Clinical trials: Oral Dysesthesia
Acquired Immunodeficiency Syndrome, Burning Mouth Syndrome
Thalidomide to Treat Oral Lesions in HIV-Infected Patients
This study will test the effectiveness of topical thalidomide in healing mouth sores in HIV infected patients. Oral (PO) thalidomide heals these sores at a dose of 200 mg per day.
- Conditions
- Acquired Immunodeficiency Syndrome, Burning Mouth Syndrome, HIV Infection
- Trial name
- NCT00001524
- Testing
- Thalidomide
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Burning Mouth Syndrome
Impact of Alpha Lipoic Acid Efficacy in Burning Mouth Syndrome
A double-blind placebo-controlled trial is conducted in order to evaluate the efficacy of alpha lipoic acid (ALA) and determine the statistical significance of the outcome variables.
- Trial name
- NCT05729529
- Testing
- Lipoid acid gel
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Catania
Pain
Assessment of Peripheral GABA Receptors for Local Pain Relief
The effect of peripheral GABAA receptor activation on pain and sensitivity in healthy human subjects has never been investigated.
- Trial name
- NCT02928328
- Testing
- GABA oral solution, Intramuscular GABA, Pain modulation
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Primary Burning Mouth Syndrome
Identification of Pathophysiological Pathways and Therapeutic Targets in Primary Stomatodynia by Salivary Metabolomics
Burning mouth syndrome (BMS) is defined by a chronic oral pain affecting especially postmenopausal women. Its physiopathology is still unknown and several hypotheses have been put forward to explain this syndrome, such as…
- Trial name
- SESAME (NCT04704128)
- Testing
- Salivic sample
- Where
- France
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Burning Mouth Syndrome, Glossodynia
Evaluation of the Effectiveness of the Selected Method of Treatment of Primary Burning Mouth Syndrome
The burning mouth syndrome (BMS) is a chronic pain syndrome of the oral mucosa. Feels like experiencing a burning sensation, pain, stinging, or numbness in the mouth along with a feeling of dryness, paraesthesia, taste…
- Trial name
- NCT04884503
- Testing
- Clonazepam tablets, tongue pads
- Where
- Poland
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Burning Mouth Syndrome, Progesterone
Hormonal Status and Quality of Life in Female Postmenopausal Patients With Burning Mouth Syndrome
The aim of this study was to determine the level of salivary estradiol, progesterone and dehydroepiandrosterone in female postmenopausal women with and without burning mouth syndrome.
- Conditions
- Burning Mouth Syndrome, Progesterone, Dehydroepiandrosterone, Quality of Life
- Trial name
- NCT04535973
- Testing
- unstimulated saliva sample for hormone analysis, quality of life questionnaire
- Where
- Croatia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Burning Mouth Syndrome
Comparison Between Two Treatments for Burning Mouth
Introduction: The management of patients with chronic burning mouth is a challenge in clinical dentistry. Objective: To compare the effect of Low Level Laser Therapy (LLLT) and Transcutaneous Electrical Nerve Stimulation (TENS)…
- Trial name
- NCT05816200
- Testing
- Low-Level Light Therapy, Transcutaneous Electric Nerve Stimulation
- Where
- Brazil
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Primary Burning Mouth Syndrome (BMS)
Theravex® for Burning Mouth Syndrome
In this randomized, double-blind, placebo-controlled trial, 116 adults with primary BMS were assigned (1:1) to receive THERAVEX® Total Oral Care Plus or placebo for 8 weeks.
- Trial name
- NCT07564843
- Testing
- THERAVEX® Total Oral Care Plus
- Where
- Egypt
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Biointelligent Technology Systems SL
Burning Mouth Syndrome
Neurogenic Mechanisms in Burning Mouth Syndrome
Burning mouth syndrome (BMS) is characterized by a bilateral burning sensation in the anterior tongue, hard palate and lips in the absence of any clinical or laboratory findings.
- Trial name
- BMS17 (NCT00875537)
- Testing
- Capsaicin oral gel 0.025%, Capsaicin oral gel 0.01%
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Burning Mouth Syndrome
Therapeutic Options for Treatment of Burning Mouth Syndrome
Burning mouth syndrome is a painful condition of unknown etiology that impairs the quality of life and does not have an adequate therapeutic option.
- Trial name
- NCT04475614
- Testing
- BioGaia Prodentis lozenges, low level laser treatment with Ga-Al-As laser, B vitamin injections (Neurobion, Merck, Darmstadt, Germany)
- Where
- Croatia
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Burning Mouth Syndrome
Impact of Diazepam 1% Oral Gel Efficacy in Burning Mouth Syndrome
Burning mouth syndrome (BMS) is a syndrome characterized by burning and persistent oral pain, ranging from mild to intense, in the absence of organic disorders of the oral cavity and with a major impact on the quality of life of…
- Trial name
- NCT05872789
- Testing
- Diazepam 1% oral gel
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Catania
Burning Mouth Syndrome
Low Level Laser Therapy Plus Topical Clonazepam Treatment to Burning Mouth Symdrome
Burning mouth syndrome (BMS) is a condition that affects the oral mucosa; this is seen mainly in postmenopausal women. The intensity of burning and its clinical manifestations may be variable between patients.
- Trial name
- BurnLasCLo (NCT04313907)
- Testing
- low level laser therapy plus topical clonazepam
- Where
- Mexico
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Mexico
Burning Mouth Syndrome
Study Evaluating the Laser Diode Effect Burning Mouth Syndrome
The aim of this study was to report the effect of laser diode on the treatment of burning mouth syndrome (BMS) Patients were randomly allocated to two different groups: the first one (group A) underwent Laser diode whereas the…
- Trial name
- laser (NCT02757612)
- Testing
- laser diode
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Burning Mouth Syndrome
Opiorphin Levels in Fluids of Burning Mouth Syndrome Patients (OPIODYN)
If epidemiological studies indicate relatively low prevalence reported in the general population, idiopathic burning mouth syndrome (BMS) is a common condition among certain groups of the population: 30% of menopausal women…
- Trial name
- OPIODYN (NCT02686359)
- Testing
- sample
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Burning Mouth Syndrome, Quality of Life
Effect to the Photobiomodulation in the Burning Mouth Syndrome
Introduction: Burning mouth syndrome (BMS) is a pathology with a low prevalence, affecting between 0.1% and 3.7% of the general population, the ratio between women and men is between 3 and 7:1.
- Conditions
- Burning Mouth Syndrome, Quality of Life, Anxiety Depression, Dry Mouth
- Trial name
- PBM-BMS (NCT05871580)
- Testing
- Low frequency laser activated photobiomodulation, Low frequency laser photobiomodulation inactive
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Sleep Disorders, Circadian Rhythm
The Efficacy of Melatonin in the Burning Mouth Syndrome
Burning mouth ( BMS) syndrome is the oral disorder characterized by an intraoral burning sensation for which no medical or dental cause can be found.
- Trial name
- BMS (NCT03788733)
- Testing
- Melatonin 3 mg
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Burning Mouth Syndrome
Effectiveness of Mucolox® and Clonazepam in Treatment of Burning Mouth Syndrome
What affect does the use of a mucoadhesive drug delivery system (Mucolox®) compounded with clonazepam have in the treatment of burning mouth syndrome? There are no clinical trials reported in the literature that evaluate the use…
- Trial name
- NCT02690844
- Testing
- Clonazepam mixed with Mucolox®, Mucolox® alone, Clonazepam
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alberta