Clinical trials: Orthodontic Movement
Cytokine Measurements, Orthodontic Space Closure
Biological Markers Evaluation of Accelerated Tooth Movement
Gingival Crevicular Fluid samples will be collected using periopapers after accelerated tooth movement technique, results will be assessed with biomarkers levels done using ELISA Assays
- Conditions
- Cytokine Measurements, Orthodontic Space Closure, Tooth Movement
- Trial name
- NCT02887547
- Testing
- micro-osteoperforation
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Orthodontic Tooth Movement
Impact of Gingival Crevicular Fluid microRNAs on Orthodontic Tooth Movement
A split-mouth study is conducted in order to evaluate the impact of orthodontic movement on the expression of gingival crevicular fluid miRNAs related to inflammation and osteoclastogenesis during canine distalization following…
- Trial name
- NCT06023433
- Testing
- Elastomeric powerchain
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Catania
Dental Malocclusion
Effect of Low Level Laser on Orthodontic Canine Retraction
The aim of this study was to determine whether orthodontically moved maxillary canines exposed to two different protocols and dosage of LLLT exhibited differences in amount and rate of orthodontic tooth movement.
- Trial name
- NCT04381442
- Testing
- Low Level Laser Therapy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Orthodontic Appliance Complication
Assessment of the Effectiveness of Corticision Combined by Selfligating Bracket System on the Acceleration of Orthodontic Tooth Movement; A Prospective Clinical Study
the goal of this clinical trial is to assess the effectiveness of the corticision with self-ligating bracket system on the acceleration of orthodontic tooth movement.The main question it aims to answer is whether or not there…
- Trial name
- NCT05604612
- Testing
- Corticision
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Orthodontic Appliance Complication
Low Level Laser Therapy Applied in Orthodontic Tooth Movement
Currently, orthodontic treatment takes 2-3 years.. If we accelerate tooth movement by low energy laser therapy, we could reduce treatment time.
- Trial name
- NCT05695053
- Testing
- Low Level Laser Therapy
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Intrabony Periodontal Defect
Comparison of the GTR Procedure Alone and in Combination With Immediate OTM
The aim is to evaluate in a prospective, randomized, controlled clinical study the healing of a GTR procedure, when it is combined with an immediate orthodontic tooth movement or used alone.
- Trial name
- NCT04896450
- Testing
- Guided tissue regeneration (GTR), Orthodontic tooth movement (OTM)
- Where
- Hungary
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Malocclusion, Canine Retraction
Maxillary Canine Retraction Using Stainless Steel and Titanium-molybdenum Alloy Wires in TAD-supported Segmental Mechanics
The goal of this randomized clinical study is to compare the effectiveness of stainless steel (SS) and titanium-molybdenum alloy (TMA) wires for maxillary canine retraction using TAD-supported segmental mechanics.
- Conditions
- Malocclusion, Canine Retraction, Orthodontics, Tooth Movement Techniques
- Trial name
- NCT07645417
- Testing
- A titanium-molybdenum alloy reverse-closing loop, A stainless steel reverse closing loop
- Where
- Bangladesh
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Tanzila Rafique
Dental Crowding, Vibrational Force
Intermittent Vibrational Force and Orthodontic Tooth Movement
The aim of this study is to compare the clinical efficiency of conventional fixed appliance orthodontic treatment with that supplemented by the daily application of cyclic forces to the dentition via a removable (AcceleDent)…
- Conditions
- Dental Crowding, Vibrational Force, Fixed Orthodontic Appliances
- Trial name
- NCT02314975
- Testing
- AcceleDent vibrational device, Fixed appliance only
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- King's College London
Orthodontic Tooth Movement
Acceleration of Tooth Movement Using PRP and Photobiomodulation With Clear Aligners
This study compares the effectiveness of two adjunct therapies- photobiomodulation (low-level laser therapy) (PBM) and localized platelet-rich plasma (PRP) injections in accelerating orthodontic tooth movement.
- Trial name
- NCT07795073
- Testing
- Platelet Rich Plasma (PRP) injection, photobiomodulation (PBM) Therapy, clear aligner(12-hour wear protocol)
- Where
- Yemen
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sana'a University
Class II Malocclusion, Orthodontic Tooth Movement
Effect of Photobiomodulation on Orthodontic Tooth Movement
This study evaluated whether photobiomodulation (PBM), a form of low-level light therapy, can accelerate orthodontic tooth movement during canine distalization in adult patients undergoing fixed orthodontic treatment.
