Clinical trials: Orthopedic Disorder, active
Constipation, Perioperative Nursing
Effect of a Constipation Prevention Checklist in Hip Surgery Patients
Constipation is a common postoperative problem in patients undergoing hip surgery and may be associated with immobilization, opioid analgesic use, and inadequate fluid and fiber intake.
- Conditions
- Constipation, Perioperative Nursing, Checklist, Orthopedic Disorder
- Trial name
- NCT07895316
- Testing
- Constipation prevention and checklist monitoring in hip surgery patients
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Orthopedic Disorders
Right-Size Clinic Visits Using Memora Platform for PROMIS
Developing novel methods of patient communication is crucial in providing value-based care to orthopedic patients. Healthcare technology platforms have been developed to improve patient communication methods particularly for the…
- Trial name
- NCT04441567
- Testing
- Right-size clinic visits
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- Boston Medical Center
Orthopedic Disorder, Trauma Injury
X-BS Ortho Bone Graft Study
Randomised investigation of the osteoconductive performance and safety of CE-marked FDBS bone graft (GraftR3®), with contextual reference to CE-marked IBS (MBCP® Putty), in the filling of orthopaedic bone defects.
- Conditions
- Orthopedic Disorder, Trauma Injury, Extremity Injury
- Trial name
- NCT06326827
- Testing
- FDBS (GraftR3®), IBS (MBCP® Putty)
- Volunteers
- 200 people
- Sponsor
- Advanced Medical Solutions Ltd.
Hallux Valgus, Orthopedic Disorder
A Study to Compare Early and Partial Weight-bearing After Hallux Valgus Surgery
This is a two-arm randomized controlled trial with the aim to evaluate the effectiveness and safety of post-operative management after a modified Lapidus arthrodesis with/without an Akin or a Weil/Hohmann surgery fusion with…
- Trial name
- NCT05534724
- Testing
- Partial weight-bearing (10 - 15kg), Complete weight-bearing
- Where
- Switzerland
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Orthopedic Disorder
Accelerometry and Rehabilitation After Knee Replacement Study (ARK)
Total knee replacement (TKR) is a successful and cost-effective treatment for end-stage arthritis. Its usage is increasing due to changing population demographics and quality of life (QoL) expectations.
- Trial name
- ARK (NCT05412940)
- Testing
- Remote monitoring of home-based exercises following knee replacement using a wearable sensor, Standard Care (in control arm)
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Orthopedic Trauma, Sleep Quality
Sleep Quality and the Efficacy of a Multimodal Sleep Pathway in Hospitalized Orthopedic Trauma Patients
The goal of this study is to determine whether a multimodal sleep pathway can enhance sleep quality in hospitalized patients with orthopedic trauma.
- Trial name
- NCT07336277
- Testing
- Standard Postoperative Care, Zolpidem, Melatonin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Emory University
Postoperative Sleep Disturbance, Orthopedic Surgery Patients
Effect of ASMR and White Noise on Sleep Quality in Patients Undergoing Elective Lower Extremity Surgery
This randomized controlled trial aims to evaluate the effects of Autonomous Sensory Meridian Response (ASMR) and white noise on postoperative sleep quality in patients undergoing elective lower extremity surgery.
- Conditions
- Postoperative Sleep Disturbance, Orthopedic Surgery Patients, Sleep Quality
- Trial name
- SLEEP-ASMR (NCT07651228)
- Testing
- ASMR Audio Intervention, White Noise Audio Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- muzeyyen ataseven
Orthopedic Disorder, Anterior Cruciate Ligament Injuries
Quadriceps Tendon Versus Bone Patellar Tendon Bone Autograft ACL Reconstruction RCT
The choice of autograft for ACL reconstruction continues to be debated. To date, there has only be one completed randomized controlled trial with quad tendon to BTB and the tendon included a bone plug.
- Trial name
- NCT05461326
- Testing
- Quad tendon, BTB
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Alabama at Birmingham
Orthopedic Disorder, Humerus Fracture
Early Versus Delayed Rehabilitation After Reverse Total Shoulder Arthroplasty for Proximal Humerus Fracture
Proximal humerus fractures can be a debilitating injury in the elderly, impacting the ability to function independently or complete activities of daily living due to pain and restricted shoulder motion.
- Conditions
- Orthopedic Disorder, Humerus Fracture, Shoulder Arthroplasty, Reverse Shoulder Replacement
- Trial name
- NCT06869343
- Testing
- Physical Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Virginia
Arthropathy of Knee, Arthropathy of Hip
Pre-operative Inspiratory Muscle Strength Training in Total Joint Surgery
The purpose of this research study is to evaluate effects of respiratory strengthening exercises on breathing function, in people who have orthopedic surgery.
