Clinical trials: Oral
Candidiasis, Oral
CelAgace™ OraRinse Solution for Treatment of Candidiasis
CelAgace™ OraRinse (silver citrate complex and acemannan) Solution is planned to be evaluated for safety and effectiveness as a potential treatment for candidiasis, a yeast infection, commonly known as thrush, which is associated…
- Trial name
- NCT03250923
- Testing
- silver citrate complex and acemannan
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- CelaCare Technologies, Inc.
Nasopharyngeal Carcinoma, Radiation-induced Oral Mucositis
Bacterial Decolonization to Prevent Radiation-induced Oral Mucositis
The purpose of this study is to determine whether bacterial decolonization of the nares prior to treatment with radiotherapy (RT) for patients with nasopharyngeal carcinoma, can prevent high-grade radiation-induced oral mucositis…
- Conditions
- Nasopharyngeal Carcinoma, Radiation-induced Oral Mucositis, Bacterial Colonization, Quality of Life
- Trial name
- NCT05893810
- Testing
- Mupirocin Ointment
- Where
- China
- Volunteers
- 176 people
- Sponsor
- Jiangxi Provincial Cancer Hospital
Blood Stem Cell Transplant Failure, Oral Mucositis
The Effect of Nursing Education on Oral Mucositis in Bone Marrow Transplant Patients
In this study, it is aimed to examine the effect of oral care training for oral mucositis, which will be given by the researcher to patients who have undergone bone marrow transplantation, on the incidence and severity of oral…
- Conditions
- Blood Stem Cell Transplant Failure, Oral Mucositis, Nurse's Role
- Trial name
- NCT05705622
- Testing
- Oral mukositis nurse's education for patients
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Antalya Training and Research Hospital
Gingival Recession, Surgery
Analysis of Root Coverage Stability.
One-hundred and one healthy participants (221 gingival recessions-GRs) were treated from 1987 to 1996. The probing depth (PD), keratinized tissue width (KTW), gingival recession depth (RD), gingival recession width (RW), gingival…
- Conditions
- Gingival Recession, Surgery, Oral Disease
- Trial name
- NCT05439382
- Testing
- Gingival recession regenerative surgery
- Where
- Italy
- Volunteers
- 101 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Dental Phobia, Dental Anxiety
The Impact of Medical Play in the Dental Clinic Setting on the Cooperation of Neurotypical Patients
The purpose of this pilot study is to investigate the efficacy of medical play in the dental setting to improve the behaviors and cooperation of neurotypical patients during dental visits.
- Conditions
- Dental Phobia, Dental Anxiety, Oral Aversion
- Trial name
- NCT05571423
- Testing
- Medical Play, Routine Play
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Oral Lichen Planus
Topical Erythropoietin Hydrogel in Management of Oral Lichen Planus
The purpose of this study is to compare the clinical efficacy of erythropoietin gel containing a solution of 4000 units with triamcinolone acetonide 0.1% gel in the treatment of symptomatic oral lichen planus (OLP)
- Trial name
- NCT06135259
- Testing
- erythropoietin, Triamcinolone acetonide
- Volunteers
- 18 people
- Sponsor
- Ain Shams University
Asthma, Candidiasis, Oral
Study to Assess the Incidence of Local Oropharyngeal and Laryngeal Adverse Effects of Advair DISKUS 250/50 mcg BID
This Pilot study is designed to explore the rate of local side effects of fluticasone as delivered by Advair and to determine the best outcome measure to assess these effects.
- Conditions
- Asthma, Candidiasis, Oral, Voice Disorders
- Trial name
- NCT00235053
- Testing
- fluticasone/salmeterol DISKUS 250/50
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Allergy & Asthma Medical Group & Research Center
Squamous Cell Carcinoma of the Oral Cavity
IRX-2 Regimen in Patients With Newly Diagnosed Stage II, III, or IVA Squamous Cell Carcinoma of the Oral Cavity
The purpose of this study is to determine whether a pre-operative regimen of the study drug, IRX-2, a human cell-derived biologic with multiple active cytokine components, plus a single dose of cyclophosphamide, followed by 21…
- Trial name
- INSPIRE (NCT02609386)
- Testing
- IRX-2, Cyclophosphamide, Indomethacin
- Where
- 22 sites in United States, Brazil and 2 more
- Volunteers
- 105 people
- Sponsor
- Brooklyn ImmunoTherapeutics, LLC
Oral Health, Surveys and Questionnaires
Translation and Validation of the Arabic Version of the OHIP Questionnaire
OHIP questionnaire was originally developed in English and in order to make use of this tool to measure the oral health-related quality of life of elderly Arabic populations, A translation is necessary.
