Clinical trials: Orientation
Knee Osteoarthritis
Effect of Physiotherapy After Total Knee Replacement
Physiotherapy plays an important part in rehabilitation after total knee arthroplasty. Even if this is a common practice, few studies have been performed on this issue.
- Trial name
- NCT00807716
- Testing
- walking skill group, usual physiotherapy care
- Where
- Norway
- Volunteers
- 57 people
- Sponsor
- University of Oslo
Anxiety Disorders, Depressive Disorder
Islamic-Oriented vs. Standard Ericksonian Hypnotherapy for Anxiety and Depression
This randomized controlled trial (RCT) aims to compare the effectiveness of Islamic-Oriented Ericksonian Hypnotherapy (IEH) and Standard Ericksonian Hypnotherapy (SEH) in reducing symptoms of anxiety and depression.
- Trial name
- IEH-RTC (NCT06844058)
- Testing
- Islamic-Oriented Ericksonian Hypnotherapy (IEH), Standard Ericksonian Hypnotherapy (SEH)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul Nisantasi University
Ewing Sarcoma, Risk Stratification
Risk Stratification Oriented Treatment of Pediatric Ewing Sarcoma: a Prospective Multicenter Cohort Study
The aim is to evaluate the outcome and safety of risk-stratification oriented treatment for pediatric Ewing sarcoma in multicenters .
- Trial name
- NCT06451302
- Testing
- cyclophosphamide, adriamycin, vincristine，Ifosfamide，etoposide
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Yizhuo Zhang
Reactive Hyperemia, Micro RNA
Effect on Markers of Cardiovascular, Reproductive and Cancer Risk From Firefighting Training
Epidemiological studies based on Danish registries have observed that Danish male firefighters have more cardiovascular disease, infertility diagnose and a trend to increased risk of cancer than other Danish employed males.
- Conditions
- Reactive Hyperemia, Micro RNA, Heart Rate Variability, DNA Strand Breaks
- Trial name
- BIOBRAND3 (NCT05753254)
- Testing
- Firefighting training exercises with no fire, Firefighting training exercises under wood fire, Firefighting training exercises under gas fire
- Where
- 2 sites in Denmark
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- National Research Centre for the Working Environment, Denmark
Coronary Artery Disease, Hypercholesterolemia
The Role of Atorvastatin on Monocyte Function in Patients With Coronary Artery Disease and Hypercholesterolemia
The aim of this study is to determine, whether an intensified atorvastatin therapy can improve monocyte function in patients with coronary artery disease and hypercholesterolemia.
- Conditions
- Coronary Artery Disease, Hypercholesterolemia, Monocyte Function
- Trial name
- NCT00329069
- Testing
- atorvastatin (drug)
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Voice Disorders, Gastroesophageal Reflux
Quantifying Effects of Treatment of Pediatric Dysphonia
The diagnosis and management of childhood dysphonia is a significant clinical problem; however, there have been few studies aimed at defining standard assessment methods for pediatric dysphonia.
- Trial name
- NCT00237679
- Testing
- Neuromuscular Electrical Stimulation, Unstimulated
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Wisconsin, Madison
Metacognitive Capacities
Psychological Factors In The Treatment Of Bipolar Mood Disorders
The aim of this study is to trial an intervention targeting potential deficits in an individual's ability to form, and reflect upon, ideas about themselves and others (known as metacognitive capacities), specifically in relation…
- Trial name
- NCT03266679
- Testing
- Metacognitive Reflection and Insight Therapy - Adapted
- Where
- 2 sites in Australia
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Queensland University of Technology
Diabetic Peripheral Neuropathy
Feldenkrais vs. Task Oriented Gait Training on Diabetic Peripheral Neuropathy
Diabetic Peripheral Neuropathy (DPN) causes balance problems, falls, and sensory loss in the feet. This study compares two non-drug exercise programs to see which works better.
- Trial name
- FEToG-DPN (NCT07616661)
- Testing
- Feldenkrais Exercises, Task Oriented Gait Training, baseline warm up and cool down Exercises
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- University of Faisalabad
Obesity
Cognitive Behavioural Therapy for Obesity
The purpose of this study is to evaluate the effectiveness of a cognitive behavioural treatment (CBT) designed to help obese patients lose weight and to maintain their weight losses over time.
- Trial name
- NCT00294268
- Testing
- cognitive behavioural therapy
- Where
- Australia
- Volunteers
- 24 people
- Sponsor
- University of Sydney
Childhood Cancer
Neutrophil Extracellular Traps Formation Post-hematopoietic Stem Cell Transplantation
Identifying the post-transplantation phase wherein neutrophils recover their ability to release NETs could shed new light on the mechanism responsible for the increased susceptibility to infection among these patients and aid in…
- Trial name
- NETs post HSCT (NCT01491230)
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Coronary Artery Disease With Myocardial Infarction
Pragmatic Trial Comparing Symptom-Oriented Versus Routine Stress Testing in High-Risk Patients Undergoing Percutaneous Coronary Intervention
The primary objective of the POST-PCI trial is to compare the clinical outcomes of a post-percutaneous coronary intervention(PCI) aggressive management strategy of routine noninvasive functional testing to a usual-care strategy…
- Trial name
- POST PCI (NCT03217877)
- Testing
- routine stress testing, No Routine stress testing
- Where
- 11 sites in South Korea
- Volunteers
- 1,700 people
- Sponsor
- Seung-Jung Park
Anterior Cruciate Ligament Injuries, Meniscus Tear
Magic Angle Direction Imaging (MADI) ACL Study
This study will be conducted to see if a new Magnetic Resonance Imaging (MRI) scanner could give additional information or help view the body in a different way.
- Trial name
- MADI (NCT07366619)
- Testing
- Magnetic Resonance Imaging
- Where
- 2 sites in United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Clinical High Risk for Psychosis (CHR), Suicidal Ideation
Developing a Recovery-Oriented Suicide Prevention Program for Young People at Clinical High Risk for Psychosis
Young people at clinical high risk for psychosis are more likely to experience suicide thoughts than the general population, but there are few suicide prevention programs designed specifically for them.
- Conditions
- Clinical High Risk for Psychosis (CHR), Suicidal Ideation, Psychosis, Suicidal Behavior
- Trial name
- NCT07756567
- Testing
- Suicide Prevention Intervention, Standard Care (in control arm)
- Where
- 2 sites in United States
- Volunteers
- 108 people
- Sponsor
- University of California, San Diego
Pancreatic Cancer, Chemotherapy Effect
Pembrolizumab Plus Chemotherapy in 1st Line Treatment of Pancreatic Cancer
This is an open-label, phase 2 study of Pembrolizumab in combination with chemotherapy in chemotherapy-naïve advanced pancreatic cancer
- Trial name
- NCT04447092
- Testing
- Gemcitabine, Nab-paclitaxel, Pembrolizumab
- Where
- South Korea
- Volunteers
- 77 people
- Sponsor
- Seoul National University Hospital
Quality of Hospital Entrance Reception, Social Robots
Hospitality Oriented Service Perception Evolution With Robots (HOSPER)
The HOSPER project aims to determine if using Pepper and NAO social robots at the IRCCS INRCA in Ancona's (Italy) entrance is a viable way to improve the current reception and guidance services for hospital visitors.
- Trial name
- HOSPER (NCT07002411)
- Testing
- Innovative hospital reception service with social robot NAO, Innovative hospital reception service with social robot PEPPER
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani
Opiate Use Disorder
Mindfulness-Oriented Recovery Enhancement (MORE) in Heroin Addiction
In this study, neuroimaging of reward processing, drug cue reactivity and inhibitory control is used before and immediately after 8 weeks of two types of group therapy in individuals with opioid addiction; clinical outcomes will…
- Trial name
- MORE (NCT04112186)
- Testing
- Behavioral group therapy #1, Behavioral group therapy #2
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cardiovascular Diseases
Effects of a Legume-rich Diet in the Context of the Planetary Health Diet Compared to a Western-oriented Dietary Pattern in Participants with Increased Cardiometabolic Risk
The aim of the study is to systematically investigate the effects of a diet enriched with legumes in a dietary pattern approach (Planetary Health Diet) compared to a control diet low in legumes in older people with a risk…
- Trial name
- LeguPlan_2 (NCT06700954)
- Testing
- legume-rich Planetary Health Diet, control diet based on Western Diet low in legumes
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Bonn
Obsessive Compulsive Disorder
Combined Cortical/Subcortical Recording and Stimulation as a Circuit-Oriented Treatment for Obsessive-Compulsive Disorder
This study involves the use of the Medtronic PC+S deep brain stimulation for the treatment of intractable OCD.
- Trial name
- NCT03184454
- Testing
- Medtronic Percept Deep Brain Stimulation
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- Massachusetts General Hospital
Multiple Sclerosis
Unravelling The Optimisation And Consolidation Of Motor Skills In People With Multiple Sclerosis With Mild to Moderate Gait Impairment: A Feasibility Study
The goal of this feasibility study is to test the safety and effectiveness of an high-intensity task oriented circuit training program, followed by three months of telerehabilitation in people with mild to moderate Multiple…
- Trial name
- UNLOCK MS MGI (NCT07058870)
- Testing
- High Intensity Task Oriented Circuit Training + Telerehabilitation
- Where
- Italy
- Volunteers
- 18 people
- Sponsor
- University Hospital of Ferrara
Sudden Infant Death Syndrome (SIDS)
Comparing Children's Book to Brochures for Safe Sleep Education in a Home Visiting Program
This randomized controlled trial compares a specially-designed children's book to standard brochures for safe sleep education and reduction of Sudden Infant Death Syndrome (SIDS) risk in a high-risk population of young…
- Trial name
- NCT02376673
- Testing
- Children's Book, Standard Brochures
- Where
- United States
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati