Clinical trials: Organ Transplants
Post Traumatic Stress Disorder, Family
Psychological Impact in a Relative, Following the Announcement of the Death of a Loved One After Cardiac Arrest and the Early Request for Organ Donation
The fight against the scarcity of grafts is a major public health issue in France. Despite a very good success rate of transplants from brain-dead donors or living donors, the waiting time for transplantation continues to…
- Conditions
- Post Traumatic Stress Disorder, Family, Psychological Distress, Organ and Tissue Procurement
- Trial name
- REPERPSY (NCT03721770)
- Where
- France
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- frederic ADNET
Organ or Tissue Transplant; Complications, Reiki
The Effect of Remote Reiki Treatment on Hopelessness, Fatigue and Pain in Patients Awaiting Organ Transplantation
The treatment and care of chronic kidney failure is a long-term process, and patients are significantly affected by this condition.
- Trial name
- NCT07394660
- Testing
- remote reiki
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bozok University
Organ Transplantation
Antibody Levels Against 2009 Influenza A H1N1 One Year After Vaccination With Pandemrix and 2010 Fluarix Booster in Organ Transplant Recipients.
Organ transplant patients who participated in a retrospective study and received 2009 Pandemrix vaccine during autumn 2009 are included in this study.
- Trial name
- NCT01256931
- Where
- Sweden
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Sahlgrenska University Hospital
Transplants
Creating a Patient-centered Report Card for Solid Organ Transplant Candidates
Choosing a transplant center that will accept a particular candidate can be difficult and challenging for patients with end-stage organ failure.
- Trial name
- NCT03610555
- Testing
- Intervention 1 - SRTR (age question 1st), Intervention 2 - SRTR (BMI question 1st), Intervention 3 - TCST (age question 1st)
- Where
- United States
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Ajay Israni, MD
Complications of Organ Transplant Stem Cells Umbilical Cord
Treatment Protocol of Child SAA With the Injection of Mesenchymal Stem Cells（Umbilical Cord Derived）
Mesenchymal Stem Cells (MSC) is a non Hematopoietic Stem Cells (HSC) in adult bone marrow and takes part in the bone marrow microenvironment.
- Trial name
- MSC-SAA (NCT02218437)
- Testing
- MSC+ATG
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences
Organ Donation
Survey of Our Future Healthcare Professionals on Their Training, Knowledge, and Experience Regarding Organ Donation
In 2024, 29,000 people were waiting for an organ transplant in France, and only 6,034 transplants were performed during the year. 852 people died in 2024 while waiting for a transplant.
- Trial name
- Info-PMO (NCT07351188)
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Kidney Transplantation, Liver Transplantation
Cytokine Kinetics Test to Assess the Presence or Absence of Tolerance in Organ Transplant
The purpose of this pilot study is to determine if there is clinical correlation between the CKT and transplant recipients who are known to be on minimal or no immunosuppression (presumed tolerant) and those who are on…
- Trial name
- NCT00585858
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Organ Transplants
RCT Comparing Tailored Versus Targeted Organ Donation Video Education
The primary purpose of this 3-phase mixed methods design study is to investigate how presenting content at varying levels of audience specificity (generic, targeted, and tailored) influences organ donor registration behavior…
- Trial name
- NCT02676102
- Testing
- Control Group, Targeted Intervention, Tailored Intervention
- Where
- United States
- Volunteers
- 1,440 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Organ Transplant Rejection, Psoriasis
Safety and Pharmacokinetics of Sustained-release Depot Tacrolimus: A First-in-human Study
This first-in-human study is designed to assess the safety and pharmacokinetic (PK) profile of sustained-release (SR) depot tacrolimus, which will be administered as a single dose of 0.1 mg/kg by subcutaneous (SC) injection in…
- Trial name
- NCT03626714
- Testing
- Sustained Release Injectable Tacrolimus
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Auritec Pharmaceuticals
SARS-CoV-2 Infection, Active Immunization
Saxon SARS-CoV-2 Infection and Vaccination Study in Dialysis Patients, Solid Organ Recipients and Staff
To investigate short- (3 and 8 weeks) and long-term (6, 9, 12, and 18 months) immune protection or response at the humoral and cellular levels before and after SARS-CoV-2 infection or vaccination in patients with moderately…
- Conditions
- SARS-CoV-2 Infection, Active Immunization, Immune Response, Immunosuppression
- Trial name
- DIA-Vacc (NCT04799808)
- Where
- Germany
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
SARS-CoV-2
A Study to Evaluate Safety and Immunogenicity of mRNA-1273 Vaccine to Prevent COVID-19 in Adult Organ Transplant Recipients and in Healthy Adult Participants
This is an open-label study to evaluate the safety, reactogenicity, and immunogenicity of mRNA-1273 Severe Acute Respiratory Syndrome coronavirus (SARS-CoV-2) vaccine in adults with a kidney or liver solid organ transplant (SOT)…
- Trial name
- NCT04860297
- Testing
- mRNA-1273
- Where
- 15 sites in United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
Organ Finding
The Knowledge Levels and Attitudes of the People Living in Nevşehir on Organ Donation and Transplantation
In this descriptive study, the purpose was to determine the knowledge levels and attitudes of the people in Nevsehir, Turkey on organ donation.
