Clinical trials: Ophthalmological Disorder
Myopia
The Contact Lens and Myopia Progression (CLAMP) Study
To examine the effects of rigid gas permeable contact lenses on the progression of myopia (nearsightedness) in children To determine what changes in the eyes cause certain eyes to progress in nearsightedness more slowly
- Trial name
- NCT00009529
- Where
- United States
- Sponsor
- National Eye Institute (NEI)
Retinitis Pigmentosa
Transcorneal Electrical Stimulation - Multicenter Safety Study
The purpose of this study is to expand the safety assessment of repeated applications of an electrical current from a DTL-like electrode in patients with RP.
- Trial name
- NCT01835002
- Testing
- Transcorneal electrostimulation
- Where
- 7 sites in Denmark, Germany and 1 more
- Volunteers
- 105 people
- Sponsor
- Okuvision GmbH
Cataract
Study of Intracameral Adrenaline for Pupil Dilation Without Topical Mydriatics in Refractive Cataract Surgery
The purpose of this study is to study the safety and efficacy of intracameral adrenaline for pupil dilation without topical mydriatics in refractive cataract surgery.
- Trial name
- NCT01264653
- Testing
- adrenalin
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wenzhou Medical University
Vision Disorders, Strabismus
Vision in Children Born to Opioid-dependent Methadone-maintained Mothers
The investigators will re-investigate 150 children studied extensively in the past. 100 of these children were born to mothers prescribed methadone during their pregnancy because of opiate dependency, and 50 were comparison…
- Conditions
- Vision Disorders, Strabismus, Nystagmus, Binocular Vision Disorder
- Trial name
- VINCH (NCT03603301)
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- NHS Greater Glasgow and Clyde
Peripheral Vascular Access in Pediatric Patients, Peptic Ulcer
The Effect of Vascular Imaging Devices on Success Rates of Peripheral Vascular Access in Pediatric Patients
The study was designed as a prospective, observational study. Pediatric patients under 18 years of age scheduled for peripheral vascular access placement during day-case surgery or non-operating room anesthesia (NORA) will be…
- Conditions
- Peripheral Vascular Access in Pediatric Patients, Peptic Ulcer, Cataract, Crohn's Disease
- Trial name
- NCT07315711
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Sibel Seçkin Pehlivan
Retinal Vein Occlusion
To Study the Effectiveness and Safety of Niacin and a Topical Steroid Eye Drop to Treat Retinal Vein Occlusions
The purpose of this study is to determine whether Niacin, a B vitamin, may act as a vasodilator to encourage earlier formation of collateral blood vessels that may serve to bypass the obstructed vein in the eye.
- Trial name
- NCT00493064
- Testing
- Nicotinic acid, Prednisolone acetate
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Palo Alto Medical Foundation
Dry Eye Syndromes
Late Phase 2 Study of OPC-12759 Ophthalmic Suspension
The purpose of this study is to evaluate the dose-response of OPC-12759 suspension in dry eye patients
- Trial name
- NCT00475319
- Testing
- 1% OPC-12759 ophthalmic suspension, 2% OPC-12759 ophthalmic suspension
- Where
- 6 sites in Japan
- Volunteers
- 308 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Vitrectomy, Macular Pucker
Assessing the Efficacy and Safety fo DEXTENZA, Sustained Release Dexamethasone 0.4 mg Insert(s) for the Treatment of Pain, Inflammation, and Cystoid Macular Edema Following 27 Gauge Vitrectomy With Internal Limiting Membrane Peel for the Treatment of Retinal Edema Associated With Macular Pucker.
Assessing the efficacy and safety of DEXTENZA, sustained release dexamethasone 0.4 mg inserts following 27 gauge vitrectomy with internal limiting membrane peel
- Conditions
- Vitrectomy, Macular Pucker, Retinal Edema
- Trial name
- NCT04501367
- Testing
- Dexamethasone Intracanalicular Insert, 0.4 mg, Prednisone acetate 1%
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Kovach Eye Institute
Diabetic Retinopathy, Age Related Macular Degeneration
Retinal Care Data Repository
The Retinal Care Data Repository's primary objective is to make data available for Retinal Care to develop algorithms that improve the care of people with retinal diseases.
- Trial name
- NCT04794907
- Testing
- Observation
- Volunteers
- 1,000 people
- Sponsor
- Retinal Care Inc.
Vision Disorders
Modification in Cortical Activation in Pseudophakic Patients With Visual Difficulties After a Multifocal Implantation
This study will highlight differences in cortical activation between asymptomatic and symptomatic patients.
