Clinical trials: Oral Processing
Dysphagia
Chewing and Oral Processing of Solid Food
Food texture modification is commonly used as an intervention for people with dysphagia (swallowing impairment). However, the field currently lacks a proper understanding of how this intervention works.
- Trial name
- NIH_HVX6 (NCT05594173)
- Testing
- Food texture modification
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Type 2 Diabetes, Inflammation
Effect of Alcohol on Cephalic Phase Reflex and Gene Expression
Moderate alcohol consumption has consistently been associated with lowered risk of developing type two diabetes mellitus compared to abstainers and heavy drinkers.
- Conditions
- Type 2 Diabetes, Inflammation, Carbohydrate&Lipid Metabolism, Oral Processing
- Trial name
- AR22 (NCT00652405)
- Testing
- alcohol
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- TNO
Menstrual Cycle, Hormonal Contraception
Oxytocin and Reward Processing in Women
Oxytocin is a hypothalamic neuropeptide that is best known for its peripheral physiological effects in the female organism i.e., uterine contractions during birth.
- Trial name
- NCT06222749
- Testing
- Intranasal oxytocin administration
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- International Research Training Group 2804
Autism
Sensory Adapted Dental Environments to Enhance Oral Care for Children
The goal of this project is to examine the efficacy of a sensory adapted dental environment (SADE) for children who have difficulty tolerating oral care in the dental clinic.
- Trial name
- SADE-2 (NCT02430051)
- Testing
- Sensory Adapted Dental Environment
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Oral Hormonal Contraceptive Use, Neural Activity
Contraceptive Hormone and Reward Measurement (CHARM Study)
Purpose of this study: The purpose of this study is to learn more about how hormonal oral contraceptives affect brain processes and emotional wellbeing.
- Conditions
- Oral Hormonal Contraceptive Use, Neural Activity, Mood, Hedonic Function
- Trial name
- CHARM (NCT05058872)
- Testing
- Levonorgestrel/ethinyl estradiol
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Postprandial Glycemic Responses
Glycemic Response to an Innovative Cookie to Promote Human Health
The aim of this study is to investigate whether using a coarse wheat fraction in wire-cut cookie making induces a lower glycemic response in healthy subjects compared to wheat flour.
- Trial name
- GRINCH (NCT06005415)
- Testing
- Wire-cut cookie
- Where
- Belgium
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Subjective Appetite and Satiety
Chewy Satiety - the Interplay Between Food Structure, Oral Processing and Satiety
This study examines if there are differences in satiety responses between structurally different wholegrain rye products.
- Trial name
- NCT02554162
- Testing
- Rye products with varying structures
- Where
- Finland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- VTT Technical Research Centre of Finland
Glucose Response, Glycemic Index
Glycemic and Insulinemic Response of Durum Wheat Bread
In the last decades, the consumption of energy-dense diets, primarily consisting of highly digestible starchy foods like bread, along with a global increase in obesity rates and a sedentary lifestyle, has emerged as the main…
- Conditions
- Glucose Response, Glycemic Index, Insulin Response, Oral Processing
- Trial name
- NCT06152874
- Testing
- consumption of glucose solution 1, consumption of glucose solution 2, consumption of Bread A and oral processing
- Where
- Italy
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Udine
Feeding Practices, Food Acceptance
Textured Food Introduction Information and Parental Feeding Practices
The purpose of this study is to conduct an intervention with 60 parents of 8 months old children to test the effect of recommendations, compared to usual care, promoting the introduction of textured foods between 8 and 15 months…
- Trial name
- PATATE (NCT04570059)
- Testing
- Counselling on textured food introduction between 8 and 15 months
- Where
- France
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Skin Ageing, Healthy Ageing
Effects of a Multi-Targeted Oral Supplement on Skin, Hair, Sleep, Energy, Cognition, Libido and Epigenetic Biological Clock Age
This study evaluated the effects of a daily oral supplement regimen (Advanced ID Brain, Heart and Eye Omega Gel Capsules taken with Advanced ID Longevity and Collagen Complex Powder) on measures of skin condition, hair, sleep…
- Conditions
- Skin Ageing, Healthy Ageing, Effect of Oral Nutritional Supplementation on Skin, Hair, Sleep, Energy, Cognition and Sexual Wellbeing in Healthy Adults, Longevity
- Trial name
- IDF-AID-1 (NCT07827651)
- Testing
- Advanced ID
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- IDI Skincare Limited
Deafness; Perception, Bilateral
Plasticity and Cross-modal Interactions in Profoundly Deaf Adults
The aim of this study is to evaluate cerebral asymmetry for face processing in a group of profoundly deaf participants and a group of hearing controls by the mean of fMRI measure.
