Clinical trials: Ophthalmic Surgery
Nursing Care, Intensive Care Unit ICU
Sleep Quality in Surgical Intensive Care
It is thought that transferring low-cost and easily applicable interventions that can be used to control environmental stressors such as noise and light that negatively affect sleep quality, especially in intensive care…
- Conditions
- Nursing Care, Intensive Care Unit ICU, Sleep Quality
- Trial name
- NCT06973252
- Testing
- Eye masks
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Aydin Adnan Menderes University
Cornea
Analysis of Topographic Corneal Parameters
The Pentacam HR system (OCULUS) has been suggested to be one of the most sensitive instruments for corneal examination before corneal refractive surgery
- Trial name
- NCT06220578
- Testing
- Oculus pentacam HR
- Where
- Egypt
- Volunteers
- 2,694 people
- Sponsor
- Minia University
Esotropia, Exotropia
Comparison of Two Treatments for Strabismus Correction: Botulinum Toxin A Associated to Surgery and Surgery Alone
Two different treatments were given to large angle horizontal strabismus (eso and exotropia) adult patients who agree to participate of the study. Inform consents were required for participants.
- Trial name
- NCT01460355
- Testing
- Botulinum Toxin Type A, saline solution
- Where
- Brazil
- Volunteers
- 23 people
- Sponsor
- University of Campinas, Brazil
Optic Nerve Sheath Diameter
Changes of Optic Nerve Sheath Diameter Between Obese and Non-obese Patients Undergoing Laparoscopic Gynecological Surgery
This study aims to compare the change of optic nerve sheath diameter in obese and non-obese patients undergoing laparoscopic gynecological surgery in a steep Trendelenburg position.
- Trial name
- NCT04427085
- Testing
- Ultrasound assessment of optic nerve sheath diameter
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- SMG-SNU Boramae Medical Center
Cataract, Anxiety
Personalized Music for Anxiety During Cataract Surgery
This randomized controlled trial evaluated the effect of a personalized music intervention on anxiety and pain in patients undergoing cataract surgery under local anesthesia.
- Conditions
- Cataract, Anxiety, Pain
- Trial name
- NCT07767643
- Testing
- Structured Personalized Music Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ege University
Glaucoma, Glaucoma, Open Angle
SOLX Titanium Sapphire Laser for Trabeculoplasty
Use of the Titanium Sapphire laser for laser trabeculoplasty to reduce intraocular pressure in patients with poorly controlled intraocular pressure on maximally tolerated medical therapy or prior failed laser trabeculoplasty.
- Trial name
- NCT00145535
- Testing
- SOLX Titanium Sapphire Laser (TiSaLT), Argon Laser Trabeculoplasty (ALT)
- Where
- 10 sites in United States, Canada and 2 more
- Volunteers
- 120 people
- Sponsor
- SOLX, Inc.
Primary Angle-Closure Glaucoma
Predicting the Risk of Partial Ciliary Block After Cataract and Goniosynechialysis Surgery in Primary Angle-Closure Disease
Primary angle-closure disease (PACD) is a major cause of vision loss, often treated with a combined surgery that removes the eye's natural lens (cataract surgery) and physically opens the eye's drainage system…
- Trial name
- PCB-Risk (NCT07549438)
- Volunteers
- 1,150 people
- Sponsor
- Peking University People's Hospital
Macular Holes
Position Related Changes in Macular Hole Morphology Before and After Surgery
Macular hole is a full thickness retinal defect in the very centre of the retina that gives the sharpest vision. The condition causes a substantial deterioration of visual acuity, and operative measures are necessary in order to…
- Trial name
- NCT04676217
- Testing
- Postoperative positioning advice
- Where
- 2 sites in Norway
- Volunteers
- 40 people
- Sponsor
- Helse Stavanger HF
Cataract
In Clinic Optometrist Insertion of Dextenza Prior to Cataract Surgery
To evaluate the clinical outcomes with optometrist pre-surgical insertion of DEXTENZA in the clinical office setting in patients undergoing same-day cataract surgery compared to standard of care steroid therapy.
- Trial name
- Prepare (NCT05023304)
- Testing
- Dextenza 0.4Mg Ophthalmic Insert, Topical prednisolone acetate
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vance Thompson Vision
Dry Eye, Cataract
Lubricating Eye Drops After Routine Cataract Surgery
Patient satisfaction and dry symptoms in patients undergoing routine uncomplicated cataract surgery in NHS patients treated with prophylactic phosphate-free, preservative-free lubricant eye drops (0.3% cross linked sodium…
- Trial name
- NCT04465071
- Testing
- AEONTM Repair and AEONTM Protect Plus lubricating eye drops
- Where
- United Kingdom
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Primary Open Angle Glaucoma, Glaucoma, Open Angle, Pseudo-exfoliative
Safety and Efficacy Trial to Evaluate the Hydrus(TM) Implant in Subjects Undergoing Cataract Surgery.
