Clinical trials: Ophthalmic Surgery
Macular Holes
Comparison of Two Intraocular Gas Injection Techniques in Macula Hole Surgery
To undertake a prospective randomized clinical trial of vitrectomy and gas tamponade to treat macular hole, utilizing a small amount of undiluted C3F8 (perfluoropropane) versus a large amount of diluted C3F8 versus a small amount…
- Trial name
- NCT04527848
- Testing
- small amount of undiluted C3F8
- Where
- Brazil
- Volunteers
- 48 people
- Sponsor
- Universidade Federal de Pernambuco
Cataract
Impact of Ophthalmic Surgeon Experience on Early Postoperative Central Corneal Thickness
To assess the impact of surgeon experience on early postoperative central corneal thickness (CCT) in eyes that have undergone phacoemulsification-based cataract surgery.
- Trial name
- CHICA (NCT03685825)
- Volunteers
- 160 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Post-surgical Cystoid Macular Edema (PSCME)
Treatment of Post-surgical Cystoid Macular Edema With Topical Steroids Trial (TEMPEST-1)
The purpose of this study is to compare the change in visual acuity of patients with post surgical cystoid macular edema who will be treated with two different regimens.
- Trial name
- TEMPEST (NCT01769352)
- Testing
- PredA + Kelac
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Johns Hopkins University
Primary Congenital Glaucoma, Goniotomy
Goniotomy in Primary Congenital Glaucoma
Brief Summary This is a multicenter cohort study designed to evaluate and compare the efficacy and safety of different surgical extents of goniotomy (GT) - specifically 120°, 240°, and 360° - in the treatment of Primary…
- Trial name
- NCT07550868
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Sun Yat-sen University
Dry Eye Disease, Meibomian Gland Dysfunction
Preoperative iLux on Cataract Surgery Derived Dry Eye Disease Due to Meibomian Gland Dysfunction
This prospective study will investigate the effect of pre-operative Systane iLux system administration in treated cataract induced dry eye disease.
- Conditions
- Dry Eye Disease, Meibomian Gland Dysfunction, Cataract Senile, Dry Eye Syndromes
- Trial name
- NCT06483750
- Testing
- Systane iLux Treatment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- George Washington University
Corneal Transplant Rejection
Risk Factors for Human Corneal Graft Failure : a Monocentric Retrospective Observational Cohort
Keratoplasty is one of the most common grafts and penetrating keratoplasty is still the technique most used in the world, ahead of lamellar grafts, and is estimated to represent 70% of the total.
- Trial name
- NCT04791696
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Glaucoma, Open-angle
The Effectiveness of YAG Iridotomy in Preventing Peripheral Anterior Synechia After CLASS in Primary Open Angle Glaucoma
To investigate the effectiveness of YAG laser iridotomy in preventing peripheral anterior synechia after CO2 Laser-Assisted Sclerectomy Surgery and the long-term effect of reducing intraocular pressure
- Trial name
- NCT04912362
- Testing
- YAG iridotomy
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Keratoconus
Prevelance of Keratoconus
Keratoconus is a degenerative disease entity characterized by conical shape ectasia of the cornea. progressive conical deformation of the cornea leads to substantial astigmatism.
- Trial name
- NCT04092426
- Testing
- opthalmologic examination
- Volunteers
- 300 people
- Sponsor
- Assiut University
Endotracheal Intubation During Surgery, Optic Nerve Sheath Diameter
Oropharyngeal Vs Intravenous Lidocaine Effects on Optic Nerve Sheath Diameter After Intubation
This study aims to evaluate the effects of pre-intubation oropharyngeal topical lidocaine on optic nerve sheath diameter (ONSD) post-endotracheal intubation.
- Trial name
- NCT06874179
- Testing
- Optic nerve sheath diameter measurement 0, optic nerve sheath diameter measurement 1, optic nerve sheath diameter measurement 2
- Where
- Turkey (Türkiye)
- Volunteers
- 190 people
- Sponsor
- Ankara City Hospital Bilkent
Retinal Detachment
Using Triamcinolone Acetonide to Reduce Pain After Scleral Buckle Surgery
PURPOSE: Scleral buckle surgery is a widely used ophthalmic surgery for the correction of rhegmatogenous retinal detachment. Studies suggest that eye pain is a common and underestimated occurrence after scleral buckle surgery…
- Trial name
- NCT04701593
- Testing
- Triamcinolone Acetonide 40mg/mL
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Virginia Polytechnic Institute and State University
Surrgical Induced Astigmatism
Surgically Induced Astigmatism of Temporal Versus Nasal Clear Corneal Phacoemulsification
To compare the short-term astigmatic outcomes of phacoemulsification cataract surgery and intraocular lens implantation using temporal versus nasal clear corneal incisions.
