Clinical trials: Oral Mucositis, open to volunteers
Mucositis, Peri Implant Mucositis
Effects of Enamel Matrix Derivative in the Treatment of Peri-implant Mucositis
To evaluate the naturally occurring peri-implant mucositis (PM) treatment by means of non-surgical sub-marginal peri-implant instrumentation (NSPI) with or without use of enamel matrix protein derivative (EMD).
- Trial name
- NCT06725095
- Testing
- Enamel Matrix Proteins Derivative
- Where
- Italy
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Catania
Peri Implantitis, Peri Implant Mucositis
Evaluation of 25(OH)D3 and LL-37 Levels in Periimplant Sulcus Fluid
Despite technological advances that have significantly improved dental implant osseointegration and survival rates, biological complications such as peri-implantitis and peri-implant mucositis are common around the implant.
- Trial name
- NCT07280754
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Peri-Implant Health, Peri-Implantitis and Peri-implant Mucositis
Monitoring of Implant Diseases: Diagnosis and Monitoring With aMMP-8 Test Technology
68 patients underwent the aMMP-8 chair-side test as well as clinical traditional measurement methods. Those who had one or more implants in their mouth were selected as patients.
- Trial name
- IMP_TRE (NCT06761521)
- Testing
- Peri-Implantitis and Peri-implant mucositis
- Where
- Finland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hanna Lahteenmaki
Denture Stomatitis
Development of a Sanitizing Tablet for Removable Partial Dentures
The goal of this clinical trial is to learn if a new experimental effervescent tablet works to clean removable partial dentures. It will test if the tablet lowers bacteria and fungi on denture surfaces.
- Trial name
- DSRPD (NCT07608211)
- Testing
- Experimental Effervescent Tablet (NAC/Melaleuca), Commercial Cleansing Tablet (NitrAdine), Phosphate-Buffered Saline (PBS)
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Apthous Ulcer
Recurrent Aphthous Stomatitis Management in Children Using Diode Laser 980 Nanometer Versus Hyaluronic Acid Gel (RCT)
Thirty children with recurrent apthous ulcer will be divided into 3 groups of different treatment modalities to assess their effect on pain, ulcer size, healing and postoperative pain
- Trial name
- RCT (NCT07922681)
- Testing
- laser therapy, Hyaluronic acid group, Negative control group
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Peri Implant Mucositis
Effect of Water Flossing on Gingival Inflammation Around Single Implants
This study aims to evaluate the effect of water floss in reversing peri- implant mucositis around dental implants
- Trial name
- NCT07364916
- Testing
- Water flosser, Tooth brush and string floss
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Oral Mucositis (Ulcerative) Due to Radiation
Efficacy of N-acetylcysteine in Preventing Radiotherapy-Induced Oral Mucositis in Head and Neck Cancer Patients.
A prospective, randomized, controlled, parallel clinical trial will be conducted at Clinical Oncology and Nuclear Medicine Center at Mansoura University Hospital to assess the efficacy of N-acetylcysteine in the prevention of…
- Trial name
- NCT06354712
- Testing
- N-Acetyl-Cysteine with Institutional standard care, Institutional standard care
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Peri-Implantitis, Peri-implant Mucositis
Peri-implantitis Implantoplasty Treatment
This double arm, split-mouth, single centre, controlled, randomised clinical study is designed to examine the effect of implantoplasty in treatment of peri-implantitis.
- Trial name
- NCT04052373
- Testing
- Implantoplasty, Open flap debridement alone
- Where
- 2 sites in Norway
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Peri-implant Mucositis, Peri-Implantitis
Experimental Peri-implant Mucositis on Implant Sites That Were Previously Treated With or Without Implantoplasty
This controlled clinical trial will assess clinically, immunologically, and microbiologically the healing of experimental peri-implant mucositis (PIM) lesions in implants treated previously with implantoplasty (IP) compared to…
- Trial name
- NCT06063876
- Testing
- Induction of experimental peri-implant mucositis, Resolution of experimental peri-implant mucositis
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Radiation-Induced Oral Mucositis (RTOM), Head and Neck Cancer
Sancai Fengsui Decoction for RTOM: A Multicenter RCT
How to promote the prognosis and outcome of RTOM, restore oral function, and improve quality of life are key issues for improving the long-term outcomes of head and neck malignant tumor radiotherapy, and are also integral parts…
- Conditions
- Radiation-Induced Oral Mucositis (RTOM), Head and Neck Cancer, Oral Mucositis of RTOG Grade Greater Than 1
- Trial name
- NCT07692997
- Testing
- Sancai Fengsui Decoction
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Oral Mucositis
A Study to Describe the Effect of Photobiomodulation (Low Level Laser Therapy) in Reducing the Severity and Incidence of Oral Mucositis (Oral Ulceration) in Oral Cancer Patients Undergoing Radiation Treatment
The goal of this study is to describe the effect of photobiomodulation (PBM) on the incidence and severity of oral mucositis in post-operative oral cancer patients receiving radiotherapy +/- chemotherapy.
- Trial name
- PBM (NCT07387978)
- Testing
- photobiomodulation
- Where
- Australia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peter MacCallum Cancer Centre, Australia
Recurrent Aphthous Stomatitis, Aphthous Ulcer
Salivary E-cadherin, Calprotectin, and Matrix Metalloproteinase-9 Levels in Recurrent Aphthous Stomatitis
The goal of this observational cross-sectional study is to determine the salivary levels of E-cadherin, Calprotectin, and Matrix Metalloproteinase-9 (MMP-9) in patients with Recurrent Aphthous Stomatitis (RAS) and to compare them…
- Trial name
- NCT07141758
- Testing
- ELISA
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Selin Yeşiltepe
Atherosclerosis, Endothelial Dysfunction
Impact of Non-surgical Periodontal Therapy in the Improvement of Early Endothelial Dysfunction in Subjects With Peri-implantitis and Peri-implant Mucositis
A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment on endothelial dysfunction parameters in subjects with peri-implantitis/peri-implant mucositis…
- Conditions
- Atherosclerosis, Endothelial Dysfunction, Peri-Implantitis, Peri-implant Mucositis
- Trial name
- NCT05906810
- Testing
- Non-surgical periodontal treatment
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Catania
Oral Ulcer, Oral Mucositis
A Study of Phenytoin Mucoadhesive Film for Oral Ulcers in Healthy Volunteers
The goal of this clinical trial is to learn if a new 1% Phenytoin mucoadhesive film is safe and works to treat oral ulcers in healthy adult volunteers and patients with oral ulcers.
- Conditions
- Oral Ulcer, Oral Mucositis, Aphthous Stomatitis
- Trial name
- PHENO-FILM (NCT07890428)
- Testing
- 1% Phenytoin Mucoadhesive Film, Blank Mucoadhesive Film
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Misr University for Science and Technology
Peri-Implantitis and Peri-implant Mucositis
Occurrence of Peri-Implant Complications: A Multifactorial Cross-Sectional Study
Dental implants have become, over recent decades, one of the most effective and predictable therapeutic options for replacing missing teeth.
- Trial name
- NCT07638969
- Testing
- Dental implant
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain
Oral Mucositis Due to Chemotherapy
Propolis for Management of Chemotherapy-Induced Oral Mucositis in Pediatric Patients
The goal of this clinical trial is to evaluate the efficacy of propolis in the prevention of oral mucositis and reducing pain score in children undergoing chemotherapy, and assessing its impact on body mass index, pediatric…
- Trial name
- NCT07073092
- Testing
- propolis, chlorohexidine mouthwash and topical antifungal
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Gout Initiating Urate-loweringUrate-lowering Therapy, Gout Arthritis
HLA-B*58:01-Guided Therapy for Gout: Effectiveness, Safety, and Cost-Effectiveness
Severe cutaneous adverse reactions (SCARs), such as Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) and drug reaction with eosinophilia and systemic symptoms (DRESS), are rare but life-threatening complications that…
- Conditions
- Gout Initiating Urate-loweringUrate-lowering Therapy, Gout Arthritis, Gout and Hyperuricemia
- Trial name
- HLA-SCREEN (NCT07369622)
- Testing
- HLA-B*58:01 Genotyping, Allopurinol Tablet, Febuxostat
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Haiphong University of Medicine and Pharmacy
Dental Implantation, Missing Teeth
The Effect Of Enamel Matrix Derivatives On Gingival Tissue Thickness
Scientists do research to answer important questions which might help change or improve the way we do things in the future. The investigators know that using Enamel Matrix Derivatives results in thicker gum tissues around teeth.
- Conditions
- Dental Implantation, Missing Teeth, Periodontitis, Adult, Mucositis
- Trial name
- NCT07053969
- Testing
- Enamel Matrix Derivative
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Oral Mucosa Discomfort, Pediatric Cancer
Music Therapy for Oral Mucositis Pain in Pediatric Patients
This mixed-methods pilot study will examine the effect of music therapy on oral mucositis pain in pediatric oncology patients. Oral mucositis, characterized by painful ulcerative lesions in the mouth, is a common side effect of…
- Conditions
- Oral Mucosa Discomfort, Pediatric Cancer, Mucositis Oral
- Trial name
- NCT07653360
- Testing
- Semi-Structured Interviews
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Oral Mucositis
Effect of Cold Application and Artificial Saliva in the Prevention of Chemotherapy-Induced Oral Mucositis
the Objectives of this clinical trial is : 1. To determine the effect of Cold Application for preventing of chemotherapy-Induced oral mucositis in cancer patients. 2.
- Trial name
- NCT07297472
- Testing
- cold application, Artificial Saliva
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karbala University