Clinical trials: Opioid Use Disorder, open to volunteers
Substance Use Disorder, Opioid Use Disorder
Testing the CrOss Systems Technical Assistance for Retaining Staff (COSTARS) Model for Improving Staff Retention Among Child Welfare Workers and Peer Supporters, and Implementation of Evidence Based Interventions.
The goal of this study is to test whether the CrOss System Technical Assistance for Retaining Staff (COSTARS) supervision leadership institute can promote workforce stability and improved implementation outcomes within the Ohio…
- Conditions
- Substance Use Disorder, Opioid Use Disorder, Child Maltreatment, Implementation
- Trial name
- COSTARS (NCT07439783)
- Testing
- COSTARS, Implementation As Usual
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Alicia Bunger
Opioid Use Disorder, Opioid Use Disorder, Moderate
Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder
The primary objective of this research study is to evaluate the effect of tirzepatide, relative to placebo, as an adjunct to BUP on retention, substance use, and sleep outcomes in individuals with OUD.
- Conditions
- Opioid Use Disorder, Opioid Use Disorder, Moderate, Opioid Use Disorder, Severe
- Trial name
- TAB (NCT06651177)
- Testing
- Tirzepatide
- Where
- 9 sites in United States
- Volunteers
- 310 people
- Sponsor
- T. John Winhusen, PhD
Chronic Pain
Pain Management Teams Using Whole Health to Optimize Function and Safety in Veterans: The TEAMWORK Trial
The focus of this study is to determine whether adding Whole Health Coaching (WHC) improves pain care among adults with chronic pain and who are currently working with a pain management team (PMT) at the VA.
- Trial name
- TEAMWORK (NCT07149870)
- Testing
- Pain Management Team + Whole Health Coach (PMT-WHC), Pain Management Team-Usual Care (PMT-UC)
- Where
- 5 sites in United States
- Volunteers
- 432 people
- Sponsor
- VA Office of Research and Development
Cocaine Use Disorder
Efficacy and Safety of Sustained-release Dexamphetamine in Patients With Moderate to Severe Cocaine Use Disorder
In The Netherlands, each year, about 15 thousand people come into treatment because of problems with cocaine use. There is no approved medication for treatment of cocaine addiction and the psychosocial treatment patients receive…
- Trial name
- NCT05529927
- Testing
- Sustained-release Dexamphetamine
- Where
- Netherlands
- Volunteers
- 204 people
- Sponsor
- Parnassia Addiction Research Centre
Opioid Use Disorder
Supporting Treatment for Opioids and Recovery Capital (STORC) - R61 Phase
We are studying whether training an identified support person and providing patient navigation (i.e. a peer recovery specialist assisting you with finding the right support) after delivery can increase "recovery capital"-the…
- Trial name
- STORC R61 (NCT07787039)
- Testing
- STORC
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Friends Research Institute, Inc.
HIV Infections, Opioid Use Disorder
NOTRE: Optimizing Long-Acting Pre-Exposure Prophylaxis and Medications for Opioid Use Disorder Interventions in Carceral Settings
The investigators plan to conduct an R61/33 hybrid type 2 implementation-effectiveness trial that includes 1) a one-year exploratory R61 phase that will enable the development of the intervention protocol needed for the R33 trial…
- Conditions
- HIV Infections, Opioid Use Disorder, Incarceration; Lens
- Trial name
- NOTRE (NCT06854029)
- Testing
- Cabotegravir Injection, Cabotegravir Pill, Buprenorphine injection
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Duke University
Opioid Use Disorder, Social Determinants of Health (SDOH)
Using Clinical Decision Support to Provide Social Risk-Informed Care for Opioid Use Disorder in the Emergency Department
The overarching goal of this proposal is to integrate patient social risk information into an existing electronic health record (EHR)-based clinical decision support (CDS) tool (CDSv1) to facilitate emergency department…
- Trial name
- NCT06872190
- Testing
- ED-Based Clinical Decision Support for Opioid Use Disorder, Social Care-Enhanced Clinical Decision Support for Opioid Use Disorder
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of California, San Francisco