Clinical trials: Oral Epithelial Dysplasia (OED)
Oral Epithelial Dysplasia (OED), Oral Squamous Cell Carcinoma (SCC)
Evaluating Treatment Strategies for p53 Mutant Oral Cancer and Oral Cancer Precursors
The goal of this clinical trial is to optimize treatment strategies for patients with p53-mutant oral epithelial dysplasia (OED) and early-stage oral squamous cell carcinoma (OSCC).
- Trial name
- p53 RCT (NCT07090070)
- Testing
- Cohort 1 Intervention group, Cohort 2 severe/CIS margins clear, Cohort 2 p53 and severe/CIS margins clear
- Where
- Canada
- Volunteers
- 636 people
- Sponsor
- University of British Columbia
Oral Epithelial Dysplasia (OED)
CAN1012 in Pre-malignant Oral Dysplasia
The primary objective of this trial is to examine the safety of CAN1012 delivered by intralesional injection ahead of planned surgical resection.
- Trial name
- NCT07620496
- Testing
- CAN1012
- Volunteers
- 36 people
- Sponsor
- Providence Health & Services