Clinical trials: Ophthalmic Surgery
Cataract
Comparison of Clinical Outcomes After Cataract Surgery With and Without Capsular Tension Ring
This study was set up to identify clinical outcomes including a refractive shift or change in IOL calculation accuracy and optical quality after Ophtec® capsular tension ring in the eyes without zonular instability.
- Trial name
- NCT02183831
- Testing
- Insertion of the capsular tension ring
- Volunteers
- 52 people
- Sponsor
- Yonsei University
Myopia, High Myopia
Clinical Results of Small Incision Lenticule Extraction (SMILE) for the Correction of High Myopia
Small Incision Lenticule Extraction (SMILE) was introduced in 2011 using the VISUMAX femtosecond laser (Carl Zeiss Meditec, Jena, Germany). It is designed for correction of myopia and myopic astigmatism.
- Trial name
- NCT04110067
- Testing
- Small Incision Lenticule Extraction (SMILE) with Visumax (Carl Zeiss Meditec, Jena)
- Where
- Germany
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Suphi Taneri
Dry Eye
Efficacy of Low-Level Light Therapy in Reducing Dry Eye in Patients Undergoing Cataract Surgery
The goal of this clinical trial is to evaluate the effectiveness of Low Level Light Therapy (LLLT) in reducing the incidence or alleviating the severity of DED due to meibomian gland dysfunction in otherwise healthy patients…
- Trial name
- NCT05754437
- Testing
- Low Level Light Therapy
- Where
- Italy
- Volunteers
- 130 people
- Sponsor
- Azienda Ospedaliera Universitaria Mater Domini, Catanzaro
Cataract, Astigmatism
Toric Intraocular Lens Following Cataract Surgery
The objective of this clinical trial is to evaluate the safety and effectiveness of the Bausch + Lomb Toric Accommodating Posterior Chamber Silicone Intraocular Lens used to provide near, intermediate, and distance vision and a…
- Trial name
- NCT01140477
- Testing
- Toric Accommodating Lens, Accommodating Lens
- Where
- United States
- Volunteers
- 229 people
- Sponsor
- Bausch & Lomb Incorporated
Diabetic Retinopathy
Perfluorocarbon Perfused Vitrectomy and 3D Vitrectomy System in Advanced Diabetic Retinopathy
To investigate the feasibility and advantages of using perfluorocarbon liquid (PCL) perfusion to remove vitreous during suction-cutting vitrectomy using a dual, dynamic drive (3D)technology.
- Trial name
- NCT00407108
- Testing
- Vitrectomy
- Where
- Mexico
- Sponsor
- Asociación para Evitar la Ceguera en México
Myopia
Corneal Topography Asymmetry Indices Changes After Corneal Refractive Surgery
To evaluate the changes that occur in the corneal indices after corneal refractive surgery either PRK or LASIK.
- Trial name
- NCT04589091
- Testing
- Refractive surgery
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Dementia, Mild Cognitive Impairment
Evaluation of the Effect of Cataract Surgery on Cognitive Function in Very Elderly Patients
The study intends to measure the evolution over time of the cognitive capacity of patients undergoing cataract surgery in relation to the opaque lens removal surgery (cataract) in a population considered to be at risk of…
- Conditions
- Dementia, Mild Cognitive Impairment, Cataract Senile, Cataract
- Trial name
- NCT04047485
- Testing
- Visual Acuity, CAM (Confusion Assesment Method), CATQUEST 9-SF
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Modena and Reggio Emilia
Cataract, Healthy Eye
The Heidelberg Engineering ANTERION Anterior Segment Cornea and IOL Precision and Agreement Study
This is a prospective clinical study that will be conducted at one clinical site located in the United States to assess anterior segment parameters with the ANTERION
- Conditions
- Cataract, Healthy Eye, Cornea Abnormality, Post-Keratorefractive Surgery
- Trial name
- NCT04130490
- Testing
- ANTERION
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Heidelberg Engineering GmbH
Exotropia
Surgery for Large Angle Exotropia Two Muscles Versus Three Muscles
Comparison Between The Results Of Two Muscles Surgery And Three Muscles Surgery For The Treatment Of Large Angle Exotropia
- Trial name
- XT (NCT05643456)
- Testing
- surgery
- Where
- Egypt
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Cairo University
Lacrimal Duct Obstruction
A Comparative Study of Two Endoscopic Operations for Lacrimal Duct Obstruction
To compare the clinical effects between the silicone nasolacrimal intubation under nasoendoscopy and dacryocystorhinostomy on patients with lacrimal duct obstruction.
- Trial name
- ACSOTEOFLDO (NCT02636257)
- Testing
- Recessive Spherical Headed Silicone Intubation, Dacryocystorhinostomy
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Ocular Inflammation
PGE2 Levels in Patient Treated With NSAIDs
The aim of this study is to determine vitreous levels of nonsteroidal antinflammatory drugs (NSAIDs) and prostaglandinE2 (PGE2) in eyes scheduled for vitrectomy. All patients received the study drugs for 3 days before surgery.