- Trial name
- NCT05751902
- Testing
- Arabic version of OHIP questionnaire
- Where
- 2 sites in Egypt
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Surgery, Oral, Hemorrhage
NOACs in Oral and Maxillofacial Surgery: Impact on Post-operative Complications
Aims: To investigate the incidence of bleeding complications during oral surgical procedures in patients medicated with DOACs. To investigate the perioperative and postoperative bleeding volume during oral surgical procedures in…
- Conditions
- Surgery, Oral, Hemorrhage, Postoperative Complications, Oral Surgical Procedures
- Trial name
- NCT04662515
- Testing
- Type of surgery, Dabigatran, Rivaroxaban
- Where
- 2 sites in Sweden
- Volunteers
- 216 people
- Sponsor
- Malmö University
Oral Cavity Cancer
Efficacy of Swallowing Function After Early Postoperative Oral Exercise Among Patient With Oral Cavity Cancer Underwent Flap Reconstruction
Efficacy of swallowing function after early postoperative oral exercise among patient with oral cavity cancer underwent flap reconstruction: A randomized controlled trial
- Trial name
- NCT05056064
- Testing
- Oral exercise
- Where
- Thailand
- Volunteers
- 90 people
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Cancer of Head and Neck, Mucositis Oral
Efficacy of Ketamine Mouthwash in the Management of Oral and Pharyngeal Toxicity Associated With Head and Neck Chemoradiotherapy: A Phase 2, Simon 2-stage Trial
Patients with head and neck cancer generally receive a standard of care of 7 weeks of daily radiation therapy given alongside an aggressive chemotherapy drug called cisplatin.
- Conditions
- Cancer of Head and Neck, Mucositis Oral, Pharyngeal Mucositis
- Trial name
- NCT05331131
- Testing
- Ketamine Topical
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwell Health
Oral Health, Prisoners
Oral Health in Prison: a Study on Improving Prisoners' Oral Health
This study investigates the effects of an intervention based on Motivational Interviewing (MI) on oral hygiene, oral cleaning routines, and attitudes toward own oral health of prisoners in Norway.
- Trial name
- NCT05695443
- Testing
- Motivational Interviewing
- Where
- Norway
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Oral Health Center of Expertise Rogaland, Norway
Chemotherapy Induced Oral Mucositis
Low Level Diode Laser Versus Topical Chamomile in Management of Chemotherapy Induced Oral Mucositis
a three-arm head-to-head randomized clinical trial assessing two of the promising studied interventions, low-level diode laser and topical Chamomile, comparing them to each other's and to conventional therapy in the management of…
- Trial name
- NCT06214273
- Testing
- Low level diode laser, Chamomile, Ibuprofen analgesic and anti-inflammatory oral gel and miconazole anti fungal oral gel
- Volunteers
- 45 people
- Sponsor
- Cairo University
Oral Potentially Malignant Lesions
Cathelicidin LL-37 Relation to Potentially Malignant Lesions
LL-37 appears to have a potential role in potentially malignant lesions (OLP \& leukoplakia). The remarkable diagnostic accuracy of salivary LL-37 in differentiating potentially malignant lesion and healthy control could confirm…
- Trial name
- NCT06219330
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Mucositis Oral
Evaluation of Prophylactic Photobiomodulation Therapy in Patients With Osteosarcoma
This study aims to evaluate the photobiomodulation therapy (PBMT) for the prevention of oral mucositis in osteosarcoma patients submitted to high doses of methotrexate, through two different protocols.
- Trial name
- PBMT/MTX (NCT06217224)
- Testing
- Preventive photobiomodulation Therapy (PBMT)
- Where
- Brazil
- Volunteers
- 53 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Clinical CT Abdomen/Pelvic With Oral Contrast and Sedation
CT Residual Gastric Fluid Volume
Hypothesis: The investigators hypothesize that more than 50% of the patients receiving enteric contrast material (ECM) < 2 hours of anesthesia/sedation would have residual gastric fluid volume (GFV) > 0.4 ml/kg.
- Trial name
- NCT02239068
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
TMJ - Oral &Maxillofacial Surgery
Computer Guided Versus Conventional Arthrocentesis in Management of Internal Derangements: A Randomized Clinical Study
The aim of the study is to evaluate the applicability, accuracy, benefits and the efficacy of 3-dimensional, printed, patient-specific guides to direct TMJ access for arthrocentesis when performed in contrast with conventional…
- Trial name
- NCT06205667
- Testing
- Computer Guided Arthrocentesis, Conventional Arthrocentesis
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Preterm Neonates and Feeding Intolerance, Necrotizing Enterocolitis
Effect of Oral N-Acetyl Cysteine in Prevention of Necrotizing Enterocolitis in Preterm Neonates With Feeding Intolerance
necrotizing enterocolitis is a dangerous disease that may be fatal especially in preterm neonates, the early features of the disease are symptoms of feeding intolerance and interruption of the baby's feeding plan , so…
- Conditions
- Preterm Neonates and Feeding Intolerance, Necrotizing Enterocolitis, Oral N-acetyl Cysteine
- Trial name
- Oral NAC (NCT06202911)
- Testing
- oral n-acetyl cysteine
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Oral Lichen Planus, Vitamin D Deficiency
The Role of Vitamin D in Amelioration of Oral Lichen Planus and Its Effect on Salivary IFN-γ Level
The goal of this clinical trial is to compare between the use of vitamin D supplement in conjunction with systemic steroids versus the use of systemic steroids alone in the management of patients with symptomatic Oral Lichen…
- Trial name
- NCT06204796
- Testing
- vitamin D supplement was given as 60,000 IU weekly in conjunction with systemic prednisone, Systemic prednisone
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Fayoum University