Clinical trials: Optical Coherence Tomography (OCT)
- Condition Optical Coherence Tomography (OCT)
- Funder type Industry (pharma, biotech, devices)
- Accepts healthy volunteers yes
Retinal Dystrophies, Color Vision Defects
Natural History Study of Inherited Retinal Diseases
This prospective, observational investigation seeks to delineate the interplay between chromatic vision deficits and both functional visual outcomes and anatomical retinal biomarkers in individuals affected by Inherited Retinal…
- Conditions
- Retinal Dystrophies, Color Vision Defects, Vision Disorders, Macular Degeneration
- Trial name
- MojiLVCDT (NCT07085533)
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Augelux Therapeutics
Healthy
Optical Coherence Tomography (OCT) Normative Data Collection Study
This study is being initiated to create a normal database including measures of optic nerve head (ONH), peripapillary retinal nerve fiber layer (RNFL), and macula using the Heidelberg Spectralis OCT device.
- Trial name
- S-2013-3 (NCT02014688)
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Heidelberg Engineering GmbH
Retinal Disease, Glaucoma
Topcon 3D OCT-1000 Optical Coherence Tomography System
The purpose of this clinical protocol is to perform a comparison of Retinal and Retinal Nerve Fiber Layer (RNFL) thickness measurements between the Topcon 3D-1000 and the identified predicate device.
- Trial name
- NCT00792259
- Where
- 4 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Topcon Medical Systems, Inc.
Glaucoma, Retinal Disease
OCT Agreement and Crossed Precision Study
The purpose of this study is to asses the agreement of the RS-3000 Lite and RS-3000 Advance to the RS-3000, assess the crossed precision of each study device and to assess the transference of a reference database from the RS-3000…
- Conditions
- Glaucoma, Retinal Disease, Corneal Disease
- Trial name
- NCT02050880
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Nidek Co. LTD.
Coronary Artery Disease, Angina Pectoris
Lesional Evaluation of High Risk Patients With Neoatherosclerosis Treated With Rosuvastatin and Eicosapentaenoic Acid Using Optical Coherence Tomography(OCT)[LINK IT TWO]
This study aim is to evaluate the additional effect of eicosapentaenoic acid and dose up effect of rosuvastatin for neoatherosclerosis in coronary artery disease patients.
- Trial name
- NCT03657758
- Testing
- EPA and rosuvastatin, High dose rosuvastatin
- Where
- Japan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kobe University
Glaucoma, Retinal Disease
Nidek RS3000 Comparative Study
The primary objective of this clinical study is to compare the Nidek RS-3000 Optical Coherence Tomography (OCT) device to the Optovue RTVue OCT.
- Conditions
- Glaucoma, Retinal Disease, Corneal Disease
- Trial name
- NCT01384487
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Nidek Co. LTD.
Subjects Presenting With Normal or With Ocular Pathology
Clinical Validation of New OCT System
To demonstrate clinical substantial equivalence of DRI OCT-1 as comparable to the commercially available Cirrus
- Trial name
- NCT01809704
- Where
- 3 sites in United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Topcon Medical Systems, Inc.
Glaucoma
Optical Coherence Tomography (OCT) Reference Data Collection Study (S-2015-3)
This prospective, single-arm clinical multicenter study intends to measure normal structural parameters of the optic nerve head, the peripapillary retinal nerve fiber layer, and the macula using the Heidelberg Spectralis OCT…
- Trial name
- NCT02785042
- Testing
- Heidelberg Spectralis OCT
- Where
- 8 sites in United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Heidelberg Engineering GmbH
Normal Eyes, Eyes With Glaucoma
OCT Agreement and Precision Study
To demonstrate clinical substantial equivalence of 3D OCT-1 Maestro as comparable to the commercially available iVue and NW-300.
- Conditions
- Normal Eyes, Eyes With Glaucoma, Eyes With Retinal Disease
- Trial name
- NCT02045823
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Topcon Medical Systems, Inc.
