Clinical trials: Ophthalmic Surgery
Inflammation, Pain
Loteprednol Ophthalmic Gel for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery
The objective of this study is to evaluate the safety and efficacy of loteprednol etabonate ophthalmic gel
- Conditions
- Inflammation, Pain, Cataract
- Trial name
- NCT01996839
- Testing
- Loteprednol Etabonate Gel (BID), Loteprednol Etabonate Gel (TID), Vehicle (BID)
- Where
- United States
- Volunteers
- 514 people
- Sponsor
- Bausch & Lomb Incorporated
Graves Disease
Does Potassium Iodide (SSKI) Reduce Vascularity in Graves' Thyroidectomy?
The purpose of this research is to find out if SSKI (Potassium Iodide) reduces vascularity (the number and concentration of blood vessels) and improves how well patients do after surgery for removal of their whole thyroid gland…
- Trial name
- NCT04080505
- Testing
- SSKI- Potassium Iodide
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Columbia University
Cataract, Pain
LE Gel for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery
Loteprednol Etabonate Ophthalmic Gel, (BID and TID) versus Vehicle Group for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery.
- Conditions
- Cataract, Pain, Ocular Inflammation
- Trial name
- NCT02786901
- Testing
- Loteprednol Etabonate Ophthalmic Gel dosed TID, Loteprednol Etabonate Ophthalmic Gel dosed BID, Vehicle Gel
- Where
- 6 sites in United States
- Volunteers
- 600 people
- Sponsor
- Bausch & Lomb Incorporated
Non-Proliferative Diabetic Retinopathy, Cataract
Nepafenac Once Daily for Macular Edema - Study 2
The purpose of this study is to demonstrate superiority of Nepafenac Ophthalmic Suspension, 0.3% dosed once daily relative to Nepafenac Vehicle based upon clinical outcomes among diabetic participants following cataract surgery.
- Trial name
- NCT01872611
- Testing
- Nepafenac Ophthalmic Suspension, 0.3%, Vehicle, Prednisolone acetate
- Volunteers
- 819 people
- Sponsor
- Alcon Research
Cataract
Cataract Surgery: Femto LDV Z8 Versus Conventional
The aim of the study is to demonstrate the performance and safety of the Femtosecond laser-assisted anterior capsulotomy and lens fragmentation on human eyes using the FEMTO LDV Z8 compared to conventional technique in cataract…
- Trial name
- COMFORT (NCT02351271)
- Testing
- Femto LDV Z8, Manual capsulorhexis&lens fragmentation
- Volunteers
- 130 people
- Sponsor
- Ziemer Ophthalmic Systems AG
Glaucoma, Optic Neuropathy
Use of Bevacizumab in Trabeculectomy Surgery
When a patient with glaucoma who has a pressure that is too high and causing damage to their vision, despite receiving the maximum amount of medication that can be tolerated, the decision is made to have glaucoma surgery.
- Conditions
- Glaucoma, Optic Neuropathy, Fibrosis
- Trial name
- NCT01166594
- Testing
- Bevacizumab, Control
- Where
- Canada
- Volunteers
- 59 people
- Sponsor
- Sunnybrook Health Sciences Centre
Blepharoptosis, Lagophthalmos
Magnetic Correction of Eye Lid Paralysis
Objective 1: Determine the safety and feasibility of externally mounted magnets for extended management of chronic eyelid movement disorders by measuring visual acuity and corneal and skin integrity and comfort over 8 weeks of…
- Conditions
- Blepharoptosis, Lagophthalmos, Facial Paralysis
- Trial name
- NCT02988856
- Testing
- Magnetic lid system
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Kevin Houston
Operative Incision
70 vs 110 Degree Side-cut Angles in Femtosecond LASIK
The purpose of this study is to compare 70 and 110 degree side-cut angles on the same patient undergoing Femtosecond Laser-assisted in Situ Keratomileusis (FS-LASIK).
- Trial name
- NCT03122535
- Testing
- FS-LASIK 70 degree side-cut angle, FS-LASIK 110 degree side-cut angle
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- University of Utah
Cataracts
DisCoVisc Comparative Evaluation
A comparison of the ability of DisCoVisc to that of other Opthalmic Viscosurgical Devices (OVDs) (DuoVisc®, BioVisc®, Healon5®, or Amvisc PLUS) regarding endothelial protection and anterior chamber space maintenance during…
- Trial name
- NCT00732225
- Testing
- DisCoVisc, DuoVisc, BioVisc
- Where
- United States
- Volunteers
- 173 people
- Sponsor
- Alcon Research
Persistent Corneal Epithelial Defects
Efficacy and Safety Study of Nexagon for Persistent Corneal Epithelial Defects
The purpose of this study is to evaluate the efficacy and safety of Nexagon® in subjects with persistent corneal epithelial defects (PED) resulting from corneal epithelial debridement during diabetic vitrectomy surgery, HSV…
- Trial name
- NTX-PED-001 (NCT01165450)
- Testing
- Nexagon, Vehicle only
- Volunteers
- 2 people
- Sponsor
- University of California, San Francisco
Ocular Inflammation
Efficacy and Safety Study of IBI-10090 in Cataract Surgery Patients
This study will test the efficacy and safety of IBI-10090 in the treatment of ocular inflammation after cataract surgery.
