Clinical trials: Ophthalmic Surgery
Supratentorial Neoplasms, Anesthesia, General
Effect of PEEP on Subdural Pressure, Optic Nerve Sheath Diameter, Lung Compliance and Brain Perfusion Pressure
We aim to determine the level of intraoperative PEEP that optimizes lung compliance without causing a rise in subdural pressure and if we can utilize optic nerve sheath diameter measurement as an indicator for ICP while…
- Conditions
- Supratentorial Neoplasms, Anesthesia, General, Optic Nerve
- Trial name
- NCT04316208
- Testing
- PEEP variations
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University
Cataract Surgery
Comparison of Two Phacoemulsification Systems in Cataract Surgery (UNITY VCS vs. Centurion)
This prospective, randomized, contralateral (crossover) study compares the ultrasound efficiency and early postoperative outcomes (Day 1 and Day 7) of two phacoemulsification platforms - the UNITY® VCS system with 4D Phaco and…
- Trial name
- COMPASS (NCT07756385)
- Testing
- UNITY VCS SYSTEM ®, CENTURION VISION SYSTEM ®
- Where
- Croatia
- Volunteers
- 30 people
- Sponsor
- University Hospital Sveti Duh
Inflammation, Cataract Surgery
Clinical Efficacy of the Drug Ster® Compared With Predfort® in Control of Postoperative Inflammation in Cataract Surgery
Is the primary objective of this investigation to compare the clinical efficacy of the drug test - Ster ® (prednisolone 1% ophthalmic suspension - Union Chemicals) in the comparator - Fort ® Pred (prednisolone 1% ophthalmic…
- Trial name
- NCT01227876
- Testing
- Ster, Pred Fort
- Where
- Brazil
- Volunteers
- 106 people
- Sponsor
- Azidus Brasil
Laparoscopic Gynecologic Surgery
Effects of Sevoflurane and Propofol on Optic Nerve Sheath Diameter During Laparoscopic Gynecologic Surgery
Intracranial pressure（ICP) increases during laparoscopic gynecologic surgery increase (ICP) and may alter optic nerve sheath diameter(ONSD).This study measures ONSD in different team because sevoflurane and propofol have…
- Trial name
- NCT03498235
- Testing
- Sevoflurane, Propofol
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Obstetrics & Gynecology Hospital of Fudan University
Cataract
Clinical Outcomes of Patients Bilaterally Implanted With the TECNIS® Symfony or TECNIS® Symfony Toric Extended Range of Vision IOL
In With increased patients' demand for a spectacle-free lifestyle and technological advancements, cataract surgery with multifocal intraocular lens (IOL) implantation has become an effective solution for correcting presbyopia in…
- Trial name
- NCT03997890
- Testing
- Cataract surgery with binocular implantation of either Symfony (ZXR00) or Symfony toric (ZXT) IOLs
- Where
- South Korea
- Volunteers
- 96 people
- Sponsor
- Yonsei University
Open Angle Glaucoma
A Comparison of Two Ab Interno Procedures in the Treatment of Glaucoma in Patients Undergoing Cataract Extraction
The purpose of this study is to compare the safety and efficacy of goniotomy performed with a novel ophthalmic knife compared to trabecular bypass stent implantation in mild to moderate glaucoma subjects who are also undergoing…
- Trial name
- NCT02784249
- Testing
- Goniotomy, Trabecular Micro-Bypass Stent, Cataract Extraction
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- New World Medical, Inc.
Cataract Surgery, Intraocular Lens Position
The Effect of Capsulotomy Size on Effective Lens Position in Robotic Laser Cataract Surgery
The goal of this clinical trial is to learn whether the size of the opening made during laser-assisted cataract surgery affects where the artificial lens sits in the eye and the glasses prescription after surgery.
- Conditions
- Cataract Surgery, Intraocular Lens Position, Refractive Outcomes After Cataract Surgery, Cataract
- Trial name
- PRECISE (NCT07856849)
- Testing
- Femtosecond Laser Capsulotomy - Small Size (4.6 mm), Femtosecond Laser Capsulotomy - Large Size (5.6 mm)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Twin Cities Eye Consultants
Orthopedic Surgery, Nursing Care
Effect of Earplugs and Eye Masks Used After Orthopedic Surgery on Comfort and Quality of Recovery
This research will be conducted as a randomized controlled trial to determine the effects of earplugs and eye masks used after orthopedic surgery on comfort and quality of recovery.
- Conditions
- Orthopedic Surgery, Nursing Care, Quality of Recovery 40, Comfort
- Trial name
- NCT06986408
- Testing
- Earplugs and Eye Masks
- Volunteers
- 60 people
- Sponsor
- Ankara Yildirim Beyazıt University
Pterygium
A Novel Technique for the Removal of Pterygiums
The aim of this study is to introduce a new surgical technique for the removal of pterygiums that entails the use of bipolar electrocautery to secure the graft, rather than sutures.
