Clinical trials: Oral Cancer Screening
Xerostomia Due to Radiotherapy (Disorder)
Screening of Biomarkers and Related Mechanisms for RIX
A large number of patients undergoing radiotherapy and chemotherapy are suffering from dry mouth. Due to reduced saliva secretion, patients may experience symptoms such as difficulty chewing and swallowing.
- Trial name
- RIX (NCT06700863)
- Testing
- Radiation Therapy
- Where
- 4 sites in China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Salivary Gland Cancer, Adenoid Cystic Carcinoma of the Salivary Gland
Drug Screening Using Novel IMD in Salivary and Head and Neck Cancers
This research study is studying the effect of different drugs as possible treatments for salivary and other head and neck cancers/ The name of the study intervention involved in this study is: -- implantable microdevice
- Conditions
- Salivary Gland Cancer, Adenoid Cystic Carcinoma of the Salivary Gland, Squamous Cell Carcinoma of Head and Neck, Head and Neck Cancer
- Trial name
- NCT05553782
- Testing
- Implantable Microdevice (IMD)
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Brigham and Women's Hospital
Oral Cancer, Diagnoses Disease
Exfoliated Cytology in Detection of Oral Premalignant and Malignant Lesions
Micronuclei have been used since 1937 as an indicator of genetic toxic exposure due to their association with chromosomal alterations.
- Trial name
- NCT04955197
- Testing
- exfoliated cytology
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Oral Cancer, Precancerous Conditions
Oral Cancer Screening in Mumbai, India by Primary Health Care Workers
A feasibility study to compare the test characteristics of three different oral cancer screening techniques performed by trained primary health care workers:1)Unaided Visual Inspection, 2)VelScope Assisted Examination, and 3)…
- Trial name
- NCT00655421
- Testing
- Unaided Visual Inspection, VelScope, Toluidine Blue Assisted Oral Examination
- Where
- India
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- Tata Memorial Hospital
Pain, Cancer
A Phase 2a, Proof-of-Concept Study of GIC-1001 in the Management of Visceral Pain During Sedation-Free, Full Colonoscopy
GIC-1001 is a novel, orally-administered, colonic analgesic drug developed as an alternative to i.v. sedation during full colonoscopy.
- Conditions
- Pain, Cancer, Colonic Diseases
- Trial name
- NCT01926444
- Testing
- GIC-1001
- Where
- 15 sites in United States, Canada
- Volunteers
- 308 people
- Sponsor
- gicare Pharma Inc.
Malignant Neoplasms of Mesothelial and Soft Tissue, Human Immunodeficiency Virus
Non Invasive Oral Cancer Screening Among HIV Infected Individuals
The goal of this clinical research study is to learn how a new method for performing oral (mouth) exams can help doctors check for suspicious lesions (called premalignant and malignant oral lesions [PMOL]) in the mouth of…
- Trial name
- NCT02823847
- Testing
- Screening Interview, Carbon Monoxide Test, Self-Help Materials
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- M.D. Anderson Cancer Center
Oral Cancer
Oral Cancer Screening in Workplace: a Cross-sectional Study
Employees are to be all screened for oral cancer in work place.
- Trial name
- NCT06057857
- Testing
- conventional oral examination
- Where
- Egypt
- Volunteers
- 302 people
- Sponsor
- Cairo University
Cervical Cancers, Breast Cancer
Effectiveness and Impact of the Lived Experience Cancer Awareness Campaign on Screening Participation
This study will be conducted as a parallel-arm, open-label, randomized controlled trial (RCT) to evaluate the effectiveness and impact of the Lived Experience Communication Campaign (LECC) on cancer screening participation rates…
- Conditions
- Cervical Cancers, Breast Cancer, Oral Cancer
- Trial name
- NCT06874985
- Testing
- Lived experience video campaign
- Where
- India
- Volunteers
- 1,264 people, healthy volunteers welcome
- Sponsor
- International Agency for Research on Cancer
Premalignant Lesion, Oral Cancer
Diagnostic Accuracy of Mobile Phone Imaging Compared to Conventional Clinical Examination for Oral Cancer Screening
The aim of study is to evaluate the sensitivity and specificity of using mobile phone photographs versus conventional clinical examination as a screening tool for early detection of oral cancer.
- Trial name
- NCT06060288
- Testing
- Diagnosis by mobile phone imaging
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Cairo University
Breast Cancer, Endometrial Cancer
BI 2536 in Treating Patients With Recurrent or Metastatic Solid Tumors
RATIONALE: BI 2536 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. PURPOSE: This phase II trial is studying the side effects and how well BI 2536 works in treating patients with…
- Conditions
- Breast Cancer, Endometrial Cancer, Head and Neck Cancer, Melanoma (Skin)
- Trial name
- NCT00526149
- Testing
- BI 2536, high performance liquid chromatography, mass spectrometry
- Where
- Belgium
- Volunteers
- 76 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Colorectal Cancer, Periodontitis
Fusobacterium Nucleatum at Colorectal Cancer Sites
Recent studies suggest an association of periodontitis with an overall increased cancer risk but also with cancer development in specific anatomic regions, such as in the colon.
