Clinical trials: Optical Coherence Tomography Glaucoma
Glaucoma, Diabetic Retinopathy
A Pilot Study of Functional Optical Coherence Tomography for Ocular Imaging
Growing evidence shows that altered blood flow plays a major role in many vision-threatening diseases including glaucoma, diabetic retinopathy, age-related macular degeneration, Central Retinal Vein Occlusion, and Branch Retinal…
- Conditions
- Glaucoma, Diabetic Retinopathy, Age-Related Macular Degeneration, Central Retinal Vein Occlusion
- Trial name
- NCT00556114
- Testing
- Optical Coherence Tomography
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Glaucoma, Angle-Closure
AS-OCT Evaluation of Iridocorneal Angle of Patients of Angle Closure Glaucoma After Phacoemulsification
Evaluation of the effect of phacoemulsification and YAG Laser peripheral iridotomy on the anterior chamber angle anatomic parameters in PACG eyes, using anterior segment optical coherence tomography (SS ASOCT) device
- Trial name
- NCT05332665
- Testing
- AS-OCT, YAG laser PI
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Minia University
Primary Open Angle Glaucoma, Glaucoma
The Objective is to Evaluate the Anterior Chamber Angle After BANG Procedure, the Study Will Recruit 12 Patients Who Will Undergo Planned Goniectomy for Uncontrolled POAG, Anterior Segment OCT Scan Will Be Used to Evaluate the Anterior Chamber Postoperatively.
Evaluation of anterior segment using anterior segment optical coherence tomography in patients undergoing planned bent angle needle goniectomy procedure for uncontrolled open angle glaucoma.
- Trial name
- NCT06526416
- Testing
- Anterior segment optical coherence tomography
- Volunteers
- 12 people
- Sponsor
- Benha University
GLAUCOMA 1, OPEN ANGLE, D (Disorder)
Spectral Domain Optical Coherence Tomography Analysis for Glaucoma
The aim of this study is to examine whether there is a difference in macular ganglion cell complex thickness and retinal nerve fiber layer thickness in early-stage Primary open angle glaucoma and normal tension glaucoma with…
- Trial name
- NCT01612416
- Testing
- RS-3000 OCT measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Inonu University
Glaucoma
SDOCT-GMPE Software
The investigators prospectively evaluate the new glaucoma premium edition (GMPE) software for spectral domain optical coherence tomography (SDOCT) and if this software is superior to the conventional one that is currently used…
- Trial name
- NCT02235454
- Testing
- SDOCT-GMPE software
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Duke University
Glaucoma, Open-Angle
The Effect of Pseudoexfoliation on Choroidal Thickness in Open Angle Glaucoma
Purpose: To investigate the effect of pseudoexfoliation (PEX) on choroidal thickness in primary open-angle glaucoma (POAG). Methods: This prospective, randomized study included 30 POAG patients and 30 PEX glaucoma patients with…
- Trial name
- NCT03373942
- Testing
- Choroidal thickness measurements with SD-OCT device
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Emine Deniz Egrilmez
Obstructive Sleep Apnea, Hypopnea Syndrome
Retinal Nerve Fiber Layer Thickness Measurements in Patients With Sleep Apnea Syndrome
The purpose of this study was to measure the retinal nerve fiber layer (RNFL) thickness in eyes of Obstructive Sleep Apnea/hypopnea syndrome (OSAHS) using optical coherence tomography (OCT), and assess whether it is decreased.
- Conditions
- Obstructive Sleep Apnea, Hypopnea Syndrome, Glaucoma
- Trial name
- NCT01188291
- Where
- Israel
- Volunteers
- 166 people
- Sponsor
- Carmel Medical Center
Meibomian Gland Dysfunction, Cataract
Ultrahigh-resolution Optical Coherence Tomography Imaging of the Anterior Eye Segment Structures
The development of optical coherence tomography (OCT) and its application for in vivo imaging has opened entirely new opportunities in ophthalmology.
- Conditions
- Meibomian Gland Dysfunction, Cataract, Glaucoma, Corneal Transplantation
- Trial name
- NCT03461978
- Testing
- Ultrahigh resolution Spectral Domain OCT
- Where
- Austria
- Volunteers
- 14 people
- Sponsor
- Medical University of Vienna
Glaucoma
Functional and Structural Imaging for Glaucoma
The specific aims of the clinical studies are to: Develop a directional high-resolution OCT and OCT angiography prototype to improve imaging of structure and perfusion.
- Trial name
- FSOCT (NCT01957267)
- Where
- United States
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Uveitis, Glaucoma
Assessment of Retinal Nerve Fibre Layer by Optical Coherence Tomography in Uveitis Patients With Papilloedema
Assessment of optic disc morphology can be difficult in patients with uveitis and papilloedema. Therefore different optical coherence tomography (OCT) and laser scanning techniques may help to detect damage to the retinal nerve…
- Trial name
- NCT01170481
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- St. Franziskus Hospital
Normal Subject, Glaucoma
Assessment of an Automated Optical Coherence Tomography and Camera : Effectiveness of Vision-700
The objective of study is to assess the repeatability and agreement of the retina and cornea measurement by Vision-700 in comparison with those by 3D OCT-1.
- Conditions
- Normal Subject, Glaucoma, Retinal Disease, Cornea
- Trial name
- NCT06496763
- Testing
- Vision-700
- Where
- Taiwan
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Crystalvue Medical Coporation
Treatment Outcome
Effect of Latanoprost on Optic Nerve Perfusion
46 eyes of 23 patients have been treated with topical Latanoprost 0.005 %. visual field was performed on all eyes. NFLT was measured using OCT. Radial peripapillary capillary (RPC) vascular density was measured using OCTA .
- Trial name
- NCT06629129
- Testing
- Latanoprost (0.005%)
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Zagazig University
Glaucoma Secondary, Congenital Cataract
Quantitatively Analysis of Fundus Structure Characteristics in Glaucoma Following Congenital Cataract Surgery
To quantitatively analyze the fundus structure and microvascular characteristics of GFCS and non-GFCS (NGFCS) using optical coherence tomography angiography (OCTA), to explore the vascular-structural association, and to assess…
- Trial name
- NCT05446077
- Where
- China
- Volunteers
- 129 people
- Sponsor
- Sun Yat-sen University
Primary Open Angle Glaucoma, Pseudoexfoliative Glaucoma
Advanced Glaucoma Progression Study
Glaucoma is one of the leading causes of blindness in the world. The key to prevention of visual loss from glaucoma is early detection of the disease or its progression and timely treatment.
- Conditions
- Primary Open Angle Glaucoma, Pseudoexfoliative Glaucoma, Chronic Angle Closure Glaucoma
- Trial name
- AGPS (NCT01742819)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of California, Los Angeles
Glaucoma, Retinal Disease
Nidek RS3000 Comparative Study
The primary objective of this clinical study is to compare the Nidek RS-3000 Optical Coherence Tomography (OCT) device to the Optovue RTVue OCT.
- Conditions
- Glaucoma, Retinal Disease, Corneal Disease
- Trial name
- NCT01384487
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Nidek Co. LTD.
Glaucoma, Primary Open Angle, Ocular Blood Flow
The Effect of Topical Brimonidine on the Ocular Hemodynamics in Patients of POAG Using OCTA
Topical Brimonidine is a well-established topical antigalucoma, ocular hypotensive therapeutic that has been in use since 1996. Brimonidine stands out among other topical ocular hypotensives in that it has a neuroprotective…
- Conditions
- Glaucoma, Primary Open Angle, Ocular Blood Flow, Optical Coherence Tomography Angiography
- Trial name
- NCT05474716
- Testing
- Brimonidine tartrate 0.2% ophthalmic solution
- Where
- Egypt
- Volunteers
- 41 people
- Sponsor
- Fayoum University
Glaucoma, Retinal Disease
OCT Agreement and Crossed Precision Study
The purpose of this study is to asses the agreement of the RS-3000 Lite and RS-3000 Advance to the RS-3000, assess the crossed precision of each study device and to assess the transference of a reference database from the RS-3000…
- Conditions
- Glaucoma, Retinal Disease, Corneal Disease
- Trial name
- NCT02050880
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Nidek Co. LTD.
Glaucoma, GLAUCOMA 1, OPEN ANGLE, D (Disorder)
Optical Coherence Tomography Findings Associated With the Glaucoma-periodontitis Stage
The aim of this observational study is to investigate the relationship between the stage of periodontal disease and retinal layer thicknesses in glaucoma patients using optical coherence tomography (OCT).
- Conditions
- Glaucoma, GLAUCOMA 1, OPEN ANGLE, D (Disorder), Periodontitis
- Trial name
- NCT07853469
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Retinal Disease, Glaucoma
Optimize Pediatric OCT Imaging
Handheld optical coherence tomography (OCT) has become an important imaging modality to evaluate the pediatric retina. The objective of this pilot study is to compare a new contact OCT system (Theia Imaging) with an…
- Conditions
- Retinal Disease, Glaucoma, Optic Nerve Diseases
- Trial name
- NCT06139523
- Testing
- Investigational contact OCT system, Investigational noncontact OCT system:
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Duke University
Retinal Disease, Glaucoma
Topcon 3D OCT-1000 Optical Coherence Tomography System
The purpose of this clinical protocol is to perform a comparison of Retinal and Retinal Nerve Fiber Layer (RNFL) thickness measurements between the Topcon 3D-1000 and the identified predicate device.
- Trial name
- NCT00792259
- Where
- 4 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Topcon Medical Systems, Inc.