- Trial name
- NCT02321150
- Testing
- Cautery, Sutures
- Where
- Barbados
- Volunteers
- 50 people
- Sponsor
- The University of The West Indies
Post-Surgical Ocular Pain, Post-Surgical Ocular Inflammation
OTX-14-003: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Ocular Inflammation and Pain After Cataract Surgery
The objective of the study was to evaluate the safety and efficacy of OTX-DP (dexamethasone insert) 0.4 mg for intracanalicular use when placed in the canaliculus of the eyelid for the treatment of post-surgical inflammation and…
- Trial name
- NCT02089113
- Testing
- Dexamethasone
- Volunteers
- 241 people
- Sponsor
- Ocular Therapeutix, Inc.
Blindness
A Study to Evaluate the BrainPort Vision Device in Individuals Blinded by Traumatic Injury
The BrainPort V200 Device is a wearable, non-surgical, prosthetic device intended for people who are profoundly blind. The BrainPort V200 translates images captured by a digital camera into electro-tactile stimulation presented…
- Trial name
- NCT02393118
- Testing
- BrainPort V200 Device
- Where
- 3 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wicab
Glaucomas, Pterygium
Ologen(Oculusgen)-Glaucoma and Pterygium Historical Control Study in China Shanghai Sixth People's Hospital
The purpose of this study is to determine whether the ologen (OculusGen) Collagen Matrix are effective and safe to implant as an aid of glaucoma surgery and pterygium excision surgery.
- Trial name
- NCT00478790
- Testing
- ologen™ Collagen matrix implantation in glaucoma filtering surgery
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Pro Top & Mediking Company Limited
Glaucoma, Choroidal Effusions
Triamcinolone Injections for Persistent Choroidal Effusions Post Glaucoma Surgery
During glaucoma surgery, a new opening is created that allows fluid to drain out of the eye, bypassing the clogged drainage channels that are malfunctioning in patients with glaucoma.
- Trial name
- TRICEPS (NCT02917564)
- Testing
- Triamcinolone Acetonide 1 ml of 40 mg/mL suspension
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Sunnybrook Health Sciences Centre
Cataract
Comparison of Two Fragmentation Modalities in Femtosecond Laser-assisted Cataract Surgery
Femtosecond laser-assisted cataract surgery consists in nuclear lens fragmentation, followed by ultrasound phacoemulsification of nuclear lens, which is then removed.
- Trial name
- SLICES (NCT02898909)
- Testing
- nuclear lens fragmentation in 8 pieces, nuclear lens fragmentation in 16 pieces
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Visual Correction, Refractive Surgery
Outcomes of Cataract & Refractive Procedures
The primary objective of the database is to retrospectively analyse the visual and refractive outcomes of cataract and refractive procedures in order to continuously assess outcomes and also compare outcomes between the different…
- Conditions
- Visual Correction, Refractive Surgery, Cataract Surgery
- Trial name
- NCT07481487
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- Vision Care Collective Limited
Myopia, Astigmatism
SMILE Surgery in One Eye Compared to Ray Tracing-guided LASIK Surgery in the Fellow Eye
Participants will undergo LASIK surgery in one eye using ray tracing guided technology in one eye and LASIK surgery in the other eye using wavefront guided technology.
- Trial name
- NCT07721714
- Testing
- Ray tracing guided LASIK surgery
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Stanford University
Corneal Wavefront Aberration, Refractive Errors
Factors Influencing Subjective Visual Quality in Human Eyes
To assess subjective visual symptoms using the QoV questionnaire, measure pupil size using the Atongmu Pupillometer, measure wavefront aberrations using the OPD-Scan III Aberrometer, and measure/calculate the effective optical…
- Trial name
- NCT07518316
- Testing
- Corneal Refractive Surgery
- Volunteers
- 300 people
- Sponsor
- Tianjin Eye Hospital
Myopia, Astigmatism
Quality of Vision and Quality of Life With LASIK
The investigators are administering a validated questionnaire looking at patient reported quality of life and quality of vision after LASIK surgery
- Conditions
- Myopia, Astigmatism, Quality of Lifte
- Trial name
- NCT02161263
- Testing
- Patient Quality of Life andVision after LASIK Surgery
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Edward E. Manche
Enucleated; Eye, Evisceration; Operation Wound
Retrobulbar Block Versus Ketamine Infusion for Post-enucleation Analgesia
This study compares the efficacy and safety of two techniques, retrobulbar block versus intra-operative ketamine infusion, for control of post-operative pain occurring in patients undergoing ocular enucleation or evisceration…
- Conditions
- Enucleated; Eye, Evisceration; Operation Wound, Pain, Postoperative
- Trial name
- NCT03507426
- Testing
- Retrobulbar block, Ketamine
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Nazmy Edward Seif
Cataract
Nepafenac Opthalmic Suspension 0.1% Compared to Acular LS for Treatment of Inflammation After Cataract Surgery
The purpose of this study is to compare the effectiveness of Nepafenac Ophthalmic Suspension, 0.1% eye drops to Acular LS eye drops, used before and after cataract surgery, for treating inflammation in the eye.
- Trial name
- NCT00333255
- Testing
- Nepafenac Ophthalmic Suspension, 0.1%
- Where
- United States
- Volunteers
- 267 people
- Sponsor
- Alcon Research