Healthy
Optical Coherence Tomography (OCT) Normative Data Collection Study (S-2013-2)
This study is being initiated to create a normal database including measures of optic nerve head (ONH), peripapillary retinal nerve fiber layer (RNFL), and macula using the Heidelberg Spectralis OCT device.
- Trial name
- S-2013-2 (NCT02089711)
- Where
- Japan
- Volunteers
- 392 people, healthy volunteers welcome
- Sponsor
- Heidelberg Engineering GmbH
Healthy
OCT Reference Database
To collect data for a reference database.
- Trial name
- NCT01986478
- Where
- 5 sites in United States
- Volunteers
- 389 people, healthy volunteers welcome
- Sponsor
- Topcon Medical Systems, Inc.
Conductive Hearing Loss, Middle Ear
Ossiview Normative Mobility Data Collection Protocol
The goal of this observational study is to learn about the sound-induced vibration level of certain structures in the middle ear in the normal-hearing population.
- Trial name
- NCT06310278
- Testing
- Ossicular mobility measurement
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Audioptics Medical Incorporated
Healthy Eyes
Evaluation of the Signal to Noise Ratio at Various Retinal Layers
Compare the signal to noise ratio of each device at various retinal layers.
- Trial name
- NCT02982174
- Testing
- 3D OCT-1 Maestro, DRI OCT Triton
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Topcon Medical Systems, Inc.
Skin Care
Dynamic Optical Coherence Tomography(D-OCT) Aging Study: A Preliminary Evaluation of Structural Differences Between Young and Aged Skin, Cellulite and Atrophic Acne Scars in Female Caucasian Subjects With Fitzpatrick Skin Types I-III Utilizing Non-invasive in Vivo D-OCT.
This single-center clinical study is being conducted over the course of 2 weeks to conduct an exploratory pilot study as a preliminary evaluation of D-OCT's ability to measure skin changes from aging.
- Trial name
- NCT03767400
- Testing
- Skin Imaging, Facial Cleanser
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Allergan
No Eye Disease
Optical Coherence Tomography (OCT) Data Collection Study
Collect OCT data to evaluate the range and age trend of eye measurements.
- Trial name
- NCT01459731
- Where
- 5 sites in United States, United Kingdom
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Optovue
Glaucoma
Optical Coherence Tomography (OCT) Reference Data Collection Study (S-2015-1)
This prospective, single-arm clinical multicenter study intends to measure normal structural parameters of the optic nerve head, the peripapillary retinal nerve fiber layer, and the macula using the Heidelberg Spectralis OCT…
- Trial name
- NCT02785029
- Testing
- OCT
- Where
- 8 sites in United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- Heidelberg Engineering GmbH
Normal Subject, Glaucoma
Assessment of an Automated Optical Coherence Tomography and Camera : Effectiveness of Vision-700
The objective of study is to assess the repeatability and agreement of the retina and cornea measurement by Vision-700 in comparison with those by 3D OCT-1.
- Conditions
- Normal Subject, Glaucoma, Retinal Disease, Cornea
- Trial name
- NCT06496763
- Testing
- Vision-700
- Where
- Taiwan
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Crystalvue Medical Coporation
Healthy
Assessment of an Automated Optical Coherence Tomography and Camera : Reference Database
The objective of this study is to establish the Reference database of Vision-700.
- Trial name
- NCT06511440
- Testing
- Vision-700
- Where
- Taiwan
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Crystalvue Medical Coporation
Healthy
An Age-Stratified Data Collection Study to Establish a Normative Database Using the 3D Optical Coherence Tomography 3D OCT-1000 Mark II
To collect three dimensional retinal measurements of the optic disc and the macula lutea on healthy normal subjects using the 3D OCT-1000 Mark II for the purpose of developing a normative database that is stratified by age.
- Trial name
- NCT01027936
- Where
- 6 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Topcon Corporation
Glaucoma
Optical Coherence Tomography (OCT) Data Collection Study
Collect OCT data to evaluate the range and age trend of ocular measurements.
- Trial name
- NCT01641835
- Where
- Canada
- Volunteers
- 303 people, healthy volunteers welcome
- Sponsor
- Heidelberg Engineering GmbH