Clinical trials: Orthognathic Surgery
Maxillofacial Abnormalities
Impact of Maxillomandibular Deformities on Individuals' Nutritional Status
This cross-sectional study explores the influence of various types of maxillomandibular deformities on the nutritional status of individuals.
- Trial name
- NCT05936476
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Marmara University
Mandibular Hypoplasia
Comparing Stability and Cost-Effectiveness of 3 Bicortical Screws Vs Adjustable Plate and 2 Bicortical Screws in Fixation of BSSRO
In this current study a comparison between 3 positional screws versus the adjustable plating system in conjunction with 2 positional screws. The patients will be selected to have retrognathic mandible requiring advancement.
- Trial name
- NCT02950727
- Testing
- 3 bicortical screws, adjustable plate and 2 bicortical screws
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Joseph Van Sickels
Pain, Postoperative
Does Preventive Dexketoprofen Reduce Pain After Orthognathic Surgery
Background The purpose of this study was to evaluate the effect of a single-dose intravenous dexketoprofen administration for preventive analgesia on postoperative pain and reducing swelling in double jaw surgery.
- Trial name
- NCT05303688
- Testing
- iv dexketoprofen trometamol (Arveles 50mg/2mL; UFSA, İstanbul, Turkey), Steril Salin (control)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Tranexamic Acid, Orthognathic Surgery
The Effects of Tranexamic Acid on Blood Loss During Orthognathic Surgery
This study seeks to answer the question: Does a single pre-operative dose of tranexamic acid have a statistically significant reduction in blood loss during orthognathic surgery? If it does, this drug may begin to be used…
- Trial name
- TXA-OMFS (NCT03433144)
- Testing
- Tranexamic Acid Injectable Solution
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nick Emanuele
Enhanced Recovery After Surgery, Hospital Stay
The Impact of Enhanced Recovery After Surgery in Orthognathic Surgery
Aim: Orthognathic surgeries are generally associated with blood loss, swelling, postoperative nausea vomiting (PONV), and pain. The aim of this study is to improve postoperative outcome in patients undergoing orthognatic…
- Conditions
- Enhanced Recovery After Surgery, Hospital Stay, Postoperative Nausea and Vomiting, Pain, Postoperative
- Trial name
- NCT04596774
- Testing
- Traditional Approach, Enhanced Recovery After Surgery (ERAS) Approach
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Orthognathic Surgery
Prediction Accuracy of Dolphin 3D in Bimax Surgery for Class III
Patients with class III dentofacial deformity who are in need of surgical correction are now able to see the potential changes to their faces before the actual operation.
- Trial name
- NCT04353635
- Testing
- dolphin 3d
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Orthognathic Surgery, Postural Balance
Effect of Orthognathic Surgery on Plantar Pressure and Posture
Orthognathic surgery leads to changes in the three-dimensional position of the jaws, which may result in alterations in head and neck posture as well as overall body posture.
- Trial name
- NCT07350681
- Testing
- Orthognathic Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ayşenur Dindar
Discoloration, Tooth
In Vivo Assessment of Natural Tooth Color After Orthognathic Surgery. A Pilot Controlled Clinical Trial
In six consecutive patients planned to receive combined orthodontic-orthognathic surgery natural tooth color on 8 incisors was measured before initiation of the combined treatment (Time Point 1- baseline) and after its completion…
- Trial name
- NCT03657498
- Testing
- Combined orthodontic-orthognathic treatment, Standard orthodontic treatment
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Accuracy, Operation Time
Retrospective Study on the Application of Tooth-bone Dual-support Osteotomy/Location Plate in "Surgery-first" Orthognathic Treatment
The goal of this observational study is to learn the accuracy of tooth-bone dual-support osteotomy/location guide plate compared with conventional CAD/CAM interocclusal splints in "surgery-first" orthognathic surgeries.
- Trial name
- NCT07622758
- Testing
- orthognathic surgery
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College
Cleft Lip and Palate, Maxillary Hypoplasia
Cleft Orthognathic Surgery Versus Distraction Osteogenesis - Which is Better?
Cleft lip and palate patients normally present with a sunken face due to collapse in the middle part of the face and inability of the upper and lower teeth to meet during chewing.
