Clinical trials: Orthopedic Disorder
Orthopedic Disorders
Right-Size Clinic Visits Using Memora Platform for PROMIS
Developing novel methods of patient communication is crucial in providing value-based care to orthopedic patients. Healthcare technology platforms have been developed to improve patient communication methods particularly for the…
- Trial name
- NCT04441567
- Testing
- Right-size clinic visits
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- Boston Medical Center
Orthopedic Disorder, Trauma Injury
X-BS Ortho Bone Graft Study
Randomised investigation of the osteoconductive performance and safety of CE-marked FDBS bone graft (GraftR3®), with contextual reference to CE-marked IBS (MBCP® Putty), in the filling of orthopaedic bone defects.
- Conditions
- Orthopedic Disorder, Trauma Injury, Extremity Injury
- Trial name
- NCT06326827
- Testing
- FDBS (GraftR3®), IBS (MBCP® Putty)
- Volunteers
- 200 people
- Sponsor
- Advanced Medical Solutions Ltd.
Hallux Valgus, Orthopedic Disorder
A Study to Compare Early and Partial Weight-bearing After Hallux Valgus Surgery
This is a two-arm randomized controlled trial with the aim to evaluate the effectiveness and safety of post-operative management after a modified Lapidus arthrodesis with/without an Akin or a Weil/Hohmann surgery fusion with…
- Trial name
- NCT05534724
- Testing
- Partial weight-bearing (10 - 15kg), Complete weight-bearing
- Where
- Switzerland
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Orthopedic Disorder
Accelerometry and Rehabilitation After Knee Replacement Study (ARK)
Total knee replacement (TKR) is a successful and cost-effective treatment for end-stage arthritis. Its usage is increasing due to changing population demographics and quality of life (QoL) expectations.
- Trial name
- ARK (NCT05412940)
- Testing
- Remote monitoring of home-based exercises following knee replacement using a wearable sensor, Standard Care (in control arm)
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Orthopedic Trauma, Sleep Quality
Sleep Quality and the Efficacy of a Multimodal Sleep Pathway in Hospitalized Orthopedic Trauma Patients
The goal of this study is to determine whether a multimodal sleep pathway can enhance sleep quality in hospitalized patients with orthopedic trauma.
- Trial name
- NCT07336277
- Testing
- Standard Postoperative Care, Zolpidem, Melatonin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Emory University
Postoperative Sleep Disturbance, Orthopedic Surgery Patients
Effect of ASMR and White Noise on Sleep Quality in Patients Undergoing Elective Lower Extremity Surgery
This randomized controlled trial aims to evaluate the effects of Autonomous Sensory Meridian Response (ASMR) and white noise on postoperative sleep quality in patients undergoing elective lower extremity surgery.
- Conditions
- Postoperative Sleep Disturbance, Orthopedic Surgery Patients, Sleep Quality
- Trial name
- SLEEP-ASMR (NCT07651228)
- Testing
- ASMR Audio Intervention, White Noise Audio Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- muzeyyen ataseven
Orthopedic Disorder, Anterior Cruciate Ligament Injuries
Quadriceps Tendon Versus Bone Patellar Tendon Bone Autograft ACL Reconstruction RCT
The choice of autograft for ACL reconstruction continues to be debated. To date, there has only be one completed randomized controlled trial with quad tendon to BTB and the tendon included a bone plug.
- Trial name
- NCT05461326
- Testing
- Quad tendon, BTB
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Alabama at Birmingham
Orthopedic Disorder, Humerus Fracture
Early Versus Delayed Rehabilitation After Reverse Total Shoulder Arthroplasty for Proximal Humerus Fracture
Proximal humerus fractures can be a debilitating injury in the elderly, impacting the ability to function independently or complete activities of daily living due to pain and restricted shoulder motion.
- Conditions
- Orthopedic Disorder, Humerus Fracture, Shoulder Arthroplasty, Reverse Shoulder Replacement
- Trial name
- NCT06869343
- Testing
- Physical Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Virginia
Arthropathy of Knee, Arthropathy of Hip
Pre-operative Inspiratory Muscle Strength Training in Total Joint Surgery
The purpose of this research study is to evaluate effects of respiratory strengthening exercises on breathing function, in people who have orthopedic surgery.
- Conditions
- Arthropathy of Knee, Arthropathy of Hip, Lower Extremity Fracture, Orthopedic Disorder
- Trial name
- NCT05381818
- Testing
- Daily Inspiratory Muscle Training (dIMT), Acute Inspiratory Muscle Training (aIMT), Standard of Care (SOC)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Florida
Orthopedic Disorder, Calcium Metabolism Disorders
High- Versus Low-calcium Water for Bone Health
The experimental study investigates which metabolic responses of calcium and parathyroid hormone are observable in blood and urine in a cohort of 41 healthy adults following a sequence of different exposures: low-calcium water…
- Conditions
- Orthopedic Disorder, Calcium Metabolism Disorders, Bone Resorption, Water-Electrolyte Imbalance
- Trial name
- NCT05772364
- Testing
- Loading of low-calcium water first, then high-calcium water
- Where
- Italy
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Orthopedic Disorder, Trauma
An Imaging Framework for Clinically Testing New Treatments to Prevent Post-traumatic OA
The immediate goal of the proposed research is to test the value of a new low-cost, low-dose standing CT system for efficient early detection of both joint degeneration and elevated contact stress.
