Clinical trials: Opioid Intoxication
Opioid Use Disorder, Alcohol Intoxication
Pain Sensitivity, Alcohol-Induced Analgesia, and Heavy Drinking in Individuals With Opioid Use Disorder
The goal of this clinical trial is to examine whether individuals with co-occurring opioid use disorder and alcohol use (OUD+ALC) experience heightened pain sensitivity, pain-related negative affect, and greater alcohol…
- Conditions
- Opioid Use Disorder, Alcohol Intoxication, Pain
- Trial name
- NCT07894276
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Ohio State University
Intoxication; Opioid
Early Addiction Care Pathway After Acute Drug Intoxication in Emergency Departments
Acute intoxication with psychoactive substances represents a major public health issue and a frequent reason for emergency department (ED) visits.
- Trial name
- IPAIS (NCT07738835)
- Testing
- Structured early addiction care, Not structured early addiction care
- Where
- 4 sites in France
- Volunteers
- 266 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Opioid Dependence, Opioid Intoxication
Naloxone to TReatment Entry in the Emergency Setting
The study tests a structured referral process for opioid overdose survivors, from pre-hospital emergency care to long-term treatment of the individual's substance use-related disorder.
- Conditions
- Opioid Dependence, Opioid Intoxication, Substance Use Disorders
- Trial name
- N-TREE (NCT03368794)
- Testing
- Active treatment referral of opioid overdose survivors to long-term treatment, Control
- Where
- Sweden
- Sponsor
- Anders C Håkansson
Opioid Addiction, Opioid Abuse, Continuous Use
Healthy Adult Male Facial Skin Surface Lipid Pheromone p.o. to Treat Opioid Addiction
Healthy adult human male facial skin surface lipid liquid pheromone given by mouth to opioid addicts cures them without any withdrawal symptoms whatsoever 250mg on chewing gum vehicle by mouth.
- Conditions
- Opioid Addiction, Opioid Abuse, Continuous Use, Opioid Use, Opioid-Related Disorders
- Trial name
- NCT03394911
- Testing
- 250mg healthy adult male facial skin surface lipid liquid pheromone
- Volunteers
- 500 people
- Sponsor
- Bubba Nicholson
Ventilatory Depression, Opioid Intoxication
Respiratory Control and Narcotic Effects
The aim of this study is to provide data that will assess the role of ventilatory chemosensitivity (respiratory drive) in determining postoperative respiratory depression due to opioids.
- Conditions
- Ventilatory Depression, Opioid Intoxication, Opioid Toxicity
- Trial name
- NCT04047550
- Testing
- Ventilatory chemosensitivity
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Duke University
Opioid; Intoxication, Perception Disturbance (Acute), Acute Pain
Pupillary Unrest in Ambient Light, and Relationship to Opioid-Induced Respiratory Depression
Volunteers will receive a weight-based opioid (remifentanil) infusion for 10 minutes. In the first run, serial pupillary measurements (pupillary unrest, pupil diameter) will be taken at baseline, and at 2.5-minute intervals…
- Conditions
- Opioid; Intoxication, Perception Disturbance (Acute), Acute Pain, Overdose of Opiate, Respiratory Depression
- Trial name
- NCT04301895
- Testing
- Continuous conversational interaction, Remifentanil infusion
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Opioid Intoxication
The Evaluation of Safety and Tolerance of Commercially Available Naltrexone Administered Daily - Assessment for CBRN Operations
The objective of this study is to evaluate the tolerance and safety of naltrexone while performing military specific tasks, and to assess plasma concentrations following naltrexone, administered orally at 50 mg per day for 7…
- Trial name
- TEST CANADA (NCT03879460)
- Testing
- Naltrexone Hydrochloride
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Timothy Smith