Clinical trials: Orthopedic
Pain, Acute, Hip Arthropathy
Safety of Ibuprofen After Major Orthopaedic Surgeries
Safety of an eight-day treatment with ibuprofen after primary hip and knee arthroplasties.
- Conditions
- Pain, Acute, Hip Arthropathy, Knee Arthropathy, Safety Issues
- Trial name
- PERISAFE (NCT05575700)
- Testing
- Ibuprofen
- Where
- 11 sites in Denmark
- Volunteers
- 2,904 people
- Sponsor
- Naestved Hospital
Orthopedic Disorder, Hip Arthropathy
Iron Supplementation in Hip/Knee Surgery
Randomized controlled trial to evaluate the efficacy of oral iron supplementation in reducing the prevalence of preoperative anemia in a cohort of 82 patients undergoing elective prosthetic hip or knee surgery.
- Conditions
- Orthopedic Disorder, Hip Arthropathy, Knee Arthropathy, Anemia
- Trial name
- NCT04078880
- Testing
- Sucrosomial iron plus ascorbic acid
- Where
- Italy
- Volunteers
- 82 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Fractures, Open, Fractures, Closed
LOQTEQ® Antibacterial Pre-Market Study
aap001 is a randomized, controlled, subject-blinded, multi-center study to show the safety of the LOQTEQ® antibacterial silver-coated system is non-inferior in comparison with the uncoated LOQTEQ® system
- Conditions
- Fractures, Open, Fractures, Closed, Surgical Site Infection, Fracture of Fibula
- Trial name
- NCT05260463
- Testing
- Implantation
- Where
- 13 sites in Germany
- Volunteers
- 203 people
- Sponsor
- aap Implantate AG
Cartilage Degeneration, Rotator Cuff Tear
Use of MRI Labeling Technique to Track Mesenchymal Stem Cell Survival in Orthopaedic Conditions
The primary objective is to determine whether a surgical intervention involving removing of the calcified cartilage cap in patients with Grade II Kellgren-Lawrence osteoarthritis influences the incorporation of labeled bone…
- Conditions
- Cartilage Degeneration, Rotator Cuff Tear, Osteoarthritis, Knee
- Trial name
- NCT03648463
- Testing
- arthroscopy of the affected knee/ Bone Marrow Concentrate Injection
- Sponsor
- Stanford University
Surgical Site Infection
The Use of Ceftaroline as Surgical Prophylaxis in Surgery With Risk of MRSA Infection
The study is a randomized double-blinded study comparing ceftaroline to standard of care therapy with cefazolin and vancomycin as surgical prophylaxis for high risk orthopedic and cardiac surgeries.
- Trial name
- PREVTAROLINE (NCT02307006)
- Testing
- Ceftaroline, Cefazolin / Vancomycin
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- University of Cincinnati
Orthopedic Disorders, Foot Diseases
Efficacy of Ultrasound-Guided Local Anesthetic Injection Into or Around the Sciatic Nerve for Lower Limb Anesthesia
This study was designed to assess whether the injection of local anesthetic into the nerve (intraneural), as opposed to around it (perineural), requires a shorter time to develop surgical anesthesia of the lower leg.
- Conditions
- Orthopedic Disorders, Foot Diseases, Injuries, Leg, Injuries, Foot
- Trial name
- NCT01999647
- Testing
- Intraneural Injection for Subgluteal Sciatic Nerve Block, Perineural Injection for Subgluteal Sciatic Nerve Block, Femoral Nerve Block
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- University of Parma
Fracture, Trauma
Surgical Treatment Versus Non-surgical Treatment of Ulnar Fractures
The purpose of this study is to determine if surgery using a plate and screws to fix a forearm fracture (ulnar shaft) will improve functional outcome compared to non-operative treatment out to 1 year of follow-up.
- Conditions
- Fracture, Trauma, Ulna Fracture, Orthopedic
- Trial name
- NCT01123447
- Testing
- Open reduction and internal fixation, Closed reduction and short-arm cast
- Where
- 9 sites in Canada, United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Calgary
Upper Extremity, Orthopedic Surgery
Ultrasound-Guided Axillary or Infraclavicular Nerve Block for Upper Limb Surgery
This study aims to detect differences in onset time of brachial plexus (i.e., arm) anesthesia using two different nerve block techniques.
- Conditions
- Upper Extremity, Orthopedic Surgery, Trauma, Forearm Injuries
- Trial name
- NCT00724035
- Testing
- Midazolam, Ropivacaine, Fentanyl
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- University of Parma
Paramedian Spinal Anaesthesia, Real Time Ultrasound Guiding
Paramedian Spinal Anaesthesia : Comparison Between Land-mark Guided Technique and Real-time Ultrasound Guided Technique.
To identify the value of using the ultrasound in applying a commonly used regional anaesthetic procedure (spinal anaesthesia) when compared with the conventional landmark guided approach, regarding the efficiency of the…
- Trial name
- NCT02767076
- Testing
- conventional paramedian spinal anesthesia, ultrasound guided paramedian spinal anesthesia
- Where
- Egypt
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anxiety, Pain
Virtual Reality Pediatric Orthopaedic Outpatient Procedures
The main objective of the study is to evaluate the use of Virtual Reality (VR) in managing pain and anxiety levels during common pediatric orthopaedic outpatient procedures which include: cast application, cast removal, hardware…
- Trial name
- VPRO (NCT03784352)
- Testing
- Virtual Reality
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- British Columbia Children's Hospital
Injury of Foot, Shoulder or Knee, Perineural Analgesia
Postoperative Patient-controlled Perineural Analgesia After Orthopedic Surgery by "Remote Control" Versus "Bedside Care"
Perineural injection of local anesthesic is currently the reference method for the treatment of post operative pain in a patient undergoing major orthopedic surgery. Postoperative pain is a dynamic phenomena in every patient.
- Conditions
- Injury of Foot, Shoulder or Knee, Perineural Analgesia, Pain, Postoperative
- Trial name
- MICREL (NCT02018068)
- Testing
- Remote control, At bedside care
- Where
- 4 sites in France, Netherlands and 1 more
- Volunteers
- 72 people
- Sponsor
- University Hospital, Montpellier
Virtual Reality
Virtual Reality Instructional Design in Orthopedic Physical Therapy Education
The objective of this study is to assess the effects of virtual reality instructional design on physical therapy students' clinical decision-making skills, as compared with a traditional method of instruction with the same…
- Trial name
- NCT04754568
- Testing
- Virtual reality instructional design, Role-playing instructional design
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Shenandoah University
Orthopedic Surgical Procedures, Postoperative Pain
Duration of Sciatic Nerve Block After Injection of Local Anesthetic In or Around the Nerve
This study was designed to assess whether the injection of local anesthetic into the nerve (intraneural), as opposed to around it (perineural), leads to longer anesthesia and analgesia of the leg.
- Trial name
- NCT01981291
- Testing
- Intraneural Injection for Subgluteal Sciatic Nerve Block, Perineural Injection for Subgluteal Sciatic Nerve Block, Femoral Nerve Block
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- University of Parma
Hip Osteoarthritis, Knee Osteoarthritis
Return to Golf After Orthopaedic Surgery
The GOLF study is a multicenter, prospective study with the goal to investigate golfers' return to the sport following hip, knee or shoulder arthroplasty.
- Conditions
- Hip Osteoarthritis, Knee Osteoarthritis, Shoulder Osteoarthritis
- Trial name
- NCT05675618
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 432 people
- Sponsor
- Hospital for Special Surgery, New York
Anesthesia, Time
Can the Usage of Regional Block Room Save the Time of Anesthesia Team
Study of time usage of anesthesia team inside the main operating room compares between 2 groups of Performing regional anesthesia inside the operating room Performing regional anesthesia in the block room Study purpose: How much…
- Trial name
- NCT01499589
- Testing
- regional anesthesia
- Where
- Thailand
- Volunteers
- 800 people
- Sponsor
- Mahidol University
Walking Cast Right Leg Immobilisation Effects, Aircast Right Leg Immobilisation Effects
The Effects of Lower Right Limb Orthopedic Immobilization on Driving Performance
Abstract Background: Effects of orthopedic immobilizations of the lower right limb on driving performances are unknown. Therefore, clinicians and legislators cannot put forth recommendations for road safety for patients requiring…
- Trial name
- NCT00950729
- Testing
- Driving with running shoes, Plaster cast, Driving with Aircast
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Pain in Pediatric Patients
Caudal Dexmetedomedine Versus Magnesium in Orthopedic Pediatric Surgeries
This study will be performed in Abo Elreesh Pediatric Hospital / Cairo University after obtaining approval by the University Ethics Committee, and a written informed consent from the parents or guardians.
- Trial name
- NCT03460041
- Testing
- Magnesium Sulfate, Dexmetedomedine, Bupivacaine
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Hagar hassanein refaee
Lower Limb Injury, Injury Trauma
Muscle Quality and Percentage of Fat Following a Lower Limb Injury
The aim of the study is to longitudinally evaluate patient muscle quality in trauma patients with bed rest or altered weight-bearing with the help of a consumer approved non-proprietary muscle impedance-measuring device.
- Trial name
- NCT03578705
- Testing
- Electrical Impedance Myography unit or "EIM"
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Orthopedic Trauma Surgery Patients
Digital Behavioral Pain Medicine for Orthopedic Trauma Surgery Patients
The primary purpose of this study is to determine the feasibility and preliminary efficacy of a perioperative digital behavioral pain medicine intervention delivered to orthopedic trauma surgery patients (compared to an active…
- Trial name
- NCT03764839
- Testing
- Perioperative Digital Behavioral Pian Medicine "My Surgical Success"
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Stanford University
Postoperative Cognitive Dysfunction, Orthopedic Procedures
Remimazolam vs. Midazolam for Sedation and Cognitive Outcomes in Orthopedic Surgery
This study aims to compare two medications, Remimazolam and Midazolam, used for sedation during orthopedic surgeries performed under regional anesthesia.
- Conditions
- Postoperative Cognitive Dysfunction, Orthopedic Procedures, Postoperative Pain Management, Hip Fracture
- Trial name
- REMIND-ORTHO (NCT07113483)
- Testing
- Midazolam, REMIMAZOLAM BESYLATE 2.5 Mg in 1 mL INTRAVENOUS INJECTION, POWDER, LYOPHILIZED, for SOLUTION [BYFAVO]
- Where
- Romania
- Volunteers
- 120 people
- Sponsor
- Romanian Society for Enteral and Parenteral Nutrition