- Conditions
- Orthopedic Disorder, Trauma, Ankle Fractures, Post-traumatic Osteoarthritis
- Trial name
- NCT03809520
- Testing
- pedCAT
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- J L Marsh
Orthopedic Surgery, Older Adults
Perioperative Mental Health in Orthopedic Surgery
This Hybrid 1 Study will test the effectiveness of a bundled intervention comprised of behavioral activation and medication optimization in reducing symptoms of depression and anxiety in older adults undergoing Orthopedic surgery…
- Conditions
- Orthopedic Surgery, Older Adults, Depression, Anxiety
- Trial name
- CPMH (NCT05697835)
- Testing
- Behavioral activation, Medication optimzation, Care as usual
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Washington University School of Medicine
Preoperative Anxiety, Psychological Stress
Effect of Lavender Aromatherapy on Preoperative Anxiety, Stress, and Depression in Orthopedic Surgery Patients
This study evaluates whether inhalation aromatherapy with lavender essential oil can reduce anxiety, stress, and depression in adult patients before orthopedic surgery in Jordan.
- Conditions
- Preoperative Anxiety, Psychological Stress, Depressive Symptoms, Orthopedic Surgery Patients
- Trial name
- LAV-ORTHO (NCT07513831)
- Testing
- Lavender Essential Oil Inhalation
- Where
- Jordan
- Volunteers
- 128 people
- Sponsor
- Al-Zaytoonah University of Jordan
Orthopedic Trauma Surgery Patients, Postoperative Pain
Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients
The goal of this clinical trial is to learn if ketamine, given during surgery, can help improve recovery for adults with serious orthopedic trauma.
- Conditions
- Orthopedic Trauma Surgery Patients, Postoperative Pain, Opioid Use, Depression
- Trial name
- NCT06903819
- Testing
- Ketamine, standard general anesthesia
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Texas Tech University Health Sciences Center
Orthopedic Disorder, Nontraumatic Injury
Web-based Mind-body Program to Improve Resilience Among Risky Substance Users With Persistent Upper Extremity Pain
The investigator aims to conduct a feasibility randomized controlled trial (RCT) (N=50) to test the feasibility, acceptability, and credibility of an asynchronous web-based mind-body intervention (Toolkit for Resilient Life…
- Conditions
- Orthopedic Disorder, Nontraumatic Injury, Upper Extremity Pain, Risky Substance Use
- Trial name
- NCT06991205
- Testing
- Web-TIRELESS, Web-MEUC
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Jafar Bakhshaie
Orthopedic Disorder
Testing of Mobile Monitoring System
We will complete a prospective, observational study comparing the accuracy of the mobile monitoring tool on identifying SSI compared to manual review.
- Trial name
- NCT04601376
- Testing
- Mobile Monitoring Tool
- Sponsor
- Stanford University
Orthopedic Disorder, Nontraumatic Injury
Web-based Mind-body Program for Comorbid Nontraumatic Upper-extremity Condition and Risky Substance Use
The investigator aims to conduct an open pilot study (N=6; 5 completers) to test the feasibility, acceptability, and credibility of an asynchronous web-based mind-body intervention (Toolkit for Resilient Life beyond Pain and…
- Conditions
- Orthopedic Disorder, Nontraumatic Injury, Substance Use, Upper Extremity Problem
- Trial name
- NCT06366633
- Testing
- Web-TIRELESS
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Jafar Bakhshaie
Orthopedic Disorder
The Duration of Spinal Anaesthesia - a Prospective, Observational Cohort Study
Today, surgery in an ambulatory setting is preferred for many reasons. Total hip and knee arthroplasty (THA and TKA) are now procedures where patients can be sent home on the same day of the surgical procedure.
- Trial name
- Spinalrocks (NCT06459986)
- Where
- 2 sites in Denmark
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Patella Fracture, Surgery
Tension Band Versus Locking Plate Fixation for the Treatment of Patella Fractures
This study is a multicenter pragmatic, prospective, assessor-blinded, randomized independent clinical trial in which we compare locking plate fixation to standard tension band fixation in patients with patella fractures.
- Conditions
- Patella Fracture, Surgery, Orthopedic Disorder
- Trial name
- TENPLA (NCT04891549)
- Testing
- Tension band fixation, Plate fixation
- Where
- 6 sites in Denmark
- Volunteers
- 122 people
- Sponsor
- Rasmus Elsøe
Orthopedic Disorder, Thoracic
Epidemiological Data on Pain
The ALGOBASES project is an observational epidemiological study of pain through the collection of pain evaluation questionnaires and information with the aim of creating a descriptive "pain" evaluation in all patients who need to…
- Conditions
- Orthopedic Disorder, Thoracic, Gynecological; Surgery (Previous), Causing Obstructed Labor, Affecting Fetus, Pain
- Trial name
- ALGOBASES (NCT04546594)
- Sponsor
- University Hospital, Lille