- Trial name
- PLASMODY (NCT02632214)
- Testing
- fMRI measure
- Where
- France
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Healthy
Effect of Oral Oxytocin on Women's Response to Emotional Stimuli
The main aim of the study is to investigate whether orally administered oxytocin (24IU) could modulate females' neural and behavioral responses to affective stimuli including emotional faces and affective scenes.
- Trial name
- NCT05073939
- Testing
- Oral Oxytocin
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Healthy
Oral Oxytocin Modulation of Responses to Emotional Stimuli
The main aim of the study is to investigate whether orally administered oxytocin (24IU) can modulate neural and behavioral responses to positive and negative valence stimuli during basal (emotional scenes) and higher order…
- Trial name
- NCT04320706
- Testing
- Oral Oxytocin
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Vomiting
Observational Study Evaluating The Processing Or Breakdown Of GW679769 In Subjects With Hepatic Impairment
The purpose of the study is to evaluate how subjects with mild or moderate liver problems process or breakdown the study drug GW679769 in their bodies as compared to healthy subjects.
- Trial name
- NCT00359177
- Testing
- GW679769
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Oral Processing Behavior, Mastication
Oral Processing Behavior of Gluten-free and Gluten-containing Breads
To attend the increasing demand for gluten-free products, new gluten-free formulations emerged in the market containing alternative ingredients to mimic the protein functionality of wheat.
- Conditions
- Oral Processing Behavior, Mastication, Swallowing
- Trial name
- NCT04671277
- Testing
- Chewing of breads
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Udine
Food Oral Processing, Texture Preference
Evolution of Food Oral Processing Behaviours, Food Bolus Formation and Texture Preferences Between 6 to 12 Years Old and Adult Age
This cross sectional study investigates how the oral physiological changes during the period of dental transition (6-12 years old) influence on texture preferences, food oral processing behaviour and food bolus properties, for…
- Trial name
- MARELLE (NCT07631195)
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Eating Behavior
Al Dente or Well Done? The Eating Rate of a Pasta Meal Modified by Texture
Rationale: The world-wide rising obesity rates are a major health problem. Therefore, people should moderate food intake. A lower eating rate will decrease the energy intake.
- Trial name
- ESPA (NCT05019872)
- Testing
- (Components of) pasta meal
- Where
- Netherlands
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Autism
Sensory Adapted Dental Environment to Enhance Oral Care for Children With ASD
The goal of this project is to collect information that will support a later clinical trial on the effectiveness of a specially adapted dental environment for children who have difficulty tolerating oral care in the dental…
- Trial name
- SADE (NCT02077985)
- Testing
- Sensory Adapted Dental Environment
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Healthy
The Effects of Intranasal and Oral Administration of Oxytocin on Responses to Emotional Scenes
The study will investigate whether oxytocin administered either intranasally or orally (lingual) (24 international units, IU) can differentially modulate men's neural and behavioral responses to emotional scenes using an implicit…
- Trial name
- NCT05532501
- Testing
- Oral Oxytocin, Intranasal Oxytocin
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Older Adults, Appetitive Behaviour
Oral Processing and Appetite in Older Adults
The goal of this observational study is to learn about changes in oral processing and appetite in older adults aged 65+ years old.
- Conditions
- Older Adults, Appetitive Behaviour, Food Intake, Oral Processing
- Trial name
- NCT05671003
- Where
- United Kingdom
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Reading