- Conditions
- Arthropathy of Knee, Arthropathy of Hip, Lower Extremity Fracture, Orthopedic Disorder
- Trial name
- NCT05381818
- Testing
- Daily Inspiratory Muscle Training (dIMT), Acute Inspiratory Muscle Training (aIMT), Standard of Care (SOC)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Florida
Orthopedic Trauma Surgery Patients, Postoperative Pain
Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients
The goal of this clinical trial is to learn if ketamine, given during surgery, can help improve recovery for adults with serious orthopedic trauma.
- Conditions
- Orthopedic Trauma Surgery Patients, Postoperative Pain, Opioid Use, Depression
- Trial name
- NCT06903819
- Testing
- Ketamine, standard general anesthesia
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Texas Tech University Health Sciences Center
Orthopedic Disorder, Nontraumatic Injury
Web-based Mind-body Program to Improve Resilience Among Risky Substance Users With Persistent Upper Extremity Pain
The investigator aims to conduct a feasibility randomized controlled trial (RCT) (N=50) to test the feasibility, acceptability, and credibility of an asynchronous web-based mind-body intervention (Toolkit for Resilient Life…
- Conditions
- Orthopedic Disorder, Nontraumatic Injury, Upper Extremity Pain, Risky Substance Use
- Trial name
- NCT06991205
- Testing
- Web-TIRELESS, Web-MEUC
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Jafar Bakhshaie
Orthopedic Disorder
The Duration of Spinal Anaesthesia - a Prospective, Observational Cohort Study
Today, surgery in an ambulatory setting is preferred for many reasons. Total hip and knee arthroplasty (THA and TKA) are now procedures where patients can be sent home on the same day of the surgical procedure.
- Trial name
- Spinalrocks (NCT06459986)
- Where
- 2 sites in Denmark
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Neurological Disorders, Orthopedic Disorders
A Model for Continuous Care of Fragile Patients
This observational study aims to monitor functional status and identify potential declines in the functioning of medically fragile patients with neurological and/or orthopedic conditions, representing an added value for ensuring…
- Conditions
- Neurological Disorders, Orthopedic Disorders, Functional Decline, Fragile and More Vulnerable
- Trial name
- AFTER (NCT07299344)
- Testing
- Telemedicine-Based Functional Monitoring
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Azienda Sanitaria Locale CN2 Alba-Bra
Fracture, Lengthening; Leg
Pediatric Orthopaedic Implant Safety & Efficacy
Implant devices are important tools - their use is essential across a number of orthopaedic indications, including hip conditions, trauma and limb deformity.
- Conditions
- Fracture, Lengthening; Leg, Orthopedic Disorder, Deformity of Limb
- Trial name
- Global POISE (NCT05361980)
- Testing
- Pediatric orthopaedic implant
- Where
- Canada
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Intraoperative Blood Loss, Pediatric
Tranexamic Acid in Pediatric Undergoing Proximal Femoral Osteotomies and/or Acetabular Osteotomy
Surgical hip reconstruction reduces the hip joint through soft tissue releases and osteotomies of the femur and/or pelvis. Blood loss and subsequent blood transfusion are normal consequences of hip reconstruction.
- Conditions
- Intraoperative Blood Loss, Pediatric, Orthopedic Disorder
- Trial name
- NCT04811313
- Testing
- Tranexamic acid, caudal epidural block
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Assiut University
Orthopedic Disorder, Retained Metal Implant
Metallosis on Tissues and Serum Metal Levels in Children
Slightly elevated blood metal levels have been found in adults undergoing hip and knee replacement. It is unknown whether pediatric patients with metal implant(plates/screws/rods) have elevated blood metal levels.
- Trial name
- NCT03359109
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Orthopedic Disorder
CERAMENT™| Bone Void Filler Device Registry
A device registry to compile data on the performance of CERAMENT BONE VOID FILLER in normal use.
- Trial name
- NCT04244942
- Testing
- CERAMENT BVF
- Where
- 13 sites in United States
- Volunteers
- 300 people
- Sponsor
- BONESUPPORT AB
Orthopedic Disorder
Clinical and Radiological Evaluation of Total Ankle Replacement (ProtesiTT)
Numerous studies reported the efficacy of new third-generation of total ankle arthroplasties for the treatment of advanced ankle osteoarthritis and clinical results are comparable to ankle arthrodesis.
- Trial name
- ProtesiTT (NCT07168330)
- Testing
- Ankle replacement
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Orthopedic Disorder
SupraScapular Cuff Study: Assessing the Effects of Size and Type of Rotator Cuff Tear on Suprascapular Nerve Function
The primary objective of the study is to determine in adult patients with a rotator cuff tear, what size and pattern of rotator cuff tear would result in damage to the suprascapular nerve. The secondary objectives are 1.
- Trial name
- SSCuFF (NCT06002009)
- Testing
- MRI, Nerve conduction study
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- University Hospitals of North Midlands NHS Trust