- Trial name
- NCT05945082
- Testing
- biopsy
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Malmö University
Pancreatic Cancer
Using Digestive Microbial Information to Enhance the Early Detection of Pancreatic Cancer
Pancreatic cancer (PCA) is a leading death-related cancer. There is an urgent need for accurate, noninvasive diagnostic options in the early detection of pancreatic cancer (PCA), since delayed diagnosis increases the risk of…
- Trial name
- NCT05689138
- Testing
- Oral and Fecal Sample Collection
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Oral Precancer, Oral Cancer
Evaluation of Two Non-Invasive Methods, High-Resolution Microendoscopy and Liquid-Based Cytology, for Detection of Oral Precancer
Cancers of the oral cavity (lip, oral tongue, gingivae, floor of mouth, hard palate, and other mouth tissues including buccal mucosa) are amongst the most common worldwide, with an estimated annual burden of over 300,000 incident…
- Conditions
- Oral Precancer, Oral Cancer, Oral Cancer Screening
- Trial name
- NCT07260344
- Testing
- High-resolution microendoscopy of visible oral precancerous lesions, Standard of care
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- Anil Chaturvedi
Head and Neck Cancer
Diagnostic Aids for Detection and Diagnosis of Oral Cancer
The goal of this clinical study is to find out if certain instruments/devices, such as wide field fluorescence imaging point spectroscopy and/or brush cytology, can help health care providers find mouth cancer more quickly than a…
- Trial name
- NCT02251639
- Testing
- Questionnaire, POS + PS2 + VELscope, Oral Brush Biopsy
- Volunteers
- healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Oral Cancer, Oral Cavity Cancer
Low-cost Screening and Image-guided Photodynamic Therapy (PDT) of Premalignant and Malignant Oral Lesions
The primary goal of this study is to see if photodynamic therapy (PDT) is effective for treatment of lesions in the oral cavity which have high risk of becoming oral cancer.
- Conditions
- Oral Cancer, Oral Cavity Cancer, Oral Leukoplakia, Oral Lichen Planus
- Trial name
- NCT06876038
- Testing
- 5-Amino Levulinic Acid
- Where
- 2 sites in India
- Volunteers
- 65 people
- Sponsor
- University of Massachusetts, Boston
Colorectal Cancer, Malnutrition or Risk of Malnutrition
The Role of Arginine in Oral Nutritional Supplementation in Preventing or Reducing Complications Following Colorectal Surgery in Patients Who Are Malnourished or at Risk of Malnutrition
The goal of this randomized controlled trial is to evaluate the role of a high-calorie, high-protein oral nutritional supplement enriched with arginine in the prevention or reduction of post-surgical complications in adult…
- Conditions
- Colorectal Cancer, Malnutrition or Risk of Malnutrition, Colorectal Surgery
- Trial name
- NCT07506187
- Testing
- Diaba plus®: A high-protein, high-calorie ONS with no generic equivalent, Atémpero®: An ONS enriched with arginine with no generic equivalent
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- University of Cadiz
Head and Neck Cancer
Oral Cancer Screening Among Nursing Home Dentists in Ohio
RATIONALE: Learning about oral cancer screening practices, knowledge, and opinions of Ohio nursing home dentists may help the study of oral cancer in the future.
- Trial name
- NCT00526851
- Testing
- survey administration
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Mouth Neoplasms
Oral Cancer Screening for Early Detection of Premalignant Disorders (PMOD)
Cancer is a complex disease; its different causes and types have a strong impact on patient treatment and prognosis. To improve understanding of the disease, its causes and progression, the investigators will develop a simple…
- Trial name
- PMOD (NCT05296941)
- Testing
- Brush sampling
- Where
- Sweden
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Dalarna County Council, Sweden
Tobacco Cessation, Oral Cancer
Workplace Tobacco Cessation And Oral Cancer Screening Study
Tata Memorial Hospital has initiated Workplace Tobacco Cessation and Oral Cancer Screening Programme in Chemical Industry at Khed, Ratnagiri.
- Trial name
- NCT00750503
- Testing
- Behavioural and Pharmacotherapy for tobacco cessation
- Where
- India
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Tata Memorial Hospital
Oral Cancer Screening
Non-invasive Methods for Oral Cancer Screening
Oral cancer is a common cancer worldwide, with approximately 250,000 new cases annually and a high mortality rate. Its major risk factors include smoking, alcohol consumption, and betel nut chewing.
- Trial name
- HRME (NCT07249437)
- Where
- Taiwan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital