Clinical trials: Ophthalmic Surgery, active
Thyroid Surgery, Parathyroid Dysfunction
PTeye vs Surgeons Eyes in Intraoperative Identification and Functional Preservation of Parathyroid Glands During Thyroid Surgery: A Parallel Randomized Controlled Clinical Trial.
The goal of this randomized clinical trial is to learn if there are any added benefits of using near-infrared autofluorescence (NIRAF) probe-based imaging system (the PTeye) for intraoperative identification of parathyroid glands…
- Conditions
- Thyroid Surgery, Parathyroid Dysfunction, Hypoparathyroidism Post-surgical
- Trial name
- PTSURGEYE (NCT06765941)
- Testing
- Probe-based near-infrared parathyroid autofluorescence detection system, Surgeons naked eyes for parathyroid glands identification
- Where
- Poland
- Volunteers
- 154 people
- Sponsor
- Marcin Barczynski
Dry Eye
Efficacy of Kera Sol Tears on Signs and Symptoms of Surgical Temporary Ocular Discomfort Syndrome (STODS) in Subjects Following LASIK
Collecting data using Kera Sol tear usage during the initial two-week post-operative period after Laser-Assisted In Situ Keratomileusis (LASIK) has on the signs and symptoms of surgical temporary ocular discomfort syndrome (STODS)
- Trial name
- NCT07155070
- Testing
- Kera Sol Eye Drops
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vance Thompson Vision
Cataract (Post-operative Cataract Surgery Follow-up)
Vision Center Determinants of Cataract Follow-Up in Rural India
Cataract remains the leading cause of avoidable blindness in India despite substantial expansion of surgical services over the past two decades.
- Trial name
- NCT07513402
- Testing
- Follow-Up Strengthening Intervention Framework
- Volunteers
- 150 people
- Sponsor
- Seva Canada Society
Myopic Traction Maculopathy
Predictors of Vitrectomy Outcomes in Myopic Foveoschisis
This prospective pilot study evaluates factors that predict outcomes after vitrectomy for myopic foveoschisis (MFS), a sight-threatening complication of high myopia that can lead to progressive visual loss, foveal detachment…
- Trial name
- NCT07774637
- Testing
- pars plana vitrectomy
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Singapore National Eye Centre
Dry Eye Disease (DED)
Evaluating Crosslinked Hyaluronate Canalicular Gel for the Treatment of DED in Patients Undergoing Cataract Surgery
To review how patients report using a hyaluronate crosslinked canalicular gel placed before cataract surgery
- Trial name
- LaReCa (NCT07155057)
- Testing
- Cross-Linked Hyaluronate Gel Prefilled Syringe 30 MG/3ML
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vance Thompson Vision
Orthopedic Surgery, Nursing Care
Effect of Earplugs and Eye Masks Used After Orthopedic Surgery on Comfort and Quality of Recovery
This research will be conducted as a randomized controlled trial to determine the effects of earplugs and eye masks used after orthopedic surgery on comfort and quality of recovery.
- Conditions
- Orthopedic Surgery, Nursing Care, Quality of Recovery 40, Comfort
- Trial name
- NCT06986408
- Testing
- Earplugs and Eye Masks
- Volunteers
- 60 people
- Sponsor
- Ankara Yildirim Beyazıt University
Cataract, Cataract (Post-operative Cataract Surgery Follow-up)
Randomized Controlled Trial of the STEIN Protocol: A Neuroplastic Pain Education and Guided Breathing Intervention During Awake Cataract Surgery
This randomized controlled trial evaluates whether a standardized perioperative neuroplastic intervention: the STEIN Protocol (Strategies and Techniques for Enhancing Integration and Neuroplasticity), consisting of pain…
- Trial name
- SLin (NCT07715591)
- Testing
- Music and Guided Imagery, Control, Music Only
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of California, Los Angeles
Cataract Surgery
Reducing Patient Waiting Time for Cataract Surgery
The purpose of this study is to examine how coordination between hospital departments affects patient flow between the free ward (B1), paid ward (C1) and the operating theatre (OT) for cataract surgeries at a tertiary eye care…
- Trial name
- NCT07484659
- Testing
- Standard Operating Procedures (SOPs)
- Where
- India
- Volunteers
- 360 people
- Sponsor
- Seva Canada Society
Cataract Surgery, Eye Dryness
Low-level Light Therapy Versus Intense Pulsed Light to Prevent Iatrogenic Dry Eye Disease After Cataract Surgery
Dry eye disease (DED) is a frequent ocular surface disease (OSD) of multifactorial origin, characterised by disruption of tear film homeostasis and associated with ocular discomfort and/or visual disturbance.
- Trial name
- EDACS (NCT07055022)
- Testing
- LLLT, IPL
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Clinique Trenel
IOL, Cataract
Post-Market Clinical Follow-Up Study on the Rotational Stability of an Intraocular Lens After Cataract Surgery
The goal of this post-market, prospective study at multiple clinics is to evaluate the rotational stability of the RayOne Model RAO800S non-toric monofocal intraocular lens with orientation marks in adult patients undergoing…
- Trial name
- NCT07099079
- Volunteers
- 92 people
- Sponsor
- Rayner Intraocular Lenses Limited
Myopia, Astigmatism
SMILE Surgery in One Eye Compared to Ray Tracing-guided LASIK Surgery in the Fellow Eye
Participants will undergo LASIK surgery in one eye using ray tracing guided technology in one eye and LASIK surgery in the other eye using wavefront guided technology.
