Clinical trials: Orthodontic Extraction
Dental Crowding, Alveolar Bone Loss
Bone Level Changes Using Clear Aligners Compared to Fixed Appliances in Non-Extraction Treatment of Adults
This study compares two common ways of straightening teeth in adults who have mild-to-moderate crowding of the lower front teeth and do not need any teeth removed: clear aligners and traditional fixed braces.
- Conditions
- Dental Crowding, Alveolar Bone Loss, Malocclusion
- Trial name
- NCT07716007
- Testing
- Fixed orthodontic appliance, Clear aligners
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Gingival Clefts, Extraction Socket
Gingival Clefts and Orthodontic Movement
Clefts or invaginations of the gingival tissue are a frequent finding during orthodontic space closure after extraction of a tooth. They occur in about 35% of the cases.
- Conditions
- Gingival Clefts, Extraction Socket, Orthodontic Movement
- Trial name
- NCT01402323
- Testing
- time point of tooth extraction
- Where
- Austria
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Malocclusion
Effect of Cyclic Loading (Vibration) on Orthodontic Tooth Movement
To gather data indicating whether or not the OrthoAccel device speeds tooth movement in people who use orthodontics (braces).
- Trial name
- NCT00830947
- Testing
- OrthoAccel Device
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- OrthoAccel Technologies Inc.
Malocclusion, Corticotomy
Evaluation of Corticotomy-Assisted Canine Retraction Rate
The goal of this split-mouth randomized clinical trial is to evaluate the effectiveness of corticotomy on maxillary canine retraction rate compared to conventional orthodontic techniques.
- Conditions
- Malocclusion, Corticotomy, Canine Retraction, Orthodontic Tooth Movement
- Trial name
- BMU/2026/8506 (NCT07879066)
- Testing
- Experimental: Corticotomy¬-Assisted Canine Retraction, Active Comparator / Control: Conventional Canine Retraction
- Where
- Bangladesh
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tanzila Rafique
Frequency of Root Paralellism
Assessment of Root Parallelism Following Orthodontic Treatment in Adolescent vs Adult Patients Treated With Maxillary First Premolar Extraction
Panoramic radiographs of finished orthodontic cases will be collected after fulfilling the inclusion and exclusion criteria. Then the collected data will be divided into two groups according to age either adolescent (12-18 years…
- Trial name
- NCT04139174
- Testing
- first premolar extraction and complete canine retraction.
- Volunteers
- 180 people
- Sponsor
- Cairo University
Dental Crowding, Dental Occlusion, Traumatic
Exploration of the Utility of Dental-dedicated MRI for Dentistry
This description observational research is comparative in design, that is comparing existing standard clinical dental images, not obtained in this study, to test (i.e., ddMRI) images.
- Conditions
- Dental Crowding, Dental Occlusion, Traumatic, Endodontic Disease, Orthodontic Treatment
- Trial name
- NCT06948162
- Testing
- dental-dedicated MRI (ddMRI)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Healthy, Maxillary First Premolar Tooth Extraction
Gingival Crevicular Fluid Characterization During Orthodontic Treatment
During Orthodontic tooth movement, teeth are moved through alveolar bone under applied forces. The applied mechanical loading force must be transferred to the alveolar bone via periodontal ligament (PDL).
- Conditions
- Healthy, Maxillary First Premolar Tooth Extraction, Canine Retraction
- Trial name
- NCT04226469
- Testing
- Tooth movement
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Chicago
Orthodontic Appliance Complication
Assessment of Pain When Removing Metallic Brackets for Orthodontic Patients Using Two Removal Methods
Patients at the Orthodontic Department of the University of Damascus Dental School will be examined, and subjects who meet the inclusion criteria will be included.
- Trial name
- NCT06873503
- Testing
- Bracket removal using a Weingart plier with the mouth open, Biting on a cotton roll during brakcet removal
- Where
- Syria
- Volunteers
- 36 people
- Sponsor
- Damascus University
Debonding, Orthodontic Brackets
Does the Pain Experienced During Orthodontic Treatment and Bracket Removal Depend on the Architecture of the Bracket?
The present research aimed to thoroughly investigate the impact of bracket architecture on pain perception during active treatment, debonding, and adhesive removal.
- Trial name
- Debonding (NCT06324162)
- Testing
- bracket removal pliers, LODI
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Piotr Fudalej
White Spot Lesion of Tooth, Gingival Inflammation
EFFECTIVENESS of WATER FLOSS in PLAQUE REMOVAL and PREVENTION of WHITE SPOT LESIONS in ORTHODONTIC PATIENTS: a RANDOMISED CONTROLLED CLINICAL TRIAL
This clinical trial aims to learn if water floss is as efficient as other interdental cleaning tools and can prevent plaque accumulation and white spot lesions (WSLs) in orthodontic patients.
- Conditions
- White Spot Lesion of Tooth, Gingival Inflammation, Gingival Bleeding, Dental Plaque
- Trial name
- WATER FLOSS (NCT06752291)
- Testing
- water flosser
- Where
- Malaysia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Thin-gingiva
Effect Of Injectable PRF And Microneedling In Patient Undergoing Orthodontic Treatment
To evaluate the effect injectable platelet rich fibrin (i-PRF) along with microneedling on gingival thickness in patients with thin gingival phenotype undergoing non extraction fixed orthodontic treatment
- Trial name
- NCT05449925
- Testing
- Injectable PRF and Microneedling
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Angle Class I
Effectives of Non-extraction Orthodontic Treatment of Angle Class I Malocclusion
Introduction: The investigators aimed to evaluate the effectiveness of non-extraction orthodontic treatment for Angle class I malocclusion.
- Trial name
- NCT06638983
- Testing
- Non-extraction Orthodontic Treatment of Angle Class I Malocclusion
- Where
- Vietnam
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Can Tho University of Medicine and Pharmacy
Malocclusion, Class I/II, Crowding, Tooth
Treatment Outcome of Clear Aligner and Traditional Fixed Appliances in Four Premolar Extraction Cases
Patients with severe crowding requiring the extraction of four premolars will be enrolled in this study. The degree of apical root resorption associated with using the clear aligner technique compared with vestibular fixed…
- Trial name
- NCT07236775
- Testing
- Clear Aligners, Traditional fixed appliances
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Crowding of Anterior Maxillary Teeth
Repeated Injections of i-PRF for Decreasing Root Resorption After the Orthodontic Treatment.
Mandibular incisor crowding is a frequent issue that prompts many adults to seek orthodontic treatment. The treatment may enhance patients' quality of life, facilitate dental plaque control, and improve the quality of periodontal…
- Trial name
- NCT07352241
- Testing
- 4-time i-PRF injection group, Saline injection
- Where
- Syria
- Volunteers
- 36 people
- Sponsor
- Damascus University
Immediate Dental Implant Loading
The Preliminary Application of Socket-shield Technique in Orthodontic Extraction and Fixed Orthodontic Treatment
Background This study was conducted to investigate the clinical efficacy of Socket-Shield Technique on the first premolar bone preservation in Orthodontic Extraction Treatment.
- Trial name
- NCT06510621
- Testing
- Socket-Shield Technique
- Where
- China
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Effect of Premolars Extraction on Bite Force
Analysis of Bite Force Distribution After Premolars Extraction by Using T-scan Analysis System
This study aims to assess the effect of first premolars extraction during orthodontic treatment bite force during the excursive mandibular movements using a digital occlusal analysis system.
- Trial name
- NCT07253337
- Testing
- T-scan analysis for bite force distribution
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Suez Canal University
Skeletal Class I Non-extraction Patients With Dental Crowding
Evaluation of Dentoalveolar Changes of Clear Aligners Versus Fixed Orthodontic Appliances on Skeletal Class I Non-extraction Patients With Dental Crowding
To evaluate dentoalveolar changes of clear aligners versus fixed orthodontic appliances on skeletal class I non-extraction patients with dental crowding.
- Trial name
- NCT07090746
- Testing
- Clear aligner, Fixed orthodontic appliance
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Mansoura University
Gummy Smile, Orthodontic Treatment
Vertical Gingival Display Changes Associated With Upper Premolars Extraction
To investigate and compare vertical gingival display (VGD) changes associated with upper premolars extraction during orthodontic treatment.
- Trial name
- NCT04375540
- Testing
- Upper first premolars extractions, Upper second premolars extraction
- Where
- Jordan
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Skeletal Open Bite, Vertical Maxillary Excess
Treatment of Skeletal Open Bite With Open Bite Activator and Skeletal Anchorage-Supported Vertical Elastics
This study evaluated a new treatment approach for skeletal open bite in growing individuals using an open bite activator combined with anterior skeletal anchorage-supported vertical elastics.
- Conditions
- Skeletal Open Bite, Vertical Maxillary Excess, Hyperdivergent Growth Pattern, Long Face Syndrome
- Trial name
- SOBT (NCT06936371)
- Testing
- Open Bite Activator with Skeletal Anchorage-Supported Vertical Elastics
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ankara University
Orthodontic Appliance
Speed of Premolar Extraction Space Closure: Every Visit Replacement of Working Archwire
The aims of this trial were to assess the effect of changing 0.019X0.025-inch SS working archwire monthly on the rate of space closure, to compare the frictional resistance of unchanged and new working archwires in-vitro, and to…
- Trial name
- NCT04549987
- Testing
- Space closure without changing working archwire monthly, Space closure withchanging working archwire monthly
- Where
- Jordan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology