Clinical trials: Optical Coherence Tomography (OCT)
Corneal Transplantation
Intraoperative Optical Coherence Tomography for Ophthalmic Surgical Guidance - Cornea
Optical Coherence Tomography (OCT) image data will be evaluated for image quality and used to test post-processing algorithms to improve detection sensitivity for ophthalmic diseases.
- Trial name
- iOCT-Cornea (NCT05210478)
- Testing
- Optical coherence tomography (OCT)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Vanderbilt University Medical Center
Myopia
The Immediate Effect of Defocus Spectacles On the Choroid Thickness Using Optical Coherence Tomography on Children
The purpose is to examine temporary changes in the subfoveal choroid thickness after removal and after resumed use of Defocus Incorporated Multiple Segment Spectacle Lenses (DIMS).
- Trial name
- TIDOCT (NCT06234189)
- Testing
- Defocus Incorporated Multiple Segment Spectacle Lenses (DIMS)
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- Vejle Hospital
Corneal Dystrophy
Correlation Between In-vivo Anatomy of Corneal Dystrophies as Assessed by High- Resolution Optical Coherence Tomography (OCT) Measurement and Histological Examination
Corneal dystrophies are usually classified histopathologically according to the layer of the cornea that is affected. The International Committee for the Classification of Corneal Dystrophies (IC3D) takes this anatomical…
- Trial name
- NCT03461991
- Testing
- Ultrahigh resolution Spectral Domain OCT
- Where
- 2 sites in Austria
- Volunteers
- 2 people
- Sponsor
- Medical University of Vienna
Retinal Disease
Peripheral Retina Robotically Aligned OCT Study
Optical coherence tomography (OCT) is a 3D imaging technology that has seen wide adoption within ophthalmology. However, optical access to the retinal periphery remains a challenge for conventional OCT systems.
- Trial name
- PR-RAOCT (NCT06451068)
- Testing
- Peripheral retina robotically aligned optical coherence tomography (OCT) system, Likert Scales
- Volunteers
- healthy volunteers welcome
- Sponsor
- Duke University
Diabetic Retinopathy, Periodontitis
Periodontitis Severity in Patients With Diabetic Retinopathy
The aim of this observational study is to investigate the relationship between periodontal disease severity and retinal layer thickness in patients diagnosed with diabetic retinopathy (DR), using optical coherence tomography…
- Trial name
- NCT07137013
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Anterior Clinoid Process Pneumatization, Optic Canal Morphometry
Impact of Anterior Clinoid Process Pneumatization on Optic Canal and Retinal Nerve Fiber Layer
This retrospective cohort study aims to evaluate the potential effects of anterior clinoid process (ACP) pneumatization on optic canal morphometry and retinal nerve fiber layer (RNFL) thickness.
- Conditions
- Anterior Clinoid Process Pneumatization, Optic Canal Morphometry, Retinal Nerve Fiber Layer Thickness
- Trial name
- NCT07451080
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Atherosclerosis, Coronary
Fluid-dynamics in Bifurcation PCI
Investigator-initiated, international, multicentre, observational study with two cohorts. The two study cohorts will be: Cohort A: to understand if the local blood flow patterns (associated with low WSS), as evaluated by…
- Trial name
- FORECAST (NCT03174418)
- Testing
- Coronary angiography and optical coherence tomography
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Catholic University of the Sacred Heart
Macular Hole
Microperimetry and Optical Coherence Tomography (OCT) in Idiopathic Macular Hole
To evaluate the correlations between anatomical and functional changes studied with microperimetry (MPM) and spectral-domain OCT (SD-OCT) in patients after successful repair of idiopathic macular hole (MH).
- Trial name
- NCT01757600
- Testing
- Microperimetry
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Carotid Stenosis, Optical Coherence Tomography (OCT)
Endovascular Treatment of Cerebrovascular Diseases Guided by Optical Coherence Tomography (OCT) Technology（CVD-OCT）
OCT techniques have been used in the assessment of both intracranial and extracranial lesions.(1) Preprocedural evaluation: The morphologic characteristics of carotid atherosclerotic plaques can be evaluated by OCT before surgery…
- Conditions
- Carotid Stenosis, Optical Coherence Tomography (OCT), Endovascular Treatment
- Trial name
- （CVD-OCT) (NCT06986330)
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Tooth Erosion
In Vivo Quantification of Dental Demineralisation Using OCT With and Without Esomeprazole
Dental erosions in 30 male and female patients with proven abnormal gastrooesophageal reflux will be assessed clinically and using a novel optical coherence tomography (OCT) laser technique before and after double-blind…
- Trial name
- NCT00564330
- Testing
- Esomeprazole
- Volunteers
- 30 people
- Sponsor
- Brain-Gut Research Group
High Myopia, Choroid
Effect of Caffeine on Ocular Circulation in High Myopes
To investigate the effect of caffeine on ocular circulation by using Optical Coherence Tomography and Optical Coherence Tomography Angiography.
- Trial name
- NCT03294967
- Testing
- Caffeine, Vitamin E
- Where
- Hong Kong
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Celiac Disease, Healthy
Imaging the Duodenum Using an Optical Frequency Domain Imaging OFDI Capsule
The study is being done to assess the tolerability and feasibility of a tethered OFDI capsule to image the duodenum. A total of 108 participants (36 healthy and 72 with clinically suspected or diagnosed Celiac disease) will be…
- Trial name
- NCT02202681
- Testing
- OFDI Capsule
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Age-related Cataract
Correlation Analysis of Lens Nucleus Density and Surgical Parameters Based on Ss-oct and Scheimpflug Technology
To study the correlation between three different lens nuclear opacity classification methods and intraoperative phacoemulsification parameters .
- Trial name
- NCT05028530
- Where
- China
- Volunteers
- 53 people
- Sponsor
- Wenzhou Medical University
Age Related Macular Degeneration
Correlation Between Visual Field Defects on FORESEE HOME and on Optical Coherence Tomography in Choroidal Neovascularization Subjects
The FORESEE HOME is used in the recent years to detect Age-related Macular Degeneration (AMD) lesions. The device is capable of differentiation as to stages of AMD and early detection of changes including choroidal…
- Trial name
- NCT00884637
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Notal Vision Ltd.
Cardiac Allograft Vasculopathy
Assessment of Cardiac Allograft Vasculopathy With Optical Coherence Tomography
Cardiac allograft vasculopathy (CAV) is a progressive disease of the coronary arteries in transplanted hearts which is a significant cause of morbidity and mortality.
- Trial name
- CAV-OCT-IVUS (NCT01527344)
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Mayo Clinic
Myopia
Optical Coherence Tomography Angiography in Myopic Patients
The aim of this study is to investigate the macular microvascular network alterations in high myopic eyes using optical coherence tomography angiography.
- Trial name
- NCT04135209
- Testing
- Optical coherence tomography angiography OCTA
- Where
- Egypt
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Minia University
Stable Angina, Acute Coronary Syndrome
Novasight Hybrid Intravascular Ultrasound and Optical Coherence Tomography System (IVUS OCT)
Collection of coronary images with a hybrid IVUS OCT system.
- Trial name
- NCT03484975
- Testing
- Observation group
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- Conavi
Coronary Artery Disease, Optical Coherence Tomography
A Single Center Registry of Coronary OCT
This registry started January 1,2020 to collect patients who recieve coronary OCT imaging in Hainan General Hospital.All enrolled patients will receive 1 year followed-up.
- Conditions
- Coronary Artery Disease, Optical Coherence Tomography, Registry
- Trial name
- NCT04855500
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Hainan People's Hospital
Carotid Stenosis
Optical Coherence Tomography Angiography Evaluation of Ocular Changes in Patients With Carotid Artery Stenosis
This study aims to evaluate ocular changes in patients with carotid artery stenosis by optical coherence tomography angiography before and after carotid artery revascularization procedure.
- Trial name
- NCT04326842
- Testing
- Carotid artery revascularization procedure, Optical coherence tomography angiography
- Where
- China
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Stable Angina, Coronary Artery Disease
OCT-Guided Stent Optimization for Short-Duration Dual Antiplatelet Therapy in Stable Angina
This study aims to evaluate whether the use of optical coherence tomography (OCT), an advanced intravascular imaging tool, can improve stent implantation results and make it possible to shorten the duration of dual antiplatelet…
- Trial name
- COMFORT-SHORT (NCT07198529)
- Testing
- Short DAPT, Standard DAPT, Extended DAPT
- Where
- South Korea
- Volunteers
- 130 people
- Sponsor
- Korea University Guro Hospital