- Trial name
- NCT01214174
- Testing
- IBI-10090
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- ICON Bioscience Inc
Refractive Errors
Measurement of Refractive SE Following Implantation of LS313 MF30 IOL
This Study determines the most precise method for measuring post-operative refraction following implantation of the asymmetric multifocal LS-313 MF30 comparing the results of Refraction of the different Autorefractor Keratometers…
- Trial name
- NCT03292614
- Testing
- Measurements of the postoperative refraction
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Dietrich-Bonhoeffer-Klinikum
Cataract, Floppy Iris Syndrome
Intraoperative Floppy Iris Syndrome
An assessment of the surgical performance of DisCoVisc compared to Healon5 during cataract surgery with intraocular lens implantation where miotic/small pupils or intraoperative Floppy Iris Syndrome exists.
- Trial name
- NCT00711347
- Testing
- DisCoVisc, Healon5
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Alcon Research
Corneal Dystrophy, Epithelial Basement Membrane
Optimizing the Ocular Surface Prior to Cataract Surgery
Prospective study to evaluate the efficacy of using self-retained cryopreserved amniotic membrane after debridement in treating Epithelial Base Membrane Dystrophy (EBMD) to optimize the ocular surface integrity and intraocular…
- Trial name
- NCT02766907
- Testing
- cryopreserved amniotic membrane
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- BioTissue Holdings, Inc
Pseudophakia, Inflammation
Clinical Outcomes and Evaluation of Lotemax 0.5% in Treatment of Ocular Inflammation Associated With Cataract Surgery
Investigate the intraocular pressure(pressure inside the eye) of patients who are treated with Lotemax after undergoing cataract surgery.
- Trial name
- NCT01344226
- Testing
- loteprednol 0.5% ophthalmic solution
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Toyos Clinic
Inflammation Associated With Cataract Surgery
Efficacy and Safety of IBI-10090 in Ocular Surgery Patients
This study will test the efficacy and safety of IBI-10090 in the treatment of ocular inflammation after ocular surgery.
- Trial name
- NCT01606735
- Testing
- IBI-10090
- Where
- 2 sites in United States
- Volunteers
- 172 people
- Sponsor
- ICON Bioscience Inc
Cataract and IOL Surgery
Comparing Visual Outcomes in Matched Patients Receiving a Low Cylinder Power Toric IOL or a Non-toric IOL
The purpose of the study is to determine if visual function is improved with implantation of a low-cylinder toric intraocular lens, relative to a non-toric intraocular lens.
- Trial name
- NCT06717607
- Testing
- low cylinder toric IOL, non-toric IOL implantation
- Where
- Norway
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Ifocus Oyeklinikk
Aphakia, Cataract
One-Piece Hydrophobic Acrylic Intraocular Lens in Subjects Undergoing Cataract Extraction
The objective of this study is to evaluate the safety and effectiveness of the enVista® One-Piece Hydrophobic Acrylic intraocular lens (IOL), following primary implantation for the visual correction of aphakia in adults 18 years…
- Trial name
- NCT01230060
- Testing
- enVista
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- Bausch & Lomb Incorporated
Strabismus
Anesthetic Depth and the Incidence of Emergence Agitation in Children Undergoing Strabismus Surgery
This study evaluates the association between the depth of general anesthesia and the occurrence of emergence agitation (EA). The investigators hypothesized that optimal level of anesthetic depth could decrease the incidence of EA…
- Trial name
- NCT02521259
- Testing
- BIS
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Seoul National University Bundang Hospital
Refractive Errors
Early Feasibility Study to Evaluate the AccuraSee in Correcting Residual Refractive Errors After Cataract Surgery
To determine if the intraocular pseudophakic contact lens (IOPCL), referred to as the AccuraSee, corrects residual refractive errors after cataract surgery using a plus powered lens in subjects with ocular pathology previously…
- Trial name
- NCT05113979
- Testing
- AccuraSee IOPCL with +3.0D add
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- OnPoint Vision Inc