Clinical trials: Orofacial Pain
Temporomandibular Disorder, Myofascial Pain
CBD (Cannabidiol) Intraoral Application and TMD (Temporomandibular Disorders)
The aim of the project is to assess the effectiveness of reducing the masseter muscles tension and hyperactivity in patients with a painful form of TMD by using polymers containing CBD compared to placebo polymers.
- Conditions
- Temporomandibular Disorder, Myofascial Pain, Orofacial Pain, CBD
- Trial name
- NCT05562635
- Testing
- 5% polymer gel with CBD application, 10% polymer gel with CBD application
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Facial Neuralgia, Pain
Studies of Dextromethorphan and Topiramate to Treat Oral and Facial Pain
This study will evaluate the safety and effectiveness of two drugs-dextromethorphan and topiramate-in treating orofacial (mouth and face) pain.
- Conditions
- Facial Neuralgia, Pain, Trigeminal Neuralgia
- Trial name
- NCT00001725
- Testing
- Dextromethorphan
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Temporomandibular Disorders (TMD)
Multimodal Physiotherapy Versus Occlusal Splint in Adults With Temporomandibular Disorders
The aim of this study is to compare the effects of two therapeutic approaches commonly used in the management of muscular temporomandibular disorders (TMD): a multimodal physiotherapy program combining manual therapy and…
- Trial name
- NCT07410091
- Testing
- Multimodal Physiotherapy, Occlusal Splint
- Where
- 3 sites in Portugal
- Volunteers
- 24 people
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Orofacial Pain
A Comparative Evaluation of Diclofenac Sodium Transdermal Patch, Oral Diclofenac Sodium With Intramuscular Injections of Diclofenac Sodium in Patients Suffering From Oral Pain
Newer drug delivery systems such as transdermal patches using pain relieving or modifying agents emerged as mainstream treatment protocol for management of pain on the outpatient basis.
- Trial name
- NCT03221946
- Testing
- Diclofenac Sodium, Diclofenac
- Where
- India
- Volunteers
- 90 people
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
Trigeminal Neuralgia (TN), Orofacial Pain
Identification of Possible Trigeminal Neuralgia
Trigeminal neuralgia (TN) is a severe type of non-dental orofacial pain that can feel like sudden electric shocks in the face and is often mistaken for tooth pain or other dental problems.
- Conditions
- Trigeminal Neuralgia (TN), Orofacial Pain, Dental Pain, Questionnaire
- Trial name
- IDTN (NCT07453511)
- Testing
- Completion of the IDTN Questionnaire
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- University College, London
Education, Medicine
Musicians' Health Education in D-A-CH
Professional musicians are often exposed to significant physical and psychological strain. Long hours of playing, high muscle tension in the head and neck area, and performance-related stress can lead to problems such as…
- Conditions
- Education, Medicine, Dentistry, Orofacial Pain
- Trial name
- MUSED-DACH (NCT07443930)
- Where
- Germany
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen
Chronic Orofacial Pain, Temporomandibular Disorder (TMD)
Orofacial Pain Self-management: Personality Moderation Effect
The objective of this clinical trial is to study the effect of self-management on pain perception in patients with chronic orofacial pain and temporomandibular disorders (TMD) comparing it with the conventional treatment proposed…
- Conditions
- Chronic Orofacial Pain, Temporomandibular Disorder (TMD), Temporomandibular Disorders (TMD), Temporomandibular Dysfunction (TMD)
- Trial name
- NCT06932406
- Testing
- Self-management intervention, Clinical Practice Guideline Intervention
- Where
- Spain
- Volunteers
- 98 people
- Sponsor
- Fundación Universidad Católica de Valencia San Vicente Mártir
Temporomandibular Disorder
The Frequency Forward Head Posture in Subjects With Temporomandibular Disorder
The aim of this study was to verify the frequency of the forward head posture in subjects with temporomandibular disorder and to compare them with control group
- Trial name
- NCT00743223
- Testing
- The measure of the cervical posture
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Federal University of Mato Grosso
Muscular TMD
Effect of Different Oral Splints on the Maximum Bite Force in TMD Patients
The goal of this clinical trial is to evaluate whether three different types of intraoral splints can increase maximal voluntary mandibular clenching force in adults diagnosed with myogenous temporomandibular disorders (TMD).
- Trial name
- NCT07016256
- Testing
- intraoral devices
- Where
- Chile
- Volunteers
- 150 people
- Sponsor
- Universidad Vina del Mar
TMD/Orofacial Pain, Muscle Spasm
Dry Needling for Temporomandibular Disorder
This randomized controlled trial investigates the clinical effectiveness of dry needling in individuals with myofascial temporomandibular disorder (TMD).