- Trial name
- NCT02931318
- Testing
- Nevsehir
- Volunteers
- 414 people, healthy volunteers welcome
- Sponsor
- Nevsehir Public Hospital
COVID-19, Organ Transplant
Immune Registry for Organ Transplantation From COVID Positive Donors.
The purpose of this study is to collect data generated by standard clinical practice to determine the short term and long term clinical outcomes of recipients of solid organ transplantation from COVID-19 infected donors and…
- Trial name
- NCT05595837
- Testing
- Standard organ transplant
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Solid Organ Transplantation, Chronic Kidney Disease
Immune Response to Influenza Vaccination
The purpose of this study is to evaluate the immune response to a routine influenza vaccination. Influenza vaccination is given as part of routine standard of care in these individuals and is not part of the study protocol.
- Trial name
- NCT00551837
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Tissue and Organ Procurement, Health Behavior
Community Trial to Enhance Organ Donation
The purpose of this study is to determine the effect of a 5-minute video intervention regarding organ donation and transplantation on increasing the number of organ donor cards signed in Northeastern Ohio Bureau of Motor Vehicles…
- Trial name
- NCT00870506
- Testing
- video
- Where
- United States
- Volunteers
- 973 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Immunotherapy, Cutaneous Squamous Cell Carcinoma
Immunotherapy After Transplantation for Skin Cancer Prevention in Organ Transplant Recipients
This clinical trial aims to investigate the efficacy of Calcipotriol ointment combined with 5-FU cream in Organ Transplant Recipients (OTRs) to determine if it can stimulate the immune cells against actinic keratoses precancerous…
- Conditions
- Immunotherapy, Cutaneous Squamous Cell Carcinoma, Actinic Keratoses, Organ Transplant Recipients
- Trial name
- NCT04642287
- Testing
- Calcipotriol Only Product in Cutaneous Dose Form, Vaseline, Topical 5FU
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Organ Transplantation
Antibody Production Following H1N1 Influenza Vaccination in Organ Transplant Patients
Organ transplant patients and staff members at the Transplant Institute have received pandemic H1N1 influenza vaccine (Pandemrix) and specific antibody production was measured by haemagglutination inhibition according to the…
- Trial name
- NCT01254955
- Testing
- H1N1 vaccine Pandemrix
- Where
- Sweden
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sahlgrenska University Hospital
Quality of Life
Transplantoux Health Evaluation Study
The primary aim is to evaluate the short- and long-term effect of the 'Transplantoux' exercise training intervention in solid organ transplant recipients with matched control sample of transplant recipients in view of selected…
- Trial name
- THES (NCT02533245)
- Testing
- Home-based indiviualized exercise training program, Supervised group training sessions, Climb of the Mont Ventoux
- Where
- Belgium
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Organ Donation
RCT- Comparing Testimonial Versus Documentary Organ Donation Video Education
Investigators will evaluate organ donation educational videos with a 2x3 single blinded Randomized Control Trial (RCT) in partnership with our 26 Latino Owned Barbershops (LOBs).
- Trial name
- NCT02836301
- Testing
- Control ending - Uplifting, Negative Consequences Ending, Unresolved Ending
- Where
- United States
- Volunteers
- 1,440 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health