ophthalmic Solution
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract, Anxiety
Evaluation of the Effectiveness of Stress Ball Practice During Cataract Surgery
Cataract surgery is one of the most commonly performed and reliable surgeries among eye diseases. While cataract surgeries were performed under general or local anesthesia in previous years, they are now performed topically.
- Conditions
- Cataract, Anxiety, Pain
- Trial name
- NCT05847114
- Testing
- Stres ball
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ege University
Glaucoma, Open-Angle
A Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical System
The purpose of this study is to evaluate the long-term safety and effectiveness of the OMNI® Surgical System in subjects who were treated under protocol #06213
- Trial name
- NCT05044793
- Testing
- OMNI® Surgical System
- Where
- 4 sites in United States
- Volunteers
- 70 people
- Sponsor
- Sight Sciences, Inc.
Operative Time, Fatigue
3D-HD Optic Systems Influence Surgical Performance
Randomized controlled trial in which two different laparoscopic systems: standard 2D and Olympus VISERA Elite II 3D will be compared in terms of laparoscopic skills, length of surgery, intraoperative complications and surgeon's…
- Conditions
- Operative Time, Fatigue, Surgery--Complications
- Trial name
- NCT04185116
- Testing
- 3D Optic System (Olympus VISERA Elite II 3D)
- Where
- Spain
- Volunteers
- 102 people
- Sponsor
- Hospital Clinic of Barcelona
Cataracts
Endothelial Cell Loss After Cataract Surgery
The purpose of this study is to compare two cataract surgical technique variations for removing the nucleus of the lens (central part of the lens) in terms of damage to the inner layer of the cornea which is called the…
- Trial name
- NCT00932191
- Testing
- Standard phacoemulsification, Reduced ultrasound phacoemulsification
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of California, San Francisco
Cataract
Anterior Chamber Depth Variability Between Two Lenses With Different Materials
Compare the change of the Anterior chamber depth (ACD) variability between the Clareon and the AcrySof Intraocular lens (IOL) after implantation over 6 months.
- Trial name
- NCT03751215
- Testing
- Cataract surgery
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Aphakia, Cataract
Comparison of Aspheric Toric & Non-toric Aphakic Intraocular Lenses
The purpose of this multi-center clinical trial is to determine the safety and efficacy of the HSO Toric IOLs for the correction of aphakia and reduction of pre-existing refractive astigmatism.
- Trial name
- COAST (NCT01268540)
- Testing
- FY-60AD, NHT15, NHT30, & NHT53
- Where
- 6 sites in United States
- Volunteers
- 235 people
- Sponsor
- Hoya Surgical Optics, Inc.
Cataract
Subfoveal Choroidal Thickness After Surgery for Age-related Cataracts
To compare the effects of femtosecond laser-assisted cataract surgery (FLACS) and conventional phacoemulsification surgery (CPS) on subfoveal choroidal thickness (SFCT) in age-related cataracts.
- Trial name
- NCT02895074
- Testing
- Femtosecond laser-assisted cataract surgery, Conventional phacoemulsification cataract surgery, Tropicamide
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Sun Yat-sen University
Macular Hole
Outcomes of Macular Hole Surgery With Inverted Flap With vs Without Post op Posturing With SF6 in Macular Hole More Than 400 Micrometres
This study evaluated the outcomes of surgery for large full-thickness macular holes measuring more than 400 micrometres using the inverted internal limiting membrane flap technique with sulphur hexafluoride (SF6) gas tamponade.
- Trial name
- NCT07787390
- Testing
- Macular Hole Surgery With Inverted Internal Limiting Membrane Flap and SF6 Gas Tamponade, Face-Down Postoperative Positioning, No Face-Down Postoperative Positioning
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Lahore General Hospital
Nuclear Sclerotic Cataract
Comparison of Scheimpflug Photos of the Crystalline Lens in Patients Who Have Undergone Vitrectomy Surgery and Controls
Progression of nuclear sclerotic cataract after pars plana vitrectomy has been recognized for many years The mechanism for the rapid progression of nuclear sclerotic cataract remains unclear.
- Trial name
- NCT00406263
- Testing
- Scheimpflug crystalline lens photographs
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Barnes Retina Institute
Cataract
Evaluate the Safety of DEXYCU for the Treatment of Inflammation Following Ocular Surgery for Childhood Cataract
A Phase 3/4, Prospective, Randomized, Active Treatment-Controlled, Parallel-Design, Multicenter Study to Evaluate the Safety of DEXYCUfor the Treatment of Inflammation Following Ocular Surgery for Childhood Cataract
- Trial name
- NCT05191706
- Testing
- Dexamethasone, Prednisolone Acetate Ophthalmic
- Where
- 9 sites in United States
- Volunteers
- 17 people
- Sponsor
- EyePoint Pharmaceuticals, Inc.
Blepharoptosis
Astigmatic Changes Secondary to Eyelid Surgeries
Eyelid surgeries change the lid position over the cornea. Previous surgeries evaluated astigmatic corneal changes in children undergoing ptosis repair.
- Trial name
- NCT01968174
- Where
- 3 sites in Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Retinal Detachment
Evaluation of Neuroprotective Effect of Minocycline
This process appears as a incredible and progressive event that will not stop till reattachment of RPE and neurosensory retina happened .
- Trial name
- minocyclin &RD (NCT01297816)
- Testing
- Minocycline
- Where
- Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences
Cataract, Presbyopia
MULTICENTER, DOUBLE-ARM, PATIENT AND ASSESSOR-MASKED, PROSPECTIVE, RANDOMIZED CLINICAL TRIAL TO COMPARE VISUAL PERFORMANCE OF NEGATIVE AND NEUTRAL ASPHERIC MONOFOCAL INTRAOCULAR LENSES
The purpose of this study is to compare the binocular distance, intermediate, and near visual acuity and patient reported outcomes of the Johnson \&Johnson Eyhance and Bausch \& Lomb enVista IOLs.
- Trial name
- NCT07385014
- Testing
- Neutral Aspheric Monofocal IOL, Negative Aspheric Monofocal IOL
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Milton S. Hershey Medical Center
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