Clinical trials: Opioid Consumption, Postoperative
Arthropathy of Hip, Hip Arthropathy
Pericapsular Nerve Group (PENG) Block Combined With Lateral Femoral Cutaneous Nerve (LFCN) Block or Wound Infiltration for Postoperative Analgesia in Anterior Approach Total Hip Arthroplasty: A Randomized Controlled Trial
This prospective, randomized controlled trial aims to compare two multimodal regional anesthesia strategies for postoperative analgesia in elective total hip arthroplasty (THA) performed via anterior approach.
- Conditions
- Arthropathy of Hip, Hip Arthropathy, Locoregional Anesthesia, Complication of Anesthesia
- Trial name
- Peng_lfcn/WI (NCT07284615)
- Testing
- PENG plus LFCN block, PENG plus WI
- Where
- Italy
- Volunteers
- 102 people
- Sponsor
- Ospedale Edoardo Bassini
Hip Osteoarthritis, Total Hip Arthroplasty (THA)
QIPB vs SI-FICB for Postoperative Analgesia After Total Hip Arthroplasty
Total hip arthroplasty (THA) causes moderate-to-severe postoperative pain. The PROSPECT guideline recommends the supra-inguinal fascia iliaca compartment block (SI-FICB) for THA, whereas evidence for newer…
- Conditions
- Hip Osteoarthritis, Total Hip Arthroplasty (THA), Postoperative Pain, Acute Pain
- Trial name
- NCT07683663
- Testing
- Supra-Inguinal Fascia Iliaca Compartment Block, Quadro-Iliac Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Dokuz Eylul University
Compartment Syndrome of Leg
Effects of Perioperative Patient Education Regarding Compartment Syndrome on Post-operative Opioid Consumption
This study is a prospective, randomized trial. Our study aims to study the effects of perioperative patient education about compartment syndrome on patients' perception of their own pain, amount of opioid medication utilization…
- Trial name
- NCT03359031
- Testing
- Patient education
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Rothman Institute Orthopaedics
Postoperative Pain
Comparison of SE-TAP, M-TAPA, and Rectus Sheath Block in Abdominal Surgeries
The aim of this randomised controlled study is to compare the effects of three different fascial plane block [subcostal exterior semilunaris transverses abdominis plane (SE-TAP) block, modified thoracoabdominal nerves block…
- Trial name
- NCT05259345
- Testing
- Bilateral SE-TAP, Bilateral M-TAPA, Bilateral RSB
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Inonu University
MeSH C23.300.707.374.875, MeSH E01.370.388.250.520
Comparing Two Nerve Block Methods for Pain Relief in Laparoscopic Hernia Surgery
After inguinal hernia repair, patients having chronic pain approximately 20 percent. If patients don't have postoperatively acute pain, they will tend to have less chronic pain.
- Conditions
- MeSH C23.300.707.374.875, MeSH E01.370.388.250.520, MeSH E03.155.086.711, MeSH C23.550.767.700
- Trial name
- NCT07676123
- Testing
- Anterior Quadratus Lumborum Block, Ilioinguinal-Iliohypogastric Block
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ankara University
Postoperative Pain
Effects of TAP and QLB-1 Blocks on Opioid Consumption
Laparoscopic cholecystectomy is associated with less pain than open surgery and a shorter recovery time. While the type of pain experienced after laparoscopy differs from that experienced after laparotomy, it is predominantly…
- Trial name
- NCT06663345
- Testing
- Transversus Abdominis Plan Block (TAPB), Lateral Quadratum Lumborum (QLB-1) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Pain, Postoperative
Erector Spinae Plane Block Analgesia for Lumbar Spine Fusion Surgery
The purpose of this study was to investigate the effect of a bilateral ultrasound guided erector spinae plane block on the pain scores and opoid utiliziation in fusion surgery of the lumbar spine.
- Trial name
- NCT04749095
- Testing
- Erector spinae plane block
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Benha University
TURP(Transurethral Resection of Prostate)
Sacral Erector Spinae Plane Block in Transurethral Prostate Resection Surgery
The aim of this study is to investigate the effects of bilateral sacral erector spinae plane block on hemodynamic values, postoperative pain, analgesic use and patient satisfaction during operative period in Transurethral…
- Trial name
- NCT06962085
- Testing
- sacral erector spinae plane block group, Opioid Analgesics
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Adiyaman University
Postoperative Pain
Transversalis Fascia Plane Block Versus Low-Dose Intrathecal Morphine for Open Inguinal Hernia Repair
Open inguinal hernia repair is commonly associated with early postoperative pain, which may delay mobilization, reduce patient satisfaction, and increase opioid consumption.
- Trial name
- NCT07695935
- Testing
- Intrathecal morphine, Ultrasound-guided transversalis fascia plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Hitit University
Pain, Acute, Opioid Use
Femoral Triangle Block With Popliteal Plexus Block Versus Femoral Triangle Block Versus Adductor Canal Block for TKA
In this study we wish to investigate the analgesic effect 3 different nerve block regimes in patients following primary total knee arthroplasty (TKA).
- Conditions
- Pain, Acute, Opioid Use, Analgesia
- Trial name
- NCT04854395
- Testing
- Marcain 5 mg/ml
- Where
- Denmark
- Volunteers
- 165 people
- Sponsor
- Regionshospitalet Silkeborg
Pain After Total Knee Arthroplasty, Pain Management
Combined Distal Femoral Nerve Block for Pain Control After Knee Replacement
The goal of this clinical trial is to see whether a combined distal femoral nerve block improves pain relief after total knee replacement in adults having planned surgery.
