Clinical trials: Orthodontic Aligners
Orthodontic Aligners
The Efficiency of Clear Aligners in Maxillary Molar Distalization: A Randomized Clinical Trial.
The aim of this study is to evaluate the accuracy of clear aligners on the amount of the maxillary molar distalization.
- Trial name
- Aligner (NCT06330571)
- Testing
- Molar distalization by aligners with attachment
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Bone Metabolism, Orthodontic Aligners
Bone Metabolism in Patients Treated With 3d Printed Aligners Versus Thermoformed Aligners
Background: Orthodontic forces induce tissue reactions by triggering perturbations from orthodontic appliances, which lead to the modelling and remodelling of alveolar bone.
- Trial name
- NCT07617571
- Testing
- Directly printed aligners using Tera Harz TA28 resin, PETG thermoplastic sheets
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Orthodontic Aligner Material, Enamel Demineralization
Development of Biofunctional 3D-Printed Orthodontic Aligners With Antimicrobial and Remineralizing Properties
Clear orthodontic aligners are widely used due to their esthetics and patient comfort; however, prolonged wear may promote biofilm accumulation and enamel demineralization.
- Conditions
- Orthodontic Aligner Material, Enamel Demineralization, Dental Biofilm Formation, Clear Aligner Material Properties
- Trial name
- 3D-BIOALIGN (NCT07603427)
- Testing
- Modified 3D-Printed Orthodontic Aligner Resin
- Where
- Iraq
- Volunteers
- 400 people
- Sponsor
- University of Baghdad
Malocclusion, Orthodontic Treatment
Comparison of Single-Layer and Triple-Layer TPU MaxFlex Aligners After Intraoral Use
This study aims to compare two types of clear orthodontic aligner materials used in dental treatment: single-layer and triple-layer thermoplastic polyurethane (TPU) aligners (MaxFlex).
- Conditions
- Malocclusion, Orthodontic Treatment, Clear Aligner Therapy
- Trial name
- TPU-ALIGN (NCT07566533)
- Testing
- Single-Layer Thermoplastic Polyurethane Aligner, Triple-Layer Thermoplastic Polyurethane Aligner
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Ayub Medical College, Abbottabad
Dental Plaque Accumulation, Oral Hygiene in Orthodontic Patients
Comparison of Plaque Removal Efficacy of Different Toothbrushes in Clear Aligner Patients
This study aims to compare the effectiveness of manual and powered toothbrushes in removing dental plaque in patients undergoing clear aligner orthodontic treatment.
- Conditions
- Dental Plaque Accumulation, Oral Hygiene in Orthodontic Patients, Clear Aligner Therapy
- Trial name
- NCT07383636
- Testing
- Manual Toothbrush, Powered Toothbrush
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Mersin University
Orthodontic Pain (D013850), Orthodontic Patient Experience
Comparison of Different Debonding Techniques of Clear Aligner Attachments
The goal of this clinical trial is to compare two different methods for removing clear aligner attachments from tooth surfaces and to evaluate the pain levels and removal times associated with each method.
- Conditions
- Orthodontic Pain (D013850), Orthodontic Patient Experience, Orthodontic Aligners, Orthodontic
- Trial name
- NCT07259642
- Testing
- Adhesive removal plier followed by tungsten carbide bur, Tungsten carbide bur
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Clear Aligner Orthodontic Treatment, Composite Attachment
Tooth Discoloration and Chairside Handling Time (Bonding-Debonding) in Flowable Versus Packable Composites for Clear Aligner Bonded Attachments: A Randomized Clinical Trial
This randomized split-mouth clinical trial aims to compare two different composite materials used for bonding attachments in clear aligner orthodontic therapy.
- Conditions
- Clear Aligner Orthodontic Treatment, Composite Attachment, Color Stability of Enamel
- Trial name
- NCT07234149
- Testing
- flowable nanohybrid Composite Resin, Packable Microhybrid Composite Resin
- Where
- 2 sites in Iraq
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Sulaimani
Orthodontic Aligner, Microbial Colonization
Microbial Colonization in Three Dimensional (3D) Printed Orthodontic Clear Aligners
This study is being done to compare conventional clear aligners with 3D printed clear aligners to assess if there is any significant difference between the microbial colonization of these appliances.
- Trial name
- NCT07143370
- Testing
- Thermoformed clear aligner, 3D printed clear aligner TC-85, 3D printed clear aligner TA-28
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Teeth Straightening, Aligner Therapy
A Study to Compare Nighttime Aligners to Daytime Aligners
The purpose of this research study is to see if Nighttime Aligners (worn 10-12 hours per day or night) are effective and safe for tooth movement and if so, how they compare with the standard Daytime aligners (worn 20-22 hours per…
- Conditions
- Teeth Straightening, Aligner Therapy, Orthodontic Aligner
- Trial name
- NCT06539676
- Testing
- Nighttime Aligners, Daytime Aligners
- Where
- 12 sites in United States
- Volunteers
- 7 people
- Sponsor
- Dentsply Sirona Implants and Consumables
Malocclusion, Clear Aligner Appliance
Impact of Aligner Replacement Protocols on Predictability of Planned Dental Movements: Evaluation of Double Aligner
The study will evaluate the impact of replacing aligners after 7 days with new aligners made of different materials on the predictability of planned dental movements.
- Conditions
- Malocclusion, Clear Aligner Appliance, Orthodontics, Tooth Movement
- Trial name
- NCT06882395
- Testing
- Group 1: FLX aligners for 10 days, Group 3: FLX aligners for 7 days, followed by new FLX aligners for 3 days., Group 2: FLX aligners worn for 7 days, followed by FLX35 aligners for 3 days.
- Where
- Brazil
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Neodent
The Present Study Aimed to Evaluate Root Parallelism in Cases of Anterior Teeth Spacing Treated With Clear Aligner Versus Fixed Orthodontic Appliances, Spacing Between Anterior Teeth
Evaluation of Root Parallelism in Cases of Anterior Teeth Spacing Clear Aligner Versus Fixed Appliances
evaluate root parallelism in cases of anterior teeth spacing treated with clear aligner versus fixed orthodontic appliances
- Trial name
- NCT06803940
- Testing
- clear aligner, orthodontic treatment
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Faculty of Dental Medicine for Girls
Orthodontic Aligners
Difference Between Pressing and Vacuum Techniques in Fabrication of Orthodontic Aligners in Cases With Spacing: A Cross-sectional Study
This cross sectional study is aiming to compare 2 techniques of clear aligners fabrication identifying which is better.
- Trial name
- NCT06231875
- Testing
- Press
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Orthodontic Aligners
Difference Between Pressing and Vacuum Techniques in Fabrication of Orthodontic Aligners in Cases With Crowding: A Cross-sectional Study
This cross sectional study is aiming to compare 2 methods of clear aligner fabrication.
- Trial name
- NCT06231888
- Testing
- Aligner
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University