- Trial name
- NCT00930124
- Testing
- Orthognathic surgery, Distraction osteogenesis
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Health-related Quality of Life, Dentofacial Deformities
Cross Cultural Adaptation and Validation of Orthognathic Quality of Life Questionnaire (OQLQ)
The aim of this study was to develop a Spanish version of the Orthognathic Quality of Life Questionnaire (OQLQ) that is conceptually equivalent to the original questionnaire, as well as acceptable, reliable, valid, and responsive…
- Trial name
- NCT04863170
- Testing
- orthognathic surgery
- Where
- Chile
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Hospital Carlos Van Buren
Dentofacial Deformity
Orthognathic Surgery and Postoperative Antibiotic Use
Currently there is debate in the literature as to the recommended length of postoperative antibiotics in patients undergoing orthognathic surgery.
- Trial name
- NCT01823523
- Testing
- Cefazolin, Cephalexin, Clindamycin
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Atlantic Center for Oral and Maxillofacial Surgery
Orthognathic Surgical Procedures
Effect of Proximal Segment Positioning on Condylar Remodeling
This study aims to evaluate postoperative condylar remodeling in patients undergoing bimaxillary orthognathic surgery by comparing two different proximal segment positioning techniques used during mandibular osteotomy.
- Trial name
- NCT07758725
- Testing
- Proximal Segment Rotation, Inferior Border Osteotomy Without Proximal Segment Rotation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
OSA, Malocclusion
Changes of the Upper Airway Volume After Orthognathic Surgery
The aim of the present project is to analyze the impact from orthognathic surgery on the upper airway respiratory volume. The primary objective is comparison of differences in the in the airway changes due to maxillary movements…
- Conditions
- OSA, Malocclusion, Dentofacial Deformities
- Trial name
- NCT05060133
- Testing
- Orthognathic Surgery
- Where
- Sweden
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Lund University Hospital
Orthognathic Surgical Procedures, Piezoelectric Technique
Piezosurgery Versus Conventional Techniques in Orthognathic Surgery
The goal of this randomized double-blinded controlled clinical trial is to determine whether piezosurgery can reduce complications and improve outcomes compared to conventional osteotomy techniques in patients undergoing…
- Trial name
- NCT07174193
- Testing
- Piezosurgery, Conventional techniques
- Where
- 2 sites in Netherlands
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Class III Malocclusion, Root Resorption
Determining the Presence of RAP in Orthognathic Patients and Its Effect on Root Resorption by Biomarkers
A prospective clinical trial to what extent inflammatory biomarkers are affected by the medication after orthognathic surgery in early surgical cases and whether these biomarkers affects the amount of maxillary or mandibular…
- Trial name
- RAP (NCT04823325)
- Testing
- Orthognathic Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Maxillofacial Abnormalities
Mandibular Stability and Dentofacial Deformity
The present study intends to clarify whether there is positional mandibular stability in patients to be submitted to orthognathic surgery.
- Trial name
- NCT01486069
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Cognitive Dysfunction, Postoperative Complications
The Effect of Hypotensive Anesthesia on Cognitive Functions in Orthognatic Surgery
The purpose of this study is to evaluate the effects of maintaining adequate cerebral oxygen saturation on patients undergoing orthognathic surgery.
- Trial name
- NCT06925711
- Testing
- Near-Infrared Spectroscopy (NIRS)
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Medipol University
Accuracy of 3D Printed Titanium Plates Versus 3D Milled Titanium Plates in Genioplasty Orthognathic Surgery, Patient Specific Genioplasty
Accuracy of Patient Specific 3D Printed Titanium Plates Versus Milled Titanium Plates in Genioplasty Orthognathic Surgeries.
To assess accuracy of patient specific 3D printed titanium plates versus 3D milled titanium plates in genioplasty orthognathic surgery
- Conditions
- Accuracy of 3D Printed Titanium Plates Versus 3D Milled Titanium Plates in Genioplasty Orthognathic Surgery, Patient Specific Genioplasty, Accuracy of 3D Printed Titanium Plates Versus 3D Milled Titanium Plates in Genioplasty
- Trial name
- NCT07344441
- Testing
- genioplasty using 3D printed patient specific titanium plates (study group), genioplasty using 3D milled patient specific titanium plates (control group)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dentofacial Deformities, Dentofacial Anomalies [Including Malocclusion] and Other Disorders of Jaw (M26-M27)
Effect of Proximal Segment Positioning on Postoperative Condylar Remodeling in Bimaxillary Orthognathic Surgery
Bimaxillary orthognathic surgery is a surgical procedure that involves simultaneous corrections to both the maxilla (upper jaw) and mandible (lower jaw).
- Trial name
- NCT06897787
- Testing
- manuel positioning group, mandibular basis osteotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University