Clinical trials: Orthopedic Injury
Hip Injuries, Tendon Injuries
Evaluation of Healing Following Open Gluteus Medius Repair With Biointegrative Implant
This is a prospective, single-center study design with enrollment of 15 subjects. The 15 subjects will all undergo standard gluteus medius repair that includes augmentation with the biointegrative implant.
- Conditions
- Hip Injuries, Tendon Injuries, Orthopedic Procedures
- Trial name
- NCT05492396
- Testing
- Standard gluteus medius repair with Tapestry Biointegrative implant
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Ohio State University
Infections
A Multi-Center Protocol for Obtaining and Storing Human Samples for Immediate or Future Microbial, Immune, or Host-Microbe Scientific Study
The intent of this protocol is to salvage human-related material that is normally destined for destruction, so it can be used in infection-related scientific studies.
- Trial name
- NCT00764023
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Southwest Regional Wound Care Center
Surgical Wound Infection
Sutures Versus Staples for Wound Closure in Orthopaedic Surgery
The trial is a randomized, controlled trial. Adult patients undergoing orthopaedic surgical procedures would be randomized to one of two groups for surgical wound closure, skin sutures or skin staples.
- Trial name
- NCT01146236
- Testing
- Sutures, Staples
- Where
- 3 sites in Canada
- Volunteers
- 247 people
- Sponsor
- University of Manitoba
Orthopaedic Fractures, Socioeconomic Factors
Trial of Social Work Services in Fracture Clinic Setting
Every year, many Canadians sustain a fracture that requires surgical treatment and results in a long recovery period. During this recovery period, patients may experience new or worsening mental health issues including…
- Trial name
- SWRCT (NCT06973655)
- Testing
- Social Work support
- Where
- 2 sites in United States, Canada
- Volunteers
- 2,000 people
- Sponsor
- Sheila Sprague
Surgical Wound
Regenn® Therapy System Safety Study
The goal of this clinical trial is to evaluate the safety of the investigational device, Regenn® Negative Pressure Therapy System (Regenn® Therapy), a form of Negative Pressure Wound Therapy (NPWT), in the post-operative surgical…
- Trial name
- NCT06259409
- Testing
- Regenn® Negative Pressure Therapy System, Prevena™ Incision Management System
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Progenerative Medical, Inc
High-energy Trauma, Sacral Fractures
The Difference of Two and Three Fluoroscopic Views of Sacrum for Percutaneous Sacroiliac Screw Insertion in High Energy Posterior Pelvic Ring Injured Patients
The goal of this clinical trial is to learn about the surgical techniques of percutaneous sacroiliac screw fixation both the two-view fluoroscopic technique (sacral inlet and outlet views) and the standard three-view fluoroscopic…
- Conditions
- High-energy Trauma, Sacral Fractures, Posterior Pelvic Ring Injury
- Trial name
- NCT07571798
- Testing
- Percutaneous sacroiliac screw fixation using two or three fluoroscopic views
- Where
- Thailand
- Volunteers
- 16 people
- Sponsor
- Chonburi hospital
Pain, Postoperative
Safety and Efficacy of Repeated Doses of PMI-150 (Intranasal Ketamine) in Acute Post-operative Pain Following Orthopedic Surgery
The purpose of this research study is to evaluate the safety and analgesic efficacy of PMI-150 (intranasal ketamine) compared to placebo in patients with acute post-operative pain following orthopedic trauma, injury, or surgery.
- Trial name
- NCT00709436
- Testing
- PMI-150 (intranasal ketamine)
- Where
- 16 sites in United States
- Volunteers
- 250 people
- Sponsor
- Hospira, now a wholly owned subsidiary of Pfizer
Fracture; Complication Orthopedic Procedure
The Effect of Using a Kaleidoscope on Fear and Pain in Children
The research was conducted in randomized controlled experimental type between May 2022 and December2023. The universe of the research consisted of children and their parents who were diagnosed with a fracture, applied to the…
- Trial name
- NCT06261112
- Testing
- kaleidescope
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mihriban Culha
Distal Radius Fractures, Wrist Fractures
Supraclavicular Bupivacaine Vs. Supraclavicular Liposomal Bupivacaine for Orthopedic Wrist Surgery
Orthopedic wrist procedures often cause significant postoperative pain. A supraclavicular nerve block is an effective and proven method to help reduce postoperative pain and decrease opioid use around the time of upper extremity…
- Trial name
- Vs (NCT06179004)
- Testing
- Liposomal bupivacaine, Bupivacaine Hydrochloride
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Fracture Dislocation
Study of PLGA-Mg Material in Clinical Orthopedics
The different proportion samples of PLGA-Mg were made in this study. Then, they would be placed in the femoral condyle of the New Zealand rabbits.
- Trial name
- NCT03060655
- Testing
- PLGA-Mg material, titanium alloy
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hebei Medical University Third Hospital
Sleep Disturbance, Trauma
Treatment for Sleep Disturbance in Orthopaedic Trauma Patients
The purpose of the study is to test the efficacy of sleep treatment in human patients following traumatic injury. Specifically, the study will determine if treatment consisting of melatonin and education related to sleep habits…
- Trial name
- NCT03779243
- Testing
- Melatonin 5mg and Sleep Education
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Stanford University
Carpal Tunnel Syndrome
Length of Post Operative Dressing After Carpal Tunnel Release
The purpose of the study is to prospectively compare the functional, satisfaction, and wound outcomes of patients treated with one of two accepted methods of postoperative dressing following carpal tunnel release.
- Trial name
- NCT01310218
- Testing
- extended postoperative dressing, short postoperative dressing
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- UConn Health
Knee Arthroplasty
First Mobilization Protocol for Total Knee Arthroplasty Patients
This single blinded randomized controlled study evaluates the effect of developed First Mobilization Protocol applied to knee arthroplasty patients on state anxiety, kinesiophobia, initial mobilization related symptoms.
- Trial name
- NCT06268899
- Testing
- First mobilization protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Gazi University
Trauma, Orthopedic Surgery Complications
The Infected Bone Nonunion and Soft Tissue Defect of Long Bone Treated Simultaneously With Ilizarov Technique
In this retrospective study, the investigators evaluated the clinical and functional results of infected nonunion of the long bone with soft-tissue defects treated simultaneously with Ilizarov technique combining open dressing…
- Trial name
- NCT00846261
- Testing
- Use it to treatment bone nonunion (Ilzarov)
- Where
- China
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Orthopedic Disorder, Post Operative Pain
TENS for Relief of Postoperative Pain in Orthopedic Patients
To ensure early mobilization, minimize suffering, and to prevent postoperative complications postoperative pain should be reduced as soon and as effectively as possible.
- Conditions
- Orthopedic Disorder, Post Operative Pain, Hip Fractures, Arthroplasty, Replacement, Hip
- Trial name
- NCT05678101
- Testing
- transcutaneous electrical nerve stimulation (TENS)
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska University Hospital
Ligament Knee Injury, Anterior Cruciate Ligament Rupture
Optimized Rehabilitation After Anterior Cruciate Ligament Before Returning to Sport
Following reconstruction of the anterior cruciate ligament (ACL), a standardized rehabilitation protocol is carried out by a physiotherapist.
- Trial name
- ORACL-Run (NCT05323474)
- Testing
- Usual rehabilitation, Rehabilitation optimized
- Where
- 8 sites in France, Switzerland
- Volunteers
- 432 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Pain, Postoperative
Intraoperative Methadone vs Morphine for Postoperative Pain Control in Patients Undergoing Surgery of the Tibia
The purpose of this study is to determine whether, for surgery of the tibia, one dose of methadone provides better control of pain afterward as compared to morphine, which is the usual drug given to control pain after surgery.
- Trial name
- NCT01430182
- Testing
- Methadone, Morphine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Baylor College of Medicine
Tibial Fractures
Use of a Reinforced Injectable Calcium Phosphate Bone Cement in the Treatment of Tibial Plateau Fractures
Case series of tibial plateau fractures using Norian Drillable.
- Trial name
- NCT01132508
- Testing
- Norian Drillable Bone Void Filler
- Where
- 6 sites in Australia, China and 2 more
- Volunteers
- 33 people
- Sponsor
- Synthes GmbH
Infection
A Multi-Center Protocol for Obtaining and Storing Human Samples for Immediate or Future Microbial, Immune, or Host Microbe Scientific Study
The intent of this protocol is to salvage human-related material that is normally destined for destruction, so it can be used in infection-related scientific studies.
- Trial name
- NCT00765141
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Southwest Regional Wound Care Center
Draining Hematoma
Vacuum Assisted Closure as a Treatment for Draining Hematomas
This project is designed as a prospective, randomized, comparative study evaluating the use of a negative pressure vacuum device in treating draining hematomas following traumatic injury.
- Trial name
- VAC-DH (NCT00582179)
- Testing
- Standard Pressure Dressing, VAC
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- University of Alabama at Birmingham