Clinical trials: Opioid-free Anesthesia
Obesity, Bariatric Surgery
Opioid-Free Versus Opioid-Based Anesthesia in Bariatric
This study is designed as a prospective, randomized, controlled clinical trial. It will be conducted in the operating rooms of the University of Health Sciences, Diyarbakır Gazi Yaşargil Training and Research Hospital.
- Trial name
- NCT07105839
- Testing
- Intraoperative rescue analgesia, Intraoperative rescue analgesia:
- Volunteers
- 50 people
- Sponsor
- Siirt Training and Research Hospital
Analgesia After Laparoscopic Cholecystectomy
Opioid-Free Analgesia for Laparoscopic Cholecystectomy
laparoscopic cholecystectomy (LC) is often accompanied by moderate-to-severe postoperative pain. opioid-free anesthesia (OFA) consists of a variety of non-opioid narcotic drugs and techniques.
- Trial name
- NCT07750769
- Testing
- EOI with OFA, OFA
- Volunteers
- 70 people
- Sponsor
- Assiut University
Analgesics, Opioid, Anesthesia, General
Asleep Fiberoptic vs Direct Laryngoscopy Effect on Hemodynamic Stability Using Opioid Free Anesthesia Induction
The goal of this clinical trial is to compare heart rate between the fiberoptic and direct oral intubation using opioid free anesthesia induction.
- Conditions
- Analgesics, Opioid, Anesthesia, General, Heart Rate, Blood Pressure
- Trial name
- NCT06487988
- Testing
- direct conventional laryngoscopy, fiberoptic guided intubation
- Where
- Lebanon
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Postoperative Pain
Effect of OFA in Laparoscopic Gastrectomy
The investigator will examine the effects of opioid free anesthesia in patients undergoing laparoscopic gastrectomy. The investigator expect that opioid free anesthesia will reduce postoperative pain and opioid consumption.
- Trial name
- NCT05076903
- Testing
- OFA, Control
- Where
- 2 sites in South Korea
- Volunteers
- 120 people
- Sponsor
- Gangnam Severance Hospital
Morbid Obesity, Postoperative Pain
Opioid-Free vs Opioid-Based Anesthesia in Bariatric Surgery
This prospective randomized controlled trial aims to compare the clinical effectiveness and safety of opioid-free anesthesia (OFA) versus traditional opioid-based anesthesia (OBA) in adult patients undergoing laparoscopic…
- Conditions
- Morbid Obesity, Postoperative Pain, Opioid Free Anesthesia, Bariatric Surgery
- Trial name
- NCT07337135
- Testing
- Opioid-Based Anesthesia (Remifentanil-Based Protocol), Opioid-Free Anesthesia (Dexmedetomidine-Ketamine-Lidocaine Protocol)
- Where
- Portugal
- Volunteers
- 60 people
- Sponsor
- Hospital dos Lusíadas
Colorectal Cancer
Analgesic Efficacy of Free-opioid Anesthesia for Colorectal Surgery
Objectives: To compare free-opioid anesthesia (the combination of epidural anesthesia, intravenous lidocaine, ketamine, propofol, and sevoflurane) and opioid anesthesia (fentanyl, propofol and sevoflurane) regarding…
- Trial name
- NCT06042816
- Testing
- Free-opioid anesthesia, opioid anesthesia
- Where
- Vietnam
- Volunteers
- 49 people
- Sponsor
- Vietnam Military Medical University
Pain, Postoperative, Acute Pain
EFFECT - EFFectiveness of ESPB (Erector Spinae Plane Block) in Laparoscopic Cοlectomies Trial
The aim of the trial is to study the efficacy of continuous bilateral Erector Spinae Plane Block (ESPB) in managing perioperative pain in patients who undergo elective laparoscopic colectomy.
- Conditions
- Pain, Postoperative, Acute Pain, Postoperative Complications, Pain
- Trial name
- EFFECT (NCT04879004)
- Testing
- Ropivacaine injection
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Democritus University of Thrace
Cervix Cancer, Endometrial Cancer
Opioid Free Anaesthesia in Oncologic Gynaecological Surgery: Is There Any Benefit?
Opioid Free Anesthesia (OFA) is a multimodal anesthesia and emerging technique that spares the use of opioids and involve other adjuvant anesthetics, which have demonstrated in vitro influence on immunologic and inflammatory…
- Conditions
- Cervix Cancer, Endometrial Cancer, Ovarian Cancer, Breast Cancer
- Trial name
- NCT05448586
- Testing
- Opioid
- Where
- Spain
- Volunteers
- 132 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Anesthesia, Opioid Use
Opioid-Free Anesthetic for Tonsillectomy
Prospective randomized controlled trial to determine if opioid-free anesthetic for tonsillectomy is non-inferior to standard opioid-containing anesthetic
- Conditions
- Anesthesia, Opioid Use, Tonsillitis, Sleep Disorder
- Trial name
- NCT04528173
- Testing
- Ketorolac, Dexmedetomidine, Morphine
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Surgery, Anesthesia
Opioid-Free Anesthesia in Modified Radical Mastectomy
The aim of this study is to evaluate the efficacy of opioid-free general anesthesia for breast surgeries in female patients.
- Conditions
- Surgery, Anesthesia, Opioid Use
- Trial name
- NCT05693402
- Testing
- opioid anesthesia
- Where
- Lebanon
- Volunteers
- 116 people
- Sponsor
- Etienne El Helou
Posoperativ Pain, Chronich Pain
Opioid-Free Anesthesia and Pain Study in Cardiac Surgery Patients
The goal of this clinical trial is to compare the effect of opioid-free anesthesia on the intensity of acute and chronic postoperative pain in patients undergoing cardiac surgery.
- Conditions
- Posoperativ Pain, Chronich Pain, Postoperativ Delirum, Opoid-free Managment
- Trial name
- OFPAINS-CS (NCT07618130)
- Testing
- Opioid Free Anaesthesia, Opioid Anesthesia
- Where
- Serbia
- Volunteers
- 400 people
- Sponsor
- Clinical Centre of Serbia
Thoracic, Surgery
Opioid-free Anesthesia in Thoracic Surgery
No study has been conducted to demonstrate the feasibility and safety of an Opioid-Free Anesthesia (OFA) protocol compared to Opioid-Based Anesthesia (OBA) in thoracic surgery, at risk for intense post-operative pain, to improve…
- Trial name
- VATOFA (NCT04246099)
- Testing
- Post-operative care
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Adverse Effect of Drugs and Medicaments in Therapeutic Use, Adverse Effects in the Therapeutic Use of Anaesthetics
The Effect of Opioid Free Anesthesia in Bariatric Surgeries
This is a prospective randomized controlled study that will be carried out on morbid obese patients admitted to Tanta University hospitals for laparoscopic bariatric surgeries.
- Trial name
- Opioidfree (NCT04048200)
- Testing
- Fentanyl, Dexmedetomidine Ketamine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Opioid Free Anaesthesia, Opioid Anaesthesia
LIdocaine veRsus Sufentanil Anaesthesia in Cardiac Surgery With Cardiopulmonary Bypass
Since the 90's the concept of morphine sparing and morphine free anaesthesia (OFA) has progressively developed in non-cardiac surgery.
- Trial name
- LISRACC (NCT05136794)
- Testing
- Data collection
- Where
- France
- Volunteers
- 1,772 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Opioid Use, Unspecified, Bariatric Surgery Candidate
Effect of Opioid Free Anesthetic on Post-Operative Opioid Consumption After Laparoscopic Bariatric Surgery
A comparison of post-operative opioid use in laparoscopic bariatric surgery patients receiving opioid or opioid-free anesthesia.
- Conditions
- Opioid Use, Unspecified, Bariatric Surgery Candidate, Anesthesia
- Trial name
- NCT04081545
- Testing
- Opioid Anesthetics, Non Opioid Analgesics
- Where
- United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Christine Oryhan