Clinical trials: Opioids; Harmful Use
Opioid-use Disorder, Harmful; Use, Alcohol
Patient Driven Recovery With Nalmefene and Coaching
In collaboration with the First Pavlov State Medical University in St. Petersburg, Russia, we are proposing a pilot, open label, non-randomized clinical trial to evaluate the safety, feasibility, acceptability, and preliminary…
- Trial name
- NCT03279562
- Testing
- Nalmefene
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Yale University
Opioid Use, Opioids; Harmful Use
Evaluation of a Patient-Centred, Multidisciplinary Opioid Tapering Program for Individuals With Chronic Non-Cancer Pain on Long Term Opioid Therapy
Chronic pain management is complex, with healthcare providers historically relying on prescribing opioid medications such as morphine.
- Conditions
- Opioid Use, Opioids; Harmful Use, Hyperalgesia, Pain, Chronic
- Trial name
- NCT04902547
- Testing
- Patient Education Workshop (PEWs), Multidisciplinary Tapering Program
- Where
- 4 sites in Canada
- Volunteers
- 26 people
- Sponsor
- University of Manitoba
Mental and Behavioral Disorders Due to Use of Cocaine: Harmful Use, Opiate Addiction
Recovery Housing and Drug Abuse Treatment Outcome
Reinforcement-Based Therapy (RBT) is an intensive outpatient substance abuse treatment that includes relapse prevention skills training, goal setting, help with finding employment and abstinence-contingent rent payment for…
- Trial name
- NCT03278496
- Testing
- Recovery Housing plus Counseling, Usual Care Referral, Recovery Housing Only
- Where
- United States
- Volunteers
- 243 people
- Sponsor
- Johns Hopkins University
Addiction, Opioid Dependence
Exploratory Dose Ranging Study Assessing APH-1501 for the Treatment of Opioid Addiction
The purpose of this study is determine the safety, efficacy and tolerability of a novel drug APH-1501 as a pharmacotherapy for Opioid Dependence. The investigators will evaluate the safety of escalating doses APH-1501.
- Conditions
- Addiction, Opioid Dependence, Opioid Withdrawal
- Trial name
- NCT03813095
- Testing
- APH-1501
- Volunteers
- 32 people
- Sponsor
- Aphios
Post-operative Pain, Acute, Cesarean Section
Management of Postoperative Pain After Cesarean Delivery Using Bridge Auricular Percutaneous Nerve Field Stimulator
Post-cesarean section (CS) pain is commonly treated with acetaminophen, ibuprofen, and opioid medications as needed following delivery.
- Conditions
- Post-operative Pain, Acute, Cesarean Section, Opioid Use Disorder, Opioids; Harmful Use
- Trial name
- NCT06434714
- Testing
- Auricular percutaneous nerve field stimulator
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Inova Health Care Services
Pain, Postoperative, Pain, Acute
Pectoral Nerve Blocks (PECs) for Cardiovascular Implantable Electronic Device Placement
The purpose of this study is to determine whether administration of a pectoral nerve blocks (Pecs I and II) with 0.25% bupivacaine are more effective as compared to placebo to provide analgesia for cardiac implantable electronic…
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Chest, Pain
- Trial name
- NCT05283980
- Testing
- 0.25% Bupivacaine
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Chronic Pain, Opioid-use Disorder
Pain and Opioids: Integrated Treatment In Veterans
This trial will recruit veterans with chronic pain (N = 160) who are prescribed buprenorphine for the treatment of opioid use disorder (OUD).
- Conditions
- Chronic Pain, Opioid-use Disorder, Opioids; Harmful Use
- Trial name
- POSITIVE (NCT04648228)
- Testing
- ACT+MBRP, Education control
- Where
- 4 sites in United States
- Volunteers
- 157 people
- Sponsor
- University of New Mexico
Opioids; Harmful Use
Piloting a Naloxone Intervention in Philadelphia
The escalating opioid overdose epidemic is one of the most serious public health problems confronting the U.S. Death due to drug overdose is a significant and rising cause of mortality and morbidity in Philadelphia.
- Trial name
- NCT03305497
- Testing
- Mobile Phone Application
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Drexel University
Narcotic Use, Postoperative Pain
A Prospective Assessment of Opioid Utilization Post-operatively in Sports Orthopaedic Surgeries
There was a study titled "A prospective evaluation of opioid utilization after upper extremity surgical procedures: Identifying consumption patterns and determining prescribing guidelines" by Dr.
- Conditions
- Narcotic Use, Postoperative Pain, Narcotic Abuse, Opioid Use
- Trial name
- Opioids (NCT03422211)
- Testing
- Questionnaire
- Where
- 3 sites in United States
- Volunteers
- 223 people
- Sponsor
- St. Louis University