Clinical trials: Ophthalmic Surgery
Cataract
Pseudophakic Anterior Chamber Depth Measurement in Second Eye Refinement Cataract Surgery
To study the effective lens position concept in second eye refinement (SER) cataract surgery, by relating inter-ocular symmetry of pseudophakic anterior chamber depth (pACD) measured in Pentacam and SER refractive outcomes.
- Trial name
- NCT02423668
- Testing
- 50% Partial adjustment, No adjustment, Full adjustment
- Volunteers
- 88 people
- Sponsor
- Centro Hospitalar do Baixo Vouga
Pupil Dilation Prior to Cataract Surgery In-patient, Pupil Dilation Prior to Cataract Surgery Out-patient
Preoperative Cataract Pupillary Dilation: Inpatient At The Ambulatory Surgery Center vs Outpatient Dilation Prior To Arrival At The Ambulatory Surgery Center
This study was done to compare efficacy, safety and efficiencies of various methods of pupil dilation prior to cataract surgery.
- Trial name
- NCT01169688
- Testing
- Pupil dilation with phenylephrine 10% vs cyclopentolate 2%
- Volunteers
- 50 people
- Sponsor
- Northwest Kansas Surgery Center
Cataract, Surgery
Evaluating a Dropless Postoperative Regimen After Cataract Surgery in a Vulnerable, County-hospital Population
The current postoperative cataract surgery eye drop regimen used at Zuckerberg San Francisco General Hospital (ZSFG) is a significant burden for its patient population, contributing to high rates of non-adherence and the…
- Conditions
- Cataract, Surgery, Compliance, Patient, Compliance, Medication
- Trial name
- NCT05157113
- Testing
- Dropless Regimen, Standard Regimen
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of California, San Francisco
Phacoemulsification, Cataract
Sedation Methods During Cataract Surgery
Background: Phacoemulsification is the most common surgical procedure performed in the United States and European Union and sedation is commonly used during phacoemulsification to help alleviate patient anxiety and prevent the…
- Trial name
- NCT03054103
- Testing
- Midazolam + Ketamine 10 MG/ML: 0.5 ML, Midazolam + Ketamine 10 MG/ML: 1 ML, Midazolam + Normal saline
- Volunteers
- 105 people
- Sponsor
- Wake Forest University Health Sciences
Glaucoma, Congenital, Surgical Treatment
Inverted T Trabeculectomy Primary Congenital Glaucoma
This study aims to evaluate the safety and efficacy of novel Inverted T trabeculectomy in Primary Congenital Glaucoma (PCG). It enrolled 50 eyes of 25 children with PCG.
- Trial name
- Inverte T trab (NCT06837610)
- Testing
- Inverted T trabeculectomy
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Benha University
Open-Angle Glaucoma
A Study of the Glaukos Trabecular Micro-bypass Stent in Open Angle Glaucoma Subjects 1 Stent Versus 2
The purpose of this study is to evaluate the safety and efficacy of the iStent trabecular micro-bypass stent in reducing intraocular pressure (IOP) in subjects with open-angle glaucoma.
- Trial name
- NCT00326079
- Testing
- Stent
- Where
- 7 sites in Austria, Germany and 2 more
- Volunteers
- 61 people
- Sponsor
- Glaukos Corporation
Cataract
Nepafenac Opthalmic Suspension 0.1% Compared to Acular LS for Treatment of Inflammation After Cataract Surgery
The purpose of this study is to compare the effectiveness of Nepafenac Ophthalmic Suspension, 0.1% eye drops to Acular LS eye drops, used before and after cataract surgery, for treating inflammation in the eye.
- Trial name
- NCT00333255
- Testing
- Nepafenac Ophthalmic Suspension, 0.1%
- Where
- United States
- Volunteers
- 267 people
- Sponsor
- Alcon Research
Agitation
Different Premedication in Pediatric Patients
The investigators studied the effects of intranasal dexmedetomidine compared with oral midazolam with different doses for premedication in children.
- Trial name
- NCT04266340
- Testing
- dexmedetomidine, midazolam, Saline
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Low Flow Anesthesia, Sevoflurane
Low Flow Anesthesia in Children Undergoing Strabismus Surgery
Emergence agitation (EA) involves restlessness, disorientation, excitation, non-purposeful movement, inconsolability, thrashing, and incoherence during early recovery from general anesthesia.
- Conditions
- Low Flow Anesthesia, Sevoflurane, Strabismus, Emergence Delirium
- Trial name
- LFA in child (NCT06560268)
- Testing
- Sevoflurane; In our study, the effects of sevoflurane in different FGFs administered in children undergoing strabismus surgery on EA and anesthetic agent consumption will be investigated.
- Volunteers
- 150 people
- Sponsor
- Cukurova University
Diabetic Retinopathy, Diabetic Cataract
Pars Plana Vitrectomy Combined With Phacoemulsification Cataract Surgery in Phakic Diabetes Retinopathy Patients
Pars plana vitrectomy (PPV) is one of the most widely used surgical therapies to proliferative diabetic retinopathy in the world.
- Trial name
- NCT04729023
- Testing
- Pars plana vitrectomy combined with cataract surgery., Pars plana vitrectomy with subsequent cataract surgery.
- Where
- China
- Volunteers
- 129 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Cataract
Sharp Health Companion App for Cataract Surgery Preparation and Recovery
This randomized controlled trial evaluated the effectiveness of the Sharp Health Companion App, a smartphone-based digital health tool, compared to standard printed instructions for supporting older adults undergoing cataract…
- Trial name
- NCT07028359
- Testing
- Printed Instructions with Phone Reminders, Sharp Health Companion App (CareKit)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Sharp HealthCare
Cataract
AI-Enhanced Consent for Cataract Surgery
This research focuses on enhancing the informed process for patients before undergoing cataract surgery. Currently, this process involves verbal discussions and written materials that may not fully address patients' understanding…
- Trial name
- NCT06528509
- Testing
- AI-Generated Informative Videos, Standard Written Information Brochures
- Where
- 2 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Hyperalgesia, Cataract Bilateral Nos
Gabapentin Pretreatment for Staged Bilateral Cataract Operations
To evaluate the effect of oral gabapentin premedication on hyperalgesia in elderly patients undergoing staged bilateral cataract operations under monitored anesthesia care
- Trial name
- NCT03826615
- Testing
- Gabapentin
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Seoul National University Hospital
Myopic Astigmatism
A Study to Investigate the Safety and Effectiveness of the Technolas® TENEO 317 Model 2 Excimer Laser for Laser In Situ Keratomileusis (LASIK) Surgery to Treat Myopia or Myopic Astigmatism
This will be a multicenter, prospective, open label, non-randomized, single arm study evaluating the safety and effectiveness of the Technolas® TENEO 317 Model 2 (version 1.28 US software) Excimer Laser when used in LASIK surgery…
- Trial name
- NCT07377474
- Testing
- TENEO 317 Model 2 (1.28 US) Excimer Laser
- Volunteers
- 32 people
- Sponsor
- Bausch & Lomb Incorporated
1mg Vs 3 mg of Granisetron
A COMPARATIVE STUDY BETWEEN 1MG AND 3 MG OF GRANISETRON IN THE PREVENTION OF POSTOPERATIVE NAUSEA AND VOMITING IN STRABISMUS OPHTHALMIC SURGERIES DURING GENERAL ANESTHESIA
Investigators aim to determine the optimal dose of granisetron in strabismus ophthalmic surgeries under general anesthesia to prevent postoperative nausea and vomiting
- Trial name
- NCT04918862
- Testing
- Granisetron
- Where
- Egypt
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pterygium
Efficacy of Autologous Fibrin Glue in Pterygium
Pterygium is wing-shaped, vascular, fleshy growth that originates on the conjuntiva and that can spread to the corneal limbus and beyond The surgical exeresis with autologous conjunctival autograft technique is the treatment of…
- Trial name
- NCT04151017
- Testing
- Autologous fibrin glue, Suture
- Where
- Brazil
- Volunteers
- 64 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Glaucoma, Ocular Hypertension
Safety and Efficacy of TimoD Sustained-Release Implant in Participants With Glaucoma or Ocular Hypertension Undergoing Cataract Surgery
The goal of this clinical trial is to test a new method to deliver an approved medicine called Timolol in the eye of participants with glaucoma or ocular hypertension and requiring cataract surgery.
- Trial name
- NCT07036510
- Testing
- TimoD implant, Injector system, Timolol eye drops 0.5%
- Where
- Panama
- Volunteers
- 42 people
- Sponsor
- EyeD Pharma
Cataract; Eye Disease
The Utility of a Novel Eye Shield With Reusable Adhesive Anchors for Post-operative Care After Ophthalmic Surgery
The purpose of this research study is to evaluate the efficacy, patient preference, and utility of a novel eye shield that utilizes a different adhesive mechanism in comparison to the current standard of care.
- Trial name
- NCT05957796
- Testing
- Novel "Snaps" Eye Shield, Standard Alcon Eye Shield
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Augusta University
Extraocular Extension Melanoma, Metastatic Intraocular Melanoma
Axitinib in Treating Patients With Melanoma That is Metastatic or Cannot Be Removed by Surgery
This phase II trial studies how well axitinib works in treating patients with melanoma that has spread to other places in the body or cannot be removed by surgery.
- Conditions
- Extraocular Extension Melanoma, Metastatic Intraocular Melanoma, Recurrent Intraocular Melanoma, Recurrent Melanoma
- Trial name
- NCT01533948
- Testing
- axitinib, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Roswell Park Cancer Institute
Cataract
Occyo Tele-ophthalmology Study
The prospective, (observer) blinded clinical trial at the University Hospital for Ophthalmology includes patients routinely scheduled for cataract surgery at the Medical University of Innsbruck.
- Trial name
- OTS (NCT06681350)
- Testing
- Ocular surface imaging
- Where
- Austria
- Volunteers
- 365 people
- Sponsor
- Medical University Innsbruck
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