- Trial name
- NCT07390357
- Testing
- 635-nm photobiomodulation
- Where
- Poland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Orthodontics
Study of the Use of Orthopulse Photobiomodulation
This PMCF study evaluates the safety and performance of OrthoPulse photobiomodulation to accelerate tooth movement during alignment with fixed appliances.
- Trial name
- NCT05650359
- Testing
- OrthoPulse, No intervention
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Biolux Technology GmbH
Clear Aligner Appliance
Evaluation of the Efficacy of Injectable Platelet-rich Plasma in Tooth Movement Acceleration With Clear Aligner
Aim of the study is evaluation of the efficacy of injectable platelet-rich plasma in orthodontic tooth movement acceleration with clear aligner
- Trial name
- NCT07103551
- Testing
- Platelet-rich plasma
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Effect of Low Level Laser Versus Low Intensity Pulsed Ultra Sound on Rate of Different Orthodontic Tooth Movement by Millimeter
Influence of Low-level Laser Therapy Versus Low-intensity Pulsed Ultrasound on Different Orthodontic Tooth Movements
The aim of this prospective clinical project will be to compare the effect of low-level laser therapy versus low intensity pulsed ultrasound on the rate of different orthodontic tooth movements
- Trial name
- NCT06026930
- Testing
- low-level laser therapy
- Where
- Egypt
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Malocclusion
The Effect of Ultrasound on Orthodontic Tooth Movement
To study whether or not the Aevo System™ medical device enhances the rate of tooth movement in human subjects who use orthodontic braces.
- Trial name
- NCT01828164
- Testing
- Ultrasound
- Where
- 5 sites in Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- SmileSonica Inc.
Orthodontic Tooth Movement
Clinical Trial to Assess the Efficacy of Reducing the Aligners' Wear Protocol
The hypothesis of this project is that replacing the current 7-day wear protocol with a 3-day wear protocol, while integrating less tooth movement per aligner (reduce the amount of activation per aligner) may produce more…
- Trial name
- NCT05905224
- Testing
- Invisalign 7-day wear protocol, Invisalign 3-day wear protocol
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Florida
Maxillary Transverse Deficiency Class I Malocclusion Vitamin D Deficiency Orthodontic Tooth Movement Adolescent Health
Effect of Serum Vitamin D on MARPE Treatment Response
A total of 30 patients are planned to be included in the study during the first half of 2025, who will apply to the clinic. In our clinical routine, approximately 30% of RME patients are treated using the MARPE method.
- Trial name
- NCT06943443
- Testing
- Miniscrew-Assisted Rapid Palatal Expansion (MARPE) Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Crowding of Anterior Mandibular Teeth
Evaluating the Efficacy of Micro-Osteoperforations Technique on the Orthodontic Tooth Movement Acceleration in Moderate Mandibular Anterior Crowding Cases Treated With Clear Aligners
Patients with moderate mandibular anterior crowding will be treated in this study. The efficacy of micro-osteoperforations technique by special drill in accelerating orthodontic tooth movement during clear aligners therapy will…
- Trial name
- NCT05492773
- Testing
- Micro-osteoperforations Technique, Active comparater
- Where
- Syria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hama University
Orthodontic Tooth Movement
Effectiveness of Olive Oil Local Application in Orthodontic Patients.
The large body of evidence supports the chemotherapeutic potential of substances found in Olive Oil (OO), acting on different sides, such as inflammation, oxidative damage, and even epigenetic modulation.
- Trial name
- NCT05040620
- Testing
- Olive Oil Topical Oil
- Where
- Egypt
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Minia University
Tooth, Impacted, Molar, Third
The Role of Matrix Metalloproteinases (MMPs) in Orthodontic Tooth Movement
The purpose of this study is to test whether the two MMPs can be up-regulated during orthodontic treatment. Alveolar bone samples will be collected from partially impacted third molars after orthodontic uprighting for different…
- Trial name
- NCT00154518
- Testing
- Orthodontic treatment
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Malocclusion
Comparison of Orthodontic Molar Protraction With and Without Adjunctive Surgery
This study will compare orthodontic molar protraction with and without adjunctive periodontally accelerated osteogenic orthodontic (PAOO) surgery prior to orthodontic tooth movement.
- Trial name
- PAOO (NCT03794726)
- Testing
- Orthodontic Molar Protraction and PAOO, Orthodontic Molar Protraction
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham