Clinical trials: Opioid-Free Anesthesia
Opioid-Free Anesthesia, Elective Laparoscopic Cholecystectomy
Effect of Opioid-Free Anesthesia (OFA) on Postoperative Pain and Perioperative Nausea and Vomiting in Elective Laparoscopic .
1. To evaluate the efficacy of a standardized multimodal Opioid Sparing (OS) protocol versus conventional opioid-based analgesia in reducing acute postoperative 2.
- Trial name
- OFA (NCT07306910)
- Testing
- opoid free anesthesia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Assiut University
Opioid Free Anesthesia
Intraoperative Retrolaminar Block as Opioid Free Anesthesia After Posterior Lumber Spine Discectomy
Opioid-free intraoperative protocols have been successfully used in specific surgical populations with equal or superior results to classic general anesthetic approaches.
- Trial name
- NCT05312866
- Testing
- Standard analgesia (paracetamol +fentanyl), Retrolaminar block with bupivacaine + magnesium sulfate + dexamethasone
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Caudal Block, Pediatric Urologic Surgeries
Comparison of Caudal Block Combined With General Anesthesia and Penile Block and Intravenous Fentanyl in Pediatric Surgeries
Urogenital surgery is one of the most frequently performed surgical procedures in the pediatric patient population. There is no consensus on which analgesic method is most effective for pain control in these patients.
- Conditions
- Caudal Block, Pediatric Urologic Surgeries, Fentanyl, Pediatric Delirium
- Trial name
- NCT06862271
- Testing
- Group 1 ( Caudal block group ), Group 2 (Penile block and IV Fentanyl group)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Miray Gözde Özdemir
Opioid-free Anesthesia
Opioid Free Anesthesia on the Quality of Early Recovery
To analyze and compare the effect of OFA scheme and traditional balanced anesthesia scheme on QoR15 after thyroidectomy, and further clarify the safety and rationality of OFA scheme in perioperative application of thyroid surgery.
- Trial name
- opioid-free (NCT05577962)
- Testing
- OFA group (group T)
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Opioid Free Anaesthesia
Comparison of Opioid Based and Opioid Free Anaesthesia in Transsphenoidal Surgery
This study has been planned to compare the effect of opioid free anaesthesia using dexmedetomidine and ketamine with opioid based anaesthesia using fentanyl in maintaining the intraoperative hemodynamic stability and recovery…
- Trial name
- NCT03120234
- Testing
- Dexmedetomidine, Ketamine, Fentanyl
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Postoperative Pain
Opioid-Free vs Opioid-Based Anesthesia for Nasal Surgeries
The goal of this clinical trial is to evaluate and compare the efficacy, onset, duration of action, analgesic effect, and side effects of opioid-free anesthesia using dexmedetomidine and lignocaine versus conventional…
- Trial name
- Dex/Lido/Fent (NCT07350668)
- Testing
- dexmedetomidine and lignocaine infusion, Fentanyl infusion
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Benha University
Deviated Septum, Opioid Free Anesthesia
Opioid Free Versus Opioid Based General Anesthesia in Septoplasty Under Nociception Level Guidance
Prospactive observational Clinical study
- Trial name
- NCT07786727
- Testing
- OFA
- Where
- Greece
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Narcotics, Recovery Quality
Quality of Recovery Following Opioids Free Anaesthesia in Laparoscopic Sleeve Gastrectomy
Laparoscopic sleeve gastrectomy is widely employed nowadays. Multimodal analgesia approach is implemented within the enhanced recovery protocol in our facility to improve participants' recovery.
- Conditions
- Narcotics, Recovery Quality, Analgesia, Bariatric Surgery
- Trial name
- NCT04285255
- Testing
- Fentanyl, Ketamine, Dexmedetomidine Injection [Precedex]
- Where
- Saudi Arabia
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Al Mashfa Medical Center
Quality of Recovery, Pain, Postoperative
Quality of Recovery After Laparoscopic Cholecystectomy Comparing Opioid Free Analgesia Versus Opioid Free Anesthesia
The aim of this study is to compare the quality of recovery from general anesthesia and surgery using the quality of recovery 15 item scale (QoR-15) for participant's receiving opioid-Sparing anesthesia with those receiving…
- Conditions
- Quality of Recovery, Pain, Postoperative, Elective Laparoscopic Cholecystectomy
- Trial name
- NCT06343753
- Testing
- Opioid free analgesia, Opioid based Anesthesia
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University