- Trial name
- PlainteIMF (NCT02529098)
- Testing
- fMRI
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Exudative Retinal Detachment, Uveal Melanoma
TTT Versus TTT and Triamcinolone to Decrease Exudation in Choroidal Melanoma After Proton Beam Therapy
Proton beam therapy is a safe irradiation modality for choroidal melanoma. But often after irradiation the exudation increases resulting in an exudative retinal detachment requiring vitreoretinal surgery.
- Trial name
- NCT02379000
- Testing
- Triamcinolone Acetonide, Transpupillary thermotherapy
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Charite University, Berlin, Germany
Corneal Neovascularization
Corneal Crosslinking for Treatment of Corneal Neovascularization
The study objective is to assess safety and efficacy of photo-activation of riboflavin for treatment of corneal neovascularization with or without concomitant inflammation and/or infection.
- Trial name
- NCT04787471
- Testing
- 30 minute photoactivation of riboflavin 0.1%, 10 minute photoactivation of riboflavin 0.1%
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- Price Vision Group
Renal Insufficiency, Chronic, Glaucoma
Intraocular Pressure and Hemodialysis Midwestern Brazil
Objective: To evaluate the variation in intraocular pressure in patients with chronic kidney disease, according to the time interval between hemodialysis sessions and to the influence of weight and blood pressure on intraocular…
- Trial name
- EHPIOBRAZIL (NCT02405884)
- Testing
- Kowa HA-2 Perkins applanation tonometer.
- Volunteers
- 39 people
- Sponsor
- VER Excelência em Oftalmologia
Cataract
NPI-002 Intravitreal Implant for the Delay of Cataract Progression
This study will examine the safety and efficacy NPI-002 intravitreal implants post vitrectomy.
- Trial name
- NCT05026632
- Testing
- NPI-002 Intravitreal Implant
- Where
- Australia
- Volunteers
- 24 people
- Sponsor
- Nacuity Pharmaceuticals, Inc.
Dry Eye Syndromes, Dry Eye
Prospective Study To Assess The Safety And Effectiveness Of Tixel Treatment On Dry Eye Symptoms In Asian Patients
Pilot study where effect of standard Tixel treatment as used for periorbital wrinkles would be assessed on Dry Eye Disease symptoms and signs in Asian Patients.
- Trial name
- DED (NCT04260893)
- Testing
- Tixel
- Where
- Cambodia
- Volunteers
- 44 people
- Sponsor
- Novoxel Ltd.
Myopia
Study of ACUVUE® ADVANCE® PLUS Contact Lenses.
The purpose of this study is to compare ACUVUE® ADVANCE® Plus contact lenses made prior to process qualification (prePQ) against the ACUVUE® ADVANCE® Plus lenses made after the process qualification (postPQ).
- Trial name
- NCT01244893
- Testing
- Acuvue Advance Plus prePQ, Acuvue Advance Plus postPQ
- Where
- 3 sites in United States
- Volunteers
- 44 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Ocular Itching, Ocular Allergy
Efficacy and Safety of PRO-118 Ophthalmic Solution in Allergic Conjunctivitis
The purpose of this study is to evaluate the efficacy and safety of four doses of PRO-118 ophthalmic solution ophthalmic solution compared with placebo, for the treatment of seasonal (SAC) and perennial (PAC) allergic…
- Conditions
- Ocular Itching, Ocular Allergy, Seasonal Allergic Conjunctivitis, Perennial Allergic Conjunctivitis
- Trial name
- PRO-118 (NCT01541904)
- Testing
- PRO-118 Ophthalmic Solution 0.015%, PRO-118 Ophthalmic Solution 0.015 %, PRO-118 Ophthalmic Solution 0.020 %
- Where
- 2 sites in Mexico
- Sponsor
- Laboratorios Sophia S.A de C.V.
Allergic Rhinitis, Asthma
The Significance of Ambrosia in Allergic Rhinitis and Asthma in Israel
Ambrosia is known for its allergenicity in the USA causing hay fever and asthma. Israel has always been considered "clean" of Ambrosia but over the past years growth of Ambrosia plants has been detected in several locations in…
- Conditions
- Allergic Rhinitis, Asthma, Allergic Conjunctivitis, Atopic Dermatitis
- Trial name
- NCT01686048
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Cataract
High-Definition 3D Visualization System for Ophthalmic Surgery
To validate a high-definition (HD) three-dimensional (3D) visualization system in cataract surgery
- Trial name
- NCT02194543
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Pediatric Disorder, Vitamin D Deficiency
Retinal Changes in Vitamin D Deficiency
Retinal tissue parameters of pediatric patients with vitamin D deficiency will be evaluated in this prospective case-control study. The patients will be divided into 2 groups according to the vitamin D level.
- Conditions
- Pediatric Disorder, Vitamin D Deficiency, Retinal Disease, Choroidal Disease
- Trial name
- VDD (NCT04891211)
- Testing
- Vitamin D deficiency
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Adiyaman University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.