- Trial name
- NCT00521833
- Testing
- phacoemulsification and intraocular lens implantation
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Cataract
Mapracorat Ophthalmic Suspension for the Treatment of Ocular Inflammation Following Cataract Surgery
The objective of this clinical study is to compare the safety and efficacy of Mapracorat Ophthalmic Suspension, 3% to vehicle for the treatment of postoperative inflammation and pain following cataract surgery.
- Trial name
- NCT01230125
- Testing
- Mapracorat, Vehicle
- Where
- United States
- Volunteers
- 311 people
- Sponsor
- Bausch & Lomb Incorporated
Glaucoma
Effectiveness of a Procedure for Previously Failed Glaucoma Surgery
Transconjunctival mitomycin-C in needle bleb revision may be an effective procedure to treat cases with a previously failed trabeculectomy. We will investigate approximately 100 consecutive cases with follow up of up to 9 years.
- Trial name
- NCT00347789
- Testing
- Glaucoma surgery- Bleb revision
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Glaucoma Research & Education Group
Glaucoma
The Results of Ahmed Valve Operations
Glaucoma drainage devices are usually placed in the superior quadrants. The superotemporal quadrant is usually the site of choice.
- Trial name
- NCT00193960
- Testing
- 1) Intraocular pressure 2) visual acuity
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University Health Network, Toronto
Prone Position, Blood Volume
The Effect of High vs. Low Fluid Volume on Ocular Parameters in Prone Spine Surgery
The purpose of this trial is to compare the effect of different fluid volume infusion on ocular parameters in patients undergoing spine surgery in prone position.
- Conditions
- Prone Position, Blood Volume, Intraocular Pressure
- Trial name
- NCT03890510
- Testing
- Ringer's Lactate solution, Spine surgery under general Anesthesia in the prone position
- Where
- China
- Volunteers
- 97 people
- Sponsor
- Huashan Hospital
Coronary Artery Disease, Acute Cerebrovascular Accident
Incidence of Acute Cerebrovascular Events Using Either Minimized or Standard Cardiopulmonary Bypass Circuit
The prospective, randomized, two centre study investigates acute cerebrovascular events during extracorporal circulation and the early post operative outcome when using either the minimized cardiopulmonary bypass circuit…
- Conditions
- Coronary Artery Disease, Acute Cerebrovascular Accident, Intracranial Embolism, Embolism, Air
- Trial name
- ROCsafeTM (NCT00862160)
- Testing
- ROCsafeTM
- Where
- 2 sites in Germany
- Volunteers
- 64 people
- Sponsor
- Hannover Medical School
Cataract Surgery
Reducing Patient Waiting Time for Cataract Surgery
The purpose of this study is to examine how coordination between hospital departments affects patient flow between the free ward (B1), paid ward (C1) and the operating theatre (OT) for cataract surgeries at a tertiary eye care…
- Trial name
- NCT07484659
- Testing
- Standard Operating Procedures (SOPs)
- Where
- India
- Volunteers
- 360 people
- Sponsor
- Seva Canada Society
Anxiety
Cranial Electro Therapy Stimulation in Reducing Perioperative Anxiety
Cranial electro stimulation (CES) provides safe, adequate, side-effect free sedation without excessive drowsiness in preoperative settings.
- Trial name
- NCT00928772
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- University of Oklahoma
Strabismus
Lees Screen in Concomitant Strabismus
Preoperative and postoperative Lees screen was done after concomitant horizontal strabismus surgery to detect any limitation in the field of operated muscle
- Trial name
- NCT04213053
- Testing
- strabismus surgery
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Minia University
Intraocular Pressure
Effect of Sevoflurane Concentration on Intraocular Pressure in Surgical Children With Healthy Eyes
One important goal in anesthetic management during ocular surgery is to provide adequate control of intraocular pressure (IOP). An increase in IOP may be catastrophic in patients with glaucoma or a penetrating open-eye injury.
- Trial name
- NCT01248689
- Testing
- concentration profile 1, concentration profile 2, concentration profile 3
- Where
- Israel
- Volunteers
- 21 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
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