Clinical trials: Oral Health Related Quality of Life
Malocclusion, Crossbite
Evaluation of Removable Appliances and Clear Aligners in Early Orthodontic Treatments During the Mixed Dentition Period
This prospective study aims to compare two different orthodontic treatment modalities-clear aligners and removable appliances-in children aged 6 to 12 years during the mixed dentition period.
- Trial name
- NCT07331090
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Neslihan Atmaca
Dentinogenesis Imperfecta, Amelogenesis Imperfecta
Psycho-social Impact of Amelogenesis and Dentinogenesis Imperfecta
The purpose of this research is to study the impact of dentinogenesis (DI) and amelogenesis (AI) imperfecta on oral quality of life, exposure to bullying and dental anxiety in a population of adolescents.
- Trial name
- AiDiBull (NCT04927962)
- Testing
- Questionnaires
- Where
- 7 sites in France
- Volunteers
- 87 people
- Sponsor
- University Hospital, Toulouse
Cancer, Cancer, Treatment-Related
Oncotool for Cancer Medications
The purpose of this study is to examine the efficacy of a psychosocial eHealth intervention on the proposed primary outcomes, TKI adherence and health related quality of life (HRQoL), in patients taking TKIs for cancer…
- Conditions
- Cancer, Cancer, Treatment-Related, Medication Adherence, Communication
- Trial name
- NCT03952312
- Testing
- Oncotool Intervention (symptom reporting + TKI education), Oncotool Control (health information)
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Northwestern University
Food Hypersensitivity, Immune System Diseases
Oral Immunotherapy in Food Allergy in Finland
The outcomes of oral immunotherapy (OIT) in food allergy study will provide more knowledge of oral immunotherapy. So far the OIT has showed in clinical experiments to be a interesting way to increase the unresponsiveness in…
- Conditions
- Food Hypersensitivity, Immune System Diseases, Anaphylaxis
- Trial name
- NCT02640014
- Testing
- Milk
- Where
- Finland
- Volunteers
- 250 people
- Sponsor
- Helsinki University Central Hospital
Head and Neck Cncer
Oral Health-Related Quality of Life Using EORTC QLQ-H&N35 in Head and Neck Cancer Survivors Within the First Year Following Treatment: a Cross-Sectional Study in Egypt
This study aims to evaluate Oral Health-Related Quality of Life (OHRQoL) in head and neck cancer (HNC) survivors within the first year following treatment in Egypt.
- Trial name
- NCT06901401
- Where
- Egypt
- Volunteers
- 112 people
- Sponsor
- Ain Shams University
Maxillary Deficiency, Head and Neck Neoplasms
Predictors of Patient-Reported Outcomes for Maxillectomy Patients
The success of digitally fabricated obturator rehabilitation is determined not only by the prosthesis itself but also by the interaction between patient characteristics, oncologic history, prosthetic support, and…
- Trial name
- NCT07864974
- Testing
- Digitally Fabricated Obturator Prosthesis
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Dr. Merve Benli
Dental Caries
Clinical and Radiographic Assessment of First Permanent Molars With Cention-N
: Assessment of Clinical, Radiographic, and Oral Health-Related Quality of Life Following Restoration of First Permanent Molars with Cention N: A 12-Month Split-Mouth Randomized Controlled Trial Introduction Dental caries is one…
- Trial name
- Cention-N (NCT07703176)
- Testing
- Cention-N, Resin Composite
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Minia University
Patient Satisfaction
Patient Satisfaction and Oral Healthy Related Quality of Life of Polyetherketoneketone and Metal Framework.
The patients' satisfaction and oral health related quality of life (OHRQL) of different framework material remains uncertain. Thus, the aim of this clinical cross over study was to compare patient satisfaction and OHRQL OF…
- Trial name
- NCT05904756
- Testing
- framework for implant supported prosthesis, fabricated from metal of polyetherketoneketone
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Gingival Recession
Connective Tissue Graft Versus Mucograft Collagen Matrix for Coverage of Multiple Gingival Recession Defects
This study deals with coverage of multiple denuded roots. The current standard treatment requires surgical correction and uses soft tissue taken from the roof of the mouth to enhance results.
- Trial name
- NCT01440426
- Testing
- Autologous connective tissue graft with rotated papilla flap, Collagen matrix construct (Mucograft)
- Where
- 13 sites in Belgium, Germany and 4 more
- Volunteers
- 187 people
- Sponsor
- Maurizio Tonetti
Oral Health Related Quality of Life, Early Childhood Caries
Oral Health-Related Quality of Life of Early Childhood Caries Using Silver Diamine Fluoride Versus Drill and Fill Technique
The clinical trial aims to compare children's oral health-related quality of life (OHrQL) following caries arrest technique using SDF versus conventional drill and fill in the children with ECC
- Trial name
- NCT05337449
- Testing
- silver diamine fluoride, conventional composite resin restoration
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Systemic Scleroderma
Efficacy and Safety of Allogenic Cultured Adipose-derived Mesenchymal Stromal Cell Injections on MoUth Fibrosis and Handicap in Patients With Systemic sclEroderma
Orofacial manifestations and microstomia are a frequent complication in systemic sclerosis (SSc) with a major impact on oral hygiene, dental care and quality of life.
