Clinical trials: Opioid Use, completed
Opioid Use Disorder, Pregnancy Related
Open Trial of Technology-Enhanced Behavioral Intervention for Buprenorphine Retention in Pregnant and Postpartum People
This study involves testing how useful a technology-enhanced intervention is for pregnant people prescribed buprenorphine for the management of opioid use disorder.
- Trial name
- NCT06496230
- Testing
- Empowering Pregnant Women and People Receiving Medications for Opioid Use Disorder
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Medical University of South Carolina
Opioid Use, Exercise
Effect of Increased Pain Tolerance on Exercise Performance
Clinical prescription and use of opioids is a clear problem in large parts of the world and has the recent years received an increasing publicity in sports.
- Trial name
- NCT03934411
- Testing
- Tramadol
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Opioid Use Disorder
START NOW in the Treatment of Opioid Addicted Individuals
This investigation involves a partially randomized clinical trial examining the effectiveness of combining buprenorphine/naloxone MAT with START NOW, a skills-based psychosocial intervention modified specifically for the…
- Trial name
- NCT05552040
- Testing
- START NOW Group
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Carilion Clinic
Sexual Violence, Posttraumatic Stress Disorder
Testing STAR and TexSTAR: A Video and Text Messaging Intervention
This NIDA-funded HEAL Initiative: Opioid Use Disorder Care Pathways for Individuals with Histories of Exposure to Violence R61 seeks to develop and test a brief video intervention to deliver during Sexual Assault Nurse Examiner…
- Conditions
- Sexual Violence, Posttraumatic Stress Disorder, Opioid Use, Opioid Misuse
- Trial name
- NCT06456190
- Testing
- Skills Training in Active Recovery (STAR) Video, Text Skills Training in Active Recovery (TextSTAR) program
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Wisconsin, Madison
Marijuana Use
Effects of a Range of Naltrexone Doses in Combination With Smoked Marijuana
The purpose of this study is to determine if the subjective effects of marijuana will be decreased by low-doses (< 25 mg) of naltrexone and increased by high-doses (> 50 mg) of naltrexone.
- Trial name
- NCT00403117
- Testing
- Naltrexone 12 Mg+ Active Marijuana (3.27% THC), Naltrexone 25 Mg + Active Marijuana (3.27% THC), Naltrexone 50 Mg+ Active Marijuana (3.27% THC)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Pain Management
Regional Anesthesia to Reduce Opioid Use Following Functional Endoscopic Sinus Surgery
Opioids are prescribed for moderate to severe pain disorders; however, there are contraindications and side effects that are common to all opioids.
- Trial name
- NCT03757715
- Testing
- Bupivacaine, Dexamethasone
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Alabama at Birmingham
Chronic Pain, Opioid Use Disorder
Virtual Reality for Chronic Pain and Opioid Use Disorder Pilot
This is a pilot feasibility study of a virtual reality device for patients with co-morbid chronic pain and opioid use disorder.
- Trial name
- NCT05546749
- Testing
- RelieVRx
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Albert Einstein College of Medicine
Endocarditis, Bacterial, Opioid-use Disorder
Combining Opioid Addiction Treatment Services With CARe for Infectious Endocarditis
Hospitalizations for severe infections associated with opioid use disorder (OUD), such as infective endocarditis (IE), have doubled in the US over the past decade and are frequently prolonged and resource-intensive.
- Conditions
- Endocarditis, Bacterial, Opioid-use Disorder, Buprenorphine, Outpatient Parenteral Antibiotic Therapy
- Trial name
- CATS-CARE (NCT03048643)
- Testing
- Outpatient parenteral antibiotic therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Laura Fanucchi
Opioid Use, Pain, Postoperative
SMS Education for Post-operative Pain
The purpose the research is to assess whether or not postoperative education and awareness about pain and opioid use through SMS text messages will reduce overall opioid utilization after common outpatient surgeries.
- Trial name
- NCT04039191
- Testing
- SMS education, SMS survey
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Cedars-Sinai Medical Center
Opioid-use Disorder
Project STAMINA (Syringe Service Telemedicine Access for Medication-assisted Intervention Through NAvigation)
Project STAMINA is a clinical trial that seeks to establish effectiveness of a telemedicine approach for linking syringe exchange clients to medications for opioid use disorder.