- Trial name
- FEM-COMB (NCT07629388)
- Testing
- Combined distal femoral nerve block, Saphenous nerve block alone, Standard perioperative care in both groups
- Where
- France
- Volunteers
- 240 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Pain, Postoperative, Opioid Use
Efect of Erector Spina Plane Block on Mastectomy
After breast cancer surgery, more than 60% of patients experience persistent pain.Although opioids are the main method of use in postoperative pain management, there are side effects such as constipation, sedation, respiratory…
- Trial name
- NCT04824300
- Testing
- erector spinae block
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Marmara University
Pain, Postoperative, Analgesic Effect
Analgesic Efficacy of Different Liposomal Bupivacaine Doses in the Adductor Canal Block for Total Knee Arthroplasty
Total knee arthroplasty is a commonly performed orthopaedic surgery for the treatment of end-stage osteoarthritis when conservative management becomes ineffective.
- Conditions
- Pain, Postoperative, Analgesic Effect, Total Knee Arthroplasty, Liposomal Bupivacaine
- Trial name
- NCT06740214
- Testing
- 0.5% standard bupivacaine only, 1.33% liposomal bupivacaine with 0.5% standard bupivacaine, 1.33% liposomal bupivacaine only
- Where
- Hong Kong
- Volunteers
- 177 people
- Sponsor
- The University of Hong Kong
Postoperative Pain, Cholelithiasis
Effect of Labetalol, Magnesium Sulfate, or Lidocaine on Opioid Consumption During Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy (gallbladder removal) is one of the most common abdominal operations performed worldwide. Despite its minimally invasive approach, up to half of patients experience notable postoperative pain, which…
- Trial name
- NCT07865455
- Testing
- Labetalol, Magnesium Sulfate, Lidocaine
- Volunteers
- 90 people
- Sponsor
- Assiut University
Pain, Postoperative
Efficacy And Safety Of Parecoxib IV/IM 40 Mg Vs Placebo Following Sub Muscular Breast Augmentation
The present study aims to compare the pre-emptive analgesic efficacy of parecoxib 40 mg IV/IM versus placebo on reducing postoperative acute pain following submuscular breast augmentation.
- Trial name
- NCT00435747
- Testing
- PARECOXIB SODIUM
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pfizer
Methadone, Pain, Post Operative
Perioperative Methadone in Hip Fracture Patients
Postoperative analgesic treatment needs to be improved. Numerous studies suggest that a single dose of Methadone given during surgery significantly ameliorates postoperative pain and reduces postoperative opioid consumption.
- Conditions
- Methadone, Pain, Post Operative, Pain, Postoperative, Analgesics, Opioid
- Trial name
- NCT05581901
- Testing
- Methadone (Dose1), Methadone (Dose 2), Methadone (Dose 3)
- Where
- Denmark
- Volunteers
- 31 people
- Sponsor
- University of Southern Denmark
Opioid Abuse (Disorder), Opioid Analgesia
Reducing Opioid Use After Upper Extremity Surgery: Testing Lower Prescriptions and Pill Quantity
The goal of this clinical trial is to evaluate strategies for optimizing postoperative multimodal pain regimens and reducing opioid dependency in patients undergoing upper extremity surgery.
- Conditions
- Opioid Abuse (Disorder), Opioid Analgesia, Opioid Analgesic Adverse Reaction, Opioid Consumption
- Trial name
- NCT07750639
- Testing
- Naproxen, Acetaminophen, oxycodone
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- AdventHealth
Laparoscopic Abdominal Surgeries
Effect of Low-dose Pregabalin Retard (82.5 mg) Versus Standard-dose Pregabalin Retard (165 mg) on Postoperative Pain and Opioid Consumption After Elective Laparoscopic Abdominal Surgery
The goal of this clinical trial is to detect whether pregabalin retard (82.5 mg or 165 mg) improves analgesia after elective laparoscopic abdominal surgery in adults. It will also evaluate the safety of both doses.
- Trial name
- NCT07456761
- Testing
- Pregabalin retard 82.5 mg, Pregabalin retard 165 mg
- Volunteers
- 80 people
- Sponsor
- South Egypt Cancer Institute
Postoperative Analgesia, Pain, Postoperative
Superficial Serratus Plane Block for Modified Radical Mastectomy and Axillary Lymph Node Disection
Breast cancer is the most common type of cancer in women. Mastectomy and axillary lymph node disection are commonly performed as part of the cancer management. This surgery can cause significant postoperative pain.
- Conditions
- Postoperative Analgesia, Pain, Postoperative, Opioid Consumption
- Trial name
- NCT03341234
- Testing
- Bupivacaine, Saline, Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Ataturk University
Postoperative Pain, Total Hip Arthroplasty
Comparing Pericapsular Nerve Group Block with Lumbar Erector Spinae Plain Block in Total Hip Arthroplasty Surgery
Total hip arthroplasty is a common surgical procedure aiming to improve mobility and quality of life in patients suffering from hip pain.
- Trial name
- NCT06059339
- Testing
- Procedure/Surgery: Regional Block Comparison Comparing postoperative pain and opioid consumption in groups
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Marmara University