Clinical trials: Oral Mucositis in Patients Undergoing HSCT
Leukemia, Aplastic Anemia
Methadone as an Alternative Treatment for Children Underdoing HSCT
Mucositis is a normal side effect of stem cell transplant which happens as a result of chemotherapy being given prior to a new donor cell infusion (bone marrow transplant).
- Conditions
- Leukemia, Aplastic Anemia, Bone Marrow Failure Syndromes, SCID
- Trial name
- MATCH (NCT06940570)
- Testing
- PCA plus methadone (Experimental), PCA Alone (SOC)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Texas Southwestern Medical Center
Hematopoietic Stem Cell Transplantation, Low-Level Light Therapy
Low Power Laser Therapy As Prevention Of Oral Mucositis And Oropharyngeal Pain In Patients Undergoing Allogenetic HSCT
Objective: To compare the effects of two low-power laser therapy protocols (application of a wavelength in the mouth, red region and another in the neck infrared region X simultaneous dual application of two wavelengths, red and…
- Conditions
- Hematopoietic Stem Cell Transplantation, Low-Level Light Therapy, Stomatitis
- Trial name
- NCT06071637
- Testing
- Double low-power laser therapy simultaneous applicated
- Where
- 2 sites in Brazil
- Volunteers
- 84 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Multiple Myeloma, Plasma Cell Neoplasm
Ice Chips or Saline Mouth Rinse in Reducing or Preventing Mucositis in Patients Receiving Melphalan and Autologous Stem Cell Transplant for Multiple Myeloma
RATIONALE: Chemoprotective agents may protect normal cells from the side effects of chemotherapy. Ice chips or saline mouth rinse may lessen the severity or help prevent symptoms of mucositis or mouth sores in patients receiving…
- Trial name
- NCT00118339
- Testing
- chemoprotection, complementary or alternative medicine procedure, management of therapy complications
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Fred Hutchinson Cancer Center
Oral Mucositis, Hematopoietic Stem Cell Transplantation (HSCT)
Safety and Efficacy of N-Acetylcysteine Mouthwash in Prevention of Mucositis in HSCT Patients
Oral mucositis (OM) is one of the most frequent complications in patients who undergo HSCT. It not only causes severe discomfort but also affects treatment adherence and increases hospital stays.
- Trial name
- NCT07325383
- Testing
- N-Acetylcysteine 600mg/tab
- Where
- Iran
- Volunteers
- 106 people
- Sponsor
- Tehran University of Medical Sciences
Oral Mucositis
Efficacy of High-Level Laser Therapy in Managing Oral Mucositis Among Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation
The goal of this clinical trial is to learn if high-level laser therapy can manage oral mucositis in pediatric patients undergoing hematopoietic bone marrow transplantation.
- Trial name
- NCT07436650
- Testing
- high power laser therapy, Basic oral care
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Ain Shams University
Gastrointestinal Mucositis, Malignant Neoplasm
Palifermin in Preventing Oral Mucositis Caused by Chemotherapy and/or Radiation Therapy in Young Patients Undergoing Stem Cell Transplant
This randomized phase II trial is studying palifermin to see how well it works compared with a placebo in preventing oral mucositis caused by chemotherapy and/or radiation therapy in young patients undergoing stem cell…
- Trial name
- NCT00728585
- Testing
- Palifermin
- Sponsor
- Children's Oncology Group