- Trial name
- DN-TMD (NCT07123883)
- Testing
- Dry Needling
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Atlas University
Temporomandibular Disorders (TMD), Orofacial Pain
Telemonitoring for TMD-Related Pain
This prospective randomized clinical trial evaluates the effectiveness of a structured telemonitoring protocol as an adjunct to conservative management in patients with temporomandibular disorder (TMD)-related orofacial pain.
- Conditions
- Temporomandibular Disorders (TMD), Orofacial Pain, Myofacial Pain Syndromes, Myalgia of Mastication Muscle
- Trial name
- NCT07764770
- Testing
- Structured Telemonitoring, Conservative Management
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University Magna Graecia
Orofacial Pain, Orofacial Edema
Evaluation of Dental Emergency Treatments During COVID19 Crisis
"For 12 years, the odontology service of the Pitié-Salpêtrière hospital group (GHPS) has been responsible for day and night dental emergency care.
- Conditions
- Orofacial Pain, Orofacial Edema, Dental Trauma, Oral Infection
- Trial name
- URGDENTCOVID (NCT04354272)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 499 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bruxism, Temporomandibular Joint Disorders
Aspects Associated With Obstructive Sleep Apnea, Bruxism and Orofacial Pain
This study evaluated the influence of the sleep bruxism (SB), awake bruxism (AB) and obstructive sleep apnea syndrome (OSAS) on the signs and symptoms of temporomandibular disorders (TMD).
- Conditions
- Bruxism, Temporomandibular Joint Disorders, Obstructive Sleep Apnea Syndrome
- Trial name
- NCT03766464
- Testing
- Evaluation of TMD and pain sensitivity, Evaluation of SB, Evaluation of AB
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Persistent Idiopathic Facial Pain
Atypical Orofacial Pain Diagnostics and Differentiation.
Orofacial pain is diagnosed for more than 1.9 percent of general population and for 0.3 percent origin of the facial pain is unknown.
- Trial name
- NCT04775758
- Testing
- Self-evaluating questionnaires, iMotions analysis platform
- Where
- Lithuania
- Volunteers
- 150 people
- Sponsor
- Lithuanian University of Health Sciences
Cleft Lip Palate, Orofacial Cleft
Effect of Opioid-Free vs Opioid-Based Anesthesia on Postoperative Pain and Emergence Agitation in Children Undergoing Cleft Surgery
Orofacial clefts are among the most common congenital malformations, affecting approximately 1 in 700-1500 live births worldwide.
- Conditions
- Cleft Lip Palate, Orofacial Cleft, Agitation, Emergence, Analgesia Assessment
- Trial name
- NCT07557576
- Testing
- Ketamine (1 mg/kg), Dexmedetomidine (1-0,8-0,6-0,4 mcg/kg/h), Fentanyl 5 mcg/kg
- Where
- Croatia
- Volunteers
- 90 people
- Sponsor
- Iva Smiljanić
Facial Pain
Capsaicin to Control Pain Following Third Molar Extraction
This study will test the effectiveness of the drug capsaicin in controlling pain after third molar (wisdom tooth) extraction. Capsaicin, the ingredient in chili peppers that makes them "hot," belongs to a class of drugs called…
- Trial name
- NCT00008476
- Testing
- Capsaicin
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Facial Pain, Pain, Postoperative
Effectiveness of Alveogyl and Cutanplast Dressing on Postoperative Pain Following Tooth Extraction: A Clinical Trial
This study aims to assess the post-dental extraction pain following the application of two different dressing materials. Alvogyl® and Absorbable gelatin sponges
- Conditions
- Facial Pain, Pain, Postoperative, Pain, Orofacial
- Trial name
- NCT04779476
- Testing
- Socket Dressing
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- Riyadh Elm University
Orofacial Pain, Bruxism
Effectiveness of Chlorzoxazone Versus Orphenadrine Citrate in Alleviating Bruxism Pain
To evaluate the clinical effectiveness of chlorzoxazone in comparison to orphenadrine Citrate in relieving the orofacial pain in bruxers.
- Trial name
- NCT07109882
- Testing
- Chlorzoxazone, Orphenadrine Citrate
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Temporomandibular Disorders, Orofacial Pain
Genetic Polymorphisms and Their Association With Temporomandibular Disorders
Temporomandibular disorders (TMD) are the most common orofacial pain disorders of non-dental origin with the prevalence of 6.1-10.2%, and incidence of 3.9%.
- Trial name
- GenPolTMD (NCT04694274)
- Testing
- stabilization splint, physical therapy
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Croatian Science Foundation
Temporomandibular Joint Disorders, Myofascial Temporomandibular Disorders
Effect of Propranolol on the Autonomic Nervous System and Muscle Pain
The project's primary purpose is to test the hypothesis that oral administration of a low single dose of β-antagonist propranolol (40 mg) reduces pain sensitivity in patients with masticatory muscle pain.
- Trial name
- NCT01333150
- Testing
- Propranololhydrochlorid
- Where
- 2 sites in Denmark
- Volunteers
- 16 people
- Sponsor
- University of Aarhus