Clinical trials: Oral Pain
Infant Conditions
Be Sweet to Babies During Nasolaryngoscopy
The investigators want to know if sugar water containing 24% sucrose is helpful in reducing pain in babies during scopes.
- Trial name
- NCT06641687
- Testing
- 24% Sucrose, Sterile water
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- The Hospital for Sick Children
Cramps
Does Oral Magnesium Substitution Relieve Pregnancy Induced Leg Cramps ?
This is a trial of treatment with tablets containing magnesium for leg cramps in pregnancy.
- Trial name
- NCT00525317
- Testing
- "Nycoplus Magnesium" (120 mg x 3 daily for 2 weeks)
- Volunteers
- 45 people
- Sponsor
- Oslo University Hospital
Pain, Stomatognathic Diseases
The Effect of Different Physiotherapeutic Stimuli on Stomatognathic System Structures.
The study will determinate influence of four selected physiotherapeutic procedures on the pain intensity and the range of mandibular mobility in patients with myofascial disorders in the SS.
- Conditions
- Pain, Stomatognathic Diseases, Muscle Hypertonia, Myofacial Pain Syndromes
- Trial name
- NCT05021874
- Testing
- Four different physiotherapy treatment
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin
Pain
Metamizol for the Treatment of Neoplastic Chronic Pain
Study to evaluate the efficacy of metamizole in reducing morphine requirements in patients with moderate to severe chronic cancer pain in comparison to administration of placebo or diclofenac.
- Trial name
- NCT02181920
- Testing
- Metamizole, Diclofenac
- Volunteers
- 6 people
- Sponsor
- Boehringer Ingelheim
Postoperative Pain
Analgesic Potentials of Preoperative Pregabalin,Magnesium Sulphate and Their Combination in Acute Post-thoracotomy Pain
This study evaluates the effect of giving preoperative adjuvant drug as pregabalin or magnesium sulphate or a combination of both drugs to decrease postoperative morphine consumption and pain intensity in the first 24 hours in…
- Trial name
- NCT02678117
- Testing
- Pregabalin & Magnesium sulphate
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- National Cancer Institute, Egypt
Trigeminal Neuralgia
Efficacy of Guanfacine and Lidocaine Combination in Trigeminal Nerve Block for Pain Management in Trigeminal Neuropathy
A phenome-wide association study (PheWAS) identified an association between a loss of function variant in the human alpha 2B adrenergic receptor gene and trigeminal nerve disorders.
- Trial name
- NCT03865940
- Testing
- Lidocaine, Guanfacine
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Vanderbilt University Medical Center
Pain, Inflammation
UVB Model Validation Study
Single centre, subject and observer blinded, placebo controlled, cross-over study of the effect of oral ibuprofen and topical hydrocortisone-21-acetate on ultraviolet radiation (UVR) induced pain and inflammation in healthy…
- Conditions
- Pain, Inflammation, Healthy Volunteers
- Trial name
- NCT01055249
- Testing
- Ibuprofen, Hydrocortisone, Hydrocortisone
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- X-pert Med GmbH
Arthroscopic Knee Repair, Arthroscopic Hip Repair
PO Methadone Ortho Outpatient
The goal of this clinical trial is to learn if oral methadone given before surgery works to minimize post-operative pain and opioid usage.
- Trial name
- NCT06351215
- Testing
- Methadone group
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Keck School of Medicine of USC
Apical Periodontitis
Apical Patency, Periapical Lesion Volume, and Postoperative Pain After Root Canal Treatment
This prospective clinical study evaluated whether maintaining apical patency during single-visit root canal treatment influences postoperative pain in adults with single-rooted maxillary anterior teeth and chronic apical…
- Trial name
- NCT07782515
- Testing
- Apical Patency During Root Canal Treatment, Root Canal Treatment Without Apical Patency
- Where
- Turkey (Türkiye)
- Volunteers
- 113 people
- Sponsor
- Recep Tayyip Erdogan University
Pain, Intractable
Phase II Clinical Trial of Fentanyl Transdermal Matrix Patch, in the Management of Cancer Pain- Assessment of Effectiveness, Safety and Pharmacokinetics -
The purpose of this study is to verify the effectiveness, safety and pharmacokinetics of fentanyl transdermal matrix patches containing either 12.5 mcg/hr, 25 mcg/hr, or 50 mcg/hr in Japanese patients with cancer pain who have…
- Trial name
- NCT00216658
- Testing
- fentanyl
- Volunteers
- 87 people
- Sponsor
- Janssen Pharmaceutical K.K.
Neuralgia, Postherpetic
Safety and Preliminary Efficacy of MK0759 in Postherpetic Neuralgia (PHN)(0759-004)
The purpose of this study is to test the safety and effect of MK0759 in relieving neuropathic pain as experienced by patients with postherpetic neuralgia (PHN).
- Trial name
- NCT00245544
- Testing
- MK0759
- Volunteers
- 20 people
- Sponsor
- Merck Sharp & Dohme LLC
Gingival Recession, Palate; Wound
To Measure Pain Perception Following De-Epithelized Free Gingival Graft Harvesting
This randomized clinical comparative study will evaluate the postoperative pain following the FGG graft harvest procedure technique covered by four different methods for coverage of the palatal donor site.
- Trial name
- NCT03895476
- Testing
- palatal wound will be cover with collagen and sutures, palatal wound covered with platelet rich fibrin, palatal wound covered with a collagen sponge and cyanoacrylate
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Oral Mucositis, Pain
Cryotherapy for Prevention of Oral Mucositis in Children Undergoing Hematopoietic Stem Cell Transplantation
Oral mucositis (OM) is a common adverse effect of chemotherapy, radiotherapy and conditioning regimens before Hematopoietic Stem Cell Transplantation (HSCT).
- Conditions
- Oral Mucositis, Pain, Infection, Nutrition Aspect of Cancer
- Trial name
- NCT01789658
- Testing
- Cryotherapy
- Where
- 5 sites in Sweden
- Volunteers
- 53 people
- Sponsor
- Uppsala University
Apical Periodontitis, Postoperative Pain
Effectiveness of Different Obturation Techniques
Aim: Evaluation of the effect of different obturation techniques on postoperative pain level and radiographic healing on non-surgical endodontic retreatment (NSER) applied in a single visit in teeth with single root canal and…
- Conditions
- Apical Periodontitis, Postoperative Pain, Endodontically Treated Teeth
- Trial name
- NCT06226740
- Testing
- Single Visit Non Surgical Root Canal Treatment Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Pulpitis
Oral Glucocorticoids Effect on Post Endodontic Pain
The aim of this single-center randomized, double-blind, placebo-controlled clinical trial is to assess the effect of preoperative, single, oral dose of prednisolone on postoperative pain and medication intake in patients with…
- Trial name
- NCT02819648
- Testing
- Prednisolone, Control
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post-operative Pain
Postoperative Pain and Morphine Consumption After Mastectomy - Lyrica
This study will compare the effects of oral pregabalin with placebo on postoperative pain and morphine usage after mastectomy. Pregabalin is an anticonvulsant agent approved by the United States Food and Drug Administration (FDA)…
- Trial name
- NCT01391858
- Testing
- lyrica
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Texas Southwestern Medical Center
Oral Contraceptive, Headache
Effect of a New Oral Contraceptive Pill on Hormone Related Symptoms Such as Pelvic Pain and Headache
The aim of the present study is to investigate whether women taking a new combined oral contraceptive pill (SH T00658ID, estradiol valerate/dienogest) experience fewer hormone withdrawal-associated symptoms such as pelvic pain or…
- Conditions
- Oral Contraceptive, Headache, Pelvic Pain
- Trial name
- NCT00778609
- Testing
- EV/DNG (Qlaira, BAY86-5027)
- Where
- 63 sites in Australia, Finland and 7 more
- Volunteers
- 449 people
- Sponsor
- Bayer
Facial Pain
Celebrex for Pain Relief After Oral Surgery
This study will evaluate the effects of the new anti-inflammatory drug, Celebrex, on relieving pain after oral surgery. It is also designed to assess the drug's selective inhibition of a chemical called cyclooxygenase-2 and not…
- Trial name
- NCT00006299
- Testing
- Celebrex
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Endometrioma
Desogestrel for the Preoperative Treatment of Endometrioma Compared With Placebo
Use of the oral desogestrel compared with placebo for preoperative treatment of endometrioma in the patient who underwent to surgery in next 3 months The result will be evaluated on cyst diameter, the associated pain and side…
- Trial name
- NCT04941833
- Testing
- Desogestrel Oral Tablet
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Impacted Tooth, Postoperative Complications in Maxillofacial Surgery
Effectiveness of Postoperative Topical and Oral Antibiotics on Impacted Mandibular 3rd Molar Surgery.
This randomized controlled trial evaluates the effectiveness of postoperative topical antibiotics compared with oral antibiotics in patients undergoing surgical extraction of impacted mandibular third molars.
- Conditions
- Impacted Tooth, Postoperative Complications in Maxillofacial Surgery, Surgical Wound Infection, Facial Pain
- Trial name
- POTA-M3S (NCT07573033)
- Testing
- Topical Antibiotic, Oral antibiotic therapy
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Liaquat College of Medicine and Dentistry