- Trial name
- A-MUSE (NCT07326033)
- Testing
- AdMSC
- Where
- 5 sites in France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Toulouse
Quality of Life
Quality of Life After Denture Relining
Purpose: the aim of the present study was to analyze the impact of mandibular denture relining with soft or hard denture liners in the oral health related quality of life (OHRQoL) of edentulous patients.
- Trial name
- OHRQoL (NCT01928706)
- Testing
- Denture liner Mucopren Soft; Group 1, Denture liner Kooliner; Group 2
- Where
- Brazil
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Fundação de Amparo à Pesquisa do Estado de São Paulo
Oral Health Related Quality of Life
Turkish Validity and Reliability of Oral Health Impact on Daily Life Questionnaire
This study aimed to test Turkish validity and reliability of the Oral Health Impact on Daily Life Questionnaire (OHIDL) in adult endodontic patients.The questionnaire was translated and adapted into Turkish.
- Trial name
- NCT06117189
- Testing
- Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Gingival Hyperpigmentation, Oral Health-Related Quality of Life
MEBO Bio-Dressing on Patient-Reported Outcomes and Tissue Healing Following Rotary Gingival Depigmentation
The purpose of this randomized, single-blind, parallel-group clinical trial is to evaluate the clinical efficacy of Moist Exposed Burn Ointment (MEBO) as a biological topical dressing compared to open secondary healing (no…
- Conditions
- Gingival Hyperpigmentation, Oral Health-Related Quality of Life, Wound Healing
- Trial name
- NCT07876921
- Testing
- MEBO Ointment
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Cairo University
Stabilization of a Full Lower Denture, Edentulism in Lower Jaw
Clinical Evaluation of the Mandibular Mini-Implant Overdenture
Stabilization of existing full lower dentures by means of mini-dental implants (MDI). To test whether 4 mini-implants placed at the front of the lower jaw can stabilize an immediately-modified existing lower denture.
- Conditions
- Stabilization of a Full Lower Denture, Edentulism in Lower Jaw, Lower Denture Made Within Last Few Years
- Trial name
- NCT01064843
- Testing
- Imtec MDI
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Solventum US LLC
Complete Denture, Complete Edentulism
Oral Health-related Quality of Life and Masticatory Function After Using Denture Adhesive and Denture Liner
80 complete denture (CD) wearers participated in the quasi-experimental study. Two outcomes were: 1) oral health-related quality of life (OHRQoL) assessed using the Oral Impacts on Daily Performances index, and 2) masticatory…
- Trial name
- NCT04942262
- Testing
- denture adhesive (Polident®, GlaxoSmithKline, Ireland)
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Edentulous Mouth, Edentulous Jaw
Single-implant Overdentures Retained by the Novaloc Attachment System
The objective of this explanatory mixed methods study is to compare a novel attachment system (Novaloc) to a traditional alternative (Locator) for single implants in the mandible of edentate elders.
- Trial name
- NCT03126942
- Testing
- Novaloc, Locator
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- McGill University
Oral Health Training
Assessment of the Impact of Oral Health Training for Caregivers on the Oral Health-related Quality of Life of Residents in Nursing Homes
With the ageing of the French population, the number of elderly people loosing their autonomy is increasing, leading to a growing need for care in residential establishments for dependent elderly people .
- Trial name
- EHPADENT (NCT07399925)
- Testing
- Caregivers training in oral health in nursing homes
- Where
- France
- Volunteers
- 99 people
- Sponsor
- Nantes University Hospital
Tooyh Discoloration
Impact of At-Home Dental Bleaching on Quality of Life Using OHIP-14
This prospective clinical study aims to evaluate the clinical efficacy of an at-home dental bleaching protocol and its impact on oral health-related quality of life using objective color measurements and patient-reported…
- Trial name
- WID-OHIP (NCT07624344)
- Testing
- Carbamide peroxide 16%
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Advanced or Metastatic Solid Tumor, Relapsed Hematologic Malignancy
Impact of the Coordinated Intervention of the Healthcare Facilities Pharmacist and the Dispensary Pharmacist on the Care Pathway for Cancer Patients Treated With Oral Therapy
The rise of oral therapies in the management of cancers has considerably changed the patient care path. If the oral route is preferred by patients because it offers a better quality of life, it is not without impact for patients…
- Trial name
- IPPACTTO (NCT04327583)
- Testing
- IPPACTTO
- Where
- 7 sites in France
- Volunteers
- 396 people
- Sponsor
- Institut Cancerologie de l'Ouest