- Trial name
- NCT07721714
- Testing
- Ray tracing guided LASIK surgery
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Stanford University
Macular Hole, Macular Hole Surgery
Minimal Vitrectomy and ILM Flap with Sodium Hyaluronate Gel for MH
The purpose of this clinical trial is to compare the prognostic validity of two different surgical approaches: minimal posterior pole vitrectomy combined with a sodium hyaluronate gel-covered internal limiting membrane(ILM) flap…
- Conditions
- Macular Hole, Macular Hole Surgery, Idiopathic Macular Hole, Macular Hole of Left Eye (Disorder)
- Trial name
- ILM MH (NCT06685328)
- Testing
- minimal posterior pole vitrectomy combined with a sodium hyaluronate gel-covered internal limiting membrane(ILM) flap with balanced saline filling and postoperative supine position, Conventional vitrectomy combined with inner limiting membrane flap flip coverage with sterile air filling and postoperative prone position
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Jie Zhong
Normal Tension Glaucoma, Cataract
Endoscopic Cyclophotocoagulation in Normal Tension Glaucoma
The purpose of this study is to assess whether endoscopic cyclophotocoagulation added to cataract surgery lowers intraocular pressure more than cataract surgery alone in patients with normal tension glaucoma.
- Trial name
- ECPNTG (NCT04651530)
- Testing
- Phaco, Phaco+ECP
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Helsinki University Central Hospital
Aortic Diseases, Cardiac Surgical Procedures
Selective Antegrade Cerebral Perfusion and Perioperative Optic Nerve Sheath Diameter in Ascending Aortic Surgery
In ascending aortic surgery the distal anastomosis may be constructed with the aortic cross-clamp maintained, or, where the extent of the aortic pathology and the geometry of the graft require it, after release of the cross-clamp…
- Conditions
- Aortic Diseases, Cardiac Surgical Procedures, Aortic Aneurysm, Thoracic, Delirium - Postoperative
- Trial name
- SACP-ONSD (NCT07800806)
- Testing
- Optic nerve sheath and optic nerve diameter ultrasonography, Transcranial Doppler ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people
- Sponsor
- Koşuyolu Kartal Heart Training and Research Hospital
Glaucoma
Efficacy and Safety of XEN63 Gel Implant
The study is prospective, observational, multicenter and has the aim of evaluating the efficacy and safety of the XEN63 implant in patients with primary or secondary glaucoma who require surgery in association or not with…
- Trial name
- XEN63 (NCT06844240)
- Where
- 19 sites in Italy
- Volunteers
- 96 people
- Sponsor
- Mario Stirpe
Pterygium
Comparing Two Surgical Methods to Prevent Pterygium Regrowth
This study compares two surgical techniques for preventing the regrowth of a pterygium, a non-cancerous growth on the eye. After surgically removing the pterygium, surgeons will cover the area with either a flap of nearby tissue…
- Trial name
- NCT07277426
- Testing
- Conjunctival Rotational Flap, Conjunctival Autograft
- Volunteers
- 342 people
- Sponsor
- College of Physicians and Surgeons Pakistan
Glaucoma
INTEGRAL Study: A Longitudinal Study of Surgeries and Lasers in Glaucoma
The aim of this study is to create a large-scale register of all glaucoma patients diagnosed, followed and treated in a large tertiary centre specialising in glaucoma, in order to analyse whether specific factors influence the…
- Trial name
- NCT06227299
- Where
- Switzerland
- Volunteers
- 5,000 people
- Sponsor
- Swiss Glaucoma Research Foundation
Macular Holes, Epiretinal Membrane
Intraoperative OCT Guidance of Intraocular Surgery II
The overall five-year goals of the project are to develop novel technology to provide actionable new information through provision of live volumetric imaging during surgery, improving surgical practice and outcomes.
- Conditions
- Macular Holes, Epiretinal Membrane, Diabetic Retinopathy, Retinal Detachment
- Trial name
- MIOCT (NCT03713268)
- Testing
- Microscope integrated optical coherence tomography
- Where
- United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Duke University
Primary Open Angle Glaucoma
Cataract Surgery in Conjunction With Ab-interno Canaloplasty Compared to Cataract Surgery Only in Patients With Mild to Moderate Primary Open-Angle Glaucoma
A prospective, multicenter, randomized, single-masked, post-market clinical trial comparing cataract surgery in conjunction with ab-interno canaloplasty utilizing the iTrack Advance canaloplasty device (Nova Eye, Inc.) to…
- Trial name
- CATALYST (NCT05564091)
- Testing
- Cataract surgery combined with ab-interno canaloplasty utililzing the iTrack Advance canaloplasty device, Cataract surgery
- Where
- 4 sites in United States, Germany
- Volunteers
- 78 people
- Sponsor
- Nova Eye, Inc.
Deprivation Amblyopia, Congenital Cataract
Augmented Reality Training for Amblyopia After Congenital Cataract Surgery
This study will evaluate whether augmented reality training is effective and safe for treating unilateral amblyopia after congenital cataract surgery in children.
- Trial name
- NCT07693790
- Testing
- Augmented Reality Amblyopia Training, Conventional Patching
- Volunteers
- 88 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University