Clinical trials: Orthodontic Appliances
Pain, Anxiety
Comparison of Subjective Experiences Between Patients Receiving Clear Aligners or Fixed Appliances
This study aimed to compare experiences between adult patients receiving clear aligners and fixed appliances during the initial stage of orthodontic treatments.
- Conditions
- Pain, Anxiety, Quality of Life
- Trial name
- NCT03656471
- Testing
- clear aligners or fixed appliances
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Orthodontic Appliances, Low-Level Light Therapy
Photobiomodulation on Molar Verticalization With Mini-implant
The objective of this study will be to evaluate the effect of photobiomodulation on the acceleration of the orthodontic movement of molar verticalization and its effect on pain and inflammation of the periodontal tissues.
- Trial name
- NCT04036539
- Testing
- Placement of the mini-implant and verticalization
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Impacted Canines
Comparing a Novel Closed Exposure Technique to a Conventional Method for Palatally Impacted Maxillary Canines
A multi-center Randomized Clinical Trial, (RCT) on treatment effectiveness of two different closed surgical exposure techniques, one including additional bone removal and a second conventional without removal of additional bone…
- Trial name
- PDC (NCT06833034)
- Testing
- The novel surgical method, The conventional surgical method
- Where
- 2 sites in Sweden
- Volunteers
- 66 people
- Sponsor
- Malmö University
Malocclusion, Angle Class I, Malocclusion; Displaced or Missing Teeth
Comparison Between Clear Aligners and Traditional Fixed Appliances in the Treatment of Four-premolar-extraction Cases
Patients who have severe crowding that require four premolars extraction will be treated in this study. The efficacy of the clear aligners and vestibular fixed appliances will be assessed.
- Conditions
- Malocclusion, Angle Class I, Malocclusion; Displaced or Missing Teeth, Crowding
- Trial name
- NCT03645356
- Testing
- Fixed Appliances, Clear Aligners
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Orthodontic Appliance Complication, Tooth Demineralization
Fluoride Delivery to Prevent White Spots During Orthodontic Treatment
The aim of this 2-armed, parallel, randomised, controlled trial is to assess the effect of different ways of applying fluoride to teeth on the formation of white spots (enamel demineralisation), during orthodontic treatment with…
- Trial name
- FL4OWS (NCT05005689)
- Testing
- Fluoride mouthwash (0.05%; 225ppm)., Tooth Mousse Plus
- Where
- United Kingdom
- Volunteers
- 130 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Orthodontic Tooth Movement
GCF Volume Changes in Aligners and Fixed Appliances
Orthodontic tooth movement induces biological responses in periodontal tissues that can be reflected by changes in gingival crevicular fluid (GCF).
- Trial name
- GCF-OTM (NCT07480538)
- Testing
- Clear Aligner Therapy, Fixed Appliance
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Inflammation Gum, White Spot Lesion
Air-polishing With Erythritol During Orthodontic Tretament
Patients with multi-bracketed fixed orthodontic treatment are at increased risk of developing white spot lesions (WSL) and gingivitis. Various preventive strategies have been examined to prevent the development of WSLs.
- Trial name
- AirPort (NCT05989750)
- Testing
- Ultrasonic scaler, Air-Flow Prophylaxis Master
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Catherine Giannopoulou
Gingival Inflammation
Evaluation of Anti Bacterial Effect of Titanium Dioxide Nanoparticles on Baseplates of Twin Block
Background The objective of this study was to evaluate the antibacterial effect of Titanium dioxide nanoparticles incorporated into the acrylic baseplates of maxillary part of twin block appliances in orthodontic patients during…
- Trial name
- NCT06051487
- Testing
- titanium dioxide nanoparticles in test group
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Orthodontic Appliance, Debonding
Comparison of Two Orthodontic Clean-Up Protocols
Orthodontic clean-up following debonding remains a technically demanding procedure, with documented risks of enamel roughening, microdefects, discoloration, and increased plaque retention.
- Conditions
- Orthodontic Appliance, Debonding, Case-control Study
- Trial name
- NCT07304310
- Testing
- Two-step ultrasonic protocol, One-step clean-up protocol
- Where
- Italy
- Volunteers
- 142 people
- Sponsor
- IRCCS San Raffaele
Orthodontic Pain (D013850), Pain Management (D016146)
A Randomized Clinical Trial of the Effectiveness of Acupressure in Relieving Orthodontic Pain
Orthodontic treatment with fixed appliances often causes pain, which peaks within 24 hours after archwire placement and lasts for several days.
- Conditions
- Orthodontic Pain (D013850), Pain Management (D016146), Acupressure (D056351), Analgesics, Non-Narcotic (D000700)
- Trial name
- NCT06812936
- Testing
- Acetaminophen, Acupressure
- Where
- Iraq
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Orthodontic Appliance Complication
Effect of Moringa Oleifera Mouthwash
Improvement of oral hygiene maintenance is very important during fixed orthodontic appliance treatment to prevent the degenerative effects.
- Trial name
- NCT05191069
- Testing
- Moringa Oleifera Mouthwash
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Malocclusion
Orthodontic Treatment With a Part-Time Wearing Esthetic Removable Appliance
The trial is aimed to investigate an orthodontic treatment with a new removable-part-time-wearing appliance, based on "High-Tech" technology.
- Trial name
- NCT00485602
- Testing
- orthodontic treatment with "Rafenalign" appliance
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Class III Malocclusion
Treatment of Skeletal Class III Malocclusion Using Orthodontic Removable Traction Appliance
This experimental study aims to evaluate the efficiency of the orthodontic removable traction appliance in the treatment of skeletal class III malocclusion.
- Trial name
- NCT03172442
- Testing
- Vacuum plate, Rapid maxillary expander, Class III elastics
- Where
- Syria
- Volunteers
- 22 people
- Sponsor
- Damascus University
Orthodontic Appliance Complication
Evaluation of Periodontal Ligament Distraction Using a Modified Surgical Technique for Retraction of Maxillary Canines
Surgical modification technique try to get bodily movement during upper canine retraction.
- Trial name
- [PLD] (NCT03535285)
- Testing
- Periodontal ligament distraction
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Full Mouth Plaque Score (FMPS)
Effectiveness of Autobrush® Versus Manual Toothbrush Among Adolescents With Fixed Orthodontic Appliances
This study is a randomized crossover clinical trial designed to compare the effectiveness of a U-shaped automatic toothbrush (Autobrush®) versus a conventional manual toothbrush in reducing dental plaque among adolescents…
- Trial name
- NCT07537790
- Testing
- U-shaped toothbrush (Autobrush®), Manual regular toothbrush
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Shahad Abudawood
Malocclusion, Open Bite
Anterior Open Bite Treatment With Bonded Spurs Associated With Build-ups Versus Conventional Bonded Spurs
This study compares the dentoalveolar and skeletal effects of bonded spurs associated with build-ups versus conventional bonded spurs in the early treatment of anterior open bite patients.
- Trial name
- NCT03702881
- Testing
- Bonded Spurs associated with posterior build-ups, Conventional bonded spurs
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo
Orthodontic Appliance Complication, Orthodontic Appliance Design
Periodontal and Orthodontic Outcomes of Straight vs. Looped Fixed Retainers
The goal of this split-mouth, head-to-head, randomized controlled trial is to compare the effects of a fixed straight retainer with the V- loop bonded retainer on periodontal health in patients with the requirement of continuous…
- Conditions
- Orthodontic Appliance Complication, Orthodontic Appliance Design, Orthodontic Treatment
- Trial name
- NCT05644119
- Testing
- V- loop Bonded Orthodontic Retainer, Straight Wire Retainer
- Where
- Saudi Arabia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Class II Division 1 Malocclusion
Study to Measure the Effect of Part Time Versus Full Time Orthodontic Appliance Wear
The aim of this study is to assess skeletal (bone) and dental (teeth) changes occurring following wear of a twin block functional appliance (removable brace which postures the lower jaw forward to improve a discrepancy between…
- Trial name
- NCT02190630
- Testing
- Modified Clark Twin Block
- Where
- United Kingdom
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Orthodontic Appliance, Orthodontic Appliances
Short-term Stability of Tooth-borne vs Bone-borne Maxillary Expansion: A Parallel Cohort Study
This prospective parallel cohort study aimed to compare the short-term stability of maxillary expansion achieved with tooth-borne (Hyrax) and bone-borne expanders.
- Conditions
- Orthodontic Appliance, Orthodontic Appliances, Orthodontic Relapse
- Trial name
- NCT06916299
- Testing
- dental casts, tooth-borne expander insertion, miniscrew and bone-borne expander insertion
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- University of Roma La Sapienza
Class III Malocclusion, Cross Bite
Evaluation of Pain, Discomfort and Acceptance During the Orthodontic Treatment of Class III Malocclusion
The aim of this study is to evaluate the levels of pain, discomfort and acceptance between two treatment modalities of Class III correction of growing patients in the late mixed dentition period.
- Conditions
- Class III Malocclusion, Cross Bite, Orthodontic Appliance Complication
- Trial name
- NCT03976635
- Testing
- Removable Mandibular Retractor, Bone-anchored intermaxillary traction
- Where
- Syria
- Volunteers
- 38 people
- Sponsor
- Damascus University