- Trial name
- STAMINA (NCT04575324)
- Testing
- Telemedicine Linkage Intervention
- Where
- United States
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Chestnut Health Systems
Opioid Use, Postoperative Pain
Comparison of Postoperative Analgesia Methods in Elective Cesarean Section Surgeries
Since many intravenous anesthetic agents administered to the mother can cross the placental barrier and cause fetal side effects, multimodal analgesia strategies with peripheral nerve blocks are preffered with greater safety in…
- Trial name
- NCT06425718
- Testing
- Postoperative Pain Management Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Marmara University
Pain, Cancer
Study of the Safety of BEMA™ Fentanyl Use for Breakthrough Pain in Cancer Subjects on Chronic Opioid Therapy
The purpose of this study is to evaluate the safety of BEMA fentanyl at any dose in the management of breakthrough pain in cancer subjects on background opioid therapy.
- Trial name
- NCT00293020
- Testing
- BEMA Fentanyl
- Where
- United States
- Volunteers
- 244 people
- Sponsor
- BioDelivery Sciences International
Marijuana Usage, Opioid Use
Opioid and Cannabinoid Interactions
This study will examine the effects of doses of marijuana/placebo and doses of opioid/placebo, alone and in combination. The primary outcomes are related to pharmacodynamic measures (subjective ratings of drug liking and other…
- Trial name
- NCT03705559
- Testing
- Vaporized Marijuana, Opioid Agonist
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Shanna Babalonis, PhD
Addiction, Opioid Use
Phase Ib/2a Drug-drug Interaction Study of a Combination of 45mg Dextromethorphan With 105 mg Bupropion
The overall goal of this project is to collect initial human data on the effects of novel compounds on safety (interactions with an opioid drug, e.g., buprenorphine) and early efficacy signals (subjective effects on negative…
- Conditions
- Addiction, Opioid Use, Substance Use Disorders, Opioid Use Disorder
- Trial name
- NCT05976646
- Testing
- Auvelity
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Virginia Commonwealth University
Chronic Pain, Opioid Use
Improving Pain Disability With the Use of Oral Cannabinoids
The investigators are conducting a pilot (i.e. a small study) in order to find out the effectiveness and safety of medical cannabis in the management of chronic pain.
- Conditions
- Chronic Pain, Opioid Use, Cannabis
- Trial name
- NCT05351905
- Testing
- CBD oil ( MPL-001), CDB+THC oil (MPL-005)
- Where
- Canada
- Volunteers
- 51 people
- Sponsor
- University Health Network, Toronto
Chronic Pain, Postoperative Pain
Risk of Failed Epidural in Patients With and Without Chronic Pain and Opioid Use
Patients with chronic pain syndrome (CPS) may develop central sensitization wich may lead to increased pain intensity and lower pain threshold sometimes to the extend of hyperalgesia and allodynia.
- Conditions
- Chronic Pain, Postoperative Pain, Central Sensitisation
- Trial name
- NCT05662566
- Testing
- Epidural replacement
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Eske Kvanner Aasvang
Opioid Use
Music Therapy for Post-cardiac Surgery Pain Management
Music therapy as a supplement to post surgery pain management in cardiac surgery patients following median sternotomy.
- Trial name
- NCT05098561
- Testing
- Music Treatment
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Steward St. Elizabeth's Medical Center of Boston, Inc.
Opioid Use, Unspecified
Educational Video on Pain Management and Subsequent Opioid Use After Cesarean Delivery
This is a randomized controlled trial assessing the utility of an educational video on pain management after a cesarean section to reduce opioid use.
- Trial name
- NCT03959969
- Testing
- Educational video, Standard of care, Ibuprofen
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Opioid Use Disorder
PEERS Pilot: Peer Recovery Support Program to Support Engagement in Medication for Opioid Use Disorder
The goal of this pilot study is to evaluate the feasibility and acceptability of implementing a peer recovery support program to support patient engagement in medication treatment for opioid use disorder (MOUD).
- Trial name
- PEERS (NCT06696066)
- Testing
- PRS Program
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Geisinger Clinic
Opioid-use Disorder
Extended-Release Buprenorphine vs. Sublingual Buprenorphine for the Treatment of Opioid Use Disorder
The study is 12-week, randomized, open-label study comparing injectable extended-release buprenorphine (Sublocade) to standard therapy (sublingual buprenorphine), to see if Sublocade will be more helpful in treating opiate use…
- Trial name
- NCT04352166
- Testing
- extended-release buprenorphine (BXR), sublingual buprenorphine (BSL)
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Frances R Levin