Clinical trials: Orthopaedic
Healthy Subjects
Balance Effects of Morton´s Extension in Flat Foot
The aim of this study is to simulate the orthopedic treatment called Morton's extension on flat foot patients to check balance effects in standing position.
- Trial name
- NCT06526715
- Testing
- Morton extension
- Where
- Spain
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Mayuben Private Clinic
Orthopedic Disorder of Spine, Artificial Intelligence
Validation of the Utility of an Artificial System for the Large-scale Screening of Scoliosis
Traditional school scoliosis screening approaches remains debatable due to unnecessary referal and excessive cost. Deep learning algorithms have proven to be powerful tools for the detection of multiple diseases; however, the…
- Conditions
- Orthopedic Disorder of Spine, Artificial Intelligence, Scoliosis
- Trial name
- NCT03773458
- Testing
- An artificial system for the screening of scoliosis
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Postoperative Pain
Intrathecal Pethidine Plus Dexamethasone for Distal Lower Orthopedic Surgeries
Bupivacaine is commonly used as a sole agent for spinal anesthesia unlike pethidine. Pethidine (meperidine) is a unique opioid. In addition to its analgesic activity, it also has significant local anesthetic activity.
- Trial name
- NCT05303311
- Testing
- Bupivacaine Hydrochloride, Pethidine plus Dexamethasone
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Simulation Based Medical Education
Optimizing Simulation-Based Training in Orthopedics: Exploring Deliberate Flawed Performance for Dynamic Hip Screw Osteosynthesis
Proximal femoral fractures (PFF) are associated with increased mortality when surgical intervention is delayed, with evidence supporting osteosynthesis within 12 to 24 hours of admission to minimize risk.1, 2 Consequently…
- Trial name
- NCT06729372
- Testing
- Deliberate Flawed Performance, Error Avoidance Training
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Radiation Exposure
A Prospective Study of Radiation Exposure to Surgeons
The purpose of this study is to measure the amount of radiation over a specific period of time that Orthopaedic Surgeons are exposed to while using the mini c-arm fluoroscopy machine.
- Trial name
- NCT00378053
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Infection of Catheter Exit Site, Catheter Related Infection
Alcoholic Chlorhexidine Compared to Povidone Iodine to Limit Perineural Catheter Colonisation
Implementation of perineural catheters may lead to infection by catheter colonization. Catheters may be colonized by the bacteria present on the skin.
- Trial name
- CHLOVEPI (NCT02950246)
- Testing
- perineural catheterization implementation, 2% alcoholic chlorhexidine, povidon iodine
- Where
- France
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Hôpital Raymond Poincaré
Pressure Ulcer
The Effect of Pressure Ulcer Care Package on the Risk of Pressure Ulcer Development
This study aimed to determine the effect of pressure ulcer care package use on the risk of pressure ulcer development due to surgery in patients undergoing orthopedic surgery. It was planned as a randomized controlled study.
- Trial name
- NCT06330506
- Testing
- Pressure ulcer prevention pack
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Work-Related Musculoskeletal Disorders
WRMSDs Among Orthopedic Surgeons
The investigators investigated the prevalence of WRMSDs in Egyptian orthopaedic surgeons.
- Trial name
- WRMSDs (NCT07562126)
- Where
- Egypt
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Cairo University
Orthopedic Disorder, Hip Arthropathy
Iron and Vitamin Supplementation in Hip/Knee Surgery
Randomized controlled trial to evaluate the efficacy of oral iron supplementation plus cofactors in reducing the prevalence of preoperative anemia in a cohort of 60 patients undergoing elective prosthetic hip or knee surgery.
- Conditions
- Orthopedic Disorder, Hip Arthropathy, Knee Arthropathy, Anemia
- Trial name
- NCT04880499
- Testing
- Iron plus folic acid, vitamin B2, B6, B12, C, and E
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Infections
A Multi-Center Protocol for Obtaining and Storing Human Samples for Immediate or Future Microbial, Immune, or Host-Microbe Scientific Study
The intent of this protocol is to salvage human-related material that is normally destined for destruction, so it can be used in infection-related scientific studies.