- Trial name
- NCT03597867
- Testing
- Dicloftil, Nevanac, Indom
- Where
- Italy
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Trieste
Fuchs Endothelial Corneal Dystrophy
A Study to Investigate the Safety and Efficacy of K-321 Eye Drops After Simultaneous Cataract Surgery and Descemetorhexis in Participants With Fuchs Endothelial Corneal Dystrophy (FECD)
A study to assess the safety and efficacy of K-321 in participants with FECD after simultaneous cataract surgery and descemetorhexis.
- Trial name
- NCT05826353
- Testing
- Ripasudil
- Where
- 43 sites in United States, Canada and 4 more
- Volunteers
- 110 people
- Sponsor
- Kowa Research Institute, Inc.
Orbital Fractures, Enophthalmos
Correction of Enophthalmos and Orbital Volume Using Pre-bent Mesh Versus 3d Printed Onlay in Orbital Fracture Cases
this study evaluates the post-surgical correction of enophthalmos and orbital volume using 3D printed only versus pre-bent titanium mesh in blow-out fracture cases
- Conditions
- Orbital Fractures, Enophthalmos, Periorbital Fracture
- Trial name
- NCT04271137
- Testing
- 3D printed PEEK onlay, Pre-bent orbital mesh
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Retinal Detachment, Lens Diseases
Retinal Detachment After Lens Surgery in the Nearsighted
This study aims to study the incidence of retinal detachment in the nearsighted myopic after phakoemulsification lens surgery and use of posterior chamber foldable soft implants with a follow-up of 5 years and preliminary results…
- Conditions
- Retinal Detachment, Lens Diseases, Short-Sighted
- Trial name
- A09F0401 (NCT04072939)
- Testing
- Patients having had a lens surgery
- Volunteers
- 101 people
- Sponsor
- University Hospital, Bordeaux
Rhegmatogenous Retinal Detachment
Retinal Detachment - Demographic and Clinical Survey
Background: Rhegmatogenous retinal detachment is an ophthalmic emergency that, without surgical repair, often leads to blindness. The incidence is about 1/10000/year.
- Trial name
- NCT01845571
- Where
- Austria
- Volunteers
- 400 people
- Sponsor
- Medical University of Vienna
MCS vs ReLACS, Pain Perception Postoperatively First Eye vs Second Eye
A Comparison of Patient Perceptions Undergoing Manual Cataract Surgery (MCS) vs Refractive Laser-assisted Cataract Surgery (ReLACS) in First and Second Eyes
The focus of this study is to assess how pain can be mitigated for patients undergoing cataract surgery through the early application of anesthesia prior to the surgery as compared to the standard timing, and by using the ReLACS…
- Conditions
- MCS vs ReLACS, Pain Perception Postoperatively First Eye vs Second Eye, Early Anesthesia vs Standard Anesthesia
- Trial name
- NCT04623229
- Testing
- MCS, ReLACS Early, ReLACS Standard
- Where
- Canada
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Uptown Eye Specialists
Congenital Cataract
Aphakia Versus Pseudophakia in Children Under 2 Years Undergoing Bilateral Congenital Cataract Surgery
The purpose of this study is to document the safety and efficacy of primary IOL implantation in children below 2 years of age undergoing congenital cataract surgery.
- Trial name
- NCT01297153
- Testing
- Intraocular Lens (Acrysof IOL), No IOL
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Myopia, Astigmatism
An Outcomes Study Comparing the Intralase FS 60 to the Intralase iFS When Performing LASIK Surgery for Nearsightedness
The purpose of the study is to compare the results of LASIK surgery when using two versions of a femtosecond laser in patients with nearsightedness with and without astigmatism.
- Trial name
- NCT01365728
- Testing
- LASIK with the iFS femtosecond laser
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Stanford University
Diabetic Macular Edema, Cataract
Anti-VEGF Intravitreous Injections for Diabetic Macular Edema in Patients Undergoing Cataract Surgery
The investigators aim to evaluate how different timing of anti-VEGF intravitreous injections affect visual acuity (BCVA) in patients with diabetic macular edema who are undergoing cataract surgery; and to evaluate how different…
- Trial name
- Anti-VEGF (NCT04063358)
- Testing
- Lucentis
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Second Military Medical University
Cataract
ACRYSOF® ReSTOR® Aspheric +3.0 D Add Power Intraocular Lens (IOL)
Randomized, parallel group, subject masked, multi-center six (6) month follow-up study comparing ACRYSOF® ReSTOR® Aspheric +3.0 D Add Power IOL Model SN6AD1 implanted in both eyes to ACRYSOF® ReSTOR® Aspheric +4.0 D Add Power IOL…
- Trial name
- NCT00684138
- Testing
- ACRYSOF® ReSTOR® Aspheric +4.0 D Add Power Intraocular Lens, ACRYSOF® ReSTOR® Aspheric +3.0 D Add Power Intraocular Lens
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Alcon Research
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