The objective of this study is to demonstrate the ability of the Hydrus Implant to lower intraocular pressure in glaucoma patients undergoing cataract surgery.
- Conditions
- Primary Open Angle Glaucoma, Glaucoma, Open Angle, Pseudo-exfoliative, Cataract Unilateral Pending Extraction
- Trial name
- Hydrus II (NCT01818115)
- Testing
- Hydrus Implant, IOL placement
- Where
- 7 sites in Germany, Italy and 2 more
- Volunteers
- 100 people
- Sponsor
- Ivantis, Inc.
Glaucoma, Cataract
Combined Phacotube vs Phacotrabeculectomy:A Randomized Controlled Trial
The aim of this study is to compare the effectiveness and safety of combined phacoemulsification, posterior chamber intraocular lens implantation , trabeculectomy (phacotrabeculectomy) with phacoemulsification, intraocular lens…
- Trial name
- NCT00273221
- Testing
- Glaucoma Implant Surgery, trabeculectomy, phacoemulsification
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- National University Hospital, Singapore
Intraocular Melanoma, Melanoma (Skin)
Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed By Surgery
RATIONALE: Vaccines may make the body build an immune response to kill tumor cells. PURPOSE: This phase II trial is studying how well vaccine therapy works in treating patients with stage III or stage IV melanoma that cannot be…
- Trial name
- NCT00089206
- Testing
- incomplete Freund's adjuvant, multi-epitope melanoma peptide vaccine, sargramostim
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Virginia
Cataracts, Cataract Surgery
Endothelial Cell Loss and Induced Astigmatism After Wound-directed and Wound-assisted IOL Injection
The purpose of this study is to determine if there is any difference in astigmatism (eye surface curvature) or corneal endothelial cell density (the inner cell lining of the eye surface) after two different methods for inserting…
- Trial name
- NCT01250964
- Testing
- Lens insertion during cataract surgery
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of North Carolina, Chapel Hill
Coronary Artery Disease, Sleep Disorder
The Effect of Eye Mask Applied on Patients Undergoing Coronary Artery Bypass Graft Surgery
Introduction: Coronary Artery Bypass Graft (CABG) performed with open heart surgery technique is a successful operation in the treatment of cardiovascular diseases.
- Conditions
- Coronary Artery Disease, Sleep Disorder, Pain, Postoperative
- Trial name
- NCT06010498
- Testing
- eye mask, standart care
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Diabetic Macular Edema
Vitrectomy Retinal Oxygenation
Vitrectomy is the common treatment for patients with macular edema secondary to epiretinal membrane. Recently, in eyes with diabetic macular edema or persistent macular edema following retinal vein occlusion, vitrectomy will be…
- Trial name
- NCT01510691
- Where
- Austria
- Sponsor
- Stefan Sacu
Glaucoma
Lucentis Versus Mitomycin C During Glaucoma Surgery
Does a new add on (or adjunctive) therapy used in glaucoma surgery improve the success of trabeculectomy? Ranibizumab may offer benefit similar to mitomycin C in preventing epi-scleral fibrosis while avoiding the well known…
- Trial name
- NCT00626782
- Testing
- Ranibizumab, Mitomycin (MMC)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Wills Eye
Endophthalmitis, Cataract Surgery
Prophylaxis Prior to Cataract Surgery Conjunctival Flora and Optimal Ocular Sterilization Technique Prior to Cataract Surgery
The purpose of this study is to evaluate the conjunctival flora prior to cataract or vitrectomy surgery comparing mupirocin ointment applied to the conjunctiva along with standard ocular sterilization vs.
- Conditions
- Endophthalmitis, Cataract Surgery, Prophylaxis
- Trial name
- NCT00406913
- Testing
- mupirocin ointment, SOC sterilization
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Chicago
Evisceration; Traumatic, Eye
Quality Of Life After Eye Surgical Removal
Studies have shown that health-related quality of life (HRQOL) was worse among patients who underwent surgical eye removal compared to the general population in Denmark.
- Trial name
- QOLAE (NCT05397743)
- Testing
- Quality of Life
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Surgery
Intraoperative Non-invasive Eye Movement Monitoring
For procedures involving proximity to the nerves responsible for eye movement, the need to monitor eye movement exists. The current solution is to place needles in the muscles surrounding the eye.
- Trial name
- NCT03046615
- Testing
- EEG Electrode Patch, Standard Needles
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Mayo Clinic
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