- Trial name
- NCT00764023
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Southwest Regional Wound Care Center
Trauma, Orthopedic Surgery Complications
The Infected Bone Nonunion and Soft Tissue Defect of Long Bone Treated Simultaneously With Ilizarov Technique
In this retrospective study, the investigators evaluated the clinical and functional results of infected nonunion of the long bone with soft-tissue defects treated simultaneously with Ilizarov technique combining open dressing…
- Trial name
- NCT00846261
- Testing
- Use it to treatment bone nonunion (Ilzarov)
- Where
- China
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Osteoarthritis, Knee, Fractures, Ununited
Modern Methods of Treatment and Diagnosis of Patients With Injuries and Diseases of the Musculoskeletal System
Brief Summary This clinical study investigates the safety and effectiveness of combining advanced regenerative therapies with personalized surgical technology for patients with delayed fracture healing (non-unions), knee…
- Conditions
- Osteoarthritis, Knee, Fractures, Ununited, Arthroplasty, Replacement, Knee
- Trial name
- MTDMS (NCT07628010)
- Testing
- Autologous Mesenchymal Stromal Cells Combined with Platelet-Rich Plasma, Patient-Specific 3D-Printed Surgical Instruments
- Where
- Ukraine
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zaporizhzhiya State Medical University
Chronic Inflammation
Analysis of the Relationship Between the Quantitative Index of Cytokines in the Oral Fluid and Inflammation
The of study is to increase the effectiveness of orthopedic rehabilitation of patients with postoperative jaw defects using various types of replacement structures, taking into account the clinical and morphofunctional…
- Trial name
- NCT05304689
- Testing
- test for quantitative index of interleukins in the oral fluid
- Where
- Russia
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ryazan State Medical University
Puncture, Surgical Gloves
The Effect of Using Double Gloves on Perforation in Orthopedic Surgery
Aim: This study aimed to investigate the effect of using double gloves on perforation in orthopedic surgery. Materials and Method: The randomized controlled experimental study was conducted between 30.11.2021 and 31.03.2022 in…
- Conditions
- Puncture, Surgical Gloves, Orthopedic Disorder
- Trial name
- NCT05928663
- Testing
- double surgical gloves, single surgical gloves
- Where
- Turkey (Türkiye)
- Volunteers
- 1,170 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Orthopedic Disorder
Improve the Quality of Care in Patients With Orthopaedic Disorders
The main objective of the investigators is to improve the quality of care in patients with orthopedic disorders followed in St Luc hospital (Brussels Belgium).
- Trial name
- QualOrtho (NCT02355301)
- Testing
- orthopedic
- Where
- Belgium
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Atelectasis
Perioperative Atelectasis in Orthopaedic Surgery: a Prospective Study
This study aims at comparing a perioperative pulmonary atelectasis score, measured by pulmonary ultrasound, in patients operated undergoing orthopedic surgery under general anesthesia, spinal anesthesia or peripheral nerve block.
- Trial name
- ATELHO (NCT05384795)
- Testing
- Lung ultrasound
- Where
- Switzerland
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Eric Albrecht
Stem Cells, Orthopedic Disorder
Stem Cells After Peripheral Mobilization and Harvest
The proposed study is a controlled laboratory study where stem cell content of bone marrow aspirate will be compared prior to and following pharmaceutical mobilization.
- Trial name
- NCT03381599
- Testing
- Filgrastim Injection
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Andrews Research & Education Foundation
Post Operative Pain
Effect of Preoperative Information About Pain on Postoperative Pain Experience and Patient Satisfaction
Patients are randomized into 2 groups. The intervention group which receives preoperative counseling about pain and a control group which does not receive this counseling.
- Trial name
- epps (NCT03056521)
- Testing
- preoperative information about pain
- Where
- Uganda
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Makerere University
Educational Problems
Perceptions of Orthopedic Prespecialists on Patient-Specific 3D Models.
Background: Three-dimensional (3D) patient-specific anatomical model guidance is a reliable tool in obtaining accurate bony cuts, precise implant placement, and satisfactory surgical results.
- Trial name
- NCT04430270
- Testing
- Survey
- Where
- Turkey (Türkiye)
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Ege University
Athletic Injuries, Sport Injuries
Rise With Resilience
The objective of this study is to investigate differences in postoperative pain, physical health, and mental health outcomes between participants receiving evidence-based mindfulness training and those who do not.
- Trial name
- NCT07217275
- Testing
- Community Resiliency Model (CRM), Control
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Emory University